• 비파괴검사학회지
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• 제31권5호
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• pp.479-486
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• 2011

의료영상을 기반으로 한 경동맥 분기부 혈류유동장 전산유체역학 해석의 수행에 있어 입구부 경계 조건 도출을 위한 환자 특정 시간 변동 상세 유속 분포를 얻는 것은 일반적으로 쉽지 않다. 그러므로 대부분의 경우 계측된 혈류량을 바탕으로 이상적인 축대칭 완전발달 유속 분포를 적용하게 된다. 그러나 MRI로 직접 계측한 총경동맥 혈류 유속분포를 적용한 기존의 연구에서 입구부 유속분포 경계 조건이 경동맥 분기부 혈류 유동장 해석 결과에 중요한 영향을 미친다는 것을 보였으며, 특히 계측된 혈류 유속분포가 전형적인 Dean type 유동과 다른 독특한 형태를 가진다는 것을 보고하였다. 본 연구에서는 이러한 독특한 형태의 유속 분포가 경동맥 입구부 형상의 이차곡률에 의해 생성됨을 보이고, 직접 경동맥 분기부 유동장 CFD 해석의 경계 조건으로 적용하여 이의 영향을 조사하였다. 이를 통하여 충분한 길이의 실제 경동맥 입구부 형상을 적용 할 경우, 입구부 경계 조건의 영향이 의료영상으로 부터 혈관 형상을 도출하는 과정에서 불가피하게 유기되는 영상 처리 오차에 의한 영향에 비해 상대적으로 크지 않음을 알 수 있었다.

• 한국전자파학회논문지
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• 제19권12호
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• pp.1367-1374
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• 2008

음의 유전율 및 투자율을 갖도록 고안된 메타 물질을 안테나 상부 덮개(superstrate)로 사용한 와이브로(Wibro: wireless broadband internet) 기지국용 고 이득 Fabry-$P{\acute{e}}rot$ 공진기 안테나를 제안한다. 안테나의 상부 덮개로 사용된 새로운 메타 물질은 기존의 PCB 기술로 쉽게 제작 가능하도록 평판형으로 설계되었으며, 와이브로 서비스 주파수 대역 근방에서 음의 굴절률 및 '1'보다 작은 저 굴절률 값을 갖는다. 안테나의 이득 증대 효과를 유효매질 관점에서 추출된 메타 물질의 저 굴절률 특성과 Fabry-$P{\acute{e}}rot$ 공진기의 공진 조건이라는 두 가지 측면에서 분석하였다. 단일 정사각형 패치 안테나가 공진기 내부의 신호 피더로 사용되었으며, Fabry-$P{\acute{e}}rot$ 공진 조건을 충족시키기 위해 피더와 메타 물질 상부 덮개 사이의 이격 거리는 유전체 층을 포함한 접지면의 반사 위상과 메타 물질 상부 덮개의 반사 위상을 함께 고려하여 설정하였다. 시뮬레이션을 통한 예측 특성과 실험 결과가 잘 일치하였으며, 이를 통하여 본 논문에서 제시한 설계 방법이 타당함을 입증할 수 있었다.

• 한국소음진동공학회논문집
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• 제15권9호
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• pp.1100-1107
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• 2005

The failure of blades frequently happened in the 300 MW LP(low pressure) turbine until now and they are maintaining the blades periodically during outage. So the blade-disk system is analysed by FEM in order to identify the main cause of failure of blade row. It is found that the stress of root's hole is highest in comparison with other parts from the result of the steady stress analysis. Also, the two dangerous frequencies which is related to the resonance condition are found in the interference diagram. One is 1,316 Hz. The other is 2,981 Hz which is related to the 1 nozzle passing frequency. The dynamic stress analysis is performed to identify more accurate root cause for failure of blade row It is confirmed that the dynamic stress of the former is higher than one of the latter From these results, it is concluded that the former has deeply something to do with the failure of blades more than the tatter. Based on versatile investigation and deliberation, the change of blade's grouping is determined to avoid the resonance condition with the operating speed. After the blade grouping is changed, the former frequency vanish completely but the latter is still in existence in the interference diagram. Fortunately, It is confirmed that the dynamic stress of the new blade grouping is lower than one of the old blade grouping. 2 years has passed since modification and the LP turbine is operated well without failure so far.

