• 대한치과보철학회지
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• 제24권1호
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• pp.105-116
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• 1986

In order to determine if a relationship exists between the clinical symptoms of TMJ dysfunction and the reproducibility of mandibular movements, twenty one subjects were chosen. The control group consisted of 5 subjects who were determined to be free from signs and symptoms of dysfunction . The sixteen experimental subjects were selected on the basis of their having dysfunctional symptoms. The author obtained two sets of pantographic tracings. Each set consisted of tracings from three both lateral and one protrusive movements. A second set of tracings were recorded immediately on the new recording papers using the same procedure as the first tracing. The tracings were scored by Pantographic reproducibility index (PRI). The obtained results were as follows. 1. Mean PRI scores of groups increased as the degree of dysfunction were increased. 2. For the groups of no or slight dysfunctional symptoms the PRI scores of the second tracing were smaller than the first one, wherea the scores of the second tracing from $D_2,\;D_3$ group were larger than the first tracing. 3. Differences between the mean PRI scores of control group and those of experimental group were statistically significant. 4. The second sets of tracings were more reliable statistically than those of first ones. 5. PRI can be used as a meaningful aid for the evaluation of the diagnostic and therapeutic results of treatment modalities for the TMJ dysfunction. 6. At 3east two sets of tracings should be recorded when the PRI is to be used to detect the incoordinated movements of TMJ dysfunction patient. 7. PRI scores of control group ($D_0$) was 137.7, thus, mandibular movement was reproducible, whereas PRI scores of experimental groups ($D_1,\;D_2,\;D_3$) were 22.5, 27.7, 30.45 respectively, thus were nonreproducible.

• Biomolecules & Therapeutics
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• 제13권1호
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• pp.59-63
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• 2005

A kinetic assay was carried out in order to compare the ability of detection for prekallikrein activator(PKA) in plasma-derived products with that of an endpoint assay and a commercial method. Using these methods, 9 human albumin preparations were assayed and compared to each other. The coefficient of variation between the Kinetic assay and the end point assay was found within 6.6% and this result showed that two methods were highly correlative and the end point assay could act as a replacement of the kinetic assay. Another important goal of this study was to investigate the reproducibility among laboratories on the kinetic assay. A collaborative study was performed to validate the kinetic method with intra and inter assays. The coefficient of variation for the intra assay of each laboratory was less than 4% and that for between individuals in the inter assay was 4.1%. These results revealed that the kinetic assay showed good reproducibility. The contents of PKA in plasma-derived products were also determined by the kinetic assay. As a result, it was found that trace amounts of PKA were present in 32 human immunoglobulin preparations, however the average concentration of PKA in 171 albumin preparations was 5.8 IU/mL.

• 한국환경농학회지
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• 제34권2호
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• pp.111-119
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• 2015

BACKGROUND: Ethychlozate (ECZ) is a plant growth regulator of synthetic auxin for agricultural commodities (ACs). Accurate and sensitive method to determine ECZ in diverse ACs on global official purpose is required to legal residue regulation. As the current official method is confined to the limited type of crops with poor validation, this study was conducted to improve and extend the ECZ method using high-performance liquid chromatography (HPLC) in all the registered crops with method verification. METHODS AND RESULTS: ECZ and its acidic metabolite (ECZA) were both extracted from acidified samples with acetone and briefly purified by dichloromethane partition. ECZ was hydrolyzed to form ECZA and the combined ECZA was finally purified by ion-associated partition including hexane-washing. The instrumental quantitation was performed using HPLC/ FLD under ion-suppression of ECZA with no interference by sample co-extractives. The average recoveries of intra- and inter-day experiment ranged from 82.0 to 105.2% and 81.7 to 102.8%, respectively. The repeatability and reproducibility for intra- and inter-day measurements expressed as a relative standard deviation was less than 8.7% and 7.4%, respectively. CONCLUSION: Established analytical method for ECZ residue in ACs was applicable to the nation-wide pesticide residues monitoring program with the acceptable level of sensitivity, repeatability and reproducibility.

