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Effects of exercise on sleep EEG following caffeine administration (카페인 투여 후 운동이 수면에 미치는 효과)

  • 윤진환;이희혁
    • Journal of Life Science
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    • v.12 no.4
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    • pp.375-382
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    • 2002
  • The purpose of this experiment was to examine influence of acute exercise on nocturnal sleep which had been disrupted by caffeine(400mg$\times$3) thought the daytime. Six healthy young males aged 21.0$\times$0.2 yr with a history of low caffeine use. Subjects completed three conditions in a within-subject. At three conditions Sleep EEG were investigated: (1) nocturnal following quiet rest, (2) nocturnal sleep following the consumption of 1200mg of caffeine (3) nocturnal sleep following cycling at 60 min of 60% V $O_{2peak}$ with 1200mg of caffeine consumption. Sleep data were calculated for REM sleep, REM latency, sleep onset latency, sleep efficiency, sleep stages, SWS. Those data were analyzed using repeated-measures ANOVA of change scores. A main effect to, drug(caffeine) indicated that caffeine elicited sleep disturbance that is, TST and sleep onset latency increase and sleep efficiency and stage 4 decrease. The effects of exercise on sleep following caffeine intake generally improve sleep that is, stage 2, 3 and SWS increase and sleep onset latency decrease. A condition effect for sleep indicated sleep improvement after exercise Therefore The data supported a restorative theory of slow-wave sleep and suggest that acute exercise may be useful in promoting sleep and reducing sleep disturbance elevated by a high dose of caffeine.

Sleep Disturbances in Patients with Parkinson's Disease according to Disease Severity (파킨슨병의 중증도에 따른 수면 장애)

  • Lee, Su-Yun;Cheon, Sang-Myung;Kim, Jae Woo
    • Annals of Clinical Neurophysiology
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    • v.17 no.1
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    • pp.17-23
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    • 2015
  • Background: Sleep-related disturbances and sleep disorders are common in Parkinson's disease (PD) and have a great impact on daily life of PD patients. This study was done to find the sleep characteristics and sleep disturbing factors in PD patients according to disease severity through clinical interview and polysomnographic (PSG) study. Methods: Fifty patients with PD (22 males, age $60.6{\pm}6.4$, Hoehn and Yahr (HY) stage $2.7{\pm}1.0$) were recruited and thoroughly interviewed about their sleep. PSG was performed on the patients taking routine antiparkinsonian medications. Patients were grouped into mild and moderate/severe group according to HY stage, and the results were compared between each group. Results: Ninety-four percent of total patients had one or more sleep-related disturbances based on the interview or PSG. On interview, the moderate/severe group complained more insomnia and REM sleep behavior disorder (RBD) than mild group. In PSG findings, the moderate/severe group showed lower sleep efficiency, longer sleep latency, REM sleep latency, waking time after sleep onset, and higher prevalence of RBD. Conclusions: In this study, most patients with PD had sleep disturbances. Clinical interview and PSG findings revealed deterioration of sleep quality along the disease severity. Our results suggest that sleep disturbances in PD patients are prevalent and warrant clinical attention, especially to the patients with advanced disease.

A Study on the Transformal Usage of Visual Information in Architectural Diagrams - Focusing on the Projects by Rem Koolhaas and MVRDV - (건축다이어그램에 나타난 시각정보의 변음방식에 관한 연구 - 렘 쿨하스와 MVRDV의 프로젝트를 중심으로 -)

  • Park, Young-Ho
    • Korean Institute of Interior Design Journal
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    • v.17 no.6
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    • pp.71-81
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    • 2008
  • The purposes of this research are to correctly understand the relationship between a visual communication structure and a semantic communication structure when integrating and changing various architectural visual information. This study will classify various diagrams, which have been actively applied to the works of Rem Koolhaas and MVRDV when designing architecture, and based on the classification, it will analyze how the expression viewpoints inherent in the diagrams are changed and applied to processing and changing architectural visual information. The transformal usage of the visual information of architectural diagrams is classified into an analysis-centered processing method and a concept-centered processing method, and the characteristics of their usage are analyzed. The former shows an observer-centered expression viewpoint which effectively delivers an architect's analyzed architectural information or intent to a customer or an observer. It also allows an easy perception of the analyzed data, and uses qualitative expression viewpoints. The method combines systematic expression viewpoints, which value a relationship with visual information, and various architectural visual information; uses the combined expression viewpoints as one diagram for delivering various information simultaneously and for changing visual information. The latter shows author-centered subjective expression viewpoints, which are different from reproduction-centered fixed expression viewpoints. This method uses arbitrary expression viewpoints that overly extort, change or manipulate visual information. It shows simultaneous expression viewpoints that integrate various architectural visual information via omniscient expression viewpoints, such as reversing or projecting the points of viewing subjects, which human beings cannot perceive.

