• Title/Summary/Keyword: Research Facility

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A Study on the Community Facility Design Convertible to Refuge in case of Emergency (비상시 대피시설로 전환가능한 주민시설 디자인에 관한 연구)

  • Kim, Hee-Kyo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.4
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    • pp.2503-2510
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    • 2014
  • This study chiefly aims to find out the efficient ways of designing community facility convertible to refuge in case of emergency. In order to reach this goal, this study analyzed (1) definition of terminologies regarding disaster and refuge space, (2)present situation of regarding acts and standards, (3)function and spatial specialties of existing community facilities. Besides, in order to clarify the efficient design methods of 'function-convertible-type' community facility, this study executes archival research on (1)spatial requirements, (2)methods of designing futuristic community facility. When making design directives of community facilities, it is important to consider (1)vertical integration of rescue related function, (2)spatial division and architectural installation concerning privacy, (3)proper layout of locker room, shower room, toilet, etc. (4)appropriate size of unit space. It is desirable to execute the refuge function with minimum psychological anxiety in case of disaster through design guideline for 'function-convertible-type' community facility.

Characterization of Bacillus anthracis proteases through protein-protein interaction: an in silico study of anthrax pathogenicity

  • Banerjee, Amrita;Pal, Shilpee;Paul, Tanmay;Mondal, Keshab Chandra;Pati, Bikash Ranjan;Sen, Arnab;Mohapatra, Pradeep Kumar Das
    • CELLMED
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    • v.4 no.1
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    • pp.6.1-6.12
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    • 2014
  • Anthrax is the deadly disease for human being caused by Bacillus anthracis. Instantaneous research work on the mode of infection of the organism revealed that different proteases are involved in different steps of pathogenesis. Present study reports the in silico characterization and the detection of pathogenic proteases involved in anthrax infection through protein-protein interaction. A total of 13 acid, 9 neutral, and 1 alkaline protease of Bacillus anthracis were selected for analysing the physicochemical parameter, the protein superfamily and family search, multiple sequence alignment, phylogenetic tree construction, protein-protein interactions and motif finding. Among the 13 acid proteases, 10 were found as extracellular enzymes that interact with immune inhibitor A (InhA) and help the organism to cross the blood brain barrier during the process of infection. Multiple sequence alignment of above acid proteases revealed the position 368, 489, and 498-contained 100% conserved amino acids which could be used to deactivate the protease. Among the groups analyzed, only acid protease were found to interact with InhA, which indicated that metalloproteases of acid protease group have the capability to develop pathogenesis during B. anthracis infection. Deactivation of conserved amino acid position of germination protease can stop the sporulation and germination of B anthracis cell. The detailed interaction study of neutral and alkaline proteases could also be helpful to design the interaction network for the better understanding of anthrax disease.

Using Cost-Benefit Analysis for a Feasibility Study on Constructing a Storage Facility in the Small River Basin (비용편익 분석을 통한 소하천유역의 저류조 설치 타당성 분석연구)

  • Seo, Se-Deok;Lee, Seung-Wook;Park, Hyung-Keun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.36 no.1
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    • pp.135-141
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    • 2016
  • This study aims to analyze the feasibility of installing a storage facility and make recommendations based on a cost-benefit analysis regarding the installation of a storage facility capable of preventing both floods and droughts. The capacity and installation costs are specified for the storage facility necessary to prevent floods, and a cost-benefit analysis is conducted by calculating the costs and benefits for each cost or benefit factor such as loss amounts, recovery costs, and drought prevention. The information can be used as the basic data for suggesting the feasibility of installing a multipurpose storage facility capable of preventing floods and droughts simultaneously. Also, this study expects to utilize its detailed results in a number of different ways including the prediction of loss amounts from natural disasters.

