• Title/Summary/Keyword: Ring Hybrid

Search Result 140, Processing Time 0.023 seconds

Genetically Engineered Biosynthesis of Macrolide Derivatives Including 4-Amino-4,6-Dideoxy-L-Glucose from Streptomyces venezuelae YJ003-OTBP3

  • Pageni, Binod Babu;Oh, Tae-Jin;Liou, Kwang-Kyoung;Yoon, Yeo-Joon;Sohng, Jae-Kyung
    • Journal of Microbiology and Biotechnology
    • /
    • v.18 no.1
    • /
    • pp.88-94
    • /
    • 2008
  • Two sugar biosynthetic cassette plasm ids were used to direct the biosynthesis of a deoxyaminosugar. The pOTBP1 plasmid containing TDP-glucose synthase (desIII), TDP-glucose-4,6-dehydratase (desIV), and glycosyltransferase (desVII/desVIII) was constructed and transformed into S. venezuelae YJ003, a strain in which the entire gene cluster of desosamine biosynthesis is deleted. The expression plasmid pOTBP3 containing 4-aminotransferase (gerB) and 3,5-epimerase (orf9) was transformed again into S. venezuelae YJ003-OTBP1 to obtain S. venezuelae YJ003-OTBP3 for the production of 4-amino-4,6-dideoxy-L-glucose derivatives. The crude extracts obtained from S. venezuelae ATCC 15439, S. venezuelae YJ003, and S. venezuelae YJ003-OTBP3 were further analyzed by TLC, bioassay, HPLC, ESI/MS, LC/MS, and MS/MS. The results of our study clearly shows that S. venezuelae YJ003-OTBP3 constructs other new hybrid macrolide derivatives including 4-amino-4,6-dideoxy-L-glycosylated YC-17 (3, [M+ $Na^+$] m/z=464.5), methymycin (4, m/z=480.5), novamethymycin (6, m/z=496.5), and pikromycin (5, m/z=536.5) from a 12-membered ring aglycon (10-deoxymethynolide, 1) and a 14-membered ring aglycon (narbonolide, 2). These results suggest a successful engineering of a deoxysugar pathway to generate novel hybrid macrolide derivatives, including deoxyaminosugar.

Efficient simulation method for a gas inflow to the central molecular zone

  • Shin, Jihye;Kim, Sungsoo S.;Baba, Junichi;Saitoh, Takayuki R.;Chun, Kyungwon;Hozumi, Shunsuke
    • The Bulletin of The Korean Astronomical Society
    • /
    • v.40 no.1
    • /
    • pp.59.1-59.1
    • /
    • 2015
  • We present hydrodynamic simulations of gas clouds that inflowing from the disk to a few hundred parsec region of the Milky Way. Realistic Galactic structures are included in our simulations by thousands of multipole expansions that describe 6.4 million stellar particles of a self-consistent Galaxy simulation (Baba, Saitoh & Wada, in prep.). We find that a hybrid multipole expansion model with two different basis sets and a thick disk correction well reproduces the overall structures of the Milky Way. We find that the nuclear ring evolves into 240 pc at T~1500 Myr, regardless of the initial size. For most of simulation runs, gas inflow rate to the nuclear region is equilibrated as ~0.02 Msun/yr, and thus accumulated gas mass and star formation activity is stabilized as $6{\times}10^7Msun$ and ~0.02M/yr, respectively. These stabilized values are in a good agreement with estimations for the CMZ. The nuclear ring is off-centered to the Galactic center by the lopsided central mass distribution of the Galaxy model, and thus an asymmetric mass distribution is arose accordingly. The lopsidedness also leads the nuclear ring to be tilted to the Galactic plane and to precess along the Galaxy rotation. In early evolutionary stage when gas clouds start to inflow and form the nuclear ring, the z-directional oscillations of the gas clouds results in the twisted, infinity-shaped nuclear ring. Since the infinity-shaped feature is transient only for first 100 Myr, the current infinity-shape observed in the CMZ may indicate that the CMZ forms quite recently.

