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Effect of Exercise Training following Hypokinesia on the Length and Circumference of Atrophied Soleus and Plantaris Muscle in Rats (활동저하후 회복기의 운동훈련이 쥐의 위축근의 길이와 둘레에 미치는 영향)

  • 최명애;안숙희
    • Journal of Korean Academy of Nursing
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    • v.22 no.3
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    • pp.325-336
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    • 1992
  • The purpose of this study was to determine the effect of exercise training on the length and circumference of atrophied muscles to see whether improvement in restoring the atrophied muscle mass, of either length or circumference growth could be induced through exercise training. Adult female Wistar rats were maintained for 14 days with hindlimb suspension. Rats were then assigned randomly to a sedentary group or training group. The length and circumference of both atrophied soleus and plantaris muscle for the training and sedentary groups following hindlimb suspension were compared with those of a control group. Length and circumference of both atrophied soleus and plantaris muscle in trained group was compared with those in the sedentary group. The results can be summarized as follows ; 1) Atrophy of soleus and plantaris muscle was induced with hindlimb suspension. 2) The circumference of both the soleus and plantaris muscle following hindlimb suspension was reduced to 51. 72%, 66.67% respectively compared to the control group. The length of both the soleus and plantaris muscle following hindlimb suspension did not show any difference compared to the control group. 3) There was no difference in length for either the atrophied soleus or plantaris muscle between the trained and the sedentary group during recovery from hindlimb suspension. 4) The circumference of both the atrophied soleus and plantaris muscle did not return to normal in the sedentary group, however, the circumference of both the atrophied soleus and plantaris muscle were significantly greater than of the control in the trained group, 14.22% and 9.38% respectively. 5) The circumference of both the atrophied soleus and plantaris muscle in the trained group was significantly larger than that of both muscles in the sedentary group at day 28 of recovery. From these results, it can be suggested that improvement in restoring the atrophied muscle mass through exercise training might be induced by growth of the muscle circumference.

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Architectural Embodiment of National Identity: Finnish National Romanticism around 1900 (민족 정체성의 건축적 구현: 1900년 전후의 핀란드 민족낭만주의 건축에 관한 고찰)

  • Kim, Hyon-Sob
    • Journal of architectural history
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    • v.14 no.4 s.44
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    • pp.59-72
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    • 2005
  • Architectural embodiment of a national identity has long been a significant topic in Korean architectural circles. For this reason, it must be helpful to examine the so-called, 'National Romanticism' of Finnish architecture around 1900 in that Finnish architects of the time struggled to embody their national identity through their projects. Considering the historical and linguistic affinities between Finland and Korea, the Finnish architectural situation draws . our additional attention. This paper aims at showing its historical background, the meaning of each type of buildings in the stream, and limitations it implies. The atmosphere of Finnish nationalist movement, which was provoked by [Kalevala] publications (1835; 1845) and shown in Karelianism, was heightened by Tsarist Empire's Russification programme of Finland in the late 19th century Architecture was one of the most important genres expressing her national identity. Finnish national romantic architecture could be divided into three. The first is a log house style for artists' studio house, motivated by the Finnish vernacular farmstead - especially by Karelian farmhouse. This type of building signifies the Finns' will to return to their motherly soil. The second is a stone architecture style for public buildings, inspired by Finnish church or castle of an early medieval time. By using roughly-cut granite as the main exterior material, buildings of this type symbolise the toughness of legendary heroes and Finns' desire for national Independence. The third type of building was based on both of the former or more dependent on architects' Imagination and creativity. However, Finnish national romantic architecture has been criticised by some critics owing to its decorative, eclectic and self-indulgent characteristics. Probably, it was not really national but rather inter-national because of the Influences of English Arts and Crafts Movement, the American Richardsonian architecture and the continental Art Nouveau. And the negative images of 'national' and 'romantic' made some historians coin other terms like 'national realism' or 'material realism'. As another limitation, one raises the low degree of its contribution to the entire architectural history. Despite these criticisms, however, this paper argues that Finnish national romantic architecture is meaningful in itself, particularly because it illustrates vividly Finns' struggle to search for their national identity and, after all, their craving for national independence.

