• Title/Summary/Keyword: Research and Development Department

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Tuning for Temperature Coefficient of Resistance Through Continuous Compositional Spread Sputtering Method (연속 조성 확산 증착 방법을 통한 저항 온도 계수의 튜닝)

  • Ji-Hun Park;Jeong-Woo Sun;Woo-Jin Choi;Sang-Joon Jin;Jin-Hwan Kim;Dong-Ho Jeon;Saeng-Soo Yun;Jae-Il Chun;Jin-Ju Lim;Wook Jo
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.37 no.3
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    • pp.323-327
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    • 2024
  • The low-temperature coefficient of resistance (TCR) is a crucial factor in the development of space-grade resistors for temperature stability. Consequently, extensive research is underway to achieve zero TCR. In this study, resistors were deposited by co-sputtering nickel-chromium-based composite compositions, metals showing positive TCR, with SiO2, introducing negative TCR components. It was observed that achieving zero TCR is feasible by adjusting the proportion of negative TCR components in the deposited thin film resistors within certain compositions. Additionally, the correlation between TCR and deposition conditions, such as sputtering power, Ar pressure, and surface roughness, was investigated. We anticipate that these findings will contribute to the study of resistors with very low TCR, thereby enhancing the reliability of space-level resistors operating under high temperatures.

Single-phase Resonant Inverter using SiC Power Modules for a Compact High-Voltage Capacitive Coupled Plasma Power Supply

  • Tu, Vo Nguyen Qui;Choi, Hyunchul;Kim, Youngwoo;Lee, Changhee;Yoo, Hyoyol
    • Proceedings of the KIPE Conference
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    • 2014.11a
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    • pp.85-86
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    • 2014
  • The paper presents a power supply of atmospheric-pressure plasma reactor based on SiC (Silicon Carbide) MOSFET resonant inverter. Thanks to the capacitive characteristic of capacitive coupling plasma reactor type, the LC series resonant inverter had been applied to take advantages of this topology with the implementation of SiC MOSFET power modules as switching power devices. Designation of gate driver for SiC MOSFET had been introduced by this paper. The 5kVp, 5kW power supply had also been verified by experimental results.

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Exploring the experience of developing COVID-19 vaccines in Iran

  • Mostafa Ghanei;Ali Mohabattalab;Kiarash Fartash;Narjes Kolahchi;Alireza Khakdaman;Hooman Kaghazian;Abolfazl Bagheri
    • Clinical and Experimental Vaccine Research
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    • v.12 no.1
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    • pp.1-12
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    • 2023
  • Widespread public vaccination is one of the effective mechanisms to ensure the health and prevent deaths in societies. The coronavirus disease 2019 (COVID-19) vaccine is a stark instance in this regard. Vaccine development is a complex process requiring firm-level capabilities, various infrastructures, long-term planning, and stable and efficient policies. Due to the global demand for vaccines during the pandemic, the national capability to produce vaccines is critical. To this end, the current paper investigates influential factors, at the firm- and policylevel, in the COVID-19 vaccine development process in Iran. By adopting a qualitative research method and conducting 17 semi-structured interviews and analyzing policy documents, news, and reports, we extracted internal and external factors affecting the success and failure of a vaccine development project. We also discuss the characteristics of the vaccine ecosystem and the gradual maturity of policies. This paper draws lessons for vaccine development in developing countries at both firm and policy levels.

High Efficiency Binding Aptamers for a Wide Range of Bacterial Sepsis Agents

  • Graziani, Ana Claudia;Stets, Maria Isabel;Lopes, Ana Luisa Kalb;Schluga, Pedro Henrique Caires;Marton, Soledad;Ferreira, Ieda Mendes;de Andrade, Antero Silva Ribeiro;Krieger, Marco Aurelio;Cardoso, Josiane
    • Journal of Microbiology and Biotechnology
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    • v.27 no.4
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    • pp.838-843
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    • 2017
  • Sepsis is a major health problem worldwide, with an extremely high rate of morbidity and mortality, partly due to delayed diagnosis during early disease. Currently, sepsis diagnosis requires bacterial culturing of blood samples over several days, whereas PCR-based molecular diagnosis methods are faster but lack sensitivity. The use of biosensors containing nucleic acid aptamers that bind targets with high affinity and specificity could accelerate sepsis diagnosis. Previously, we used the systematic evolution of ligands by exponential enrichment technique to develop the aptamers Antibac1 and Antibac2, targeting the ubiquitous bacterial peptidoglycan. Here, we show that these aptamers bind to four gram-positive and seven gram-negative bacterial sepsis agents with high binding efficiency. Thus, these aptamers could be used in combination as biological recognition elements in the development of biosensors that are an alternative to rapid bacteria detection, since they could provide culture and amplification-free tests for rapid clinical sepsis diagnosis.

A comparison of antioxidant activity of Korean White and Red Ginsengs on H2O2-induced oxidative stress in HepG2 hepatoma cells

  • Sohn, Sang-Hyun;Kim, Si-Kwan;Kim, Young-Ock;Kim, Hyung-Don;Shin, Yu-Su;Yang, Seung-Ok;Kim, Seung-Yu;Lee, Sang-Won
    • Journal of Ginseng Research
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    • v.37 no.4
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    • pp.442-450
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    • 2013
  • The aim of this study was to determine and compare the preventive effect of Korean White Ginseng and Red Ginseng on oxidative stress in $H_2O_2$-treated HepG2 cells. The roots of ginseng were extracted with 70% methanol and partitioned with butanol to obtain saponin fractions, which have been known as bioactive constituents of ginseng. 2',7'-Dichlorofluorescein diacetate (DCF-DA) assay and malondialdehyde (MDA) content were measured for evaluating intracellular reactive oxygen species (ROS) generation. Also, mRNA expressions and activities of antioxidant enzymes were analyzed to determine the antioxidant activity of saponin or non-saponin fractions of ginsengs. According to DCF-DA assay, $H_2O_2$-induced MDA release and ROS generation were significantly reduced by treatment with saponin fractions of white and red ginseng roots. Also, saponin fractions increased effectively intracellular antioxidant enzyme activities including catalase, glutathione peroxidase and superoxide dismutase in $H_2O_2$-treated HepG2 hepatoma cells. In general, red ginseng was more effective than white ginseng for reducing oxidative stress. These results indicate that administration of red ginseng may certainly contribute relatively stronger than white ginseng to prevent from damaging liver function by oxidative stress.

Design of Underwater Ad-hoc Communication Protocol for Underwater Acoustic Networks

  • Yun, Chang-Ho;Cho, A-Ra;Kim, Seung-Geun;Park, Jong-Won;Choi, Young-Chol;Lim, Yong-Kon
    • Journal of information and communication convergence engineering
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    • v.8 no.1
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    • pp.6-12
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    • 2010
  • In this paper a cross layer protocol, referred to as an underwater ad-hoc communication (UAC) protocol, is proposed for underwater acoustic networks (UANets). An underwater node (UN), which tries to transfer data to another UN or a buoy in ad-hoc manner, can access channel as well as determine routing path by employing the UAC protocol. The channel access, route determination, and reliable data transfer are designed being adaptive to underwater environments. In addition, we propose both UN and packet architectures in order to efficiently implement the UAC protocol for UANets.