• Title/Summary/Keyword: Representative Compound

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The Characteristics of Textiles Excavated in Goryeong Jeesandong Tomb No.73 (고령 지산동 제73호분 출토 직물의 특성)

  • Park, Yoon-Mee;Choi, Jae-Hyun
    • Journal of the Korean Society of Costume
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    • v.59 no.6
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    • pp.118-125
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    • 2009
  • Goryeong Jeesandong tombs No.73 from the 5th century located in Gyeongsangbookdo is the most representative remains of the Daegaya. They were excavated and examined by the Daedong Research Center for Cultural Properties. In this study, the textiles in the Goryeong Jeesandong tomb No.73 is identified and their features are examined through scientific analysis. Due to the fact that the remains were not treated for preservation, we were able to observe many samples under the microscope. Within the hemp textiles both hemp and ramie were made using s-twist threads and the thread count distribution is calculated to be 8.0${\sim}$20.0/$cm^2$. Among the silk, the taffeta was categorized into five types. First, there was plain woven silk which the thickness of the warp and the weft is the same and their rate of threadcount was the same. The second type was thin tabby which is spacious between threads. The third kind was woven by warp and weft which had very different thickness. The fourth type used two threads for each warp. The fifth kind used two threads for the warp threads and used thick threads for the weft for a modified plain weave, and it is the first of its kind to be found. Also, there was a compound weave with warp-faced compound weave among silk.

Synthesis and Biological Evaluation of Phenoxy-N-phenylacetamide Derivatives as Novel P-glycoprotein Inhibitors

  • Lee, Kyeong;Roh, Sang-Hee;Xia, Yan;Kang, Keon-Wook
    • Bulletin of the Korean Chemical Society
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    • v.32 no.10
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    • pp.3666-3674
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    • 2011
  • Overexpression of P-glycoprotein (Pgp) is associated with multidrug resistance (MDR) of tumor cells to a number of chemotherapeutic drugs. Pgp inhibitors have been shown to effectively reverse Pgp-mediated MDR. We prepared a series of phenoxy-N-phenylacetamide derivatives and tested for their ability to inhibit Pgp as potential MDR reversing agents, using a Pgp over-expressing MCF-7/ADR cell line. Some of the synthesized compounds exhibited moderate to potent reversal activity. Of note, compound 4o showed a 3.0-fold increased inhibition compared with verapamil, a well-known Pgp inhibitor. In addition, co-treatment of the representative compound 4o and a substrate anticancer agent doxorubicin resulted in a remarkable increase in doxorubicin's antitumor effect and inhibition of DNA synthesis in the MCF-7/ADR cell line. Taken together, these findings suggest that compound 4o could be a useful lead for development of a novel Pgp inhibitor for treatment of MDR.

Determination of vehicle emission factor of NMHC from a tunnel study (터널 측정을 통한 비메탄계 탄화수소의 자동차 배출계수 산정)

  • Na Gwang-Sam;Kim Yong-Pyo;Kim Yeong-Seong;Mun Il
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2000.11a
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    • pp.136-138
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    • 2000
  • The vehicle emissions of primary air pollutants are described by the emission factor (EF), defined as the emitted mass (g) of a compound per distance (km) and vehicle. The EF can be determined by exhaust measurements from single vehicles in dynamometric tests. However, the EF of a large number of vehicles has to be measured to obtain the representative results for actual road traffic emissions. Road traffic emissions can also be determined by exhaust measurements of driving vehicles or in tunnel measurements. (omitted)

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Zygomolgus dentatus n. sp. (Copepoda, Poecilostomatoida, Lichomolgidae) from Korea, with Synonymization of the Genus Lichomolgides with Zygomolgus

  • Kim, Il-Hoi
    • Animal cells and systems
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    • v.10 no.3
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    • pp.169-173
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    • 2006
  • Zygomolgus dentatus n. sp. is described based on specimens from washings of compound ascidians from intertidal shores of Korea. It possesses the long caudal rami which are 5.6 times as long as their width, four scales on the convex side of mandible, and three setal elements and a large process on maxillule. Lichomolgides cuanensis Gotto, the only representative of the genus Lichomolgides, is transferred to the genus Zygomolgus.

The Study on Effect of Exhaust Gas Characteristics according to Aromatic compound Content in Diesel (경유의 방향족 함량 변화가 배출가스에 미치는 영향 연구)

  • Kim, Shin;Min, Kyong-Il;Yim, Eui-Soon;Ha, Jong-Han;Na, Byung-Ki
    • Journal of the Korean Applied Science and Technology
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    • v.31 no.4
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    • pp.549-561
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    • 2014
  • According to reports in EU and USA, Aromatic ingredient in diesel estimated the causative agent of air pollution. Because reduction of total aromatic and Poly-aromatic compound content are decreasing environmentally harmful emissions HC, NOx, PM. It is necessary to investigate correlationship between automotive technology and fuel quality in Korea. This study examines emission effect of two representative domestic vehicles(2.2 L for emission of Euro 4, 5) and five kinds of domestic diesel fuel (total aromatic compound content 26, 28, 30 wt% and poly-aromatic compound content 3, 5 wt%). Finally, Environmental impact assessment was studied between vehicle and diesel fuel.

