• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.1682-1685
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• 2005

System algorithms estimated by deterministic input may occur the error between predicted and actual output. Especially, actual system can't predict the exact outputs due to uncertainty and tolerance of input parameters. A single output to a set of inputs has a limited value without the variation. Hence, we should consider various scatters caused by the load assessment, material characteristics, stress analysis and manufacturing methods in order to perform the robust design or estimate the reliability of structure. The system design with uncertainty should perform the probabilistic structural optimization with the statistical response and the reliability. This method calculated the probability distributions of the characteristics such as stress by combining stress analysis, response surface methodology and Monte-Carlo Method and got the probabilistic sensitivity. The sensitivity of structural response with respect to inconstant design variables was estimated by fracture probability. Therefore, this paper proposed the probabilistic reliability design method for fracture of uncorved freight end beam and the design criteria by fracture probability.

• The Korean Journal of Applied Statistics
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• v.23 no.6
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• pp.1057-1065
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• 2010

In this paper we discuss some cautionary notes in using the Pearson chi-squared test statistic for the goodness-of-fit of the ordinal response model. If a model includes continuous type explanatory variables, the resulting table from the t of a model is not a regular one in the sense that the cell boundaries are not fixed but randomly determined by some other criteria. The chi-squared statistic from this kind of table does not have a limiting chi-square distribution in general and we need to be very cautious of the use of a chi-squared type goodness-of-t test. We also study the limiting distribution of the chi-squared type statistic for testing the goodness-of-t of cumulative logit models with ordinal responses. The regularity conditions necessary to the limiting distribution will be reformulated in the framework of the cumulative logit model by modifying those of Moore and Spruill (1975). Due to the complex limiting distribution, a parametric bootstrap testing procedure is a good alternative and we explained the suggested method through a practical example of an ordinal response dataset.

• Journal of Pharmacopuncture
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• v.11 no.2
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• pp.13-19
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• 2008

Objectives To investigate the therapeutic effects of intravenous cultivated wild ginseng(Panax ginseng C.A. Meyer) pharmacopuncture(CWGP) in treating patients with non-small cell lung cancer(NSCLC). Design Prospective case series. Setting This study was conducted at the East-West Cancer Center of Dunsan Oriental Hospital, Daejeon University. Patients Two non-small cell lung cancer patients. Intervention Two non-small cell lung cancer patients were injected CWGP(20mL/day) mixed with 0.9% normal saline(100mL) intravenously. Each patient received a total of 16 and 9 cycles, respectively. One cycle is composed of 14 days. Outcome Measures The effect of intravenous CWGP was measured by scanning with computed tomography(CT) after every 2 cycle and Positron emission tomography- computed tomography(PET/CT) after every 6 cycles. Response and progression was evaluated using the Response Evaluation Criteria in Solid Tumors(RECIST) Committee classification of complete response(CR), partial response(PR), progressive disease(PD) and stable disease(SD). Results They were treated with intravenous CWGP for 8 and 5 months respectively. time later, each tumor remains stable disease(SD). Conclusion These cases may give us a possibility that intravenous CWGP offers potential benefits for non-small cell lung cancer patients.

• Advances in Computational Design
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• v.1 no.1
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• pp.105-117
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• 2016

The objective of this work is to study the restraining effect in fire resistance of framed structures and to evaluate the global response of reinforced concrete frames when exposed to fire based on advanced finite element method. To study the response a single portal frame is analyzed. The effect of floor slab on this frame is studied by modeling a beam-column-slab assembly. The evolution of temperature distribution, internal stresses and deformations of the frame subjected to ISO 834 standard fire curve for both the frames are studied. The thermal and structural responses are evaluated and a comparison of results of individual members and entire structure is done. From the study it can be seen that restraining forces has significant influence on both stresses and deflection and overall response of the structure when compared to individual structural member. Among the various structural elements, columns are the critical members in fire and failure of column causes the failure of entire structure. The fire rating of various structural elements of the frame is determined by various failure criteria and is compared with IS456 2000 tabulated fire rating.

• The Journal of the Korea Contents Association
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• v.14 no.3
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• pp.463-469
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• 2014

Safety related devices unconstrained temporally in the process of operation of nuclear power plants could be damaged by the sliding during seismic activity. In this study sliding response of unconstrained objects to the base excitations is studied experimentally and analytically. In experiments static and dynamic tests to determine the coefficient of friction and the shaking table experiments to verify the sliding response of the analytic results were conducted. Numerical solutions by solving the nonlinear differential equations of motion governing sliding were found by the computer program using the step by step acceleration method. The exact solutions of the sliding response to the simple forms of base excitations were found to verify the computer program developed in this study. Relative displacement envelopes were suggested as a colliding criteria of the unconstrained objects.

