• Title/Summary/Keyword: Resistance value

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Evaluation of Reverse Hybridization Assay for Detecting Fluoroquinolone and Kanamycin Resistance in Multidrug-Resistance Mycobacterium tuberculosis Clinical Isolates (다제내성결핵 균주에서 Reverse Hybridization Assay를 이용한 Fluoroquinolone, Kanamycin 신속 내성 검사의 유용성)

  • Park, Chin-Su;Sung, Nack-Moon;Hwang, Soo-Hee;Jeon, Jae-Hyun;Won, Young-Sub;Min, Jin-Hong;Kim, Cheon-Tae;Kang, Hyung-Seok
    • Tuberculosis and Respiratory Diseases
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    • v.72 no.1
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    • pp.44-49
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    • 2012
  • Background: Multidrug-resistant tuberculosis (MDR-TB) is an increasing public health problem and poses a serious threat to global TB control. Fluoroquinolone (FQ) and aminoglycoside (AG) are essential anti-TB drugs for MDR-TB treatment. REBA MTB-FQ$^{(R)}$ and REBA MTB-KM$^{(R)}$ (M&D, Wonju, Korea) were evaluated for rapid detection of FQ and kanamycin (KM) resistance in MDR-TB clinical isolates. Methods: M. tuberculosis (n=67) were isolated and cultured from the sputum samples of MDR-TB patients for extracting DNA of the bacilli. Mutations in genes, gyrA and rrs, that have been known to be associated with resistance to FQ and KM were analyzed using both REBA MTB-FQ$^{(R)}$ and REBA MTB-KM$^{(R)}$, respectively. The isolates were also utilized for a conventional phenotypic drug susceptibility test (DST) as the gold standard of FQ and KM resistance. The molecular and phenotypic DST results were compared. Results: Sensitivity and specificity of REBA MTB-FQ$^{(R)}$ were 77 and 100%, respectively. Positive predictive value and negative predictive value of the assay were 100 and 95%, respectively, for FQ resistance. Sensitivity, specificity, positive predictive value and negative predictive value of REBA MTB-KM$^{(R)}$ for detecting KM resistance were 66%, 94%, 70%, and 95%, respectively. Conclusion: REBA MTB-FQ$^{(R)}$ and REBA MTB-KM$^{(R)}$ evaluated in this study showed excellent specificities as 100 and 94%, respectively. However, sensitivities of the assays were low. It is essential to increase sensitivity of the rapid drug resistance assays for appropriate MDR-TB treatment, suggesting further investigation to detect new or other mutation sites of the associated genes in M. tuberculosis is required.

An international Comparison Measurement of Silicon Wafer Sheet Resistance using the Four-point Probe Method

  • Kang, Jeon-Hong;Ying, Gao;Cheng, Yuh-Chuan;Kim, Chang-Soo;Lee, Sang-Hwa;Yu, Kwang-Min
    • Journal of Electrical Engineering and Technology
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    • v.10 no.1
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    • pp.325-330
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    • 2015
  • With approval from the Asia Pacific Metrology Program Working Group on Materials Metrology (APMP WGMM), an international comparison for sheet resistance standards for silicon wafers was firstly conducted among Korea Research Institute of Standards and Science (KRISS) in Korea, CMS/ITRI in Taiwan, and NIM in China, which are national metrology institutes (NMIs), from August 2011 to January 2012. The sheet resistance values of the standards are $10{\Omega}$, $100{\Omega}$, and $1000{\Omega}$; the measurement was conducted in sequence at KRISS, CMS/ITRI, NIM, and KRISS again using the four-point probe method with single and dual configuration techniques. The reference value for the measurement results of the three NMIs was obtained through averaging the values of the three results for each sheet resistance range. The differences between the reference value and the measured values is within 0.22% for $10{\Omega}$, 0.17% for $100{\Omega}$, and 0.12% for $1000{\Omega}$. Therefore, the international consistency for conducting sheet resistance measurements is confirmed within 0.22% through the APMP WGMM approved comparison.

THE FRACTURE RESISTANCE OF CERAMOMETAL CROWN WITH VARIOUS COPING DESIGN (Coping design에 따른 도재전장관의 파절강도에 관한 연구)

  • Chung Wan-Mo;Dong Jin-Keun;Jin Tai-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.30 no.1
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    • pp.125-132
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    • 1992
  • The purpose of this study was to evaluate the effect of the metal coping design on the fracture resistance of ceramometal crown. The Ni-Cr alloy(Supranium, Krupp Co., German) and Vaccm-fired porcelain powder(Vita VMK 689, Vita Co., Germany) were used in this study. The measurement of fracture resisitance of ceramometal crown was done with Instron Universial Testing Machine(Instro Co., Model no.4201). The obained results were as fellows : 1. The fracture resistance measured at the buccal cusp tip was the highest value in the group that those position of ceramometal junction was 2mm superior to the lingual finshing margin(100.25Kg) and the fracture resistance revealed on order of the group that those position was 2mm buccal to the central groove(51.64Kg). 2. The fracture resistance measured at the central groove was higher value in the group that those position was 2mm lingual to the central groove than in the group that those position was 2mm lingual to the central groove than in the group that those position was 2mm superior to lingual finishing margin(132.48Kg). 3. In all cases, the fracture resistance at the central groove was higher than that at the buccal cusp tip.

