• Journal of the Korean Society of Industry Convergence
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• v.25 no.1
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• pp.27-35
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• 2022

A systematic support system that develops technology support policies for SMEs (Small and Medium sized Enterprises) and solves technical problems faced by SMEs will increase the productivity and competitiveness of SMEs. To this end, it is necessary to identify the types and level of technology required for SMEs, and to find ways to utilize the technologies possessed by government-funded research institutes leading technology development. It is important to develop a new production technology and to establish a cooperation system between SMEs and government- funded research institutes to solve various pending problems.

• 대한예방의학회:학술대회논문집
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• 1995.10a
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• pp.281-282
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• 1995

• 대한예방의학회:학술대회논문집
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• 1995.10a
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• pp.73-74
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• 1995

• Proceedings of the Korea Technology Innovation Society Conference
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• 2000.11a
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• pp.357-377
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• 2000

This paper seeks to search a improved evaluation system of government sponsored research institutes(GSRI) as a knowledge system It begins with a brief review of the theory of knowledge and knowledge system This is followed by a search of the desirable conditions of the evaluation system of GSRI as a knowledge system These conditions presented are applied within the context of the current evaluation system of GSRI. Finally conclusions are drawn and directions for improvement of the system are outlined.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.228.1-228.1
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• 2002

Hypoxia in solid tumors is known to contribute to intrinsic chemoresistance. Tirapazamine(TPZ). a hypoxia-selective cytotoxin. showed synergism with radiation or cytotoxic agents. Paclitaxel(PTX) is a highly active anti-cancer agent against Non small cell lung cancer(NSCLC), however. due to poor penetration into central hypoxic region of tumor tissue. combination with TPZ has been suggested to enhance its efficacy. (omitted)

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.244.1-244.1
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• 2002

Cyclooxygenase-2 ( COX-2 ) is an inducible enzyme which produces prostanoids by various stimuli. Overexpression of COX-2 in many tumor types indicates its association with tumor progression, which has been a promising target for chemoprevention and chemomodulation. We studied conc- and time-dependency of COX-2 inhibition, growth inhibition, and cell cycle arrest induced by celecoxib, a selective COX-2 inhibitor, in human non-small cell lung cancer (NSCLC) A549 cells. (omitted)

• Journal of Marine Bioscience and Biotechnology
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• v.1 no.1
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• pp.22-33
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• 2006

This paper deals mainly with chemical and biological investigations, recently effected in the authors' laboratory, of Chinese tropical marine plants and invertebrates on three topics: 1) an unusual macrocyclic polydisulfide from the Chinese mangrove Bruguiera gymnorrhiza; 2) polyhydroxylpolyene compounds from marine dinoflagellate Amphidinium sp.; 3) two new series of uncommon steroids from marine in vertebrates.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.227.2-228
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• 2002

ZD1839 is a new anticancer agent which selectively inhibits EGFR tyrosine kinase. Oxaliplatin (LOHP), 5-FU (FU), and paclitaxel (PTX) have shown to be highly active against the gastric carcinomas. and ZD1839 is considered as a good candidate for the treatment of gastric cancers when combined with cytotoxic agents. In this study, we evaluated the antitumor effects of these agents in SNU-l human gastric cancer cells either alone or when given as a doublet. (omitted)

• BMB Reports
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• v.50 no.4
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• pp.164-174
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• 2017

Mitochondria are cytosolic organelles essential for generating energy and maintaining cell homeostasis. Despite their critical function, the handful of proteins expressed by the mitochondrial genome is insufficient to maintain mitochondrial structure or activity. Accordingly, mitochondrial metabolism is fully dependent on factors encoded by the nuclear DNA, including many proteins synthesized in the cytosol and imported into mitochondria via established mechanisms. However, there is growing evidence that mammalian mitochondria can also import cytosolic noncoding RNA via poorly understood processes. Here, we summarize our knowledge of mitochondrial RNA, discuss recent progress in understanding the molecular mechanisms and functional impact of RNA import into mitochondria, and identify rising challenges and opportunities in this rapidly evolving field.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.10a
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• pp.587-590
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• 2017

In this paper, we investigate the current status and problems of information security in government - funded research institutes, where the frequency of cyber - infringement threats is increasing, and emphasize the importance of information security. do. To this end, we will contribute to the establishment of a stable information security infrastructure for government-funded research institutes in the future by identifying problems and proposing improvement measures based on data related to information security such as information security policies, organizations, and budgets of government-funded research institutes.