A Study on System of Mental Healthcare Service in Germany (독일 정신보건의료서비스체계에 관한 연구)

  • Moon, Ha Ni;Noh, Jai Sung;Chai, Choul Gyun
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.20 no.3
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    • pp.17-25
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    • 2014
  • Purpose: Mental health facilities are facing a new social environment. To provide appropriate patient care environment, mental health and mental healthcare is changing the paradigm. In this situation, this study research and analysis mental healthcare service system and mental healthcare facility in Germany. The reason is that Germany has cosistently been building mental healthcare service system and mental healthcare facility for patient. Therefore, it aims to suggest a fundamental resource for amental healthcare service system and mental healthcare facility for mental healtn. Methods: This study was conducted literature researches and field studies. Literature researches for mental healthcare service system and facilities. Field study is to identify the characteristic and configuration of mental healtncare facilities. Results: Findings of this study can be summerrized inth three points. First, In Germany, Mental healthcare facility is critical environment in the community. And, the facilities are being turned into reasonable and alternative environment. Second, Facilities of Mental healthcare and service system designed by various level and configurations that can be providing places for people with mental problems. Third, Mental healthcare facilities consist of healing environment for patient. Implications: The future study on finding of the specific environment planning citeria in mental healthcare facility on the basis of findings of present study.

A Study on the Image Evaluation and Morphological Elements of Buildings In the University Campus (대학캠퍼스 건축물의 형태적 요소 및 이미지평가에 관한 연구)

  • Kim, Cheon-Il;Kim, Ick-Hwan
    • The Journal of Sustainable Design and Educational Environment Research
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    • v.12 no.2
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    • pp.1-10
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    • 2013
  • This study evaluates the relationship among the evaluation structure of morphological elements, the satisfaction on exterior elements, and the image evaluation for the campus landmarks by campus type. The investigation results are summarized as follows. 1) The university headquarter was nominated as the university landmark, and the main reason for the nomination was the building's historic and locational value. 2) Of the morphological elements of the campus landmark, 'proportion and balance' and 'harmony and order' were deemed important, while 'diversity' was deemed less important. 3) For the satisfaction on the facility's exterior elements, the evaluation structure was different for each university. However, the factor of 'location of the facility' was deemed the biggest factor for satisfaction for all universities, while the facility's 'color and material' were found to be the most dissatisfying factors. 4) The image evaluation on the facility was different for each university. Although there was a strong skeptical image about 'liveliness', there was a very positive image about 'elegance' and 'scale'. 5) On the relationship between the satisfaction on exterior elements and the image evaluation, there was a different evaluation structure for each university. 'Facility's color and exterior material' were the main elements which improved the overall image of the facility. Thus, the study results strongly suggest that an important task is to determine the maintenance direction through the emphasis on the relationship between exterior elements and image satisfaction for each university.

Preliminary Design of Test Facility for 75 tonf Class Liquid Rocket Engine Combustor (75톤급 액체로켓엔진 연소기 시험설비 기본설계)

  • Lim, Byoung-Jik;Kim, Jong-Gyu;Lee, Kwang-Jin;Kim, Mun-Ki;Ahn, Kyu-Bok;Kang, Dong-Hyuk;Seo, Seong-Hyeon;Han, Yeong-Min;Choi, Hwan-Seok
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2009.11a
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    • pp.353-358
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    • 2009
  • For the successful development of 75 tonf class liquid rocket engine, a plenty of tests on each engine component has to be performed and this is equally true for a combustor. However the test facility which is in operation at Korea Aerospace Research Institute lacks its capacity to perform fire tests of a 75 tonf class combustor at its nominal thrust. Since the test facility has to be ready prior to the start of development tests, it is very urgent to establish the test facility. The preliminary design of a test facility for a 75 tonf class combustor which was performed according to the urgent necessity is described in the paper.

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Development of a Probabilistic Safety Assessment Framework for an Interim Dry Storage Facility Subjected to an Aircraft Crash Using Best-Estimate Structural Analysis

  • Almomani, Belal;Jang, Dongchan;Lee, Sanghoon;Kang, Hyun Gook
    • Nuclear Engineering and Technology
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    • v.49 no.2
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    • pp.411-425
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    • 2017
  • Using a probabilistic safety assessment, a risk evaluation framework for an aircraft crash into an interim spent fuel storage facility is presented. Damage evaluation of a detailed generic cask model in a simplified building structure under an aircraft impact is discussed through a numerical structural analysis and an analytical fragility assessment. Sequences of the impact scenario are shown in a developed event tree, with uncertainties considered in the impact analysis and failure probabilities calculated. To evaluate the influence of parameters relevant to design safety, risks are estimated for three specification levels of cask and storage facility structures. The proposed assessment procedure includes the determination of the loading parameters, reference impact scenario, structural response analyses of facility walls, cask containment, and fuel assemblies, and a radiological consequence analysis with dose-risk estimation. The risk results for the proposed scenario in this study are expected to be small relative to those of design basis accidents for best-estimated conservative values. The importance of this framework is seen in its flexibility to evaluate the capability of the facility to withstand an aircraft impact and in its ability to anticipate potential realistic risks; the framework also provides insight into epistemic uncertainty in the available data and into the sensitivity of the design parameters for future research.

