• 제목/요약/키워드: Research & Development Intensity

검색결과 734건 처리시간 0.028초

미세전류자극 강도가 흰쥐의 골관절염 회복에 미치는 영향 (The Effect of Microcurrent Stimulation Intensity on Osteoarthritis in Rat)

  • 진희경;박장성;김종만
    • 한국전문물리치료학회지
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    • 제18권1호
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    • pp.83-92
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    • 2011
  • Osteoarthritis is a degenerative joint disease and is led to physical disability. Yet the development of effective disease-modifying treatments has lagged. In this study, I examined the effect of physical therapeutic intervention through microcurrent stimulation and attempt to find which degree of intensity, either 25 ${\mu}A$ or 500 ${\mu}A$ with a regular 5 pps pulse, is more effective in the osteoarthritis. Osteoarthritis was induced with a mixture of 2% carrageenan and 2% kaolin in 26 male Sprague-Dawley rats. The mixture (0.1 $m{\ell}$) was injected into the intra-articular capsule of knee joint once a week for three weeks. Five animals did not show degenerative changes by radiological findings and excluded in the following experiment. Osteoarthritic animals were randomly divided into 3 groups ($n_1$, $n_2$, $n_3$=7/each): untreated, treated with 25 ${\mu}A$, treated with 500 ${\mu}A$. All experimental groups received microcurrent stimulation for four weeks (15 min/day, 5 days/week). The ethological inspection of foot print analysis on the walking corridor was accomplished every week. Histological preparations and immunohistochemical staining with insulin-like growth factor-1 were also done in the articular cartilages. All of these parameters were compared with those of osteoarthritic control group (n=7). The ethological inspection of foot print analysis revealed that changes of walking track (paw width) and stride length was significantly increased in both experimental groups. The better results were observed in experimental group treated with 25 ${\mu}A$ intensity without significance than group treated with 500 ${\mu}A$. Histological preparations disclosed that routine hyaline cartilage of articular surface were altered to fibrous cartilage in untreated group and experimental group treated with 500 ${\mu}A$ intensity. But a little changes were seen in experimental group treated with 25 ${\mu}A$ intensity. Immunolocalization of insulin-like growth factor-1 was simultaneously decreased according to the duration of osteoarthritis, and did not show significant difference among the groups. In this study discovered that the microcurrent stimulation, especially 25 ${\mu}A$ intensity, had a positive effect by the ethological inspection, histological and immunohistochemical stainings. These results suggest that microcurrent stimulation with low-intensity might be effective in the promotion of healing process for the osteoarthritis.

Comparison of PCCC and SCCC for an Optical CDMA System

  • Kim, Jin-Young
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 2000년도 하계종합학술대회 논문집(1)
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    • pp.181-184
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    • 2000
  • In this paper, performance of an optical CDMA system with PCCC and SCCC is simulated and compared. It is assumed that optical channel is an intensity modulated (IM) channel and direct-detection scheme is employed to detect the received optical signal. The modulation scheme used is pulse-position-modulation (PPM). The performance is evaluated in terms of bit error probability. From the simulation results, it is shown that turbo coding offers considerable coding gain with reasonable encoding/decoding complexity.

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농업용수 시험지구의 관측 및 물관리 특성 (Monitoring System and Irrigation Characteristics of Yi-dong Water District)

  • 김진택;이용직
    • 한국농공학회:학술대회논문집
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    • 한국농공학회 2002년도 학술발표회 발표논문집
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    • pp.13-16
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    • 2002
  • Operation of experimental site on the rural water is necessary to research on the effective development and management of agricultural water. Hydrological data on the watershed runoff, reservoir storage, irrigation and drainage are measured and accumulated. For the monitoring system of the experimental site, four rainfall gauging stations and twenty-six water level gauging stations are established and operated. Analysis of measured data are processed for rainfall amount and intensity, water level and discharge.