Electrokinetic Remediation of Organic Mixture Contaminated Soil (복합 유기 오염물로 오염된 세립질 지반의 Electrokinetic 정화 처리에 관한 연구)

  • 김수삼;한상재;김강호
    • Journal of the Korean Geotechnical Society
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    • v.18 no.4
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    • pp.349-356
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    • 2002
  • In this research, phenol was selected as a representative hydrophilic organic compound and phenanthrene as a representative hydrophobic organic contaminant in petroleum. Fine-grained soil which was manufactured artificially in laboratory was contaminated and EK remediation tests were executed. Also, in order to increase removal efficiency, the surfactant that had been used with improvement technique at the pump-and-treat was used by enhanced method. In the test, the phenol which has high solubility is easily removed, but phenanthrene which has low solubility is almost not. Also, it seems to be the delay phenomenon that the phenanthrene is accumulated near the cathode department vicinity at the enhanced technique which applied the surfactant, but the removal efficiency increases as the surfactant concentration increases. By the test which increases with time, the enhanced method with increasing time is more efficient than the method with increasing surfactant.

Knowledge-based Modeling for System Security (시스템 보안을 위한 지식기반 모델링)

  • 서희석;김희원
    • Journal of the Korea Computer Industry Society
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    • v.4 no.4
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    • pp.491-500
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    • 2003
  • The need for network security is being increasing due to the development of information communication and internet technology, In this paper, firewall models, operating system models and other network component models are constructed. Each model Is defined by basic or compound model using MODSIM III. In this simulation environment with representative attacks, the following attacks are generated, SYN flooding and Smurf attack as an attack type of denial of service. The simulation is performed with the models that exploited various security policies against these attacks. In addition, the results of the simulation show that the analysis of security performance according to various security policies, and the analysis of correlation between availability and confidentiality according to security empowerment.

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Effect of Sodium Taurodeoxycholate on Biliary Excretion of Amaranth as an Anionic Model Drug in Rats (음이온 모델 화합물 아마란스의 담즙배설에 미치는 타우로데옥시콜레이트의 영향)

  • Shim, Chang-Koo;Chung, Suk-Jae
    • Journal of Pharmaceutical Investigation
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    • v.16 no.3
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    • pp.110-117
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    • 1986
  • Plasma disappearance of amaranth (AM), a model compound of organic anionic drugs, was retarded by intravenous infusion of taurodeoxycholate (TDC), a representative bile acid, in the rat. Biliary excretion accounted for 30-60% of the systemic excretion of AM. AM seemed to be metabolised in the hepatocyte to form a compound that is excreted more rapidly into the bile than AM itself, considering apparent biliary clearance, $CL_{bil}$, is much larger than systemic clearance, $CL_s$. Decrease in $CL_{bil}$ by TDC infusion might be due to elevated plasma level rather than decreased biliary excretion of AM. Decreased distribution or urinary excretion of AM by TDC was supposed to be one of the probable reasons of elevated plasma level. Competitive inhibition between AM and TDC on tissue distribution and urinary excretion might explain the mechanism. The effect of TDC on the $CL_{bil}$ of methylene blue, a cationic dye, was quite different from that of AM, as reported previously by us. More intensive study would be necessary to elucidate the difference of biliary excretion between organic anions and cations.

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High functional biodegradable card through annealing (어닐링을 통한 고기능성 생분해성 카드)

  • Sim, Jae-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.2
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    • pp.280-286
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    • 2020
  • Cards made from PVC and PET materials do not oxidize or decompose readily, so they are generally incinerated or landfilled after use and cause pollution problems, such as environmental hormones and combustion gases during incineration. In addition, there is a problem of environmental pollution because they are discarded as semi-permanent refuse without being decomposed at landfill. This study attempted to solve this problem using polylactic acid (PLA), which is a representative biodegradable material as a substitute material that can solve the issues with these cards. On the other hand, when the thin card core sheet is made from only PLA material, the physical properties of the material are insufficient, such as the low temperature impact strength, high temperature stability, and poor bending properties, so its use is limited. To solve this problem, the compositional ratio of PLA was reviewed, and the optimal biodegradable compound composition was determined through an examination of the compositions, such as crystallization nucleating agents, additives, and nano compound technology. The high functionalization as a biodegradable card was verified through a laminating process using annealing technology.

A Study on Flow Characteristics according to Meandering Low Flow Channel Shape in the Compound Cross Section Typed Straight Channel (복단면인 직선수로 내 사행 저수로의 형태에 따른 흐름특성 연구)

  • Kim, Seonghwan;Choi, Gyewoon
    • Journal of Wetlands Research
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    • v.19 no.4
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    • pp.484-490
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    • 2017
  • In order to examine flow characteristics according to the shape of the meandering low flow channel in the compound cross section typed straight channel, we assumed the representative channel type in Korea and confirmed the validity of the 3D numerical simulation by carrying out the hydraulic model. Based on this study, numerical simulations were also conducted on other types of river channel. As a result of the numerical model test (using the velocity value measured by the water depth observation from the hydraulic model test), it was confirmed that the numerical simulation results are in good agreement with the numerical simulation results. As a result of analyzing the flow field according to the changes in the shape of the low flow channel, it was confirmed that the secondary flow examined in the previous studies occurred. Also, it was confirmed that the maximum flow velocity point moves according to the expansion cross sectional area of flow in high flow plain. Ultimately, it is thought that it is necessary to understand the position of the water impingement (which is an important factor in river design) and the extent of the impact because the change of the channel width affects the flow.