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Case Studies on Preparing a Business Plan for the Foundation of Food Service Business and Analysis of Investing Economy. (외식사업 신규창업을 위한 사업계획서 작성방법 사례와 투자경제성 분석에 관한 연구)

  • 홍기운
    • Culinary science and hospitality research
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    • v.3
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    • pp.385-421
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    • 1997
  • This study was performed as placing stress on business plan preparation and investing economy analysis centered to cases upon presenting the premises of study for new foundation of food service business. The summarized results are as follows: 1. In the aspect of carrying out process of practical project, establishing the promotion strategy, the facility project program, the menu program, the facility and furniture program, organization & manning schedule, the business operation schedule, review of all laws & provisions and the allout promotion schedule in order were deployed. 2. Analysis of investing economy for review of profitability 1) In case of investment, excluding 600million for the real setate lease among the total investment of 1billion, it was required by 161, 235, 000 for interior project, 161, 110, 000 for facility & equipment, 19, 235, 000 for fittings, 27, 600, 000 for menu plate & uniform, 27, 600, 000 for furniture, 13, 800, 000 for sign article. 2) In case of loss & profit presumed the annual turnover is to be 1, 115, 856, 000 the contigent profit(before tax) is to be 148, 966, 000 which is 13.3% in comparson to the sales amount and the net profit(after tax) for this term s to be 104, 276, 000 which is 9.3% against the sales and the profitable ratio to the equity investment( 500 million) is 20.9% and it satisfies 20% of the premises of study. 3) In case of the payback period will be approximately two(2) years which indicated within three(3) years that is standard of new project evaluation term of ordinary enterprise. 4) In case of internal rate of return it will be 21.5% which is favorable profitability as taking into account of 15% that is standard of new project evaluation by ordinary enterprise based on general downtown money interest. That the investing value of Happy Day profitability is hinted as it is sufficient enough as the case under this study based upon such results and considered that securing supremacy is competitive power in case of commitment will be possible.

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THE EFFECTS OF NICOTINE ON HUMAN GINGIVAL FIBROBLAST & PERIODONTAL LIGAMENT CELLS IN VITRO (니코틴이 배양인체 치은섬유모세포 및 치주인대세포의 활성에 미치는 효과)

  • Kong, Young-Hwan;Yoo, Hyung-Keun;Shin, Hyung-Shik
    • Journal of Periodontal and Implant Science
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    • v.25 no.2
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    • pp.181-191
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    • 1995
  • The ability of fibroblasts attach to teeth is of paramount imporance in re-establishing the lost connective tissue attachment after periodontal therapy. Tobacco contains a complex mixture of substances including nicotine. various nitrousamines, trace elements. and a variety of poorly characterized substances. The effects of nicotine on fibroblasts have reported an altered morphology and attachment of fibroblasts to substrates and disturbances in protein synthesis and secretion. This study examined the effect of nicotine, a major component of the particulate phase of tobacco smoke, on human gingival fibroblasts and periodontal ligament cells attachment to tissue culture surfaces and cellular activity of human gingival fibroblasts and periodontal ligament cells. Pooled human gingival fibroblasts made from extraction of 3rd molar were utilized between passage 4 and 5 and plated in 96 well plate at 20,000 cells per well. Cell number were determined using 3-(4,5-dimethylthiazole-2-y)2,5-diphenyltetrazolium bromide(MTI) , which is reflection of mitochondrial dehydrogenase activity. The concentration of nicotine used were 0.025, 0.05, 0.1, 0.2 and $0.4{\mu}M$, the average serum concentration for a smoker being approximately $0.1{\mu}M$. The results were as follows : 1. Attachment effects of nicotine on human gingival fibroblasts and periodontal ligament cells Excepts of $0.4{\mu}M$, the effects on attachment with increasing numbers of cells attaching with increasing nicotine concentrations, compared to control group. But over the 60min, return to control value. 2. The effect of cellular activity on human gingival fibroblasts and periodontal ligament cells. The cellular activity of human gingival fibroblasts and periodontal ligament cells were similar or decrease to control value at 1st incubation day. At 2nd incubation day, 0.05, 0.1, 0.2, $0.4{\mu}M$ concentrations were statistically different from control value on gingival fibroblasts group. But at 3rd incubation day, cellular activities of all experimental group were significantly decrease than control group.

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THE EFFECTS OF FIBRONECTIN & GROWTH FACTOR ALONE OR COMBINED APPLICATION ON THE ACTIVITY OF GHUMAN GINGIVAL FIBROBLASTS AND PERIODONTAL LIGAMENT CELLS (Fibronectin과 성장인자의 단독 혹은 복합투여가 배양 인체 치은섬유모세포 및 치은인대세포의 활성에 미치는 효과)