  • PDF

Fabrication of the (Alnico, Sm-Co) Bonded Magnet and its Magnetic Properties ((알니코, 사마리움-코발트) 본드자석의 제조 및 자기적 특성연구)

  • Kim, Jung-Sik
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
    • /
    • v.23 no.12
    • /
    • pp.988-995
    • /
    • 2010
  • In this study the (Alnico, Sm-Co) bonded magnets were fabricated by mixing the Sm-Co added alnico alloy powders with epoxy resin and binder, appropriately. Also, the hybrid ring magnets of (Alnico, Sm-Co)/Sr-ferrite were fabricated by coupling the Sr-ferrite composite layer with an (Alnico, Sm-Co) magnet. The magnetic properties of (Alnico, Sm-Co) ring magnets were varied with the amount of Sm-Co powders. The addition of Sm-Co powders increased a remanent induction($B_r$) and coercive force($_BH_C$), while decreasing a surface flux density and repulsive distance. The surface flux density and repulsive distance for the (Alnico, Sm-Co) ring magnet increased with a magnetizing voltage up to about 160 V and reached an apparent saturation point. Also, the measurements of temperature and moisture characteristics showed that the surface flux densities of N-S poles and repulsive distance decreased a little within 4% after 10 days passed.

Design of New Hybrid-Ring Directional Coupler Using λ/6 Sections (λ/6선로를 이용한 새로운 형식의 하이브리드 링 방향성 결합기의 설계)

  • 양규식;이종악;김동일
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.16 no.3
    • /
    • pp.275-283
    • /
    • 1991
  • A design method of the new 7${\lambda}$/6 ring 3dB directional coupler using fundamental /6-sections is proposed and its frequency characteristics are analyzed. Furthermore, the experimental verification has been achieved in microstrip network, and hence, the validity of the design method of a microwave compoennt with the basic ${\lambda}$/6-sections proposed in this paper is confirmed.

  • PDF

Oscillator Design and Fabrication using a Miniatured Hairpin Resonator

  • Kim, Jang-Gu;Han, Sok-Kyun;Park, Hyung-Ha
    • Journal of Navigation and Port Research
    • /
    • v.28 no.4
    • /
    • pp.293-297
    • /
    • 2004
  • In this papers, an S-band oscillator of the low phase noise property using a miniaturized micro-strip hairpin shaped ring resonator is presented The substrate has a dielectric constant $\epsilon_\gamma$=3.5, a thickness h=0.508 mm, and loss tangent $tan\delta$=0.002. A designed and fabricated oscillator shows low phase noise performance of 99. 71 dBc/Hz at 100 KHz offset frequency and of output power 19.584 dBm at center frequency 2.450 GHz. This circuit was fabricated with hybrid technique, but can be fully compatible with the MMIC due to its entirely planar structure.

Structure Elucidation and Antibacterial Activity of Oxazolomycin Family KSM-2690 B Derived from Actinomycete Collected in Jeju Island (제주도 방선균 유래 oxazolomycin 계열 KSM-2690 B의 구조 결정과 항균활성에 관한 연구)

  • Hyeongju Jeong;Jooyoung Kim;Soohyun Um;Kyuho Moon
    • Korean Journal of Pharmacognosy
    • /
    • v.54 no.1
    • /
    • pp.16-20
    • /
    • 2023
  • KSM-2690 B (1), a peptide-polyketide hybrid compound, was discovered from an actinomycete strain (CJD 1) isolated from Dong-Baek hill on Jeju Island, Republic of Korea. The chemical structure of 1 was identified by using NMR, MS, and UV spectroscopic analyses. Careful analysis of 1D and 2D NMR data revealed that KSM-2690 (1) has an oxazole ring, a β-lactone-γ-lactam spirocycle ring, and both triene and diene structures. KSM-2690 B (1) showed inhibitory activities against E. coli at 200 ㎍/mL.

High-performance 94 GHz Single Balanced Mixer Based On 70 nm MHEMT And DAML Technology (70 nm MHEMT와 DAML 기술을 이용한 우수한 성능의 94 GHz 단일 평형 혼합기)

