• The Korean Society of Law and Medicine
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• v.12 no.1
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• pp.99-131
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• 2011

To strengthen the protection of human research subjects and human materials, the Korean Ministry of Health and welfare proposed the amendment bill of Bioethics and Safety Law(2010) to the Congress. It includes so many meaningful clauses. According to the bill, the scope that this act shall apply will be expended to the research involving human subjects and human materials. In the bill, there are the principles of this act; the protection of the life, health, and dignity of the human subjects, the obtaining of the adequate informed consent, the protection of the human subject's information confidentiality and the human subject's privacy, the assessment and minimizing of the risks involved and the guarantee of the safety for the human subjects, the preparation of the special protection program for the vulnerable human subjects, and so on. According to the bill, Institutional Bioethics Review Board(the same as Institutional Review Board) will be responsible for the auditing and monitoring on the research that was approved by IBRB, conducting the education program for the researchers, IBRB members and administrative staffs, preparing of the special protection program for the vulnerable human subjects, and forming the guidelines for the researchers as well as the review of the research protocols. And the State and local governments shall take necessary measures to support the expending of the social infrastructure. In addition to, IBRB will have to be assessed and to be gained the accreditation by the Korean Ministry of Health and welfare. So, if Bioethics and Safety Law is amended, it will contribute enormously to enhance the level of the human research subjects protection. Also, if this Law is amended, IBRB will play a major role for the conduct of the ethically, scientifically, and legally proper research. But now, as a matter of fact, the capability of IBRB members and IBRB office members is not enough to charge of this role because some people and some organizations does not know the importance of IBRB exactly. In spite of, IBRB shall be able to this role to protect the human subjects and to develop the level of the research On the international level. Therefore, the State, local governments and the Organization shall back up the administrative and financial terms of the IRB and IRB Office.

• Imaging Science in Dentistry
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• v.40 no.1
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• pp.25-32
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• 2010

Purpose : This study was designed to evaluate the efficacy and utility of panoramic radiograph for the improvement of the periodic oral examinations. Materials and Methods : Clinical examinations and panoramic examinations were done for the 242 subjects of oral examinations. The results of panoramic radiograph interpretation were compared with the clinical findings. Two questionnaires were created. One was carried out before the panoramic examination and the other done afterwards, to find out the subjects' cognition and satisfaction for the clinical and panoramic examinations. Results : 1. Panoramic findings showed a higher detection rate of 31.9% for periodontal diseases, and 23.1% for dental caries than clinical findings. 2. The additional abnormalities detected through panoramic examinations were impacted tooth in 81 subjects (33.6%), maxillary sinus abnormalities in 28 subjects (11.6%), condylar abnormalities in 5 subjects (2.1%), congenital and acquired dental anormalies in 59 subjects (24.5%), and other miscellaneous abnormalities in 34 subjects (14.1%). 3. 164 subjects (67.8%) were satisfied with the current periodic oral examination, and 75 subjects (31.1%) hoped for better accuracy. 4. In the first and second questionnaire, 154 subjects (67.0%) and 163 subjects (70.6%) responded respectively that panoramic examination was necessary, and 193 subjects (83.2%) responded that it actually helped. Conclusion : The panoramic examination was revealed to improve the effectiveness of the periodic oral examination and to increase the satisfaction of the subjects of examination.

• Journal of Korean Public Health Nursing
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• v.22 no.2
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• pp.255-265
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• 2008

Purpose: The principal objective of this study was to assess the topics and research methods of smoking-related research and to suggest future research directions. Methods: The subjects of this study were smoking research articles supported by the National Health Promotion Funds from 1998 to 2007. A total of 41 articles were selected and analyzed from 1999 to 2005 using the frameworks such as topics, subjects contents, subjects, research field, and research design. Results: The most frequent topic of smoking-related research was the development & evaluation of educational programs for smoking prevention and smoking cessation (34.1%). The majority of the research subjects were adults (42.2%) and adolescents (35.9%). 31.7% of the total research researches was conducted at the nationwide population level. The most popular research design was the descriptive study (36.6%) in the non-experimental studies and nonequivalent control group pretest-posttest design(19.5%) in the experimental study studies. Conclusion: The topics of smoking research should be planned under governmental strategies for decreasing to a 30% reduction in of smoking rates, as established in the 2010 Health Plan. With regard to the methodological aspects, longitudinal and nationwide research was first required so that we could plan an evidence-based program for smoking prevention and smoking cessation.