• 대한한의진단학회지
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• 제9권1호
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• pp.112-124
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• 2005

Background: PWV is determined by dividing the distance by the time taken for the pulses traveling between two measuring sites, used as a marker of arterial stiffness and an important indicator for cardiovascular disease. Methods: A PWV measurement system, which offers a non-invasive, simple method of measurement, and simultaneous recording of six signlas(ECG, PCG and four pulse waves from carotid, femoral, radial and dorsalis pedis arteries) was developed. Seventeen healthy subjects with a mean age of 33 years(22 to 52) without any cardiovascular disease were participated for the experiment. Two observers(A and B) performed two consecutive measurements from the same subject in a random order. For the evaluation of stability and accuracy of the PWV measurement system, reproducibility of PWV from between-observer were also evaluated. Results: PWV $values(Mean{\pm}SD)$ measured by A were $7.07{\pm}1.48m/s$, $8.43{\pm}1.14m/s$ , $8.09{\pm}0.98m/s$ for aorta, arm, and leg, respectively. The values obtained from B were $6.76{\pm}1.00m/s$, $7.97{\pm}0.80m/s$, and $7.97{\pm}0.72m/s$ for aorta, arm, and leg, respectively. Between-observer $differences(mean{\pm}SEM)$ from the aorta, arm and leg were $0.14{\pm}0.15m/s$, $0.18{\pm}0.10m/s$ and $0.07{\pm}0.10m/s$. Reproducibility coefficients(2SD) from the aorta, arm, and leg were 0.62m/s, 0.84m/s and 0.86m/s. Correlation coefficients were significantly higher in aortic PWV, 0.93, compared to the coefficients for arm and leg. Coefficient of variance which reflects the reproducibility of the system ranged from $4.4{\sim}5.8%$ in all regional PWV. , Conclusion: Reproducibility of PWV in the study shows that the developed system has reliable and reproducible characteristics. The PWV measurement system used for the study offers comfortable and simple operation and provides accurate analysis and results with high reproducibility. Results of the PWV measurement system could contribute to various clinical applications in the future.

• 대한방사선기술학회지:방사선기술과학
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• 제46권3호
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• pp.219-229
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• 2023

In this study, basic characteristics such as reproducibility, linearity, and directionality of RPL glass dosimeters were evaluated to improve the reliability of dose evaluation through RPL glass dosimeters, and uncertainty elements such as sensitivity by glass element and magazine slot sensitivity were evaluated. Using a mathematical model to calibrate the measured values of the RPL glass dosimeter, the measurement uncertainty was calculated assuming an example. As a result of the characteristic evaluation, the RPL glass dosimeter showed excellent performance with a standard deviation of ±1% (1 SD) for the reproducibility of the reading process, a coefficient of determination for linearity of 0.99997. And the read-out of the RPL glass dosimeter are affected by the circular rotation direction of the glass dosimeter during irradiation, fading according to the period after irradiation, the number of laser pulses of the reader, and response degradation due to repeated reading, it is judged that measurement uncertainty can be reduced by irradiation and reading in consideration of these factors. In addition, it was confirmed that the dose should be determined by calculating the correction factors for the sensitivity of each element and, the sensitivity of each reading magazine slot. It is believed that the reliability of dosimetry using glass dosimeters can be improved by using a mathematical model for correction of glass dosimeter readings and calculating measurement uncertainty.

• Bulletin of the Korean Chemical Society
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• 제31권10호
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• pp.2889-2892
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• 2010

The objective of this study was to validate performance characteristics of the Access 2 (Beckman coulter) system for hCG assays for use as a confirmation test for doping control. The Access 2 assay was linear up to 500 IU/L. The correlation coefficient was higher than 0.999, and the sensitivity of the linearity was 0.82. There were no false positive or false negative cases. LOD was 0.59 IU/L. The method was robust when performed by different people. Repeatability and reproducibility were below 7%. We compared reproducibility and recoveries of Access 2 and Elecsys 2010. Access 2 demonstrated higher reproducibility than Elecsys 2010. Recoveries (accuracy) of Access 2 were between 85 and 105%. Recoveries for Elecsys 2010 were between 91 and 104%.

• 한국기후변화학회지
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• 제9권1호
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• pp.47-58
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• 2018

In this study, we evaluated the uncertainty in the process of selecting GCM and downscaling method for assessing the impact of climate change, and influence of user-centered climate change information on reproducibility of Chungju Dam inflow was analyzed. First, we selected the top 16 GCMs through the evaluation of spatio-temporal reproducibility of 29 raw GCMs using 30-year average of 10-day precipitation without any bias-correction. The climate extreme indices including annual total precipitation and annual maximum 1-day precipitation were selected as the relevant indices to the dam inflow. The Simple Quantile Mapping (SQM) downscaling method was selected through the evaluation of reproducibility of selected indices and spatial correlation among weather stations. SWAT simulation results for the past 30 years period by considering limitations in weather input showed the satisfactory results with monthly model efficiency of 0.92. The error in average dam inflow according to selection of GCMs and downscaling method showed the bests result when 16 GCMs selected raw GCM analysi were used. It was found that selection of downscaling method rather than selection of GCM is more is important in overall uncertainties. The average inflow for the future period increased in all RCP scenarios as time goes on from near-future to far-future periods. Also, it was predicted that the inflow volume will be higher in the RCP 8.5 scenario than in the RCP 4.5 scenario in all future periods. Maximum daily inflow, which is important for flood control, showed a high changing rate more than twice as much as the average inflow amount. It is also important to understand the seasonal fluctuation of the inflow for the dam management purpose. Both average inflow and maximum inflow showed a tendency to increase mainly in July and August during near-future period while average and maximum inflows increased through the whole period of months in both mid-future and far-future periods.