A Study on Expressive Aspects of Subversive Mimesis Found in Architectural Design - With a Focus on the Concepts of Appropriation and Détournment - (건축디자인에 나타난 전복적 미메시스의 표현특성 연구 - 전유, 전용을 중심으로 -)

  • Park, Young-Tae
    • Korean Institute of Interior Design Journal
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    • v.22 no.2
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    • pp.68-80
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    • 2013
  • This study is about expressive aspects of subversive mimesis found in architectural design under 2nd Modernity. Architectural works under 2nd Modernity are described based on pseudo-scientific positivism and philosophical ontology of Deleuze. However, subversiveness found in works of arts by architects such as Rem Koolhaas present a few complexities to relay on such a description. This is about 'subversiveness' which absorbs the positive and negative factors of modernity which has been multi-layered as 'cultural capital'. This study aims to identify meta-phenomenon as well as the specific correlations between expression and purposes of any work of art that is presented in the form of subversiveness. To achieve this aim, this study approached with the concepts of appropriation and detournment based on Adorno's subversive mimesis concept. Meta-phenomena of architectural design methods occur from relations of three, which are social reality, artist, and work of art. This was connected to productivity of mimesis practice of self-reference and self-examination, which was then, summed up from the perspectives of appropriation in pure arts and d$\acute{e}$tournment of situationalists. Based on this work, subversive expressive characteristics of architecture under 2nd Modernity were framed from the perspectives of the absorption of cultural capital, reflection and negation, autonomy, instrumentality, and meta properties. In this way, this study found that Adorno's subversiveness should be effective for creative and methodological systemization in terms of interpretation of cognition, practice, and effect after materialization.

EEG Characteristic Analysis of Sleep Spindle and K-Complex in Obstructive Sleep Apnea

  • Kim, Min Soo;Jeong, Jong Hyeog;Cho, Yong Won;Cho, Young Chang
    • Journal of Korea Society of Industrial Information Systems
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    • v.22 no.1
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    • pp.41-51
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    • 2017
  • This Paper Describes a Method for the Evaluation of Sleep Apnea, Namely, the Peak Signal-to-noise ratio (PSNR) of Wavelet Transformed Electroencephalography (EEG) Data. The Purpose of this Study was to Investigate EEG Properties with Regard to Differences between Sleep Spindles and K-complexes and to Characterize Obstructive Sleep Apnea According to Sleep Stage. We Examined Non-REM and REM Sleep in 20 Patients with OSA and Established a New Approach for Detecting Sleep Apnea Base on EEG Frequency Changes According to Sleep Stage During Sleep Apnea Events. For Frequency Bands Corresponding to A3 Decomposition with a Sampling Applied to the KC and the Sleep Spindle Signal. In this Paper, the KC and Sleep Spindle are Ccalculated using MSE and PSNR for 4 Types of Mother Wavelets. Wavelet Transform Coefficients Were Obtained Around Sleep Spindles in Order to Identify the Frequency Information that Changed During Obstructive Sleep Apnea. We also Investigated Whether Quantification Analysis of EEG During Sleep Apnea is Valuable for Analyzing Sleep Spindles and The K-complexes in Patients. First, Decomposition of the EEG Signal from Feature Data was Carried out using 4 Different Types of Wavelets, Namely, Daubechies 3, Symlet 4, Biorthogonal 2.8, and Coiflet 3. We Compared the PSNR Accuracy for Each Wavelet Function and Found that Mother Wavelets Daubechies 3 and Biorthogonal 2.8 Surpassed the other Wavelet Functions in Performance. We have Attempted to Improve the Computing Efficiency as it Selects the most Suitable Wavelet Function that can be used for Sleep Spindle, K-complex Signal Processing Efficiently and Accurate Decision with Lesser Computational Time.

