• Title/Summary/Keyword: Renal pathology

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MRI Findings of Renal Myxoma: A Case Report and Literature Review (신장 점액종의 MRI 소견: 증례 보고와 문헌고찰)

  • Sung Hyun Yu;Young Sup Shim;So Hyun Park;Seung Joon Choi;Dong Hae Chung;Sang Jin Yoon
    • Journal of the Korean Society of Radiology
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    • v.83 no.1
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    • pp.162-167
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    • 2022
  • Renal myxomas are very rare benign tumors. To date, a few cases have been reported in English literature, mostly in pathology and urology journals. Thus, there are few reports on the radiological findings associated with renal myxomas. We report on the imaging findings in a case of renal myxoma in a 62-year-old male. MRI demonstrated a well-defined mass in the left renal sinus, with intermediate high signal intensity on T2-weighted images and low signal intensity on T1-weighted images. The tumor showed gradual enhancement on contrast-enhanced T1-weighted images.

Human Renal Dipeptidase from Kidneys of Renal Stone Patients: Partial Characterization

  • Park, Haeng-Soon;Kim, Doh-Ha;Kwark, Hyung S.Ellen;Park, Sung-Kwang;Kang, Sung-Kyew
    • Archives of Pharmacal Research
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    • v.17 no.1
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    • pp.21-25
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    • 1994
  • Physico-chemical characterization of human renal dipeptidase was carried out. It was a glycoprotein with a subunit MW of approximately 47,700 dalton. The pH optimum was at 8 and its stable conformation was retained between pH 5 and 12. The kinetic parameters determined with imipenem, a noval ${\beta}-lactam$ antibiotic, were Vmax, $5.21\;\mu{mol/min/mg}$; km, 4.35 mM ; and Ki with cilastatin, $0.25\;\mu{M}$ Cilastatin demonstrated reversible competitive inhibition.

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Urinary Change of Kallikrein in Adenine-Induced Renal Failure Rat (Adenine 유발 신부전 흰쥐에서의 뇨중 Kallikrein의 변화)

  • Lee, Tae-Woong;Seo, Suk-Soo;Lee, Kyung-Hee;Young, Han-Suk;Chung, Joon-Ki;Choi, Jae-Sue
    • YAKHAK HOEJI
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    • v.35 no.6
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    • pp.504-508
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    • 1991
  • In order to investigate whether the function of distal nephron is disturbed in adenine-induced renal failure rats, we measured the urinary kallikrein level in adenine-ingesting rats fed on 0.75% adenine diet for 1 to 10 days. Administration of 0.75% adenine to rats significantly increased blood urea nitrogen level and urine volume, while the level of kallikrein along with the urinary excretions of urea and inorganic phosphate were significantly decreased. From these results, it is suggested that adenine-induced renal failure is caused by early deterioration of distal nephron as well as proximal nephron.

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Ceramide Induces Cell Death through an ERK-dependent Mitochondrial Apoptotic Pathway in Renal Epithelial Cells

  • Jung, Soon-Hee
    • Korean Journal of Clinical Laboratory Science
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    • v.42 no.1
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    • pp.46-54
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    • 2010
  • Ceramide induces cell death in a variety of cell types however, the underlying molecular mechanisms related to renal epithelial cells remain unclear. The present study was undertaken to determine the role of extracellular signal-regulated protein kinase (ERK) in ceramide-induced cell death in renal epithelial cells. An established renal proximal tubular cell line of opossum kidney (OK) cells was used for this research. Ceramide induced apoptotic cell death in these cells. Western blot analysis showed that ceramide induced activation of ERK. The ERK activation and cell death induced by ceramide were prevented by the ERK inhibitor PD98059. Ceramide caused cytochrome C release from mitochondria into the cytosol as well as activation of caspase-3. Both effects were prevented by PD98059. The ceramide-induced cell death was also prevented by a caspase inhibitor. These results suggest that ceramide induces cell death through an ERK-dependent mitochondrial apoptotic pathway in OK cells.