• Journal of Korean Society for Quality Management
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• v.42 no.4
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• pp.685-700
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• 2014

Purpose: The purpose of this paper is to develop a systematic weighting procedure based on process capability indices method applying weighted mean squared error minimization (WMSE) approach to dual response surface optimization. Methods: The proposed procedure consists of 5 steps. Step 1 is to prepare the alternative vectors. Step 2 is to rank the vectors based on process capability indices in a pairwise manner. Step 3 is to transform the pairwise rankings into the inequalities between the corresponding WMSE values. Step 4 is to obtain the weight value by calculating the inequalities. Or, step 5 is to obtain the weight value by minimizing the total violation amount, in case there is no weight value in step 4. Results: The typical 4 process capability indices, namely, $C_p$, $C_{pk}$, $C_{pm}$, $C_{pmk}$ are utilized for the proposed procedure. Conclusion: The proposed procedure can provide a weight value in WMSE based on the objective quality performance criteria, not on the decision maker's subjective judgments or experiences.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.sup1
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• pp.46-51
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• 2008

Gastrointestinal stromal tumors (GIST) are the most common mesenchymal neoplasm of the gastrointestinal tract, and can be distinguished from the smooth muscle or neural tumors in approximately 95% of patients by expression of the KIT receptor tyrosine kinase (CD117). GISTs are known to have high malignant potential and none can be labeled definitely as benign. However, GISTs are unresponsive to standard sarcoma chemotherapy, and only complete surgical resection provides chance for cure. Although the imaging modality of choice is enhanced CT scan in patients with GIST, FDG PET can reflect the malignant potential of GIST. Clinical management of patients with GISTs has dramatically changed with the introduction of novel therapeutics, such as imatinib mesylate (Glivec). This has created a need to re-evaluate the existing criteria used to assess treatment response. FDG PET as functional imaging modality proved to be significantly more accurate than CT alone when assessing GIST response to imatinib. And, FDG PET and PET ICT have been found to be highly sensitive in detecting early response, and to be useful in predicting long-term response to imatinib in patients with recurrent or metastatic GISTs.

• New & Renewable Energy
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• v.3 no.2 s.10
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• pp.24-30
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• 2007

The transient response of PEMFC (proton exchange membrane fuel cell) is important criteria in the application of PEM fuel cell to real automotive system. In this work, using a transparent unit PEM fuel cell, the transient response and cathode flooding during load change are investigated. The cell voltage is acquired according to the current density change($0.3Acm^2$ to $0.6A/cm^2$) under various stoichiometry conditions and different flooding intensities, Also the cathode gas channel images are obtained by CCD imaging system simultaneously. The different level of undershoots appeared at the moment of load changes under different cathode stoichiometries and flooding intensities. It takes about 1s that the product water comes up onto the flow channel so that oxygen supply is temporarily blocked which causes voltage loss in that "undershoot". The correlation of the dynamic behavior with stoichiometry and cathode flooding is induced from the results of these experiments.

• Journal of Radiation Protection and Research
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• v.34 no.3
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• pp.151-154
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• 2009

The Radiation Emergency Plan (REP) can be divided into a technical and an administrative responses. The domestic NPP's REPs are reviewed from the viewpoint of the administrative response and improvement methods are also suggested in this treatise. The fields of the reviews are the composition of the emergency response organizations, the activation criteria of the organizations, the selection of the staffings and the reasonableness of the REP's volume. In addition, the limitations of the current radiation exercises are reviewed and the improvement method of the exercise is presented. It is expected that the suggested recommendations will be helpful in establishing useful REPs and making practical radiation exercises in Korea.

• Wind and Structures
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• v.13 no.6
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• pp.499-517
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• 2010

Advances in structural materials and construction methods have resulted in flexible and light tall buildings, making an assessment of structural safety during strong wind and serviceability/habitability during comparable medium/weak wind important design criteria. So far, lots of studies on suppressing the wind-induced responses have been carried out for tall buildings with aerodynamic modification. Most of the studies on aerodynamic modification have forced on the corner modification, while the studies on taper and set-back are limited. Changes of sectional shape through taper and set-back can modify the flow pattern around the models, encouraging more 3-dimensionalities, which results in reducing the wind-induced excitations. This paper discusses the characteristics of overturning moments and wind-induced responses of the tall buildings with height variations. The reduction of mean along-wind and fluctuating across-wind overturning moments are apparent in the suburban area than in urban area. A series of the response analyses, the rms displacement responses of the tall buildings with height variations are reduced greatly, while the rms acceleration responses are not necessarily reduced, showing dependences on wind direction.