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Two Cases of Invasive Pseudomonas aeruginosa Infection that Developed in the Apparently Immunocompetent Infants (면역 기능의 이상이 발견되지 않은 영아에서의 침습성 녹농균 감염증 2례)

  • Kang, Min Jae;Kim, So Hee;Kim, Nam Hee;Lee, Jin-A;Eun, Byung Wook;Choi, Eun Hwa;Lee, Hoan Jong
    • Pediatric Infection and Vaccine
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    • v.13 no.2
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    • pp.180-185
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    • 2006
  • Invasive Pseudomonas infections most often occur in the immunocompromised patients and are associated with high mortality rate. Rarely this disease may develop in healthy infants and children. We report two cases of invasive Pseudomonas aeruginosa infections that were diagnosed in otherwise healthy infants. The first case was a previously healthy 5-month-old infant with ecthyma gangrenosum and septicemia. She presented with fever, swelling of left periorbital area and multiple erythronodular skin lesions. Each skin lesion formed a black eschar surrounded by an erythematous areola over time. Cultures of blood, urine and discharge from skin lesions grew P. aeruginosa. On the day of visit, she showed pancytopenia which was normalized after 10 days. The patient responded well to the management with ceftazidime and tobramycin. The other case was a previously healthy 9-month-old infant with community-acquired pneumonia. He was referred from an outside hospital with fever and cough. Chest x-ray revealed pneumonic infiltrations on both lower lungs with pleural effusion on the right side. Cultures of blood and pleural fluid grew P. aeruginosa. Chest CT performed on the ninth day demonstrated pneumatoceles, lung abscess and necrosis of lung parenchyma. He was managed with ceftazidime and amikacin for 50 days. No residual pulmonary complications were noted during the three month follow-up. Laboratory results to evaluate immunologic defects of phagocytic cells, complement components and T- and B-lymphocytes were all within normal range in both patients. It should be kept in mind that Pseudomonas can be, though uncommon, a cause of community-acquired invasive infections in the previously healthy infants.

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The strong association of left-side heart anomalies with Kabuki syndrome

  • Yoon, Ja Kyoung;Ahn, Kyung Jin;Kwon, Bo Sang;Kim, Gi Beom;Bae, Eun Jung;Noh, Chung Il;Ko, Jung Min
    • Clinical and Experimental Pediatrics
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    • v.58 no.7
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    • pp.256-262
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    • 2015
  • Purpose: Kabuki syndrome is a multiple congenital malformation syndrome, with characteristic facial features, mental retardation, and skeletal and congenital heart anomalies. However, the cardiac anomalies are not well described in the Korean population. We analyzed the cardiac anomalies and clinical features of Kabuki syndrome in a single tertiary center. Methods: A retrospective analysis was conducted for a total of 13 patients with Kabuki syndrome. Results: The median age at diagnosis of was 5.9 years (range, 9 days to 11 years and 8 months). All patients showed the characteristic facial dysmorphisms and congenital anomalies in multiple organs, and the diagnosis was delayed by 5.9 years (range, 9 days to 11 years and 5 months) after the first visit. Noncardiac anomalies were found in 84% of patients, and congenital heart diseases were found in 9 patients (69%). All 9 patients exhibited left-side heart anomalies, including hypoplastic left heart syndrome in 3, coarctation of the aorta in 4, aortic valve stenosis in 1, and mitral valve stenosis in 1. None had right-side heart disease or isolated septal defects. Genetic testing in 10 patients revealed 9 novel MLL2 mutations. All 11 patients who were available for follow-up exhibited developmental delays during the median 4 years (range, 9 days to 11 years 11 months) of follow-up. The leading cause of death was hypoplastic left heart syndrome. Conclusion: Pediatric cardiologist should recognize Kabuki syndrome and the high prevalence of left heart anomalies with Kabuki syndrome. Genetic testing can be helpful for early diagnosis and counseling.

