• Molecules and Cells
• /
• 제23권2호
• /
• pp.132-137
• /
• 2007

With the advance of stem cell transplantation research, in vivo cell tracking techniques have become increasingly important in recent years. Magnetic resonance imaging (MRI) may provide a unique tool for non-invasive tracking of transplanted cells. Since the initial findings on the stem cell migration by MRI several years ago, there have been numerous studies using various animal models, notably in heart or brain disease models. In order to develop more reliable and clinically applicable methodologies, multiple aspects should be taken into consideration. In this review, we will summarize the current status and future perspectives of in vivo cell tracking technologies using MRI. In particular, use of different MR contrast agents and their detection methods using MRI will be described in much detail. In addition, various cell labeling methods to increase the sensitivity of signals will be extensively discussed. We will also review several key experiments, in which MRI techniques were utilized to detect the presence and/or migration of transplanted stem cells in various animal models. Finally, we will discuss the current problems and future directions of cell tracking methods using MRI.

• 한국산업융합학회 논문집
• /
• 제24권4_2호
• /
• pp.481-490
• /
• 2021

In the ultrasonic welding machine, when the load fluctuates, the L and C of the piezo element in the oscillation part change. As a result, the resonant frequency is changed, so it is necessary to match the operating frequency of the ultrasonic welding machine to the new resonant frequency. That is, in order to maximize the output of the oscillation unit of the ultrasonic welding machine, it is inevitable to follow the resonance frequency. Accordingly, many methods for following the resonant frequency are being actively studied. In addition, in order to check the effect of external inductance on the operation of the ultrasonic welding machine, The equivalent circuit of the piezo element was analyzed by including the external inductance for resonance in the equivalent circuit of the piezo element, and the method of selecting an appropriate inductance was described. In this paper, we propose a new system that allows the switching frequency of the inverter to tracking the resonance frequency even if the resonance frequency is changed due to the load of the ultrasonic welding machine.

• Journal of electromagnetic engineering and science
• /
• 제11권4호
• /
• pp.298-303
• /
• 2011

A capsular endoscope (CE) for inspection of the large intestine requires a motor for backward navigation against the autonomous travel in the intestine. This study proposes an HF power system for generating a magnetic field and for delivering wireless power to the internal or implanted medical devices. The magnetic field is generated by a wound coil (L) around a wooden frame, and the current is driven to the coil through a resonating capacitor (C). The characteristics of the resonance frequency shifting of the L-C series circuit are analyzed. A stable magnetic field intensity in the field coil is maintained by a specially designed frequency tracking system that automatically follows the L-C resonance frequency. Testing confirmed that the oscillation system tracks well the parameter changes of the electric components caused by the operating conditions or environmental variations.

• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 1995년도 추계학술대회 논문집
• /
• pp.442-445
• /
• 1995

This paper presents the position tracking control of a laser scanning mirror system in which piezoelectic actuator is incorporated. Using the shear mode of the piezoelectric actuator,angular oscillation of a laser scanning mirror is derived. Torsion bar is rhen designed and attached to the piezoelctric actuator in order to magnify the amplitude generated by the actuator. Finite element modeling and analysis are essntial for designing the piezoelectic actuator. The torsional resonance mode of the piezoelectric actuator is found from the model analysis of the actuator and the mechanical shear is matched with the driving frequency. Transfer function between the electrical excitation and the mechanical shear deformation at resonance frequency is found form the response of the actuator calculated by the finite element analysis and the governing equation of the system is derived from d'Alembert's principle. Tracking control performance for desired trajectory which is, in fact, sinusoidal curve is presented in order to demonstrate the validity of the proposed system.

• 한국소음진동공학회:학술대회논문집
• /
• 한국소음진동공학회 2003년도 추계학술대회논문집
• /
• pp.214-219
• /
• 2003

Recently, the optical disk drive that is thin in thickness has been demanded by the popularization of notebook PC. The device that controls the thickness of a drive is the height of optical pickup. Therefore, researches about this are going on and an asymmetric actuator is the good choice fur this target. However, the actuator of this design has troubles that a subsidiary resonance is likely to be actuated by discord between the center of force and the mass of renter. In this paper, relation between the tracking coil and the subsidiary resonance is analyzed and dynamic characteristics of an actuator are improved by using experiments design and response surface method.