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The Resonance Frequency of Sound Channel in Shallow Water a Thermocline

  • Yan, Jin;Kim, Bong-Chae
    • The Journal of the Acoustical Society of Korea
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    • 제15권4E호
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    • pp.65-71
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    • 1996
  • In shallow water with a thermocline, the characteristics of sound propagation strongly depend on the signal frequency. When only one of the source and the receiver is above the themocline, it is known that the intensity of the received signal changes largely and almost periodically as the signal frequency varies. This is the so-called channel resonance. By using the ray-mode approach, the formula relating the resonance frequency and the sound speed profile is obtained, and the resonance phenomenon is analyzed. Also this analysis is verified by numerical calculation.

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Light Field 기술개발 동향 (Trends in the Technology Development of Light Field)

  • 전황수;한미경;장종현
    • 전자통신동향분석
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    • 제33권2호
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    • pp.56-63
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    • 2018
  • A light field (LF) is a field for expressing the intensity and direction of light reflected from a subject in a 3D space. Dual LF cameras are equipped in smart phones in Korea, mainly those by Samsung and LG. Lytro, Apple, Nvidia, MIT Media Lab, Magic Lip, and NHK are also developing LF camera technologies. LF displays are being researched by ETRI, Samsung Electronics, KIST, KAIST, SNU, MIT Media Lab, USC, HP, Apple, Microsoft, SeeReal, Musion Eyeliner, Dimenco, and Holografika.

국내 자본시장에서의 재벌 계열사들의 연구개발비 비중에 대한 재무적 실증분석 (Empirical Analyses on the Financial Profile of Korean Chaebols in Corporate Research & Development Intensity)

  • 김한준
    • 한국산학기술학회논문지
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    • 제20권4호
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    • pp.232-241
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    • 2019
  • 본 연구는 현대 재무관리 이론 상 전형적인 주제로서 현재까지도 지속적인 논의의 대상이 되는 국내 재벌그룹 소속 계열사들의 연구개발비 비중에 대한 재무적 결정요인들에 대한 분석이다. 실증 연구를 통한 분석 결과의 강건성 제고를 위하여 본 연구에서는 다양한 실증적 모형들이 응용되었다. 절대적 추정방법으로서 정적인 패널자료 모형, 토빗 모형 그리고 단계적 회귀 모형 등이 활용되었고, 상대적인 추정방법으로서 로짓, 프로빗 그리고 보완적 로그-로그 모형 등이 재벌소속 계열사와 그에 대한 상대 표본인 비재벌소속 계열사들의 재무적 결정요인의 차별성 규명을 위하여 응용되었다. 실증 분석 결과와 관련, 전년도의 연구개발비 비중, 시장가치 기준의 부채비율 그리고 기업규모 등이 첫 번째 가설에서 표본기업들의 연구개발비 비중에 대하여 통계적으로 유의한 재무적 결정요인으로서 판명되었으며, 후자의 상대적 추정모형 분석에서는 총 11개의 설명변수들 중, 대다수의 변수들이 통계적으로 유의한 것으로 검정되었다. 최근 국내 자본시장에서 요구하는 재벌기업들의 사회-경제적 기능면에서의 점진적 변화 가능성을 전제하여, 본 연구 결과는 재벌소속 계열사들의 적정 연구개발비 수준을 결정하기 위한 선행요인들의 재무적 분석에 기여할 수 있다고 판단된다.

프루브 길이에 따른 A5052 겹치기 마찰교반접합 특성 (Characteristics of Friction Stir Lap Welded A5052 with Probe Length)

  • 고영봉;강채원;최준웅;박경채
    • 한국표면공학회지
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    • 제42권6호
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    • pp.294-300
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    • 2009
  • The Friction Stir Welding (FSW) has mainly been used for making butt joints in Al alloys. The development of Friction Stir Lap Welding (FSLW) would expand the number of applications. In this study, for effective application on thin aluminum alloy lap joint, non-heat treatment A5052 alloys were joined by FSLW with the length of probe 2.3 mm and 3.0 mm. Investigating the characteristics of joint area showed the results were as below ; When the length of probe was 2.3 mm, good joint area was formed at all welding condition except for 600 rpm-700 mm/min. In the case of 3.0 mm probe length, there was formed good joint area without defects at 1500 rpm-100 mm/min. The width of joint area, position and size of defects were very important factors for FSLW, due to heat input and stirring intensity.