Oral health knowledge level on oral care and elder oral hygiene care of the nursing home staff in long-term care facilities (노인요양시설 요양보호사의 구강관리 및 노인구강위생관리에 따른 구강보건지식 수준)

  • Kim, Kyung-Min;Park, Young-Nam;Lee, Min-Kyung;Lee, Jung-Hwa;Yoon, Hyun-Seo;Jin, Hye-Jung;Kim, Hye-Jin
    • Journal of Korean society of Dental Hygiene
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    • v.14 no.5
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    • pp.723-730
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    • 2014
  • Objectives : This research was conducted to investigate geriatric care workers' oral care, and the oral care conditions of residents of elder care facilities in relation to workers' knowledge of oral care. Methods : A survey was conducted from November 2011 to February 2012 with geriatric-care workers in elder care facilities located in Busan and other areas of Gyeongsangnam-do. Results : With regard to their oral self-care practices, 52.5% of the geriatric workers "brushed their teeth from top to bottom" and 58.1% brushed their teeth 3 times a day. Further, 52.0% did not use any oral care products, while 36.5% used Mouthrinese. The workers who brushed their teeth in their own ways or from top to bottom had significantly higher oral care knowledge scores than those who brushed from left to right (p<.05). Concerning oral hygiene care for residents, 72.6% of the geriatric workers recommended that elders visit dentists for oral care, 96.6% helped elders oral wash their teeth every day, and 54.7% used oral care products for the elders. The workers who did not recommend visits to dental clinics scored slightly higher than those who did (p<.05). Additionally, those who did not help elders oral wash their teeth scored significantly higher than those who did (p<.05). Except for oral wash to recuperated old man and recommendation of visiting the dentist, relation between oral care and knowledge about oral health and oral hygiene care is plus mutual relation. Conclusions : To manage the accuracy and quality of oral care work performed by geriatric care workers in elder care facilities, enhancing standard training and education on oral care is necessary. Providing systematic, regular education on such knowledge and practices would also be essential.

Toxic Optic Neuropathy Caused by Chlorfenapyr Poisoning (클로르페나피르 음독 후 발생한 독성 시신경병증 1예)

  • Park, Su Jin;Jung, Jae Uk;Kang, Yong Koo;Chun, Bo Young;Son, Byeong Jae
    • Journal of The Korean Ophthalmological Society
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    • v.59 no.11
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    • pp.1097-1102
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    • 2018
  • Purpose: To report a case of toxic optic neuropathy caused by chlorfenapyr ingestion accompanied by central nervous system involvement. Case summary: A 44-year-old female visited our clinic complaining of reduced visual acuity in both eyes for 7 days. She had ingested a mouthful of chlorfenapyr for a suicide attempt 2 weeks prior to the visit. Gastric lavage was performed immediately after ingestion at the other hospital. Her best-corrected visual acuity was finger count 30 cm in the right eye and hand motion in the left eye. Both pupils were dilated by 5.0 mm and the response to light was sluggish in both eyes. A relative afferent pupillary defect was detected in her left eye. Funduscopy revealed optic disc swelling in both eyes. Magnetic resonance imaging of the brain showed a symmetric hyper-intense signal in the white matter tract including the internal capsule, corpus callosum, middle cerebellar peduncle, and brainstem. The patient was diagnosed with toxic optic neuropathy induced by chlorfenapyr ingestion, and underwent high-dose intravenous corticosteroid pulse therapy. Three days later, the best-corrected visual acuity was no light perception in both eyes. Three months later, optic atrophy was observed in both eyes. Optical coherence tomography revealed a reduction in the thicknesses of the retinal nerve fiber layer and ganglion cell and inner plexiform layer in the macular area. Conclusions: Ingestion of even a small amount of chlorfenapyr can cause severe optic nerve damage through the latent period, despite prompt lavage and high-dose steroid treatment.

A Case study analysing the users of archives through web analytics (웹애널리틱스를 이용한 아카이브 이용자 분석 사례 연구)

  • Lee, Hyoeun;Yim, Jin Hee
    • The Korean Journal of Archival Studies
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    • no.45
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    • pp.83-120
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    • 2015
  • Record Information Services is an aggressive action of connecting documentaries focusing on the information needs of user. However, recent studies on the parliament's written information service recognize the necessity that it should segment the user's information requests, and provide personalized service, but have not discussed for specific cases or measures. While the importance of Web services written with the proliferation of information and popularization of the Web is emerging right to know but, it is not being performed properly by lack of sufficient manpower and budget along with lack of recognition in hands-on sites upon the user analysis. So, while increasing the efficiency of the hands-on workers of Record Information Services, the introduction of analytical tools that can be utilized in low budget agencies is needed. Web analytics is to analyze the behavior by analyzing Web logs which web users have left you visit the site. To estimate the behavior they want to request information of the analyzed Web user aims to provide a Web service, the Web service further continued improvement. There are several types that include among them Google Analytics offering a variety of analysis items for free and all over the world, many people are already using. This study introduces a Google Analytics web analytics focused and proposes a service improvement plan with specific web user segmentation analyzes the cases of Korea Democracy Foundation of Open Archives introduces them to the actual institutions.