  • Kim, Eung-Tae;Han, Du-Seok;Yoo, Hyung-Keun;Shin, Hyung-Shik
    • Journal of Periodontal and Implant Science
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    • v.25 no.2
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    • pp.239-251
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    • 1995
  • The selective migration, attachment and proliferation of periodontal ligament cells are the desired goal of periodontal regeneration therapy. Fibronectin is well known for an attachment protein for dentin surface. Also, Fibroblast growth factor (FGF) is well known to enhance the periodontal regeneration. The purpose of this study was to evaluation the effect of fibronection and FGF on the attachment rate and the cellular activity. Human gingival fibroblast and periodontal ligament cells were cultured from the teeth extracted for non-periodontal reson. Cultured human gingival fibroblast and periodontal ligament cells in vitro were treated with fibronectin and FGF a various dosage and culture times. Cellular activity was examined by MTT assay. The results of this study was demonstrated that cell attachment rate of experimental group was under the control value at 1st, 2nd, 3rd incubation day. But, at 3rd incubation day, attchment value tended to return to the control value. In case of fibronectin alone application, cellular activity was decreased than that of control at 1st, 2nd incubation day. But 3rd day, cellular activity was returned to the control value. The activity of gingival fibroblast in FGF alone application was decreased thatn that of control at each incubation day. But activity of periodontal cell group was increased cell activities at 2nd, 3rd day. Additionally cellular activity of fibronectin & FGF combined application on gingival fibroblast group was similar to control value at incubation day. But activity of periodontal ligament cell group was increased at 2nd, 3rd day compared with control group.This study demonstrated that combined application of fibronectin & FGF induced the selective chemotaxis for periodontal ligament cell in vitro.

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A Study on Customer Response for the Hotel & Food Service Industry by Mood of Background Music (호텔.외식산업 배경음악의 무드에 따른 고객 반응에 관한 연구)

  • Cho, Soo-Hyun
    • Culinary science and hospitality research
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    • v.16 no.3
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    • pp.114-129
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    • 2010
  • The purpose of this study is the suggestion of tempos and genres to make a effective mood in a hotel and restaurant. As a result of this study, it was verified which genre and tempo is the most effective at each case of various restaurant. The result of this study shows that the genres and tempos of background music effect to a mood of customer, and a satisfaction related to a return visit and a recommendation. This paper offer a useful method when a manager want to change a ambience of business place. For example, a manager will be able to choose a change of background music instead of remodeling requiring much money. At the other case, a manager will be able to maximize a expression effect of business concept as following the suggestion of this study. This thesis suggests how a managers can simultaneously achieve a customer's satisfaction and a financial benefit by selection of music.

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Correlation between Unfavorable Split in the Distal Segment during the Bilateral Sagittal Ramus Osteotomy and Skeletal Relapse: Cone-Beam Computed Tomography Study

  • Kim, Young-Hoon;Lee, Baeksoo;Kwon, Yong-Dae;Ohe, Joo-Young;Lee, Jung-Woo;Jung, Junho;Lee, Seok Mo;Choi, Byung-Joon
    • Journal of Korean Dental Science
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    • v.14 no.2
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    • pp.110-117
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    • 2021
  • Purpose: The purpose of this article is to study the relationship of unintentionally extended split in the distal segment during the bilateral sagittal split ramus osteotomy (BSSRO) and skeletal relapse. Materials and Methods: Twenty patients with mandibular prognathism were divided into two groups according to whether or not unintentionally extended split had occurred. Cone-beam computed tomography images were taken before surgery (T0), immediately after surgery (T1), and postoperatively at 6 months (T2). The stability was evaluated by measuring the change of Nasion perpendicular-Pogonion (N-Pog) distance. Result: Both groups showed mild advancement of Pog during follow-up. In both groups, the condyle head rotated inward and moved posterioinferiorly after surgery, but tended to return to their original position during follow-up. Conclusion: There was no statistically significant difference between the two groups in mandible position. Moreover, the condylar position was stable. If it is difficult to proceed reduction of the unintentionally extended split, careful inspection should be performed to prevent subsequent complications during follow-up.

Effects of Early Oral Feeding versus Delayed Oral Feeding on Bowel Function, Gastrointestinal Complications and Surgical Recovery after Cesarean Section under Regional Anesthesia: Systematic Review and Meta-Analysis (부위마취로 제왕절개 수술을 받은 산모의 조기 경구섭취가 장 기능, 위장관 합병증 및 수술 후 회복에 미치는 효과: 체계적 문헌고찰 및 메타분석)

  • Kim, HyoJin;Jeon, YeongKyung;Yoon, SoYoung;Lee, GeumMoon
    • Journal of Korean Academy of Nursing
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    • v.51 no.6
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    • pp.732-745
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    • 2021
  • Purpose: This study aimed to assess combined effects of early oral feeding after Cesarean section (C/S) under regional anesthesia on bowel function, gastrointestinal complications and surgical recovery. Methods: A systematic literature search was conducted using KISS, RISS, PubMed, CINAHL, EMBASE, CENTRAL and Google Scholar to identify randomized clinical trials comparing early oral feeding (EOF) with delayed oral feeding (DOF) after C/S. Outcome variables were bowel function and gastrointestinal complications and surgical recovery. Effect size was calculated using weighted mean differences (WMDs) and relative risks (RRs), with 95% confidence intervals (CIs). Results: Seven studies involving 1,911 patients from 568 studies, 7 studies were included in meta-analysis. EOF was significantly associated with shorter time to recover bowel movement compared with DOF (WMD, - 2.50; CI, - 3.50~- 1.50). EOF was not associated with nausea (RR, 1.15; CI, 0.87~1.53) and vomiting (RR, 0.96; CI, 0.65~1.42), but lower incidence of abdominal distension (RR, 0.70; CI, 0.50~0.98). EOF was significantly associated with shorter time to discontinuation of intravenous fluids (WMD, - 8.88; 95% CI, - 16.65~- 1.11) and removal of urinary catheter (WMD, - 15.23; CI, - 25.62~- 4.85). Conclusion: This meta-analysis provides evidence that EOF after C/S under regional anesthesia not only accelerates return of bowel function and surgical recovery but also reduces gastrointestinal complications. These results suggest that EOF should be offered to women who have undergone C/S to improve the recovery experience and reduce overall medical costs.