Noncontact Sleep Efficiency and Stage Estimation for Sleep Apnea Patients Using an Ultra-Wideband Radar (UWB 레이더를 사용한 수면무호흡환자에 대한 비접촉방식 수면효율 및 수면 단계 추정)

  • Park, Sang-Bae;Kim, Jung-Ha
    • Journal of the Korean Society of Industry Convergence
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    • v.23 no.3
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    • pp.433-444
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    • 2020
  • This study proposes a method to improve the sleep stage and efficiency estimation of sleep apnea patients using a UWB (Ultra-Wideband) radar. Motion and respiration extracted from the radar signal were used. Respiratory signal disturbances by motion artifacts and irregular respiration patterns of sleep apnea patients are compensated for in the preprocessing stage. Preprocessing calculates the standard deviation of the respiration signal for a shift window of 15 seconds to estimate thresholds for compensation and applies it to the breathing signal. The method for estimating the sleep stage is based on the difference in amplitude of two kinds of smoothed respirations signals. In smoothing, the window size is set to 10 seconds and 34 seconds, respectively. The estimated feature was processed by the k-nearest neighbor classifier and the feature filtering model to discriminate between the sleep periods of the rapid eye movement (REM) and non-rapid eye movement (NREM). The feature filtering model reflects the characteristics of the REM sleep that occur continuously and the characteristics that mainly occur in the latter part of this stage. The sleep efficiency is estimated by using the sleep onset time and motion events. Sleep onset time uses estimated features from the gradient changes of the breathing signal. A motion event was applied based on the estimated energy change in the UWB signal. Sleep efficiency and sleep stage accuracy were assessed with polysomnography. The average sleep efficiency and sleep stage accuracy were estimated respectively to be about 96.3% and 88.8% in 18 sleep apnea subjects.

A Study of Radon Concentration in First Floor and Basement and Prediction of Annual Exposure Rate in Korea (국내 실내 라돈농도와 연간 피폭선량 예측에 관한 연구)

  • Lee, Jong-Dae;Kim, Yoon-Shin;Son, Bu-Soon;Kim, Dae-Seon
    • Journal of Environmental Science International
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    • v.15 no.4
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    • pp.311-317
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    • 2006
  • The purpose of this study was to investigate Rn concentration and annual radiation exposure level in the basement and first floor. The Rn Cup monitors were placed in different environments such as shopping stage, office building, Apartment, Hospital, house in Seoul from Match 1996 to April 1997 and CR-39 films were collected every two months. The mean radon concentration in the basement of house($88.6\;Bq/m^3$) showed the highest level among the areas, while radon concentration on the first floor of house($50.5\;Bq/m^3$) showed the higher than other areas. The annual radiation exposure dose that person on the floor / in the basement of differential place in the seoul can be exposed during living was estimated from 24.11 to 87.64 mRem/yr. This radiation dose is significantly lower than 130mRem maximum radiation dosage from the radon nuclide prescribed by the ICRP, with respect to the overall average exposure of the working adult. this study indicated that possible radon sources on the first floor / in the basement areas are radon intrusion from soil gas, construction materials, or ground water leaking. Further study is needed to quantitatively assess major contributions of radon-222 and health effect to radon exposure.

Prediction of Sleep Stages and Estimation of Sleep Cycle Using Accelerometer Sensor Data (가속도 센서 데이터 기반 수면단계 예측 및 수면주기의 추정)

  • Gang, Gyeong Woo;Kim, Tae Seon
    • Journal of IKEEE
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    • v.23 no.4
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    • pp.1273-1279
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    • 2019
  • Though sleep polysomnography (PSG) is considered as a golden rule for medical diagnosis of sleep disorder, it is essential to find alternative diagnosis methods due to its cost and time constraints. Recently, as the popularity of wearable health devices, there are many research trials to replace conventional actigraphy to consumer grade devices. However, these devices are very limited in their use due to the accessibility of the data and algorithms. In this paper, we showed the predictive model for sleep stages classified by American Academy of Sleep Medicine (AASM) standard and we proposed the estimation of sleep cycle by comparing sensor data and power spectrums of δ wave and θ wave. The sleep stage prediction for 31 subjects showed an accuracy of 85.26%. Also, we showed the possibility that proposed algorithm can find the sleep cycle of REM sleep and NREM sleep.