The Study on Service Design Development for Pharmacy Users: Using Smart Phone Application

  • Lee, Dong-Min;Park, Hye-Jung;Lee, Dong-In
    • Journal of the Ergonomics Society of Korea
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    • v.31 no.1
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    • pp.93-100
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    • 2012
  • Objective: This study is to review the current state of services offered to pharmacy users, and develop a service design converging a prescription service and a smart phone application service in order to enhance patients' experience at pharmacies and home. Background: Under the new medical system; separation of prescribing and dispensing drugs, a doctor writes a prescription to their patients and patients have their prescription filled at the pharmacy. As the number of flue, allergy and atopy patients has increased, waiting lines have been longer at pharmacies. Besides, the current medical service system lacks of providing proper information on prescribed pills to patients. There are already services offered during waiting times such as offering free drinks, magazines or suggesting general drugs which you can buy without prescription, however they neither cover the current medical service's shorts nor shorten the waiting time. Method: I researched objective and perceived waiting times reduction methods, the current service status at pharmacies, and the government's policy direction in a medical service. Also, I observed a patient's journey from the hospital to pharmacy and then home. I examined the circumstance at pharmacies, patients' behaviors and their thoughts during their journey, and extracted three main goals to design a service in order to help patients have positive perception during the waiting time; (1) to reduce the perceived time by the way of visualizing time and offering readings about what patients consider necessary, (2) to educate patients what they are into and how to get through, (3) to establish trust among patients, doctors and pharmacists. Based on three goals, I designed a structure and a wireframe for a new service application of smart phones. Results: With a new service design for pharmacy users, users can track their medical record and visit the information about their current medical treatments anytime. Also the service helps patients build reliable relationships with doctors and pharmacists. Conclusion: Experience is not just an activity but series of multiple activities. The serving range of a medical service should not be determined by stakeholders but user's holistic experience. By approaching a service design with a holistic vision, it can enrich not only a temporary experience but also a whole life well being. Application: Since there are already many service applications advising patients about their illness and finding right doctors, this service design is focused on the experience from getting a prescription till feeling better. The next move is to combine those two parts medical services and design an integrated service application. As a prescription is going to be coded in numbers, we might consider to design an un-attended pharmacy which can shorten huge amount of time for filling prescriptions.

The Clinical Study on Far Diatance Spectacles for Teen-age and Twenty-age (10대와 20대의 원용안경에 관한 임상적 연구)

  • Hong, Soo-Hak;Kim, Sang-Kun;Seong, Jeong-Sub
    • Journal of Korean Ophthalmic Optics Society
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    • v.7 no.2
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    • pp.149-154
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    • 2002
  • This study is examined the difference between binocular spherical diopter and astigmatism diopter, spherical diopter, astigmatism diopter, and axis of astigmatism by sex and age with reference to the prescription of refraction for a total of 257 persons, 134 persons (male:78, female: 56)of teen-age and 123 persons of twenty-age who visit optical shop. Spherical correction diopter is mainly distributed to 280 eyes between -0.25D and -4.00D. And in astigmatism correction, for right astigmatism, 48 eyes(49.48%) are prescribed astigmatism diopter for a range of C-0.25~C-0.50D, 29 eyes(29.89%) has C-0.75~C-1.00D, 65 eyes(67.01%) has with the rule astigmatism. For left astigmatism, 43 eyes(42.57%) are prescribed astigmatism diopter of C-0.25~C-0.50D and 37 eyes(36.63%) has C-0.75C~1.00D, 73 eyes(72.27%) are shown with the rule astigmatism. And also each 108 persons(47.16%) and 28 persons(25.00%) are shown no difference between binocular spherical correction diopter and binocular astigmatism correction diopter, 94 eyes(39.49%) of teen-age and 104 eyes(42.27%) of twenty-age, male 119 eyes(41.90%) and female 79 eyes(34.34%) need correcting astigmatism. In pupillary distance, 165 persons mostly have 59~64mm.