Differential gene expression profiles of periodontal soft tissue from rat teeth after immediate and delayed replantation: a pilot study

  • Chae, Yong Kwon;Shin, Seo Young;Kang, Sang Wook;Choi, Sung Chul;Nam, Ok Hyung
    • Journal of Periodontal and Implant Science
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    • v.52 no.2
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    • pp.127-140
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    • 2022
  • Purpose: In dental avulsion, delayed replantation usually has an uncertain prognosis. After tooth replantation, complex inflammatory responses promote a return to periodontal tissue homeostasis. Various types of cytokines are produced in the inflammatory microenvironment, and these cytokines determine the periodontal tissue response. This study aimed to identify the gene expression profiles of replanted teeth and evaluate the functional differences between immediate and delayed replantation. Methods: Maxillary molars from Sprague-Dawley rats were extracted, exposed to a dry environment, and then replanted. The animals were divided into 2 groups according to the extra-oral time: immediate replantation (dry for 5 minutes) and delayed replantation (dry for 60 minutes). Either 3 or 7 days after replantation, the animals were sacrificed. Periodontal soft tissues were harvested for mRNA sequencing. Hallmark gene set enrichment analysis was performed to predict the function of gene-gene interactions. The normalized enrichment score (NES) was calculated to determine functional differences. Results: The hallmark gene sets enriched in delayed replantation at 3 days were oxidative phosphorylation (NES=2.82, Q<0.001) and tumor necrosis factor-alpha (TNF-α) signaling via the nuclear factor kappa light chain enhancer of activated B cells (NF-κB) pathway (NES=1.52, Q=0.034). At 7 days after delayed replantation, TNF-α signaling via the NF-κB pathway (NES=-1.82, Q=0.002), angiogenesis (NES=-1.66, Q=0.01), and the transforming growth factor-beta signaling pathway (NES=-1.46, Q=0.051) were negatively highlighted. Conclusions: Differentially expressed gene profiles were significantly different between immediate and delayed replantation. TNF-α signaling via the NF-κB pathway was marked during the healing process. However, the enrichment score of this pathway changed in a time-dependent manner between immediate and delayed replantation.

Social Capital Trends and the Relationship between Social Capital and COVID-19-Related Behaviors & Perceptions (시군구 수준의 사회자본 추이와 사회자본과 COVID-19 관련 행위와 인식 간의 관계)

  • Geun-Chan Lee
    • Health Policy and Management
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    • v.33 no.3
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    • pp.338-354
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    • 2023
  • Background: The influence of social capital on the spread of coronavirus disease 2019 (COVID-19) and related behaviors and perceptions has been recognized during the COVID-19 pandemic. This study aims to analyze the trends in social capital using primary data from the Korean Community Health Survey, which is the only available source in Korea for local-level social capital analysis. It also investigates the relationship between various variables, including social capital, as factors influencing COVID-19-related behaviors and perceptions. Methods: The study analyzed the temporal trends of social capital using raw data from four community health surveys conducted in 2017, 2019, 2020, and 2021. A multilevel analysis was conducted to examine the relationship between social capital and COVID-19-related behaviors and perceptions following the onset of the COVID-19 pandemic in 2020. Results: Social capital consists of trust, bonding social capital, and bridging social capital. Within the trust sub-factor, trust in neighbors (Trust-1) declined after the COVID-19 pandemic, whereas trust in safety and general environment (Trust-2) and trust in medical services and public transportation (Trust-3) increased. Additionally, the gap between municipalities narrowed. COVID-19-related behaviors and perceptions, such as adherence to COVID-19 prevention measures, return to normal activities, and fear of COVID-19, showed improvement in 2021 compared to the previous year. Individual-level trust in neighbors was associated with reduced fear of COVID-19, while community-level trust in neighbors was associated with increased fear of COVID-19. Conclusion: Social capital plays a role in mitigating public health crises, and it is necessary to implement active policies that address the gap in social capital between metropolitan and rural areas. Strengthening risk communication regarding emerging infectious diseases such as COVID-19 is crucial.