• Natural Product Sciences
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• v.27 no.2
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• pp.128-133
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• 2021

The Coumarin (1,2-benzopyrone) is the main secondary metabolite of Mikania laevigata Sch. Beep ex Baker and Mikania glomerata Spreng., which are popularly known as guaco. These plants have been used mainly in traditional medicine in the treatment of respiratory diseases because their bronchodilator effect. However, there are around 200 species of Mikania, which are quite similar in appearance. From these, only M. leavigata and M. glomerata have high concentrations of coumarins. In this line, the falsification of products Mikania based has been frequent. In this sense, this work demonstrated the application of the easy, fast, e not destructive method based in Nuclear Magnetic Resonance in quantitative mode (qNMR) for the determination of coumarin in both commercial and homemade guaco products. Thus, in the first step the compounds were extract from guaco leaves and syrups using chloroform (CHCl₃), with or without ultrasound. About the method, was linear with a R² = 0.9947 for 1,2-benzopyrone, with detection and quantification limits with were 0.11 and 0.36 mg mL^-1 respectively. In the same line, the method was safe with RSD <0.3% and with recovery ranging from 93-101%. To confirm the applicability of the method, in the last step was applied to 10 real samples (6 from leaves and 4 from syrups). The content of the coumarin in the leaf extract ranged from 0.62 to 1.30 mg mL^-1. For syrups I, II and IV, the content of coumarin was in accordance with the manufacturers. However, for de Syrup III, the concentration was 155% higher. In summary, the qNMR is a rapid method with minimal sample preparation that can be used to quantify coumarin in home-made plant extracts as well as in commercial samples as syrup for instance. This method is applicable for quality control of different plants-based products.

• Journal of Hydrogen and New Energy
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• v.34 no.2
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• pp.155-161
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• 2023

Recently, a study on alternative and renewable energy is being conducted due to energy depletion and environmental problems. In particular, a hydrogen has the advantage of converting and storing the remaining energy into water-electrolyzed hydrogen through renewable energy generation. In general, due to reasons such as insulation problems, a study on high-pressure hydrogen storage tanks and related parts has recently been conducted. However, in the case of liquid hydrogen, the volume can be reduced by about 800 times or more compared to high-pressure hydrogen gas, so the study on this is needed as a technology that can increase energy density. In this study, the evaporation characteristics were analyzed under fixed heat flux conditions for liquid hydrogen storage tanks and the change in thermal stratification according to sloshing was analyzed. The heat flux condition was fixed at 250 W/m² and the horizontal resonance frequency of the primary mode was applied to the storage tank. As a result, it was confirmed that the thermal stratification phenomenon decreased compared to the case where the slashing was not present due to forced convection when the slashing was present.

• Proceedings of the International Microelectronics And Packaging Society Conference
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• 2005.09a
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• pp.201-212
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• 2005

[ $Epoxy/BaTiO_3$ ] composite embedded capacitor films (ECFs) were newly designed fur high dielectric constant and low tolerance (less than ${\pm}15\%$) embedded capacitor fabrication for organic substrates. In terms of material formulation, ECFs are composed of specially formulated epoxy resin and latent curing agent, and in terms of coating process, a comma roll coating method is used for uniform film thickness in large area. Dielectric constant of $BaTiO_3\;&\;SrTiO_3$ composite ECF is measured with MIM capacitor at 100 kHz using LCR meter. Dielectric constant of $BaTiO_3$ ECF is bigger than that of $SrTiO_3$ ECF, and it is due to difference of permittivity of $BaTiO_3\;and\;SrTiO_3$ particles. Dielectric constant of $BaTiO_3\;&\;SrTiO_3$ ECF in high frequency range $(0.5\~10GHz)$ is measured using cavity resonance method. In order to estimate dielectric constant, the reflection coefficient is measured with a network analyzer. Dielectric constant is calculated by observing the frequencies of the resonant cavity modes. About both powders, calculated dielectric constants in this frequency range are about 3/4 of the dielectric constants at 1 MHz. This difference is due to the decrease of the dielectric constant of epoxy matrix. For $BaTiO_3$ ECF, there is the dielectric relaxation at $5\~9GHz$. It is due to changing of polarization mode of $BaTiO_3$ powder. In the case of $SrTiO_3$ ECF, there is no relaxation up to 10GHz. Alternative material for embedded capacitor fabrication is $epoxy/BaTiO_3$ composite embedded capacitor paste (ECP). It uses similar materials formulation like ECF and a screen printing method for film coating. The screen printing method has the advantage of forming capacitor partially in desired part. But the screen printing makes surface irregularity during mask peel-off, Surface flatness is significantly improved by adding some additives and by applying pressure during curing. As a result, dielectric layer with improved thickness uniformity is successfully demonstrated. Using $epoxy/BaTiO_3$ composite ECP, dielectric constant of 63 and specific capacitance of 5.1nF/cm2 were achieved.