• 한국소음진동공학회:학술대회논문집
• /
• 한국소음진동공학회 2000년도 춘계학술대회논문집
• /
• pp.1596-1600
• /
• 2000

We propose a novel adaptive feed forward controller (AFC) design method for rejecting the effect of micro actuator resonance in the design of dual-stage actuator servo systems for disk drives. Microactuator's resonance is one of important issues in dual-stage actuator servo, which varies up to ${\pm}10%$ per product and even during operation. We derive an adaptive algorithm for the proposed AFC design, which turns out to be identical to the delayed-x LMS algorithm which is a special form of the filtered-x LMS algorithm. In the algorithm, coefficients of the AFC are adapted by the residuals of constrained structure defined in such a way that the coefficients become time invariant. Contrary to the conventional AFC, it considers the phase delay of closed-loop transfer function at resonance frequency for system stability. We also apply an adaptive algorithm with frequency tracking capability. The frequency tracking algorithm is induced by the orthogonality of AFC coefficients. Computer simulations are carried out to demonstrate effect of the proposed AFCs.

• 대한자기공명의과학회:학술대회논문집
• /
• 대한자기공명의과학회.한국자기공명학회 2005년도 공동학술대회
• /
• pp.84-84
• /
• 2005

• International Journal of Korean Welding Society
• /
• 제1권1호
• /
• pp.31-38
• /
• 2001

For the horizontal fillet welding with one plate in a vertical position, there will be a higher tendency of weld metal falling down rather than for the butt-welding in flat position. Such phenomenon could bring about the overlap or deflection of weld pool, and consequently induce the poor mechanical strength of weldments. Therefore, a precise position control of welding torch in conjunction with the weld qualify plays an important role in welding robot applications. In the present study, an experimental method was proposed for deriving a mathematical model between the leg length and the welding conditions. Finally, an algorithm was proposed for weld seam tracking and improvement of the weld quality. The reliability of the proposed algorithm was evaluated through various experiments, which showed that the proposed algorithm can be very effective for tracking the weld line and simultaneously achieving the sound weld bead.

• 대한기계학회:학술대회논문집
• /
• 대한기계학회 2001년도 추계학술대회논문집A
• /
• pp.609-615
• /
• 2001

A turbo-fan is easily exposed to noise and vibration as against other industrial machines and the majority of them is subject to be damaged by vibration. The most usual problem of vibration in a turbo-fan is resonance so the case of being composed of iron sheet structure with low strength like a turbo-fan should be taken seriously. In this paper, FFT(Fast Fourier Transform) and Order tracking method were used to analyze factors of vibration in a turbo-fan and hereby with proper selection of vibration isolator, we wanted to reduce vibration of base. After Order tracking, we knew resonance occurred in rotational frequency 23 Hz(1400 rpm) at the casing and the bearing. After the test of base vibration using vibration isolators, the spring isolator was more effective than the robber isolator in the base vibration and the vibration isolating is more effective in the case that the isolating pad is adhered to the bottom of the isolating spring.

• 대한치매학회지
• /
• 제16권2호
• /
• pp.48-53
• /
• 2017

Background and Purpose Torrance Tests of Creative Thinking (TTCT) is a well-known and commonly used measure of creativity. However, the TTCT-induced creative hemodynamic brain activity is rarely revealed. The purpose of this study is to elucidate the neural correlates of creative thinking in the setting of a modified version of the figural TTCT adapted for an functional magnetic resonance imaging (fMRI) experiment. Methods We designed a blocked fMRI experiment. Twenty-five participants (11 males, 14 females, mean age $19.9{\pm}1.8$) were asked to complete the partially presented line drawing of the figural TTCT (creative drawing imagery; creative). As a control condition, subjects were asked to keep tracking the line on the screen (line tracking; control). Results Compared to the control condition, creative condition revealed greater activation in the distributed and bilateral brain regions including the left anterior cingulate, bilateral frontal, parietal, temporal and occipital regions as shown in the previous creativity studies. Conclusions The present revealed the neural basis underlying the figural TTCT using fMRI, providing an evidence of brain areas encompassing the figural TTCT. Considering the significance of a creativity test for dementia patients, the neural correlates of TTCT elucidated by this study may be valuable to evaluate the brain function of patients in the clinical field.