• 대한상한금궤의학회지
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• v.5 no.1
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• pp.75-84
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• 2013

Objective : This case report evaluated the effect of Saengkangsasim-tang(生薑瀉心湯) on allergic rhinitis. Methods : Two different patients of allergic rhinitis were treated with Saengkangsasim-tang (生薑瀉心湯) in accordance with diagnostic system based on Shanghanlun(傷寒論) six meridian patterns and provisions. Results : After a series of Saengkangsasim-tang treatments, the symptoms of allergic rhinitis patients improved in 2 cases. Conclusions : According to diagnostic system based on Shanghanlun(傷寒論) six meridian patterns and provisions, this case study shows that Saengkangsasim-tang is effective on allergic rhinitis. However further clinical studies in depth are needed.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.22 no.2
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• pp.251-260
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• 2009

Objective : This study is to investigate the effect of 8 Constitution Acupuncture on allergic rhinitis patients Methods : We treated 3 allergic rhinitis patients diagnosed as Colonotonia with 8 Constitution Acupuncture by dry needle. The degree of improvement was evaluated by Visual Analogue Scale(VAS) Results & Conclusions : After taking 8 Constitution Acupuncture sessions, the symptoms of allergic rhinitis was improved. After 8 Constitution Diet, the effect of therapy was lingered. This study shows that the allergic rhinitis can possibly be treated not only with herb medicine, but also with acupuncture and diet.

• Journal of Intelligence and Information Systems
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• v.1 no.1
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• pp.91-109
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• 1995

This paper compared four knowledge acquisition methods (namely, neural network, case-based reasoning, discriminant analysis, and covariance structure modeling) for allergic rhinitis. The data were collected from 444 patients with suspected allergic rhinitis who visited the Otorlaryngology Deduring 1991-1993. Among four knowledge acquisition methods, the discriminant model had the best overall diagnostic capability (78%) and the neural network had slightly lower rate(76%). This may be explained by the fact that neural network is essentially non-linear discriminant model. The discriminant model was also most accurate in predicting allergic rhinitis (88%). On the other hand, the CSM had the lowest overall accuracy rate (44%) perhaps due to smaller input data set. However, it was most accuate in predicting non-allergic rhinitis (82%).

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.4
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• pp.151-161
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• 2019

Objectives : This report was performed to observe the effects of bloodletting therapy on the rhinitis patients. Methods : 2 patients with rhinitis were treated by bloodletting therapy. We evaluated the pre-and post-treatment symptoms by NRS(numbering rating scale) and TNSS(total nasal symptom score). Results : After treatment, the symptoms of rhinitis and NRS were decreased and TNSS was improved. Conclusions : Bloodletting therapy in nasal cavity is effective to Rinitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.15 no.2
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• pp.145-155
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• 2002

Allergic Rhinitis is specified by three symptoms such as sternutation, rhinorrhea and rhinanchon. Besides these three major symptoms, it is characterized by sternutation, frontal headache, photophobia and epiphora. The allergic rhinitis occurs when inhaled allergen is in contact with nasal mucosa, which causes immune response. And Tonguetangmi is one of the most frequently used medical treatment for the allergic rhinitis. A study on the 20 patients with allergic rhinitis who took Tonguetangmi a year ago shows that the oral medication for 10 days of Tonguetangmi for an adult who has allergic rhinitis less than one year results in the best efficiency of the remedy.

• 대한상한금궤의학회지
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• v.13 no.1
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• pp.189-196
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• 2021

Objective : This study aimed to report the improvement of a patient with chronic rhinitis treated with herbal medication using the disease pattern identification diagnostic system (DPIDS) based on the Shanghanlun provisions. Methods : According to the Shanghanlun DPIDS and an etymological interpretation of Chinese characters, the patient was diagnosed with Reverting yin disease (provision 352) and took Dangguisayeokgaosuyusaengang-tang herbal medication for 50 days. The change in symptoms of chronic rhinitis were estimated using the Total Nasal Symptom Score (TNSS), the Rhinitis Control Assessment Test (RCAT), and a visual analog scale (VAS). Results : The TNSS score decreased from 8 to 3, the RCAT score decreased from 14 to 24, and the VAS decreased from 10 to 2. Conclusions : The main causes of the disease were 厥 and 內. This is the first case report of describing the treatment of chronic rhinitis with Dangguisayeokgaosuyusaengang-tang.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2011.11a
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• pp.23-24
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• 2011

• Clinical and Experimental Pediatrics
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• v.49 no.6
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• pp.593-601
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• 2006