Study on the Decommissioning of Small Nuclear Facility through Analyzing Foreign Decommissioning Practices (국외 해체 사례 분석을 통한 국내 소규모 방사선이용시설 해체에 관한 연구)

  • Kwon, Dayeong;Kim, Yongmin
    • Journal of the Korean Society of Radiology
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    • v.9 no.3
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    • pp.125-130
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    • 2015
  • RI & RG are used in various field such as medical field, industrial field, agricultural and food&life field. The number of small nuclear facilities is on the increase. We need to take an interest in decommissioning of small nuclear facility and predict the occurring problem from facility decommissioning. Because of the relatively low radiation risk, the preparation of the small nuclear facility dismantling is often neglected. As the accident in Goiania, Brazil showed, the impact of the decommissioning of small nuclear facilities is not less than the large nuclear facilities although it may seem dangerless. Therefore, we analyzed the each institutional characteristics of the decommissioning of small nuclear facilities through foreign case study on this research. Also, we proposed several considerations on decommissioning such as reuse of facility and source, lack of space, stakeholder involvement and failures of protection. Through these study, we tried to make guideline of the small nuclear facilities decommissioning.

Radiological Environment Investigation of Radioactive Waste Disposal Facility (방사성폐기물 처분시설 주변의 방사선환경조사)

  • Baek, Jeong-Seok;Jeong, Yeui-Young;Ahn, Sang-Bok;Kim, Wan
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.6 no.4
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    • pp.387-398
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    • 2008
  • To obtain base-line data in the low- and intermediate-level radioactive waste disposal facility, radiological environment investigation is required at least two years prior to the facility operation near the disposal facility. The investigation has been performed since January 2007 for the Wolsong LILW disposal center. In this paper, investigation procedure and detailed information obtained for six months in 2008 are described. Based on the current results, future investigation planning is also discussed for the radiological environment management of the disposal facility.

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Biosafety and Biosecurity Programme: Its Implementation, Requirements and Continuous Development at the Nanyang Technological University in Singapore

  • Tun, Tin;Preiser, Peter Rainer
    • Korean Journal of Clinical Laboratory Science
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    • v.50 no.2
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    • pp.77-84
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    • 2018
  • In Singapore, biosafety and biosecurity measures are controlled by the Biological Agents and Toxins Act (BATA) and other requirements by regulatory agencies. The law prohibits and otherwise regulates the possession, use, import, transhipment, transfer, and transportation of biological agents, inactivated biological agents, and toxins that are of public health concern. The law also defines the facility requirements for high risk biological agents and toxins. The containment facility (BSL 3) is a minimum requirement to handle biological agents that falls under Schedule 1 (Risk Group 3). The Nanyang Technological University School of Biological Sciences Biosafety Level 3 Facility (NTU-SBS BSL 3) was designed specifically for research involving potential hazardous biological materials. The facility requires yearly re-certification by an approved facility certifier to meet the local requirements and international biosafety standards for a containment facility in many instances. On the other hand, most NTU researchers conduct biological projects involving biological agents with low or moderate risk groups (Risk Groups 1 and 2 or biological agents described in schedule 3 and 4 of BATA) and GMOs, which need only a BSL 2 laboratory. BSL 2 laboratories are yet to be legally certified or registered in Singapore. Institutional Biosafety Committee (IBC) identifies the requirements; defines a minimum standard in the safe control of biological risks and registers all BSL 2 laboratories in the NTU. Therefore, under the guidance of the IBC, the University Biosafety and Biosecurity Programme includes the audit and certification program as a unique and an internal exercise to bring NTU biosafety to a higher level.