• Journal of Biomedical Engineering Research
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• v.24 no.2
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• pp.121-126
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• 2003

The purpose of this work was to assess and quantify whether the beneficial effects in long-term gas exchange at exciting frequency were obtained at different frequencies as well and then to develop a vibrating intravascular lung assist device(VIVLAD), for Patients suffering from acute respiratory distress syndrome(ARDS) or chronic respiratory problems. We investigate the optimal condition of the frequency band excited with new vibrator at state of limit hemolysis when blood hemolysis came to through a membrane vibration action. The experimental design and procedures were given for a device used to assess the effectiveness of membrane vibrations. Quantitative experimental measurements were performed to evaluate the performance of the device . and to identify membrane vibration dependence on blood hemolysis. We developed an analytical solution for the hydrodynamics of flow through a bundle of sinusoidally vibrated hollow fibers that is used to provide some insight into how wall vibrations might enhance the performance of the VIVLAD. In the result, it was measured that the effect of various excited frequencies in gas transfer rate and hemolysis from the maximum gas transfer rate at no vibration when the maximum gas transfer rates showed at module type 6, module type 6 consisted of 675 hollow fiber membranes The maximum oxygen transfer rate was caused by the occurrence of maximum amplitude and transfer of vibration to hollow fiber membranes when it was excited by the frequency band of 7Hz at each blood flow rate. because this frequency became the End mode resonance frequency of the flexible in blood flow. Also, when module type 6 was excited at an excited frequency of 7Hz. blood hemolysis was low. Therefore, we decided that the limit of hemolysis frequency is 7Hz . because maximum amplitude occurred at this frequency.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.21 no.6
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• pp.651-659
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• 2010

In this paper, a new six-port direct conversion receiver for high-speed multi-band multi-mode wireless communication system such as software defined radio(SDR) is proposed. The designed receiver is composed of two CMOS four-port BPSK receivers and a dual-band one-stage polyphase filter for quadrature LO signal generation. The four-port BPSK receiver, implemented in 0.18 ${\mu}m$ CMOS technology for the first time in microwave-band, is composed of two active combiners, an active balun, two power detector, and an analog decoder. The proposed polyphase filter adopt type-I architecture, one-stage for reduction of the local oscillator power loss, and LC resonance structure instead of using capacitor for dual-band operation. In order to extent the operation RF bandwidth of the proposed six-port receiver, we include I/Q phase and amplitude calibration scheme in the six-port junction and the power detector. The calibration range of the phase and amplitude mismatch in the proposed calibration scheme is 8 degree and 14 dB, respectively. The validity of the designed six-port receiver is successfully demonstrated by modulating M-QAM, and M-PSK signal with 40 Msps in the two-band of 900 MHz and 2.4 GHz.

• Journal of Animal Environmental Science
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• v.14 no.1
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• pp.53-60
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• 2008

This study was carried out to measure and analyze the vibration levels and modes produced by a hopper type feeder used at laying hen farms, to prevent the vibration resonance and to reduce the vibration of the hopper type feeder (6-tier). The most vibration in a layer house were produced by hopper type feeder as shown the previous study. According to the measurement results, the ratio of transmissibility was as high as 100-638% for natural frequency of 170 Hz or less. And vibration simulations were taken by the results of vibration mode analysis and the weakest points to vibrations were determined accordingly. Then measurement and analysis were taken for those points. The quantities of vibration were 4.6354-4.9118 g($g=9.81^m/s^2$) by axis. In this study, it was found that hopper type feeder generated vibration as much as to influence the ratio of laying eggs of layer. And by the analysis of vibration on the weakest points, design methods and equipment were suggested for isolating/reducing of vibration by each axis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.10
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• pp.6977-6984
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• 2015

It is faced with the necessity of multi roll forming process of the ball slide rail which is made by adding the separate manufacturing processes, piercing, bending, trimming, to the roll forming process of a continuous plastic deformation, to improve the quality. However, the vibration and noise of the press machine in this process leads to the quality degradation of slide rail manufactured in this process. In this study, the roll was designed considering the optimal strain rates by the roll forming program with finite element method. And to estimate the static stability of the multi process the Von-Mises stress and deformation on the press was calculated with a structural analysis program. Also, to avoid driving systems in the resonance region their natural frequencies in the 1st and 2nd mode were calculated through the modal analysis. To verify its dynamic stability improvement the magnitudes of noise and vibration in the existing and studied system were compared using a microphone and accelerometers. And the widths and surface roughnesses of the rails which had been produced in the existing and studied process were measured. Therefore, it is known that multi roll forming process is stable in the analytical and experimental study.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2013.04a
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• pp.835-841
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• 2013