• 순환기질환의공학회:학술대회논문집
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• 순환기질환의공학회 2006년도 제6회 학술대회
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• pp.34-35
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• 2006

• 한국방사선학회논문지
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• 제12권5호
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• pp.651-658
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• 2018

방사선사는 일반촬영 시에 다양한 환자를 만나게 된다. 노령환자, 유아 등 몸이 불편한 환자를 검사하게 된다. 소규모의 병 의원에는 방사선사가 혼자 업무를 보는 경우가 자주 발생한다. 이러한 경우 방사선사의 두 손은 환자의 자세를 유지하는데 사용되어지기 때문에 촬영에 있어서 어려움을 느끼게 된다. 본 연구는 이러한 문제점을 극복하고자 진단용 방사선 발생 발판 스위치를 고안하여 실험하였다. 제작한 발판 스위치를 진단용 엑스선 촬영장치에 장착하여 조사선량 재현성 시험, kVp, mAs, 백분율평균오차와 같은 정량적 평가를 실시하였다. 결과적으로 발판 스위치 사용에 대한 정량적 평가는 조사선량 재현성 시험에서 변동계수가 0.05이하로 측정되었고 kVp 시험에서는 백분율 평균오차가 ${\pm}10%$ 이내로 측정되었다. mAs 시험에서도 백분율 평균오차가 ${\pm}20%$ 이내로 측정되었다. 이는 진단용 방사선 발생장치의 검사기준 범위에 모두 부합하여 사용상 문제점은 제시되지 않았다. 또한 현재 근무 중인 방사선사를 상대로 유용성에 관한 정성적 평가를 실시하였다. 결론적으로 발판스위치의 엑스선 발생효율의 정량적 평가에서는 실험된 검사가 엑스선 발생장치 장비 기준 범위에 부합하였으며 설문을 통한 평가에서도 먼저 병 의원에서 근무하는 방사선사를 상대로 발판 스위치를 사용한 이후 설문을 통해 발판 스위치에 대한 편리성과 활용성에 대해 설문 실시한 결과는 발판스위치 사용은 임상에서 많은 도움을 줄 수 있는 긍정적인 결과로 나타내었다. 그러므로 진단용 엑스선 촬영용 발판 스위치를 사용하면 방사선 기술자 작업의 신속성과 정확성을 효과적으로 향상시킬 수 있으므로 의료 서비스 만족도를 높이는 데 효과적으로 사용할 수 있을 것이다.

• 한국방사선학회논문지
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• 제16권3호
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• pp.211-216
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• 2022

방사선치료에서는 정상조직에 대한 피해를 최소화하면서도 종양조직을 죽이기 위하여 정확한 정도관리 품질보증이 요구된다. 이를 위해서 치료 방사선을 정확하게 계측할 수 있는 선량계가 요구된다. 본 연구에서는 기존 사용되는 검출기 재료로 사용되는 물질보다 저렴하고 제조 공정이 간단하여 기존 물질들을 대체할 수 있는 페로브스카이트 물질에 제조단가를 낮출 수 있고 공정을 간소화 시킬 수 있는 particle in binder(PIB) 방법을 적용하여 민감도가 높은 고효율의 방사선 선량계를 개발하고자 하였다. 고에너지 광자선에 대한 반응특성을 평가함으로써 방사선치료분야에 정도관리 품질보증선량계로 적용 가능한지 적용가능성을 평가하였다. 재현성 평가 결과, 6 MV 에너지에서의 RSD 1.178%로 제시되었고 15 MV에너지에서는 1.141%로 제시되었다. 선형회귀분석에 따른 선형성 평가결과, 6 MV, 15 MV 에너지 각 조건에서 0.9999의 R²값을 제시하였다. 재현성, 선형성 평가결과를 바탕으로 제작된 CsPbBr₃ 선량계의 치료방사선 분야에 정도관리 품질보증 선량계로의 적용가능성이 높은 것으로 나타났다. 본 연구에서 제작된 CsPbBr₃ 선량계는 재현성, 선형성 평가에서 기준이상의 성능을 제시하였으며, 개선을 통하여 치료방사선 정도관리 품질보증 선량계로 활용 가능한 것으로 판단된다.