• 제목/요약/키워드: Removal mechanism

검색결과 643건 처리시간 0.026초

In-process Topographical Evaluation of CBN wheel surface

  • Lee, Joosang;Kim, Heenam;Minsung Hong
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 한국전기전자재료학회 1998년도 춘계학술대회 논문집
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    • pp.507-513
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    • 1998
  • In surface grinding, the conditions of the grinding wheel has much more significant effect on the machined workpiece as compared to other metal removal processes. The contact between the grinding wheel and the workpiece introduce heat and resistance, which restrict the self-dressing of the grits and result in burrs cracks on the workpiece. Therefore, before or during the grinding operation, it is necessary to self-dressing the grinding wheel for more accurate performance. In general, however, the choice of the dressing time has made by the operator's own decision or the condition of the workpiece. In this paper, a new method for finding the optimal dressing time of the grinding wheel is proposed. In order to develop a more sophisticated methodology, a non-contacting in-process optical measurement method using a laser beam has been introduced to find the glazing, loading, and spilling of the grinding wheel Simultaneously, a three-dimensional computer simulation of the grinding operation has been attempted based on the contact mechanism between the grinding wheel and the workpiece. The grains of the grinding wheel are simulated and the optimal dressing time is determined based on the amount of grain wear and work surface roughness.

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Therapeutic implication of autophagy in neurodegenerative diseases

  • Rahman, Md. Ataur;Rhim, Hyewhon
    • BMB Reports
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    • 제50권7호
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    • pp.345-354
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    • 2017
  • Autophagy, a catabolic process necessary for the maintenance of intracellular homeostasis, has recently been the focus of numerous human diseases and conditions, such as aging, cancer, development, immunity, longevity, and neurodegeneration. However, the continued presence of autophagy is essential for cell survival and dysfunctional autophagy is thought to speed up the progression of neurodegeneration. The actual molecular mechanism behind the progression of dysfunctional autophagy is not yet fully understood. Emerging evidence suggests that basal autophagy is necessary for the removal of misfolded, aggregated proteins and damaged cellular organelles through lysosomal mediated degradation. Physiologically, neurodegenerative disorders are related to the accumulation of amyloid ${\beta}$ peptide and ${\alpha}-synuclein$ protein aggregation, as seen in patients with Alzheimer's disease and Parkinson's disease, respectively. Even though autophagy could impact several facets of human biology and disease, it generally functions as a clearance for toxic proteins in the brain, which contributes novel insight into the pathophysiological understanding of neurodegenerative disorders. In particular, several studies demonstrate that natural compounds or small molecule autophagy enhancer stimuli are essential in the clearance of amyloid ${\beta}$ and ${\alpha}-synuclein$ deposits. Therefore, this review briefly deliberates on the recent implications of autophagy in neurodegenerative disorder control, and emphasizes the opportunities and potential therapeutic application of applied autophagy.

Impact of Multi-dimensional Core Thermal-hydraulics on Inherent Safety of Sodium-Cooled Fast Reactor (다차원 노심열수력 현상이 소듐고속로 고유안전성에 미치는 영향)

  • Kwon, Young-Min;Jeong, Hae-Yong;Ha, Kwi-Seok
    • Proceedings of the KSME Conference
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    • 대한기계학회 2008년도 추계학술대회B
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    • pp.3175-3180
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    • 2008
  • A metal-fueled pool-type liquid metal fast reactor (LMFR) provides large margins to sodium boiling and fuel damage under accident conditions. The favorable passive safety results are obtained by both a reactivity feedback mechanism in the core and a passive decay heat removal system. Among the various reactivity feedbacks, the ones by a thermal expansion of a radial dimension of the core and by the control rod drivelines are strongly dependent on the flow conditions in the core and the hot pool, respectively. The effects of multidimensional thermal hydraulic characteristics on these reactivity feedbacks are investigated by the system-wide safety analysis code SSC-K with advanced thermal hydraulics models. Particularly a detailed three dimensional thermal hydraulics reactor core model is integrated into SSC-K for use in a whole system analysis of the passive safety aspects of LMR designs. The model provides fuel and cladding temperatures for every fuel pin in a reactor and coolant temperatures for every coolant sub-channel in the reactor.

