• Title/Summary/Keyword: Relevant Use

Search Result 1,718, Processing Time 0.029 seconds

A study on the development of analytical method for zinc pyrithione in cosmetics (화장품 중 zinc pyrithione 분석방법 개발에 대한 연구)

  • Jung, Jung-sul;Bae, Kyeong-mi;Son, Seung-hwan;Park, Jung-woo;Kim, Ji-hyun;Hong, Sung-taeg;Sun, Yle-shik
    • Analytical Science and Technology
    • /
    • v.28 no.3
    • /
    • pp.160-167
    • /
    • 2015
  • This study aims to develop a new analytical method to detect zinc pyrithione, the ingredient of cosmetics appointed as restricted ingredients and used as preservatives.. The analytical method was based on data gathered from the relevant literature. Information about the amounts of these ingredients was researched in order to select the base-matrix materials used to validate the analytical method. After selecting and preparing the base-matrix materials, the analytical method was validated by method validation procedures. The analytical method was verified first by inter-laboratory validation and then through analyzing the cosmetics sold in the market. Based on the results of this study, guidelines are proposed for the analysis of restricted ingredients in cosmetics, which will provide a method to test the cosmetics circulating in the Korean market. The use of the proposed guidelines will increase the quality of the cosmetics as well as the safety of human health, which will enhance the competitiveness of the Korean cosmetics industry and lead to an increase in the exportation of cosmetics.

Runoff Pattern in Upland Soils with Various Soil Texture and Slope at Torrential Rainfall Events (집중강우시 우리나라 밭토양의 토성과 경사에 따른 물유출 양상)

  • Jung, Kang-Ho;Hur, Seung-Oh;Ha, Sang-Geon;Park, Chan-Won;Lee, Hyun-Haeng
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.40 no.3
    • /
    • pp.208-213
    • /
    • 2007
  • When overland flow water is small and slow, it moves down a stream slowly and we use it as available resource. However, it could not only be good for nothing but arouse an inundation if a lot of runoff pour down to stream at a torrential rain. So it is important to know how much water to flow out and be stored in soil and on land in order to predict a flood and conserve soil and water quality. We intended to develop the prediction model of runoff in upland at a torrential rain and conducted lysimeter study in soybean cultivation and bare soil with 3 slopeness, 3 slope length and 5 soil texture from 1985 to 1991. The data of rainfall and runoff were used when daily rainfall was over 80 mm, the level of torrential rain warning. Minimum rainfall occurring runoff (MROR) was dependent on surface coverage and slope length. However soil texture and slopeness had a little influence on MROR. Runoff after MROR increased in proportion to precipitation which depended on surface coverage, soil texture and slope. Runoff ratio was larger in fine texture and bare soil than coarse soil and soybean coverage. Runoff ratio was in proportion to a square root of slope angle(radian) and reduced with slope length to converge a certain value. From these basis, we developed the prediction model following as $$Runoff(mm)=a(s^{0.5}+l^b)(Rainfall(mm)-80(1-e^{-bl}))$$ where a is a coefficient relevant soil hydraulic properties, b is a surface coverage coefficient, s is a slope angle and l is a slope length. The coefficient a was 0.5 in sandy loam and 0.6 in clay, and b was 0.06 in bare soil and 0.5 in soybean cultivation.

Drug Interactions between Cardiovascular Agents and Psychotropic Drugs (심혈관질환약물과 향정신성약물의 약물상호작용)

  • Park, Joo-Eon;Jung, Kyung-Hee
    • Korean Journal of Psychosomatic Medicine
    • /
    • v.19 no.2
    • /
    • pp.57-65
    • /
    • 2011
  • There are numerous drug interactions related to many psychotropic and cardiovascular medications. Firstly, the principles in predicting drug interactions are discussed. Cytochrome P (CYP) 450 plays a significant role in the metabolism of these drugs that are substrates, inhibitors, or inducers of CYP450 enzymes. The two most significant enzymes are CYP2D6 and CYP3A4. The ability of psychotropic drugs to act as inhibitors for the enzymes may lead to altered efficacy or toxicity of co-administered cardiovascular agents as a substrate for the enzymes. The following is also a review of the known interactions between many commonly prescribed cardiovascular agents and psychotropic drugs. Most beta blockers are metabolized by CYP2D6, which may lead to drug toxicity when they use in combination with potent CYP2D6 inhibitors including bupropion, chlorpromazine, haloperidol, selective serotonin reuptake inhibitors, and quinidine. Concomitant administration of lithium with angiotensin converting enzyme inhibitors, angiotensin receptor blockers, and diuretics may increase serum lithium concentrations and toxicity. Calcium channel blockers and cholesterol lowering agents are subject to interactions with potent inhibitors of CYP3A4, such as amiodarone, diltiazem, fluvoxamine, nefazodone, and verapamil. Prescribing antiarrhythmic drugs in conjunction with medications are known to prolong QT interval and/or inhibitors on a relevant CYP450 enzyme is generally not recommended, or needs watchful monitoring. Digoxin and warfarin also have warrant careful monitoring if co-administered with psychotropic drugs.

