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EEG Characteristic Analysis of Sleep Spindle and K-Complex in Obstructive Sleep Apnea

  • Kim, Min Soo (Dept. of Aviation Info. & Communication Eng., Kyungwoon University) ;
  • Jeong, Jong Hyeog (Dept. of Aviation Info. & Communication Eng., Kyungwoon University) ;
  • Cho, Yong Won (Dept. of Neurology, Dongsan Medical Center, Keimyung University) ;
  • Cho, Young Chang (Dept. of Aviation Info. & Communication Eng., Kyungwoon University)
  • Received : 2017.10.13
  • Accepted : 2017.01.23
  • Published : 2017.02.28

Abstract

This Paper Describes a Method for the Evaluation of Sleep Apnea, Namely, the Peak Signal-to-noise ratio (PSNR) of Wavelet Transformed Electroencephalography (EEG) Data. The Purpose of this Study was to Investigate EEG Properties with Regard to Differences between Sleep Spindles and K-complexes and to Characterize Obstructive Sleep Apnea According to Sleep Stage. We Examined Non-REM and REM Sleep in 20 Patients with OSA and Established a New Approach for Detecting Sleep Apnea Base on EEG Frequency Changes According to Sleep Stage During Sleep Apnea Events. For Frequency Bands Corresponding to A3 Decomposition with a Sampling Applied to the KC and the Sleep Spindle Signal. In this Paper, the KC and Sleep Spindle are Ccalculated using MSE and PSNR for 4 Types of Mother Wavelets. Wavelet Transform Coefficients Were Obtained Around Sleep Spindles in Order to Identify the Frequency Information that Changed During Obstructive Sleep Apnea. We also Investigated Whether Quantification Analysis of EEG During Sleep Apnea is Valuable for Analyzing Sleep Spindles and The K-complexes in Patients. First, Decomposition of the EEG Signal from Feature Data was Carried out using 4 Different Types of Wavelets, Namely, Daubechies 3, Symlet 4, Biorthogonal 2.8, and Coiflet 3. We Compared the PSNR Accuracy for Each Wavelet Function and Found that Mother Wavelets Daubechies 3 and Biorthogonal 2.8 Surpassed the other Wavelet Functions in Performance. We have Attempted to Improve the Computing Efficiency as it Selects the most Suitable Wavelet Function that can be used for Sleep Spindle, K-complex Signal Processing Efficiently and Accurate Decision with Lesser Computational Time.