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Survey of health status for preschool children who visit a public health center (일개 군 보건소 방문 미취학 아동의 건강 실태 조사)

  • Jo, Heui-Sug;Wie, Myung-Tack;Im, Jung-Nam;Kwak, Jung-Ok;Park, Hye-Sook;Ha, Eun-Hee;Wie, Cha-Hyung;Kang, Ji-Yong
    • Journal of agricultural medicine and community health
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    • v.22 no.1
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    • pp.19-26
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    • 1997
  • The purpose of this study was to analyze the physical development and health status of 5 year-old children for more effective health management of preschool children. This study carried out examinations of height, weight, hemoglobin, visual acuity & dental examination for 5 years-old preschool children in Kwang-ju up, Kwang-ju gun, Kyunggi-Do from January to February, 1996. For height and weight, the data were compared with the 1985's Korean standard and the hemoglobin and visual acuity data were compared with the Korean standard. The results were as follows. The average height for 5 year-old male children was 106.3${\pm}$4.7(cm) and that of 5 year-old female children was 105.3${\pm}$4.3(cm). Sixty seven point eight percent of male subjects registered below the 50th percentile for the Korean standard height and 79.5% of the female subjects registered below the 50th percentile for female. The average weight for 5 year-old children was 18.6${\pm}$2.6(kg) for females. Also, it is estimated that obese subjects totaled 2.7%. For the visual acuity, 18.0% of subjects had weak vision in the left eye and 16.9% in the right eye. As a result, it was advised that these children undergo further examination. It was remarkable that there were so many anemic children. Children with a hemoglobin content of less than 11.9(g/dl) totaled 47.8%. It is anticipated that the results of this study will contribute to the on-going evaluation and subsequent planning for the children health management program within the health promotion program of public health center in Kwang-ju gun.

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A Statistical Study of the Foreign Bodies in the Air Passages (기도 이물의 임상통계적 고찰)

  • 신기철;이동명;김진영;김홍기
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1981.05a
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    • pp.4.1-4
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    • 1981
  • The statistical study was done on 74 cases of foreign bodies in the air passages, who visited the department of otolaryngology of SNUH during recent 5 years from 1975 to 1980. The result was as follows, 1) Of the total 74 cases, 55 cases were male and 18 cases were female. The ratio between male and female was 3 : 1. 41.8% of all-cases were under 2 years of age, 75.5% were under 3 years, and 83.6% were under 5 years. 2) Major symptoms on visit were dyspnea, cough, cyanosis. No significant symptoms was noted in 6.7%. Initial physical findings were coarse breathing sound, decreased breathing sound, and stridor. No abnormal physical findings were noted in 10.8%. 3) 48.6% of total cases visited hospital within 24 hours. There was one case who visited hospital over 2 years later. 4) Initial simple chest film showed atelectasis in 25.0%, emphysema in 32.8%, definite foreign body shadow in 17.2% and within normal limit in 17.2%. 5) 60.8% of total cases were vegetables, 15.5% were metals, 16.2% were fish bone, and 2.7 % were others. 6) Vegetables were most frequent foreign bodies in the cases under 5 years of age. 7) 40.5% of total cases were lodged in the right main bronchus, 31.0% were in the left main bronchus, 9.8% were in trachea and 6.7% were in multiple sites, 8) Foreign bodies were removed by ventilating bronchoscopy in 82.3%, by tracheostomy only in 2.7%, by tracheal suction in 2.7%, by spontaneous removal in 1.3%, by thorachotomy in 5.4% and 5.4% of total cases were expired.

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Preparatory Research prior to the Development of Consumer-Tailored 3D Printing Service Platform (소비자 맞춤형 삼차원 프린팅 서비스 플랫폼 개발을 위한 탐색)

  • Lee, Guk-Hee;Choi, Hye-Kyong
    • Science of Emotion and Sensibility
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    • v.20 no.1
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    • pp.3-16
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    • 2017
  • With the development and proliferation of three-dimensional(3D) printers, consumers in modern society can now print products of what they want three-dimensionally at home. However, consumers themselves would have to produce digital design maps that are compatible with 3D printers and to set up the optimum printing quality and temperature, as well as to pay for maintenance and repair of 3D printers and to respond to any possible lawsuits related to intellectual property right about designs in order to make possible consumer-tailored manufacturing through 3D printing. However, in reality, since it is very difficult for consumers to respond to these issues, it is necessary to develop services that perform 3D printing on behalf of consumers in the desired direction. Motivated by this objective, this study investigated user experiences on Shapeways(www.shapeways.com), which is a global online 3D printing product and sales companies, from many viewpoints in order to obtain insight into 3D printing services and modes which were preferred by consumers. The study result showed that quantitative evaluations on usability, search process, price adequacy, re-visit intention, diversity of design, and satisfaction of design was scored low overall. Furthermore, this study acquired insight about consumer-tailored 3D printing services through constructive suggestions on multi-language support, openness of manufacturing process, simultaneous operation of online and offline sites, design-oriented consumer-tailored manufacturing service, services that ensure delivery safety and product durability, and surface finishing services. This study is expected to provide a wide range of opinions not only on 3D printing service platform development but also on related industry and research.