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Bleomycin Sclerotherapy of Lymphatic Maformation in Head and Neck (Bleomycin을 이용한 선천성 림프관기형의 경화요법)

  • 성명훈;장선오;정종우;김진영
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 대한기관식도과학회 1993년도 제27차 학술대회 초록집
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    • pp.108-108
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    • 1993
  • Cystic hygroma is a congenital anomaly of the lymphatic system for which the exact pathogenetic mechanism remains to be elucidated. It is filled with lymphatic fluid and commonly present in the cervical area in either single isolated or multiple form. It is usually innocuous without any pain but may be life-threatening when it is large enough to compromise the airway or interfere with swallowing. Since spontaneous regressions rarely occur, it requires surgical removal. However, this may be rendered difficult in multiple forms and in those with extensive infiltration into the surrounding tissue. This is a presentation of 10 pediatric patients with cystic hygroma who have been successfully treated by sclerotherapy using bleomycin at the authors' department.

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Study on the Recycling of Nuclear Graphite after Micro-Oxidation

  • Liu, Juan;Wang, Chen;Dong, Limin;Liang, Tongxiang
    • Nuclear Engineering and Technology
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    • 제48권1호
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    • pp.182-188
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    • 2016
  • In this paper, a feasible strategy for the recycling of nuclear graphite is reported, based on the formation mechanism and the removal of carbon-14 by micro-oxidation. We investigated whether ground micro-oxidation graphite could be used as a filler to make new recycled graphite and which graphite/pitch coke ratio will give the recycled graphite outstanding properties (e.g., apparent density, flexural strength, compressive strength, and tensile strength). According to the existing properties of nuclear graphite, the ratio of graphite to pitch coke should not exceed 3. The recycled reactor graphite has been proven superior in density, strength, and thermal conductivity. The micro-oxidation process enhances the strength of the recycled graphite because there are more pores and unsmooth surfaces on the oxidized graphite particles, which is beneficial for the access of the pitch binder and leads to efficient joint adhesion among the graphite particles.

Mechanism of TCE Removal with Foundry Sands and Design of Permeable ]Reactive Barriers (주물사의 TCE 제거 메커니즘과 반응벽체에의 적용가능성)

  • ;Benson, Craig H
    • Journal of the Korean Geotechnical Society
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    • 제18권5호
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    • pp.143-157
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    • 2002
  • Batch and column tests were conducted with common groundwater contaminants (i.e., trichloroethylene) to determine transport parameters and reactivity of the foundry sands. The reactivities of foundry sands for common groundwater contaminants are comparable to or slightly higher than those for Peerless iron a common medium used in permeable reactive barriers. In addition, the TOC and clay in foundry sands can significantly retard the movement of target contaminants, which may result in lower effluent concentrations of contaminants due to biodegradation. In general, permeable reactive barriers with the thickness of 1m can be constructed with many foundry sands to treat typical groundwater comtaminants provided the zero-valent iron content in the foundry sand is higher than 1%.

Image Observation of NO Particles Using ICCD Camera (ICCD Camera를 이용한 NO입자의 Image관측)

  • 전용우;하장호;박원주;이광식
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • 제15권1호
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    • pp.98-103
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    • 2001
  • In this parer, the removal rate of NO in a reactor is rreasured first using nonthermal plasma generated from a wire-cylinder type reactor, then the discharge image and horizontal signal strength and vertical signal strength of NO particles is observed using ICCD(Intensified Charged Coupled Device) carrera It was fOlmd that NO rerroval rate was iflLTeased with NO concentration c1ecreasing, and that honzontal signal strength and vertical signal strength were also increased with NO concentration decreasing. Especially, this research is a1!Tffl at clarifying the discharge mechanism of NO particles by observing the images of AC discharge wnen the nonthermal plasma generated by an discharge was used.

