The Detection of Bovine Respiratory Syncytial Virus Using Immunohistochemistry and pathologic Findings

면역조직화학염색법을 이용한 소 합포체성 폐렴바이러스의 검출 및 병리학적 소견

  • Yoon, Soon-Seek (National Veterinary Research Institute, Rural Development Administration) ;
  • Hwang, Eui-Kyung (National Veterinary Research Institute, Rural Development Administration) ;
  • Moon, Oun-Kyong (National Veterinary Research Institute, Rural Development Administration) ;
  • Bae, You-Chan (National Veterinary Research Institute, Rural Development Administration) ;
  • Kim, Jae-Hoon (National Veterinary Research Institute, Rural Development Administration) ;
  • Eom, Hyun-Jong (National Veterinary Research Institute, Rural Development Administration) ;
  • Cho, Jae-Jin (National Veterinary Research Institute, Rural Development Administration) ;
  • Jean, Young-Hwa (National Veterinary Research Institute, Rural Development Administration) ;
  • Choi, Sang-Ho (National Veterinary Research Institute, Rural Development Administration)
  • 윤순식 (농촌진흥청 수의과학연구소) ;
  • 황의경 (농촌진흥청 수의과학연구소) ;
  • 문운경 (농촌진흥청 수의과학연구소) ;
  • 배유찬 (농촌진흥청 수의과학연구소) ;
  • 김재훈 (농촌진흥청 수의과학연구소) ;
  • 엄현종 (농촌진흥청 수의과학연구소) ;
  • 조재진 (농촌진흥청 수의과학연구소) ;
  • 진영화 (농촌진흥청 수의과학연구소) ;
  • 최상호 (농촌진흥청 수의과학연구소)
  • Published : 1997.12.01

Abstract

Two 2 and 7 months-old holstin and one 3 months-old native Korean calf suffering from respiratory illness were submitted to the National Veterinary Research Institute for euthanasia and pathologic examination. At necropsy diffuse lobar pneumonia was present in apical cardiac and diaphragmatic lobes in all calves. Microscopically acute multifocal bronchiolitis and interstitial syncytial cell formation were frequently observed. in addition occlusion of bronchiolar lumen due to cellular proliferation and fibrosis accompanied by interlobular septal emphysema were also present. Immunohistochemically bovine respiratory syncytial virus antigen were positively identified in lung lesions including bronchial and bronchiolar epithelium alveolar macrophages and lymphocytes.

Keywords