  • PDF

The Research on the Development Procedure and Current Problems of the Korean Abalone Industry (전복 양식업의 발전과정과 당면과제 연구)

  • Ock, Young-Soo
    • The Journal of Fisheries Business Administration
    • /
    • v.44 no.3
    • /
    • pp.15-28
    • /
    • 2013
  • Abalone aquaculture has developed very rapidly in Korea. Until the mid 1990s it has annually produced about 100 tons. Since then the yield has increased to about 9,000 tons in 2012. The amount accounts for 20% of the global abalone yield. About 86% of produced abalone is consumed domestically and the rest is exported. 100 tons for export seemed as an unattainable goal back in 2003. However, the export rose up to 1,333 tons in 2012. Despite its rapid growth, Korean abalone industry is faced with some problems. The first is the slowdown of yield increase rates. Abalone production increased by 50~60% until the mid 2000. However, the rate continued to drop to below 10%. Reasons behind the slow increase are deteriorating aquaculture grounds and worsening market problems. Constant aquaculture aggravated productivity and overcrowded facilities at a limited space made matters worse. Moreover, abalone export has stalled and so did domestic consumption. In the meantime, rising mortality of young abalone has lowered productivity at abalone breeding places. The mortality rates of abalone remained below 5% in the early 2000s but rose to 30~40% these days. This translates into rising abalone prices. The market problems imply stagnant or shrinking export as well as domestic consumption. The export increase rates took a nosedive from 200 to below 50 between the early 2000s and the late 2000s. Moreover, the increase rates of domestic consumption have become remarkably sluggish. According to, it stood at 50~60% in the mid 2000s but continued to decrease after 2008. These problems, in turn, affected the size of abalone. The usual abalone size for market was 10~12 shells per kg, but recently the size became smaller and smaller to 15~16 shells per kg. The change of size implies shift in consumption patterns: Consumers not only eat live abalone but also they cook soup with it. The size of abalone for uncooked dish is usually very big, like 10~12 shells per kg. In contrast, smaller abalone, such as 20~25 shells per kg, are used for making soup. Increasing use of smaller abalone leads to lower income of abalone aquaculture households. This is partly because that the size determines the price and the price gap between big abalones and smaller ones is extreme in Korea. For the sustainable growth of Korean abalone industry, we need to come up with strategies. First, a reasonable production system needs to be in place, especially for better management of abalone aquaculture grounds. Management of abalone licenses is also necessary because local governments issue relevant licenses as well as supervising abalone grounds. Second, abalone export destination need to be diversified. Japan, the major importer of Korean abalone, takes up a lion's share of export, at 95%. Third, new consumption style of abalone needs to be developed. Abalone used to be consumed as 'raw type' or Sashimi in Korea. This sole type of consumption hampers the growth of abalone market. Moreover, more strategies are needed to encourage and distribute home cooking of abalone rather than eating-out at restaurants. Last but not least, distribution system should be improved for better delivery of live abalone.

A User Analysis on the Improving Direction of KONEPS : Focus on Gyeongbuk province (국가종합전자조달시스템 종합쇼핑몰 개선방향에 대한 사용자분석 : 경북지역 중심으로)

  • Kim, Sang-Min;Lee, Hyun-Soo
    • Journal of Digital Convergence
    • /
    • v.16 no.5
    • /
    • pp.33-42
    • /
    • 2018
  • This paper is based on the suggestions of the prior research on the buyer feedback, the selection of various product options, and the payment procedure improvements for Korea ON-line E-Procurement System(KONEPS), and this is to confirm the necessity of improvement and satisfaction from the viewpoint of the workers of the public and subordinate organizations the purchasing and using of the computer equipment in the actual KONEPS(Korea ON-line E-Procurement System). Based on the basic questionnaires and in-depth interviews, this paper conducts the qualitative case studies on IT and non - IT workers who had purchasing experiences for equipment at public institutions and government agencies in Gyeongbuk province. As results of the study, it was confirmed that the improvement is necessary for the buyer feedback and option selection part, and that there is a difference among the work experience for the simplification of the payment procedure and the satisfaction. In addition, the biggest contribution in the provided research is to categorize and to analyze the opinions on the use of public and relevant subordinate research participants. Additional work will be needed for a large number of workers in public and subordinate organizations who have purchasing experiences for handling various procurement products and those working in the metropolitan area and other public and subordinate agencies.