• Progress in Superconductivity
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• v.5 no.1
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• pp.38-44
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• 2003

The aim of this study is to confirm clinical usefulness of magnetocardiogram (MCG) by analyzing MCG data of health subjects and patients with Wolff-Parkinson-White (WPW) syndrome and dilated cardiomyopathy (DCM). Measurement of MCG signals was done with a home-made 40-channel SQUID system. MCG signals of 30 healthy subjects were measured as the reference of MCG signals. Among the DCM patients, 7 patients showed abnormal the direction of T wave vector. For a WPW syndrome patient, we measured the MCG signals before and after the surgery. and compared the difference. From the measured magnetic field distribution, current vector map was obtained to show the myocardium current activity. By comparing the MCG signals and current maps, we showed the differences in the analysis results between the healthy subjects and patients with heart diseases.

• The Korean Journal of Physiology and Pharmacology
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• v.27 no.1
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• pp.49-59
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• 2023

Metabolic syndrome (MetS) involves multi-factorial conditions linked to an elevated risk of type 2 diabetes mellitus and cardiovascular disease. Pre-metabolic syndrome (pre-MetS) possesses two MetS components but does not meet the MetS diagnostic criteria. Although cardiac autonomic derangements are evident in MetS, there is little information on their status in pre-MetS subjects. In this study, we sought to examine cardiac autonomic functions in pre-MetS and to determine which MetS component is more responsible for impaired cardiac autonomic functions. A total of 182 subjects were recruited and divided into healthy controls (n=89) and pre-MetS subjects (n=93) based on inclusion and exclusion criteria. We performed biochemical profiles on fasting blood samples to detect pre-MetS. Using standardized protocols, we evaluated anthropometric data, body composition, baroreflex sensitivity (BRS), heart rate variability (HRV), and autonomic function tests (AFTs). We further examined these parameters in pre-MetS subjects for each MetS component. Compared to healthy controls, we observed a significant cardiac autonomic dysfunction (CAD) through reduced BRS, lower overall HRV, and altered AFT parameters in pre-MetS subjects, accompanied by markedly varied anthropometric, clinical and biochemical parameters. Furthermore, all examined BRS, HRV, and AFT parameters exhibited an abnormal trend and significant correlation toward hyperglycemia. This study demonstrates CAD in pre-MetS subjects with reduced BRS, lower overall HRV, and altered AFT parameters. Hyperglycemia was considered an independent determinant of alterations in all the examined BRS, HRV, and AFT parameters. Thus, hyperglycemia may contribute to CAD in pre-MetS subjects before progressing to MetS.

• Korean journal of food and cookery science
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• v.21 no.6 s.90
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• pp.800-812
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• 2005

This study selected and classified the representative foods for diversifying Korean traditional foods in the globa1 market and derived the superior factor of each food by consumer survey (n=744). The superiority of Korean traditional foods was generally recognized as being in the order of 'Nutritional value' > 'Dietary culture' > 'Material' > 'Taste.' Kimchi, Tteok/Hangwa, and grilled foods were regarded as potent Korean traditional foods for global consumers. The survey about the superior factors of representative Korean traditional foods produced the following results. The superior factor of Bibimbap, Mandu, Jangachi, Joeotgal, Namul muchim Salad, Naengchae, and Ganjang was 'Variety of material or cuisine', that of Bap, Jut Samguetang, Seolleongtang, Kimchi, Doenjang, and Sikcho was 'Nutritional value', that of Naengmyeon, Kalguksu, Bulgogi, Pyeonyuk, Jeongol, Gochujang, Tteot and Sjkhae/Sujeonggwa was Taste', and that of Hangwa, Hwachae, Gujulpan, and Sinsunro was 'Appearance'. The superior factors of representative Korean traditional foods showed the following differences by age and gender, The superior factor in Mandu was 'Taste' by the subjects aged below 30 but 'Variety' by the subjects aged above 30; that in Pyeonyuk and Jeongol was 'Variety' in 31-40 year olds and those aged above 51, while it was 'Taste' in others. The superior factor of Kimchi was 'Nutritional value' by the subjects aged below 40,'Taste'in 41-50 year. olds, and 'Variety' by the subjects aged above 50, that of Namul muchim was 'Nutritional value' by the subjects aged below 20 and 'Variety'by the subjects aged above 20, and that of Naengchae was' Taste'by the subjects aged below 20 and 'Variety' by the subjects aged above 20. The superior factor of Gochujang was 'Taste' by the subjects aged below 50 and 'Variety 'by the subjects aged above 50, that of Ganjang was 'Variety' by the subjects aged below 30 and 'Taste' by the subjects aged above 30, that of Sikcho was 'Variety' by the subjects aged below 30 and 'Nutritional value' by the sutjects aged above 30. The superior factor of Doenjang was 'Nuttritional value' in all ages. The superior factors of Hangwa and Sikhae/Sujeonggwa were 'Appearance' and 'Taste' in all ages, and that of Hwachae was 'Taste' by the subjects aged below 30 and' Appearance' by the subjects aged above 30. The perception by gender was statistically differed for traditional foods such as Bap, Bibimbap, Kalguksu, Bulgogi, Pyeonyuk Jangachi, Gochujang, Ganjang, Sikhae/Sujeonggwa, Hwachae, and Gujulpan.