Development Behavior of Vaporizing Sprays from a High-Pressure Swirl Injector Using Exciplex Fluorescence Method

  • Choi, Dong-Seok;Kim, Duck-Jool;Hwang, Soon-Chul
    • Journal of Mechanical Science and Technology
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    • 제14권10호
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    • pp.1143-1150
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    • 2000
  • The effects of ambient conditions on vaporizing sprays from a high-pressure swirl injector were investigated by an exciplex fluorescence method. Dopants used were 2% fluorobenzene and 9% DEMA (diethyl-methyl-amine) in 89% solution of hexane by volume. In order to examine the behavior of liquid and vapor phases inside of vaporizing sprays, ambient temperatures and pressures similar to engine atmospheres were set. It was found that the ambient pressure had a significant effect on the axial growth of spray, while ambient temperature had a great influence on the radial growth. The spatial distribution of vapor phase at temperatures above 473K became wider than that of liquid phase after half of injection duration. From the analysis of the area ratio for each phase, the middle part (region II) in the divided region was the region which liquid and vapor phases intersect. For liquid phase, fluorescence-intensity ratio was greatly changed at lms after the start of injection. However, the ratio of vapor phase was nearly uniform in each divided region throughout the injection.

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한반도와 유럽에서 발생한 폭염의 종관기후학적 특성 비교 (A Synoptic and Climatological Comparison of Record-breaking Heat Waves in Korea and Europe)

  • 김지영;이대근
    • 대기
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    • 제18권4호
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    • pp.355-365
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    • 2008
  • Synoptic and climatological characteristics of heat waves over Korea and Europe as well as their biometeorological impacts were compared. In July of 1994, excess deaths of about 2,388 in the population of South Korea are estimated by the modified excess death calculation algorithm ofKysely (2004). The excess deaths correspond to the net mortality increase of 12.5% in July of 1994 if we compare the estimated value to the expected number of deaths in this month (i.e., about 19,171). The comparative study of heat waves in Korea and Europe shows that the record-breaking heat waves in both regions are closely associated with prolonged droughts. In particular, reduction of soil moisture, precipitation and cloud cover and enhancement of insolation during the drought periods are very likely to be related to the increase in the intensity and the duration ofheat waves. Climate models predict that the frequency, intensity, and duration of heat waves in the 21 st century will be greatly enhanced in both areas. In order to reduce the biometeorological and socioeconomic impacts due to heat waves, not only the development of heat-related mortality prediction model that can be widely applied to many climate regimes, but also studies on the climatological association between extreme temperatures and abnormal hydrological cycle are needed.

중성자선 실험 및 발암연구의 현황과 미래 (Current status of research on radionuclides used in nuclear mediccine)

  • 김희선
    • 동위원소회보
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    • 제21권3호
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    • pp.46-60
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    • 2006
  • In recent years the progress of nuclear medicine advanced dramatically in imaging and targeted radionuclide therapy is able to open op exciting perspectives as standard diagnostic and therapeutic modalities, complementing conventional modalities. Positron emission tomography/computed tomography (PET/CT) technology with FDG has been developed clinically in less than 10 years as a routine standard in oncological imaging, including a number of other fluorinated radiopharmaceuticals being evaluated for their ability to complement FDG. However, the limitation of FDG-PET such as non-specific uptake and its short half-life is not compatible with the time necessary for optimal tumour targeting. Therefore, a development of innovative positron-emitting radionuclides with half-lives longer than 10 h is needed. For therapeutic applications, the injection of higher activities is required to reach efficient adsorbed doses in radioresistant solid tumours, while limiting the irradiation of vital organs. In this application, the longer half-life of radiolsotopes are more fit well for radionuclide therapy. To achieve this, researches have to be carried in a largor spectrum of radionuclides for diagnosis and therapy. In the context of rapidly growing nuclear medicine and strong demanding innovative radionuclides, a high-energy (100 MeV), high-intensity (-mA) accelerator with proton (PEFF at KAFRI). will be operating in 2011. The priorities of PEFP will include supporting the nuclear medicine research community by providing those radionuclides with current limited availability by means of a high-energy, high-intensity accelerator.

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