사업 포트폴리오의 기술시너지 효과 : 50대 재벌의 패널자료분석

  • 김태유;박경민
    • Journal of Technology Innovation
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    • v.5 no.1
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    • pp.15-43
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    • 1997
  • This paper investigates empirically the relationship between various business portfolio properties (particularly technological properties) and chaebol's performance using data on the 50largest chaebols in Korea. In addition to the traditional indexes to measure diversification such as entropy index, we calculated inter-industry technological similarity using R'||'&'||'D expenditure data by industry and 1990 Input-output Table in korea, and obtained chaebol-level technological relatedness and internal transaction proportion from chaebols' business profile, inter-inustry technological similarity and 1990 input-output table. We applied factor analysis on 13 business portfolio property indexes and showed that they could be grouped into 3 dimensions. diversification scope, inter-business relatedness and degree of vertical integration. In this paper, using 50 largest chaebols' financial data (1989-1994), we analyzed empirically the effect of business portfolio properties on ROS(Return On Sales) which is conventional index for firm performance and on TFP(Total Factor Productivity) growth which is a pure measure of firm performance. To utilize the advantage of panel data, FEM(Fixed Effect Model) and REM(Random Effect Model) were used. The empirical result shows that the entropy index as a measurement of inter-business relatedness in not significant but technological relatedness index is significant. OLS estimates on pooled data were considerably different from FEM or REM estimates on panel data. By introducing interaction effect among the three variables for business portfolio properties, we obtained three findings. First, only VI(Vertical integration) has a significant positive correlation with ROS. Second, when using TFP growth as an dependent variable, both TR(Technological Relatedness) and VI are significant and positively related to the dependent variable. Third, the interaction term between TR and VI is significant and negatively affects TFP growth, meaning that TR and VI are substitutes. These results suggest strategic directions on restructuring business portfolio. As VI is increased, chaebols will get more profit. A higher level of either TR or VI will increase TFP growth rate, but increase in both TR and VI will have a negative effect on TFP growth. To summarize, certain business portfolio properties such as VI and TR can be considered "resources" themselves since they can affect profit rate and productivity growth. VI and TR have a synergy effect of change in profit rate and productivity growth. VI increases ROS and productivity growth, while TR increases productivity growth representing a technological synergy effect.t.

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Treatment of Distillery Wastewater Using a Thermophilic High-Rate Hybrid Anaerobic Reactor in Industrial Scale

  • Nam, Ki-Du;Chung, In;Young, James C.;Park, Wan
    • Journal of Microbiology and Biotechnology
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    • v.9 no.6
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    • pp.737-743
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    • 1999
  • A conventional thermophilic anaerobic digester was converted into a thermophilic high-rate hybrid anaerobic reactor (THAR) for treating distillery wastewater. The THAR has been operating successfully since May 1995 at a loading rate of 5.45 to $11.52{\;}kg/\textrm{m}^3/d$ (maximum of 15.02). The THAR has demonstrated a soluble Chemical Oxygen Demand (sCOD) removal efficiency of 85 to 91% and a total COD (tCOD) removal efficiency of as much as 72 to 84%. Product gas had a methane content of 59 to 68%. The tCOD removal rates were 4.31 to 5.43, 6.26 to 6.89, and 9.03 to $9.78kg{\;}tCOD/\textrm{m}^3/d$ for tapioca, com, and naked-barley wastewater, respectively. The sCOD removal rates ranged from 3.75 to 4.79,3.28 to 4.89, and 5.57 to 6.21kg $sCOD/\textrm{m}^3/d$ for tapioca, com, and naked-barley wastewater, respectively. There were unknown substances in a naked-barley distillery wastewater that were identified as being toxic for microorganisms. However, the THAR treated naked-barley wastewater continuously for 26 days, operating at an average tCOD loading of $11.08{\;}kg/\textrm{m}^3/d$without any signs of deterioration in either COD removal efficiency or gas production rate. During this period, the average removal efficiencies of tCOD and sCOD were 84% and 91%, respectively, and the gas production rate averaged 6.61 to $7.57{\;}\textrm{m}^3/\textrm{m}^3$ reactor/d which produced 0.57 to $0.69{\;}\textrm{m}^3{\;}biogas/kg{\;}tCOD_{rem}$. From tapioca and com wastewater, the reactor showed an average gas production rate of 3.18 to 3.46 and 4.91 to $5.22{\;}\textrm{m}^3/\textrm{m}^3$ reactor/d which produced 0.53 to 0.69 and 0.62 to $0.71{\;}\textrm{m}^3/kg{\;}tCOD_{rem}$, respectively.

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