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In-situ Measurement Technique for Thermal Performance of Building Wall Excluding Surface Heat Transfer Resistance (표면 열전달 저항이 배제된 건물 벽체 열성능 현장 측정 기법)

  • Kim, Seungchul;Kim, Sangbong;Nah, Hwanseon
    • KEPCO Journal on Electric Power and Energy
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    • v.6 no.2
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    • pp.151-155
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    • 2020
  • In this paper, a new experimental method to determine the thermal resistance of building wall was proposed by improving the heat flow method (HFM) based on the air-surface temperature ratio theory. This technique measures the thermal resistance of the wall excluding the inner and outer surface heat transfer resistance. Unlike conventional HFM, this value can be compared directly with the theoretical reference value. Its performance was verified using three mock-up structures with a theoretical thermal transmittance of 0.5, 3.3, and 0.18 W/㎡·K respectively. After measuring the variations in the temperature and heat transfer rate of the mock-ups for 383 hours, the thermal transmittances were determined to be 0.47, 3.10, and 0.18 W/㎡·K, which corresponded to errors of 5.2, 6.2 and 0.5%, respectively, compared to the theoretical values. It was concluded that this technique can directly compare the thermal resistance of the wall between the existent stage and initial stage after construction.

Multi-objective Fuzzy-optimization of Crowbar Resistances for the Low-Voltage Ride-through of Doubly Fed Induction Wind Turbine Generation Systems

  • Zhang, Wenjuan;Ma, Haomiao;Zhang, Junli;Chen, Lingling;Qu, Yang
    • Journal of Power Electronics
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    • v.15 no.4
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    • pp.1119-1130
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    • 2015
  • This study investigates the multi-objective fuzzy optimization of crowbar resistance for the doubly fed induction generator (DFIG) low-voltage ride-through (LVRT). By integrating the crowbar resistance of the crowbar circuit as a decision variable, a multi-objective model for crowbar resistance value optimization has been established to minimize rotor overcurrent and to simultaneously reduce the DFIG reactive power absorbed from the grid during the process of LVRT. A multi-objective genetic algorithm (MOGA) is applied to solve this optimization problem. In the proposed GA, the value of the crowbar resistance is represented by floating-point numbers in the GA population. The MOGA emphasizes the non-dominated solutions and simultaneously maintains diversity in the non-dominated solutions. A fuzzy-set-theory-based is employed to obtain the best solution. The proposed approach has been evaluated on a 3 MW DFIG LVRT. Simulation results show the effectiveness of the proposed approach for solving the crowbar resistance multi-objective optimization problem in the DFIG LVRT.

Damage Monitoring of CP-GFRP/GFRP Composites by Measuring Electrical Resistance

  • Shin, Soon-Gi;Kwon, Yong-Jung
    • Korean Journal of Materials Research
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    • v.20 no.3
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    • pp.148-154
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    • 2010
  • It is necessary to develop new methods to prevent catastrophic failure of structural material in order to avoid accidents and conserve natural and energy resources. Design of intelligent materials with a self-diagnosing function to prevent fatal fracture of structural materials was achieved by smart composites consisting of carbon fiber tows or carbon powders with a small value of ultimate elongation and glass fiber tows with a large value of ultimate elongation. The changes in electrical resistance of CF-GFRP/GFRP (carbon fiber and glass fiber-reinforced plastics/glass fiber-reinforced plastics) composites increased abruptly with increasing strain, and a tremendous change was seen at the transition point where carbon fiber tows were broken. Therefore, the composites were not to monitor damage from the early stage. On the other hand, the change in electrical resistance of CP-GFRP/GFRP (carbon powder dispersed in glass fiber-reinforced plastics/glass fiber-reinforced plastics) composites increased almost linearly in proportion to strain. CP-GFRP/GFRP composites are superior to CF-GFRP/GFRP composites in terms of their capability to monitor damage by measuring change in electrical resistance from the early stage of damage. However, the former was inferior to the latter as an application because of the difficulties of mass production and high cost. A method based on monitoring damage by measuring changes in the electrical resistance of structural materials is promising for improved reliability of the material.