  • Kim Sung-Chan;An Dan;Lim Byeong-Ok;Beak Tae-Jong;Shin Dong-Hoon;Rhee Jin-Koo
    • Journal of the Institute of Electronics Engineers of Korea SD
    • /
    • v.43 no.4 s.346
    • /
    • pp.8-15
    • /
    • 2006
  • In this paper, the 94 GHz, low conversion loss, and high isolation single balanced mixer is designed and fabricated using GaAs-based metamorphic high electron mobility transistors (MHEMTs) with 70 nm gate length and the hybrid ring coupler with the micromachined transmission lines, dielectric-supported air-gapped microstrip lines (DAMLs). The 70 nm MHEMT devices exhibit DC characteristics with a drain current density of 607 mA/mm an extrinsic transconductance of 1015 mS/mm. The current gain cutoff frequency ($f_T$) and maximum oscillation frequency ($f_{max}$) are 320 GHz and 430 GHz, respectively. The fabricated hybrid ring coupler shows wideband characteristics of the coupling loss of $3.57{\pm}0.22dB$ and the transmission loss of $3.80{\pm}0.08dB$ in the measured frequency range of 85 GHz to 105 GHz. This mixer shows that the conversion loss and isolation characteristics are $2.5dB{\sim}>2.8dB$ and under -30 dB, respectively, in the range of $93.65GHz{\sim}94.25GHz$. At the center frequency of 94 GHz, this mixer shows the minimum conversion loss of 2.5 dB at a LO power of 6 dBm To our knowledge, these results are the best performances demonstrated from 94 GHz single balanced mixer utilizing GaAs-based HEMTs in terms of conversion loss as well as isolation characteristics.

The variable power divider circuit to use the ring-hybrid coupler (링-하이브리드 커플러를 이용한 가변 전력 분배기 회로)

  • Park, Ung-hee
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.20 no.2
    • /
    • pp.253-259
    • /
    • 2016
  • This paper introduces a new variable power divider circuit with an arbitrary power division ratio ranging from $1:{\infty}$ to ${\infty}:1$. The proposed power divider circuit consists of one branch-line coupler to be a good input matching characteristic, two variable phase shifters with 90-degree phase variation to be connected two output paths of the branch-line coupler, and one ring-hybrid coupler to combine output signals of two variable phase shifter. The power division ratio between the two output ports of the proposed power divider can be easily controlled by the phase variation of the two phase shifter. The proposed power divider circuit fabricates on laminated RF-35 (h = 20 mil, er=3.5; Taconic) with a center frequency of 2 GHz. The power division ratio of the fabricated prototype varies from about 1:1000 to 5000000:1, with an input reflection characteristic(S11) of below -20 dB, an insertion loss of about -1.0 dB, and an isolation characteristic of below -17 dB between two output ports in the range 1.9-2.1 GHz.

A Study on the Production of Supporting Ring Using Casting for Public Environmental Vehicles (대중적 환경차를 위한 주조를 이용한 서포트링 제작에 관한 연구)

  • Jeongick Lee
    • Journal of Advanced Technology Convergence
    • /
    • v.2 no.3
    • /
    • pp.17-24
    • /
    • 2023
  • I am designing a research paper with the aim of studying hybrid vehicles. Hybrid vehicles, as the next-generation automobiles, feature a combination of internal combustion engines and battery engines, resulting in a revolutionary reduction in fuel consumption and harmful gas emissions compared to conventional vehicles. The electric motor in hybrid cars derives power from a high-voltage battery installed within the vehicle, which is recharged during vehicle motion. In contrast to traditional cars, which often experience energy losses due to idling caused by traffic congestion, hybrid systems optimize efficiency by skillfully managing the interplay between the internal combustion engine and the electric motor. This approach effectively addresses the inherent drawbacks of gasoline or diesel engines.Hybrid cars offer an array of benefits, including improved fuel efficiency, environmental friendliness, cost-effectiveness, and reduced noise emission. Consequently, they are progressively becoming a favored alternative among a growing number of individuals. This research endeavor has the potential to contribute towards curbing environmental pollution and dedicating efforts to future automotive research.

Control of a Three-pole Hybrid Active Magnetic Bearing using Redundant Coordinates (잉여좌표계를 이용한 3-폴 하이브리드형 자기베어링 제어)

  • Park, Sang-Hyun;Lee, Chong-Won
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
    • /
    • 2007.11a
    • /
    • pp.1375-1381
    • /
    • 2007
  • In this paper, we propose a linear modeling and identical PD controller design scheme for the three-pole hybrid-type AMB recently developed in the laboratory, which consists of three permanent magnets, providing bias flux, three Hall diodes, measuring rotor displacements, and ring type permanent magnet bearing, stabilizing in axial and tilting directions. Along the three physical coordinates formed by three poles, we introduce the redundant coordinate system and three identical decoupled controllers to construct linear model. The experiments are also carried out in order to verify the effectiveness of proposed controller in stabilizing the transient and steady state response of rotor.

  • PDF