Keywords

References

  1. Tapan, D., Meena, K, Nitin, B., "Positive Airway Pressure Treatment of Adult Patients with Obstructive Sleep Apnea.," J Clin Sleep Med., Vol. 5, pp. 347-59, 2010. https://doi.org/10.1016/j.jsmc.2010.05.003
  2. Remmers, J. E., deGroot, W.J., Sauerland, E.K., "Pathogenesis of Upper Airway Occlusion During Sleep," J Appl Physiol., Vol. 44, pp. 931-38, 1978. https://doi.org/10.1152/jappl.1978.44.6.931
  3. Ihm, S.H., "Non-Dipper and Inappropriate Left Ventricular Mass in Hypertensive Patients," Korean Circulation J. Vol. 41, pp. 175-76, 2011. https://doi.org/10.4070/kcj.2011.41.4.175
  4. Sung, J.K., Kim, J.Y., "Obesity and Preclinical Changes of Cardiac Geometry and Function," Korean Circulation J., Vol. 40, pp. 55-61, 2010. https://doi.org/10.4070/kcj.2010.40.2.55
  5. Loomis, A..L., Harvey, E.N., and Hobart, G.," Potential Rhythms of Cerebral Cortex During Sleep," Vol. 81, pp. 597-598, 1935. https://doi.org/10.1126/science.81.2111.597
  6. Rechtschaffen, A., Kales, A., "A Manual of Standardised Terminology, Techniques and Scoring Systems for Sleep Stages of Human Subjects,". Washington, DC: US Government Printing Office, 1968.
  7. Ankit, P. et al., "Detection of K-complexes and Sleep Spindles (DETOKS) using Sparse Optimization," Journal of Neuroscience Methods, Vol. 251, pp. 37-46, 2015. https://doi.org/10.1016/j.jneumeth.2015.04.006
  8. Zeitlhofer, J., Gruber, G., Anderer, P., Asenbaum, S., Schimicek, P., Saletu, B.," EEG Sleep Spindles Matched Filtering," Journal of Sleep Research, Vol. 6, pp. 149-155, 1997. https://doi.org/10.1046/j.1365-2869.1997.00046.x
  9. Devuyst, S., Dutoit, T., Stenuit, P., Kerkhofs, M., "Automatic Sleep Spindles Detection Over View and Development of a Standard Proposal Assessment Method, in : Engineering in Medicine and Biology Society, EMBC, 2011 Annual International Conference of the IEEE, pp. 1713-1716, 2011.
  10. Gorur, D., "Automatic Detection of Sleep Spindles," Middle East Technical University, 2003(Master's Thesis).
  11. Akin, A., Akgul, T., "Detection of Sleep Spindles by Discrete Wavelet Transform," in Proceeding s of the IEEE 24 th Annual North east Bioengineering Conference, pp.15-17, 1998.
  12. He Youn, C., "A Study of Constructing Index Fund using Wavelet Analysis," Korea Association Information of Systems, Vol. 18, pp. 351-373, 2009.
  13. Tracey, A., Camilleri, P., Kenneth, P., Camilleri, Simon, G., "Fabri. Automatic Detection of Spindles and K-complexes in Sleep EEG using Switching Multiple Models," Biomedical Signal Processing and Control, Vol. 10, pp. 117-127, 2014. https://doi.org/10.1016/j.bspc.2014.01.010
  14. Andrzejak, R., Lehnertz, K., Mormann, F., Rieke, C., David, P., Elger, C.," Indications of Nonlinear Deterministic and Finite-Dimensional Structures in Time Series of Brain Electrical Activity: Dependance on Recording Region and Brain State," Physical Review, Vol. 64, pp. 1-8, 2001.
  15. Specht, D., "Probabilistic Neural Net Works for Classification Mapping or Associative Memory, in: Proceedings of the IEEE International Conference on Neural Networks, Vol. 1, 1988.
  16. Iasemidis, L., Shiau, D., Sackellares, J., Pardalos, P.," A Dynamical Resetting of the Human Brain at Epileptic Seizures: Application of Nonlinear Dynamics and Global Optimization Techniques," IEEE Transactions on Biomedical Engineering, Vol. 51, pp. 493-506, 2004. https://doi.org/10.1109/TBME.2003.821013
  17. Subasi, A., Yilmaz, M., Ozcalik, H.," Classification of EMG Signals using Wavelet Network," Journal of Neuroscience Methods, pp. 360-367, 1997.
  18. Zhenhu, L. et al., "Multiscale Rescaled Range Analysis of EEG Recordings in Sevoflurane Anesthesia," Clinical Neurophysiology, Vol. 123, pp. 681-688, 2012. https://doi.org/10.1016/j.clinph.2011.08.027
  19. Min, C..K., Jae, H.S.,"Implementation of an Analog Front end for EEG Signal Processing," J Korea Industr Inf Res., Vol. 18, no. 18, pp. 15-18, 2013.
  20. Homan, R.W., Herman, J., Purdy, P.," Cerebral location of International 10-20 System Electrode Placement," Electroencephalography and Clinical Neuro, Vol. 66, pp. 376-82, 1987. https://doi.org/10.1016/0013-4694(87)90206-9
  21. Kun, K., Kwangmin, A., Hyoung, L., "A Study on EEG Bionic Signals Mangement for using the Non-linear Analysis Methods," Journal of the Korea Industrial Information System Research Autumn Conference, pp. 461-467, 2002.
  22. Kun, K., Kwangmin, A., Hyoung, L.," A Study on EEG Bionic Signal Management for using the Non-linear Anlaysis Methods,"Proceedings of the Korea Society for Industrial Systems Conference, pp.461-467, 2002.
  23. Ktonas, P. Y., Golemati, S., Xanthopoulos, P., Sakkalis, V., Ortigueira, M. D. and Tsekou, H.," Time-frequency Analysis Methods to Quantify the Time Varying Microstructure of Sleep EEG Spindles: Possibility for Dementia Biomarkers?," Journal of Neuroscience Methods, Vol. 185, pp. 133-143, 2009. https://doi.org/10.1016/j.jneumeth.2009.09.001
  24. Amzica, F., Steriade, M.," The Functional Significance of K-complexes," Sleep MD Rev., Vol. 6, pp. 139-149, 2002. https://doi.org/10.1053/smrv.2001.0181
  25. Daubechies, I.," Orthonormal Bases of Compactly Supported Wavelet. Comm. Pure Appl. Math., Vol. 41, pp. 909-996, 1988. https://doi.org/10.1002/cpa.3160410705
  26. Amzica, F., Steriade, M.," The Functional Significance of K-complexes," Sleep MD Rev., Vol. 6, pp. 139-149, 2002. https://doi.org/10.1053/smrv.2001.0181