Fault Detection and Isolation for the Inverter of BLDC Motor Drive using EKF (EKF를 이용한 BLDC 모터 구동기 인버터의 고장 검출 및 분리)

  • Kim, SunKi;Seong, SangMan;Kang, Kiho
    • Journal of Institute of Control, Robotics and Systems
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    • v.20 no.7
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    • pp.706-712
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    • 2014
  • The inverters used to drive Brushless DC motors (BLDC) include switching devices such as FETs and the faults in FETs cause severe performance degradation in systems where a BLDC acts as actuator. This paper presents a fault detection and isolation method for the FETs of an inverter for BLDC motor control systems, which is based on the EKF (Extended Kalman filter). Firstly, an equivalent circuit model for a BLDC motor plus its inverter system was derived. Secondly, a state-space equation was established, where the on-resistance of the FETs is expressed as a state variable and the EKF equation estimates the on-resistance. If the estimated resistance differs greatly from the known value, it can be asserted that there is a fault on that FET. Thirdly, the local convergence of the established EKF was proved. Finally, through the experiments, the performance of the proposed method was verified. The results show that the on-resistance is estimated close to the value specified in the FET data sheet in normal operation, whereas the estimated resistance is a much larger value than the normal one in case an FET fault occurs. Therefore, it is confirmed that the proposed fault detection and isolation method works appropriately in real systems.

The Resistance Characteristics and Reliability Evaluation of an Insulation Ring Type of Corrugated Stainless Steel Tubing(CSST) (절연링형 금속플렉시블호스(CSST)의 저항 특성 및 신뢰성 평가)

  • Lee, Jang-Woo;Kim, Jeom-Sik;Choi, Chung-Seog
    • Journal of the Korean Society of Safety
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    • v.31 no.6
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    • pp.25-31
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    • 2016
  • This paper has analyzed the structure, applicable regulations and the resistance characteristics of insulation ring type of CSST (Corrugated Stainless Steel Tubing for Gas). With the flammability test conducted in accordance with KS C IEC 60811-1-1, the evaluation of insulation resistance, temperature characteristics, and reliability has been conducted. An insulation ring type CSST consists of protective coating, tube, nut, insulation ring, packing, socket, and ball valve. Connecting an insulation ring type CSST to gas tubings for gas appliance is not permitted, moreover, the product shall be installed inside a sleeve pipe in case of buried installation such as the ceiling. Damages on protective coating and tube were detected when fire was applied to the test sample with a portable torch for 60 seconds. The insulation resistance of a normal product was $49.59M{\Omega}$, while that of the product completed the flammability test reduced to $9.21M{\Omega}$. The mean insulation resistance within the confidence Interval of 95% using the mini tap program 17 was $49.59M{\Omega}$ and the mean insulation resistance within the confidence interval reduced to $9.21M{\Omega}$. In the normal distribution analysis of 95% confidence interval, the value-P of the normal product was stable at 0.075 and AD(Anderson-Darling) statistic value was turned out to be 0.063, which is very normal, and the standard deviation was analyzed as 0.2586. The value P of the product completed the flammability test resulted in 0.005, the AD was 1.355 and the standard deviation reduced to 0.07908.

Study on the Relation Constant between OCR and Normalized Net Cone Tip Resistance (정규화 콘팁저항치와 OCR의 관계상수에 관한 연구)

  • Kim, Dae-Kyu
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.5
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    • pp.1814-1819
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    • 2010
  • The relation constant method between OCR and normalized net cone tip resistance has been widely used to estimate OCR value in practice. In this study, the method was analyzed for the soft soils in the Bukmyun area in Changwon city and the northwestern area in Incheon city. The relation constant value was estimated in the range of 0.28~0.33 for the Bukmyun area in Changwon city and 0.49~0.6 for the northwestern area in Incheon city. The value was max. 90% larger than it from the foreign previous studies. This is not the conservative result so the previous methods should be used with great caution of determining the constant value.

Resistivity Analysis of Model Block for Using of Structure Grounding Electrode (구조체접지극 활용을 위한 모형블록의 저항률 분석)

  • Kim, Sung-Sam;Jeong, Man-Gil;Choi, Jong-Kyu;Koh, Hee-Seog
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.21 no.2
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    • pp.40-45
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    • 2007
  • This study analyzed the resistivity characteristic of model block to make the good use of structure grounding and substitution grounding electrode base of building. After making the model block of mortar and concrete block, it measured resistivity in hydrous condition and dry condition and compared with the blocks that is mixed earth resistance lowering agent to decrease resistivity. The resistance value of block accepted much influence by block resistivity. When the block resistivity was same or similar value, the value of soil resistivity has occurred as different as the value of grounding resistance.