• 말소리와 음성과학
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• 제4권3호
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• pp.179-186
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• 2012

The aims of this study are to consider auditory physiological characteristics and to confirm audiological evaluation and interpretation in regards to cases of sensorineural hearing loss that observe an abnormal AB gap. Vestibulosaccular hearing occurs when there is an abnormally large air-bone gap (AB gap) in sensorineural hearing loss, also known as pure cochlear conductive hearing loss. Generally, an AB gap is caused by damage to the external and/or middle ear. In conductive hearing loss, loss of air condition hearing occurs due to a loss of resonance in the outer ear and/or impedance mismatching in the middle ear. Most of these types of hearing loss can be treated medically and surgically. However, there is no medical treatment for an AB gap in sensorineural hearing loss and hearing loss can worsen gradually or suddenly. In addition, many studies have reported that head trauma makes hearing loss even more serious. Therefore, in order to differentiate between conductive hearing losses, it is important to check whether or not there is an enlarged vestibular aqueduct by means of temporal bone computerized tomography and/or magnetic resonance imaging.

• Bulletin of the Korean Chemical Society
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• 제27권10호
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• pp.1655-1658
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• 2006

The solution of $[Ru(phen)_2(dppz)]^{2+}$ and SDS has high Resonance Light Scattering (RLS) signals due to $[Ru(phen)_2(dppz)]^{2+}$ assemble on the surface of the SDS micelle. Because of the high affinity ($KB\geq10^6\;L\;mol^{-1}$) between $[Ru(phen)_2(dppz)]^{2+}$ and DNA, the adding of DNA in the solution of $[Ru(phen)_2(dppz)]^{2+}$-SDS makes the dissociation of $[Ru(phen)_2(dppz)]^{2+}$-SDS, and results in decreasing of the RLS signals and increasing of the absorbance. Based on this, a novel method is proposed for DNA assay. Under optimum condition, good linear relationship was obtained within the concentration range of 0.018-1.26 $\mu g\;mL^{-1}$, the linear equation is $I_{RLS}$ = 504.8-348.8 c (c: $\mu g\;mL^{-1}$) and the correlation coefficient (r) is 0.9992. The detect limit for calf thymus DNA is 8.6 ng $mL^{-1}$. The proposed method was successful applied to determine the extracted colibacillus plasmid DNA.

• 수산해양기술연구
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• 제35권3호
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• pp.312-322
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• 1999

A ultrasonic transduce with a single acoustic matching layer has been designed as an attempt to increase the bandwidth of underwater transducer. The wideband resonance condition was accomplished by attaching a single matching layer on the front face of a ceramic resonator composed of a piezoelectric bar, a taper part and a head part. A modified Mason's model was used for the performance analysis and the design of transducers, and the constructed transducers were tested experimentally and numerically by changing the impedance and thickness of the matching layer in the water tank.The obtained results are summarized as follows:1. Measured resonant and antiresonant frequencies of the piezoelectric transducer with no matching layer in air were 24.7 kHz and 25.6 kHz, respectively. 2. Two resonant frequencies of the piezoelectric transducer with a single matching layer were 21.7 kHx and 26.9 kHz, respectively, in air and 21.4 kHz and 22.7 kHz, respectively, with a water load.3. Two distinct resonance peaks in the transmitting voltage response(TVR) of the developed transducer were observed at 22.0 kHz and 25.8 kHz, respectively, with center frequency of 24.0 kHz. The values of TVR at these frequencies were 130.1 dB re $1 \muPa$/V at 22.0 kHz and 128.5 dB re $1 \muPa$/V at 25.8 kHz, respectively.Reasonable agreement between the experimental results and the numerical values was achieved.