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Regulation of Calcium Concentration in Primary and Secondary Hyperparathyroidism

  • Kim, Yong-baek
    • Proceedings of the Korean Society of Veterinary Pathology Conference
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    • 2003.10a
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    • pp.35-38
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    • 2003
  • The parathyroid gland is probably the simplest endocrine organ in the body. The only cells of clinical significance are the parathyroid or chief cells. The primary signal that these cells listen to is calcium. Primary hyperparathyroidism is due to a parathyroid adenoma. The most common cause of hypercalcemia in veterinary medicine is hypercalcemia of malignancy associated with variety of neoplasms. Secondary hyperparathyroidism is due to a disease process, most commonly associated with renal and nutritional hyperparathyroidism. Primary and secondary hyperparathyroidism are markedly different in their clinical, laboratory, and pathogenic mechanism.

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A Case of Multilocular Cystic Nephroma in Childhood (소아 다방성 낭포성 신종 1례)

  • Choi Min Sook;Lee Young-Mock;Kim Ji Hong;Kim Pyung Kil;Jeong Hyeon Joo;Kim Myung Joon
    • Childhood Kidney Diseases
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    • v.5 no.2
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    • pp.225-230
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    • 2001
  • Multilocular cystic nephroma is a rare disease, noninherited benign renal neoplasm occurring in both children and adults. It is necessary to make a differential diagnosis from all renal diseases with a cystic component, such as Wilms tumor, harmatoma or polycystic dysplastic kidney in childhood. There are about only 200 case reports in the world since Walter Edmunds had described it first. We report a case of multilocular cystic nephroma presented with painless abdominal mass, treated with nephrectomy and confirmed with pathology. (J. Korean Soc Pediatr Nephrol 2001 ;5 : 219-24)

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Renal Candidiasis in a Masked Palm civet (Paguma larvata) (백비심에서 자연 발생한 신장의 칸디다증)

  • Kim, Dae-Yong;Yoo, Han-Sang;Bae, Ji-Seon;Choi, Jae-Hoon;Park, Ju-Yeon;Kim, Young-Kun;Jung, Young-Mok
    • Korean Journal of Veterinary Pathology
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    • v.3 no.2
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    • pp.95-97
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    • 1999
  • A case of renal candidiasis is reported in a 4-year-old male Masked Palm civet (Paguma larvata) On necropsy, the kidneys were bilaterally swollen, pale and had numerous 1 to 3 mm diameter white foci throughout the parenchyma on cut section. The urinary bladder was filled with opaque and milky exudate. Histologically, severe infiltration of neutrophils and macrophages and necrosis were noted in the interstitial areas of both cortex and medulla and in the lumens of renal tubules and collecting duct often resulting in cystic dilation of the tubules. PAS-positive fungal yeasts or pseudohyphae were often associated with the lesion. Candida albicans was isolated from the kidney and urinary bladder.

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A Four-year Follow-up Case of Oligomeganephronia Detected Early by School Screening Urinalysis (학교선별뇨검사를 통하여 조기에 발견된 Oligomeganephronia의 4년 추적 관찰 1례)

  • Ham Ju-Yeon;Koo Nam-Hyang;Lim Hyun-Yi;Kim Kee-Hyuck;Pai Ki-Soo
    • Childhood Kidney Diseases
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    • v.7 no.2
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    • pp.223-228
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    • 2003
  • Oligmeganephronia is congenital hypoplasia of kidney with renal pathology showing very small number of nephrons with compensatory hypertrophy of the remaining glomeruli. A 7-year-old girl was referred to our nephrology clinic due to hematuria detected on school screening urinalysis and diagnosed as chronic renal failure and oligomeganephronia on renal biopsy. We are reporting the clinical and histomorphometric changes for the four years follow-up with review of literatures.

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