• The Korean Journal of Physiology
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• v.10 no.2
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• pp.29-37
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• 1976

Effect of furosemide administration on glucose tolerance, insulin-and HGH response following parenteral glucose loading was studied in healthy subjects. Effects of potassium or calcium on the furosemide induced changes were also observed in the same subjects. Furosemide administration resulted in a considerable reduction in the magnitude and duration of insulin response although no obvious changes were observed in glucose disappearance from the circulation. Oral potassium or calcium supplement to the furosemide treated subjects showed a reversion toward normal of the insulin response. The author suggested that a decreased endogenous insulin production resulting from the potassium and/or calcium depletion is responsible for the changes observed. In those subjects who receive parenteral nutrition if administration of furosemide is essential, it should be supplemented by potassium and/or calcium.

• Journal of Nutrition and Health
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• v.14 no.3
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• pp.117-123
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• 1981

The lipid composition of total serum lipids were investigated by latroscan TH-10 TLC analyzer in 69 healthy subjects and 62 patients with hypercholesterolemia. Total serum lipids level in healthy subjects was higher in females than males. There was a increase in total serum lipids level with increasing total serum cholesterol level in patients with hypercholesterolemia, regardless sex. Total serum lipids obtained from healthy subjects and patients with hypercholesterolemia were separated into phospholipids, free cholesterol, free fatty acids, triglycerides and cholesterol esters. Increasing the level of total serum cholesterol in the patients resulted in a decrease in the level of phospholipids, which was a major lipid fraction, indicating that HDL level in the patients was also decreased. However, cholesterol esters, triglycerides and free cholesterol levels in the patients were higher than those found in healthy subjects. The FC/CE ratio for male patients was lower than for healthy males, while in female patients, this ratio was similar to that observed in healthy females.

• The Research Journal of the Costume Culture
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• v.12 no.1
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• pp.151-167
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• 2004

The purpose of this study was to find out comparison of preference style and wearing style of jacket by body perception and satisfaction. This research was done by a survey method. Descriptive Statistics, t-test, Pearson's Correlation, Coefficients MANOVA, Two-Way ANOVA and Duncan's test were used for data analysis. The results of this study are as follows. 1) The subjects were less satisfied with larger or thicker girth of upper body. The subjects were less satisfied with thicker upper arm, lower arm, waist and lower abdomen. The subjects were less satisfied with larger or thicker girth of lower body. The subjects were less satisfied with thicker hips, thighs, calves, ankles, and longer crotch length. 2) The subjects with the highest dissatisfaction about neck thickness and length prefer jacket with collar but wear jacket without cellar. The subjects with the smallest bust wear jacket with short lapel. The subjects with wider shoulder wear jacket with narrower shoulder width. The subjects with more dissatisfaction about shoulder incline wear raglan sleeve jacket. The subjects with wider hips wear hip line length jacket.

• The Research Journal of the Costume Culture
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• v.12 no.4
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• pp.511-528
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• 2004

The purpose of this study was to find out comparison of preference style and wearing style of pants and skirt by body perception and satisfaction. This research was done by a survey method. Descriptive Statistics, Coefficients MANOVA, Two-Way ANOVA, t-test and Duncan＇s test were used for data analysis. The results of this study are as follows. 1) The subjects with the highest dissatisfaction about waist girth prefer high waist pants. The subjects with longer waist wear high waist pants. The subjects with wider hips wear narrow down pants. The subjects with the thickest thighs prefer narrow pants but wear narrow down pants. The subjects with the highest dissatisfaction about calf thickness prefer narrow pants but wear wide pants. The subjects with the highest satisfaction about leg length prefer and wear calf length pants. The subjects with the thinnest calves prefer and wear tight pants. 2) The subjects with the thickest thighs prefer straight skirt but wear narrow down skirt. The subjects with the highest dissatisfaction about thigh thickness wear A-line skirt.