Allergic rhinitis is a common disease of childhood characterized by nasal, throat, and ocular itching, rhinorrhea, sneezing, nasal congestion. Those affected with allergic rhinitis often suffer from associated inflammatory conditions of the mucosa, such as allergic conjunctivitis, rhinosinusitis, asthma, otitis media with effusion, and other atopic conditions, such as eczema and food allergies. Allergic rhinitis must be diagnosed and treated properly to prevent complications and impaired quality of life. Despite a high prevalence, allergic rhinitis isoften undiagnosed and inadequately treated, especially in the pediatric population. The first step in treatment is environmental control when appropriate. It may be difficult to eliminate all offending allergens effectively to reduce symptoms, so medications are often required. Many different classes of medications are now available, and they have been shown to be effective and safe in a large number of well-designed, clinical trials. Antihistamines are effective in treating immediate symptoms of sneezing, pruritus, watery eyes, and rhinorrhea. Second generation antihistamines are the preferred antihistamines because of their superior side effect profile. Thus, decongestants are commonly used with oral antihistamines. Intranasal corticosteroids are the most effective therapy for allergic rhinitis. Leukotriene modifier may be as effective as antihistamines in treating allergic rhinitis symptoms. Cromolyn sodium is an option for mild disease when used prophylactically, and ipratropium bromide is effective when rhinorrhea is the predominant symptom. When avoidance measures and medications are not effective, specific immunotherapy is an effective alternative. Only immunotherapy results in sustained changes in the immune system. Because of improved understanding of the pathogenesis, new and better therapies may be forthcoming. The effective treatment of allergic rhinitis in children will reduce symptoms and will improve overall health and quality of life, making a happier, healthier child.

• The Journal of Pediatrics of Korean Medicine
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• v.32 no.1
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• pp.19-29
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• 2018

Objectives This study investigated the effects of Cheongyeonsan for allergic rhinitis. Methods First, the GS/MS was used to analyze the effects of Cheongyeonsan by measuring inflammatory markers. Second, 3 groups of 10 6-week-old BALB/c mice were divided into Ctrl (no treatment), ARE (allergic rhinitis-induced without treatment), and CRT (allergic rhinitis-induced after Cheongyeonsan treatment) groups. Ovalbumin (OVA) was used as an antigen to induce allergic rhinitis and sensitization was performed by intraperitoneal injection of 0.1% OVA solution 21, 14, and 7 days before the onset of allergic rhinitis. Allergic rhinitis was induced by dropping OVA solution on the nasal cavity of each mouse for 5 days after the last sensitization. Seven days after the first induction, second induction was introduced by the same method. After making the section, MMP-9, substance P, $TNF-{\alpha}$, $NF-{\kappa}B$ p65, COX-2, iNOS and Nrf, apoptotic cells were observed by Masson trichrome staining, immunohistochemical staining, TUNEL of nasal mucosal tissues of each group. Results GC/MS results showed undecanoic acid. Masson trichrome results showed that the CRT group had less respiratory epithelial damage. Immunohistochemical staining showed CRT group had 58% decrease in MMP-9, 61% decrease in substance P, 55% decrease in $TNF-{\alpha}$, 38% decrease in $NF-{\kappa}B$ p65, 53% decrease in COX-2, 54% decrease in iNOS, 87% increase in Nrf compared to those of the ARE group. TUNEL showed a positive reaction of 84% increase in apoptotic cells greater than that of the ARE group. Conclusions Cheongyeonsan alleviates nasal mucosal damage and reduces inflammatory mediators from allergic rhinitis-induced mice.

• Journal of Physiology & Pathology in Korean Medicine
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• v.33 no.2
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• pp.116-122
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• 2019

The aim of this study is to evaluate the anti-inflammatory effect of Hataedock treatment using Coptidis Rhizome and Glycyrrhiza Uralensis (CG) mixed extract in allergic rhinitis induced NC/Nga mice. We divided NC/Nga mice into 3 groups as follows; allergic rhinitis-induced group after CG Hataedock treatment (CGT, n=10), no treatment group (Ctrl), allergic rhinitis elicited group (ARE). To induce allergic rhinitis, NC/Nga mice of 3 weeks age were sensitized on 7, 8 and 9week by Ovalbumin (OVA) antigen in intranasal space. Hataedock using CG extract was administered on week 3 in allergic rhinitis-induced group (CGT) after Hataedock treatment. To identify distribution of Interlukin (IL)-4, Cluster of differentiation 40 (CD40), high-affinity IgE receptor ($Fc{\varepsilon}RI$), substance P, Matrix metallopeptidase 9 (MMP-9), Nuclear $factor-{\kappa}B$ ($NF-{\kappa}B$) p65, Inducible nitric oxide synthase (iNOS) and Cycloxygenase-2 (COX-2), we used histological examination. CGT significantly inhibited IL-4 and CD40 response compared with ARE. The reduction of Th2 cytokine expression decreased inflammatory mediators such as $Fc{\varepsilon}RI$, substance P, MMP-9, $NF-{\kappa}B$ p65, iNOS and COX-2. Such immunological improvement induced reduction of respiratory epithelial damage and mucin secretion in goblet cell. These results indicate that Hataedock treatment suppresses allergic rhinitis through modulating of Th2 responses and diminishing various inflammatory mediators in nasal mucosal tissue. It might have potential applications for prevention and treatment of allergic rhinitis.