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A Study on CMP Mechanism of $Bi_{3.25}La_{0.75}Ti_{3}O_{12}$ (BLT) Thin Films ($Bi_{3.25}La_{0.75}Ti_{3}O_{12}$ (BLT) 박막의 CMP 메커니즘 연구)

  • Shin, Sang-Hun;Ko, Pil-Ju;Kim, Nam-Hoon;Lee, Woo-Sun
    • Proceedings of the KIEE Conference
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    • 대한전기학회 2006년도 제37회 하계학술대회 논문집 C
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    • pp.1450-1451
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    • 2006
  • In this paper, we first applied the chemical mechanical polishing (CMP) process to the planarization of ferroelectric film in order to obtain a good planarity of electrode/ferroelectric film interface. $Bi_{3.25}La_{0.75}Ti_{3}O_{12}$ (BLT) ferroelectric fan was fabricated by the sol-gel method. Removal rate and non-uniformity (WIWNU%) were examined by change of silica slurries pH(10.3, 11.3, 12.3). Surface roughness of BLT thin films before and after CMP process was inquired into by atomic force microscopy (AFM). Effects of silica slurries pH(10.3, 11.3, 12.3) were investigated on the CMP performance of BLT film by the surface analysis of X-ray photoelectron spectroscopy(XPS).

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CHROMIUM LEACHABILITY FROM STABILIZED/SOLIDIFIED SOILS UNDER MODIFIED SEMI-DYNEMIC LEACHING CONDITIONS

  • Moon, Deok-Hyun
    • Environmental Engineering Research
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    • 제10권6호
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    • pp.294-305
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    • 2005
  • The effectiveness of fly ash-, quicklime-, and quicklime-fly ash-based stabilization/solidification(S/S) in chromium(Cr) contaminated soils was investigated using modified semi-dynamic leaching tests. Artificial soil samples composed of kaolinite or montmorillonite contaminated with chromium nitrate(4000 mg $Cr^{3+}\;kg^{-1}$ of solid) were prepared and then subjected to S/S treatment using quicklime, fly ash, or quick lime-fly ash. The effectiveness of the treatment was evaluated by assessing the cumulative fraction of leached $Cr^{3+}$ as well as, by computing the effective diffusivity ($D_e$) and the leachability index (LX) of the treated samples. The reduction in $Cr^{3+}$ release for the untreated samples was more pronounced in the presence of montmorillonite, which was attributed to sorption. Treatment with quicklime, fly ash, or quick lime-fly ash was significantly effective in reducing $Cr^{3+}$ release most probably due to the formation of pozzolanic reaction products and $Cr(OH)_3$ precipitation. The most effective treatment was observed in montmorillonite-sand soil samples treated with quicklime-fly ash (99.8% removal). The mean $D_e$ decreased significantly and the mean LX was greater than 9 for all treated samples, indicating that the treated soils were acceptable for "controlled utilization". The mechanism controlling $Cr^{3+}$ leaching from all treated samples during the first 5 days appeared to be diffusion.

Synthesis and Application of Metal Doped Silica Particles for Adsorptive Desulphurization of Fuels

  • Jabeen, Bushra;Rafique, Uzaira
    • Environmental Engineering Research
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    • 제19권3호
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    • pp.205-214
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    • 2014
  • Petroleum a vital commodity affecting every aspect of 21st century. Toxicity and adverse effects of sulphur as catalyst in petroleum products is of great concern required development of techniques for desulphurization in compliance with the International standards. Installation of desulphurizing units costs over $200 million per unit placing economic burden on developing countries like Pakistan. Present study analysis of commercial fuels (station petrol and jet fuel JP8) on gas chromatography-mass spectrometry (GC-MS) identified sulphur concentration of 19.94 mg/L and 21.75 mg/L, respectively. This scenario urged the researcher to attempt synthesis of material that is likely to offer good adsorption capacity for sulphur. Following protocol of sol-gel method, transition metals (Ni, Cu, Zn) solution is gelated with tetraethoxysilane (TEOS; silica precursor) using glycerol. Fourier transform infrared spectroscopy (FTIR) spectra revealed bonding of Zn-O, Cu-O, and Ni-O by stretching vibrations at $468cm^{-1}$, $617cm^{-1}$, and $468cm^{-1}$, respectively. Thiophene and Benzothiophene mixed in n-heptane and benzene (4:1) for preparation of Model Fuels I and II, respectively. Each of silica based metal was applied as adsorbent in batch mode to assess the removal efficiency. Results demonstrated optimal desulphurization of more than 90% following efficacy order as Si-Ni > Si-Zn > Si-Cu based adsorbents. Proposed multilayered (Freundlich) adsorption mechanism follows ${\pi}$-complexation with pseudo secnd order kinetics.