Modern solid-state gyroscopes (HRG) with hemispherical resonators from high-purity quartz glass and special surface superfinishing and ultrathin gold coating become the best instruments for precise-grade inertial reference units (IRU) targeting long-term space missions. Designing of these sensors could be a notable contribution into development of Korea as a space nation. In participial, 40mm diameter thin-shell resonator from high-purity fused quartz, fabricated as a single-piece with its supporting stem has been designed, machined, etched, tuned, tested, and delivered by STM Co. (ATS of Ukraine) several years ago; an extremely-high Q-factor (upto 10~20 millions) has been shown. Understanding of the best way how to match such a unique sensor with inner glass assembly of the gyro means how to use the high potential in a maximal extent; and this has become the urgent task. Inner quartz glass assembly has a very thin indium (In) layer soldered the resonator and its silica base (case), but effects of internal resonances between operational modal pair of the shell-cup and its side (parasitic) modes can notable degrade the potential of the sensor as a whole, instead of so low level of resonator's intrinsic losses. Unfortunately, there are special combinations of dimensions of the parts (so-called, "resonant sizes"), when intensive losses of energy occurs. The authors proposed to use the length of stem's fixture as an additional design parameter to avoid such cases. So-called, a cyclic scheme of finite element method (FEM) and ANSYS software were employed to estimate different combinations of gyro assembly parameters. This variant has no mismatches of numerical origin due to FEM's discrete mesh. The optimum length and dangerous "resonant lengths" have been found. The special attention has been paid to analyses of 3D effects in a cup-stem transient zone, including determination of a difference between the positions of geometrical Pole of the resonant hemisphere and of its "dynamical Pole", i.e., its real zone of oscillation node. Boundary effects between the shell (cup) and 3D short "beams" (inner and outer stems) have been ranged. The results of the numerical experiments have been compared with the classic model of a quasi-hemispherical shell band with inextensional midsurface, and the solution using Rayleigh's functions of the $1^{st}$ and $2^{nd}$ kinds. To guarantee the truth of the recommended sizes to a designer of the real device, the analytical and FEM results have been compared with experimental data for a party of real resonators. The consistency of the results obtained by different means has been shown with errors less than 5%. The results notably differ from the data published earlier by different researchers.

• The Korean Journal of Food And Nutrition
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• v.27 no.3
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• pp.532-537
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• 2014

Cortex Phellodendri (CP) is derived from the dried bark of Phellodendron amurense. It has been widely used as a drug in traditional Korea medicine for treating diarrhea, jaundice, swelling pains in the knees and feet, urinary tract infections, and infections of the body surface. Many analytical methods have been used to study oriental herbal medicines, such as thin-layer chromatography, column liquid chromatography, and high performance liquid chromatography (HPLC). In this study, preparative centrifugal partition chromatography (CPC) was successfully carried out in order to separate pure compounds from a CP methanol extract. The optimum two-phase CPC solvent system was composed of n-butanol: acetic acid: water (4:1:5 v/v/v). The flow rate of the mobile phase was 3 mL/min in ascending mode with rotation at 1,000 rpm. The CPC-separated fraction and purification procedures were carried out by preparatory HPLC. The $^1H$ NMR spectrum revealed that the resonances at ${\delta}$ 4.10 and 4.20 ppm corresponded to three protons ($-OCH_3$), whereas those at ${\delta}$ 6.10 ppm corresponded to two protons ($-OCH_2O-$). Further, two aromatic protons (H-11 and H-12) conveys a doublet-doublet pattern. The H-11 doublet and H-12 doublet appear at ${\delta}$ 7.98 and 8.11, respectively. The $^{13}C$ NMR. spectrum showed a tetrasubstituted with a methylenedioxy group at C2 and C3, and two methoxy groups at C9 and C10. The chemical structure of the berberine was identified by $^1H$, $^{13}C$-nuclear magnetic resonance and electrospray ionization-mass spectroscopy spectral data analysis.

• Journal of the Korean Society of Marine Environment & Safety
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• v.22 no.7
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• pp.900-905
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• 2016

The field of power system harmonics has been receiving a great deal of attention recently. This is primarily due to the fact that non-linear (or harmonic-producing) loads comprise an ever-increasing portion of what is handled at a typical industrial plant. The incidence rate of harmonic-related problems is low, but awareness of harmonic issues can still help increase offshore power plant system reliability. On the rare occasion that harmonics become a problem, this is either due to the magnitude of harmonics produced or power system resonance. This harmonic study used an electrical configuration for the offloading scenario of a Floating LNG (FLNG) unit, considering power load. This electrical network configuration is visible in the electrical network load flow study part of the project. This study has been carried out to evaluate the performance of an electric power system, focusing on the harmonic efficiency of an electrically driven motor system to ensure offshore plant safety. In addition, the design part of this study analyzed the electric power system of an FLNG unit to improve the safety of operation and maintenance.