• 한국자기공명학회논문지
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• 제19권2호
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• pp.54-60
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• 2015

Papiliocin, from the swallowtail butterfly, Papilio xuthus, shows high bacterial cell selectivity against Gram-negative bacteria. Recently, we designed a 22mer analog with N-terminal helix from $Lys^3$ to $Ala^{22}$, PapN. It shows outstanding antimicrobial activity against Gram-negative bacteria with low toxicity against mammalian cells. In this study, we determined the 3-D structure of PapN in 300 mM DPC micelle using NMR spectroscopy and investigated the interactions between PapN and DPC micelles. The results showed that PapN has an amphipathic ${\alpha}$-helical structure from $Lys^3$ to $Lys^{21}$. STD-NMR and DOSY experiment showed that this helix is important in binding to the bacterial cell membrane. Furthermore, we tested antibacterial activities of PapN in the presence of salt for therapeutic application. PapN was calcium- and magnesium-resistant in a physiological condition, especially against Gram-negative bacteria, implying that it can be a potent candidate as peptide antibiotics.

• 한국자기공명학회논문지
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• 제15권1호
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• pp.25-39
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• 2011

Syndecan-4 is a transmembrane heparan sulfate proteoglycan, which is a coreceptor with integrins in cell adhesion. To get better understand the mechanism and function of Syndecan-4, it is critical to elucidate the three-dimensional structure of a single transmembrane spanning region of them. Unfortunately, it is hard to prepare the peptide because syndecan-4 is membrane-bound protein that transverse the lipid bilayer of the cell membrane. Generally, the preparation of transmembrane peptide sample is seriously difficult and time-consuming. In fact, high yield production of transmembrane peptides has been limited by experimental adversities of insufficient yields and low solubility of peptide. Here, we demonstrate experimental processes and results to optimize expression, purification, and NMR measurement condition of Syndecan-4 transmembrane peptide.

• 수산해양기술연구
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• 제32권4호
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• pp.421-431
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• 1996

From comparing the impact dynamic absorber with the impact damper in the auxiliary vibration system with the conventional dynamic absorber, the following conclusions are obtained as follows ; 1. Recognizing that the amplitude restraining effect of the impact dynamic absorber become resonable in a comparison of conventional one development of an improved dynamic absorber may be probable. 2. With increasing the frequency ratio, the 1st resonance peak is higher but the 2nd one gets lower. In addition, the frequency ratio is peak located at the same resonance. 3. The optimum impact clearance is smaller and the vibration constraining effect becomes better with and increase in the mass of impact ball. And it is recognizable that the optimum tuning frequency ratio and impact clearance in an accordance with the mass ratio are varied. 4. The optimum tuning condition becomes gradually lower than the case of r=1 and maximum amplitude becomes lower with an increment in the mass ratio. However, the impulse clearance is larger and the working range of restraining vibration amplitude become smaller with a decrement in the mass of impact ball.

• 한국해양환경ㆍ에너지학회지
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• 제18권4호
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• pp.282-290
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• 2015

부이의 수직운동으로부터 파랑에너지를 추출하는 파력발전기의 추출효율을 극대화하기 위하여 Sheng et al.(2015)이 제안한 래칭 제어기법을 적용하였다. 래칭 제어기법은 부이를 구속하는 래칭 시간을 조절하여 추출효율을 높이는 위상제어 방법이다. 래칭 제어기법을 규칙파중 수직운동하는 부이에 적용한 결과, 공진조건을 만족하지 않았음에도 불구하고 부이의 운동속도와 추출파워는 크게 증가하였다. 부이의 수직운동으로부터 파랑에너지를 흡수하는 파력발전기에 이러한 래칭 제어기법을 도입하면 추출파워의 증가와 더불어 부이의 흘수와 PTO감쇠력을 줄일 수 있어 제작비용을 크게 낮출 수 있다.