• Proceedings of the Korean Nuclear Society Conference
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• 2005.05a
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• pp.43-44
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• 2005

• Molecular & Cellular Toxicology
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• v.5 no.4
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• pp.283-290
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• 2009

Differential gene expression profiling was performed in the hepatic tissue of marine medaka fish (Oryzias javanicus) after exposure to benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon (PAH), by heterologous hybridization using a medaka cDNA microarray. Thirty-eight differentially expressed candidate genes, of which 23 were induced and 15 repressed (P<0.01), were identified and found to be associated with cell cycle, development, endocrine/reproduction, immune, metabolism, nucleic acid/protein binding, signal transduction, or non-categorized. The presumptive physiological changes induced by BaP exposure were identified after considering the biological function of each gene candidate. The results obtained in this study will allow future studies to assess the molecular mechanisms of BaP toxicity and the development of a systems biology approach to the stress biology of organic chemicals.

• Journal of Marine Bioscience and Biotechnology
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• v.2 no.1
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• pp.34-39
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• 2007

Penaeidins are members of a special family of antimicrobial peptides existing in several species of shrimp and play a crucial role in the immunological defense of shrimp. In this study, we isolated and characterized one EST clone (penaeidin) from cDNA library of fleshy prawn Fenneropenaeus chinensis hemocytes. Amino acids sequence comparison and phylogenetic analysis with other known penaeidins revealed that our clone was completely identical to F. chinensis Penaeidin 3-2 (Accession no. ABC33920), which composed of 71 amino acids with a putative signal peptide (1-19) and a cysteine-rich domain (C-terminal part). The expression and distribution of Penaeidin 3-2 transcripts in shrimp were detected in hemocytes, hepatopancreas, and muscles, and that Penaeidin 3-2 was constitutively expressed mainly in hemocytes. The artificial infection of white spot syndrome virus to F. chinensis resulted in Penaeidin 3-2 mRNA up-regulation in hemocytes, suggesting that the possible role of Penaeidin 3-2 in host defense system of F. chinensis.

• Fisheries and Aquatic Sciences
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• v.17 no.3
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• pp.313-318
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• 2014

From 2008 to 2013, the mussel Mytilus galloprovincialis were collected from a major area of mussel production (Changseon area), which is a designated shellfish-cultivating area for export, located on the southern coast of Korea. The samples were analyzed for mercury (Hg) using a direct Hg analyzer and for other metals, such as cadmium (Cd), lead (Pb), arsenic (As), chromium, copper, nickel, and zinc, using inductively coupled plasma mass spectrometry. The concentrations and bioaccumulation of the heavy metals were determined, and a potential risk assessment was conducted to evaluate their hazards towards human consumption. The concentration and bioaccumulation ratio of Cd were the highest of the three hazardous metals (Cd, Pb, and Hg). The concentrations of hazardous metals in all samples were within the limits set by Korea and other countries. The estimated dietary intake (EDI) was compared to the provisional tolerable daily intake (PTDI) adopted by the Joint FAO/WHO Expert Committee on Food Additives and the U.S. Environmental Protection Agency. The EDIs of all heavy metals tested for mussel samples ranged from 0.01 to 4.99% of the PTDI; the highest value was measured for As. The hazard index (HI) can be used to assess the risk of heavy metal consumption associated with contaminated food. The HI for all samples was far less than 1.0, which indicates that the mussels produced in the Changseon area do not represent an appreciable hazard to humans and are fit for consumption.

• Journal of the Economic Geographical Society of Korea
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• v.15 no.4
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• pp.550-569
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• 2012

This paper studies the R&D network of the Zhongguancun Cluster, the most representative innovative cluster of the high-tech industry in China at present. For this study, Zhongguancun Cluster was the first high-tech cluster to have been created in China, the current Zhongguancun Cluster has played a leading role in the development of the high-tech industry in China. In addition, the Zhongguancun Cluster has at helped elevate China as a key region in terms of research development in relation to the high-tech industry. In particular, companies evaluate the research development network culture of Zhongguancun cluster positively and this increases their tendency to approach the research development network with an open mind. The main contents in research development network are as follows; (1) joint or consigned research development and technology transfer in the case of research development network between companies, (2) joint or consigned research development, human resource support and employment, technical advice and consultant and technology transfer in the case of industrial-educational relationships (3) joint or consigned research development, technical advice and consultant and technology transfer in the case of industrial-research relationships, (4) financial support and participation in joint research development project held by government in the case of industrial and governmental relationships (5) financing for research development, utilization of research human resources, purchase of research development and use of research development equipment for mediators. The main difficulties in creating a research development network are 'lack of mutual trust', 'financial problems of companies' and 'lack of information'. Especially, the main key obstacles for the most important research development network between industry and government in the case of the Zhongguancun Cluster are 'complicated and strict procedures. Therefore, more accurate and detailed understanding of the conditions and the following institutional measures from government are required for research development among companies.

• Korean Journal of Veterinary Pathology
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• v.1 no.2
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• pp.157-160
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• 1997

Two 2 and 7 months-old holstin and one 3 months-old native Korean calf suffering from respiratory illness were submitted to the National Veterinary Research Institute for euthanasia and pathologic examination. At necropsy diffuse lobar pneumonia was present in apical cardiac and diaphragmatic lobes in all calves. Microscopically acute multifocal bronchiolitis and interstitial syncytial cell formation were frequently observed. in addition occlusion of bronchiolar lumen due to cellular proliferation and fibrosis accompanied by interlobular septal emphysema were also present. Immunohistochemically bovine respiratory syncytial virus antigen were positively identified in lung lesions including bronchial and bronchiolar epithelium alveolar macrophages and lymphocytes.

• Nuclear Engineering and Technology
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• v.53 no.9
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• pp.3003-3011
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• 2021

A FAC (flow-accelerated corrosion) test was performed for a straight pipe composed of the SA335 Gr P22 and SA106 Gr B (SA106-SA335-SA106) types of steel with welds as a function of the flow rate in the range of 7-12 m/s at 150 ℃ and with DO < 5 ppb at pH levels ranging from 7 to 9.5 up to a cumulative test time of 7200 h using the FAC demonstration test facility. Afterward, the experimental pipe was examined destructively to investigate opposite effects as well as entrance effects. In addition, the FAC rate obtained using a pipe specimen with a 50 mm inner diameter was compared with the rate obtained from a rotating cylindrical electrode. The effects of the complicated fluid flows at the elbow and orifice of the pipeline were also evaluated using another test section designed to examine the independent effects of the orifice and the elbow depending on the distance and the combined effects on orifice and elbow. The tests were performed under the following conditions: 130-150 ℃, DO < 5 ppb, pH 7 and a flow rate of 3 m/s. The FAC rate was determined using the thickness change obtained from commercial room-temperature ultrasonic testing (UT).

• Proceedings of KOSOMES biannual meeting
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• 2009.06a
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• pp.25-25
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• 2009

• Fisheries and Aquatic Sciences
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• v.12 no.4
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• pp.339-341
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• 2009

Two spiny lobsters of the genus Panulirus, P. stimpsoni Holthuis, 1963 from Jeju Island and P. versicolor (Latreille, 1804) from Busan, are briefly described with colorations. These lobsters are new members of the Korean decapod crustacean fauna. Morphological and distributional accounts of these species are discussed.

• Proceedings of the Korean Society of Dyers and Finishers Conference
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• 2010.03a
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• pp.171-172
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• 2010