Feature Ranking for Detection of Neuro-degeneration and Vascular Dementia in micro-Raman spectra of Platelet (특징 순위 방법을 이용한 혈소판 라만 스펙트럼에서 퇴행성 뇌신경질환과 혈관성 인지증 분류)

  • Park, Aa-Ron;Baek, Sung-June
    • Journal of the Institute of Electronics Engineers of Korea CI
    • /
    • v.48 no.4
    • /
    • pp.21-26
    • /
    • 2011
  • Feature ranking is useful to gain knowledge of data and identify relevant features. In this study, we proposed a use of feature ranking for classification of neuro-degeneration and vascular dementia in micro-Raman spectra of platelet. The entire region of the spectrum is divided into local region including several peaks, followed by Gaussian curve fitting method in the region to be modeled. Local minima select from the subregion and then remove the background based on the position by using interpolation method. After preprocessing steps, significant features were selected by feature ranking method to improve the classification accuracy and the computational complexity of classification system. PCA (principal component analysis) transform the selected features and the overall features that is used classification with the number of principal components. These were classified as MAP (maximum a posteriori) and it compared with classification result using overall features. In all experiments, the computational complexity of the classification system was remarkably reduced and the classification accuracy was partially increased. Particularly, the proposed method increased the classification accuracy in the experiment classifying the Parkinson's disease and normal with the average 1.7 %. From the result, it confirmed that proposed method could be efficiently used in the classification system of the neuro-degenerative disease and vascular dementia of platelet.

An Analysis on the Contents of STS in the High-School 'Science' Textbooks according to the Curriculum Revised in 2009- Focused on the Unit of 'Evolution of Life' and 'Health of Humanity and Scientific Technology' (2009 개정 교육과정에 따른 고등학교 '과학' 교과서의 STS 내용분석 - '생명의 진화'와 '인류의 건강과 과학기술' 영역을 중심으로 -)

  • Jeong, Kyeong-Ha;Son, Yeon-A;Kim, Dong-Ryeul
    • Journal of Science Education
    • /
    • v.39 no.3
    • /
    • pp.343-357
    • /
    • 2015
  • The present study aims to analyze the extent of the use of STS contents in the areas of 'Evolution of Life' and 'Health of Humanity and Scientific Technology' in 'Science' textbooks and to determine whether they meet the goals of the curriculum revised in 2009. The analysis of the 7 types of textbooks according to the STS topics areas indicated big differences between textbooks as little as 16.67% and as much as 58.33%. Also, among the topics associated with STS, 'Space Development and National Defense' and 'Environmental Problems' were not included. In the STS activity areas, the areas of 'Structured Debate,' 'Interpretation of Data,' 'Research and Investigation' showed great frequency. On the other hand, the STS activity areas of 'Field Activities,' 'Problem-solving and Decision-making,' 'Role Playing,' 'Simulation,' 'Case Study,' and 'Research Design' showed small frequency. Analysis of the STS contents for each area indicated 67.57% for the contents relevant to 'the applicability of science' accounting for the largest part whereas 'Understanding of Occupations related to Science' accounted for 1.63%, showing a great difference in their frequency. Seven standards except 'the applicability of science' were included each contents beyond 10% or less than 10% proportion. The STS contents included in the life science area of the 7 types of convergence-style 'Science' textbooks for the high-school accounted for an average of 20.75%, from as little as 12.35% to as much as 26.90%, depending on the publishes.

  • PDF

The Relationship between Adult Interpersonal Traumatic Experience and Posttraumatic Growth : The Multiple Mediating Effect of Optimism and Quality of Relationship (성인의 대인외상경험과 외상 후 성장의 관계 : 낙관성과 관계의 질의 다중매개효과)

  • Park, Euna
    • Korean Journal of Social Welfare
    • /
    • v.67 no.1
    • /
    • pp.263-288
    • /
    • 2015
  • This study is to research the mediating effects of optimism and quality of relationship which interpersonal traumatic experience influences posttraumatic growth. It focuss on verifying the impact of interpersonal traumatic experience to optimism and quality of relationship and the influence of optimism and quality of relationship to posttraumatic growth. And also it is to verify dual mediating effect between optimism and quality of relationship. Data for this study were collected through the use of a survey instrument completed by 405 interpersonal traumatic experience, 30-60 age group. Collected data were analysed by AMOS program, Structure Equation Model(SEM) was implemented to verify the mediating effect between optimism and quality of relationship. Finally, Phantom Variable was utilized for verification of indirect influence of a multi mediating effects. The findings of this study were as follows, First, the result shows that the higher level interpersonal traumatic experience, the higher posttraumatic growth they have. Second, it shows that optimism and quality of relationship have partial mediating effect between interpersonal traumatic experience and posttraumatic growth. Third, it was analyzed that optimism and quality of relationship had double mediating effect. Based on these findings, the research discussion reinforced the importance of intervene with its optimism and quality of relationship in the site of those who experience interpersonal trauma. Theological, political and practical implications of this study are as follows. First, it has a series of significance in terms of that this study confirmed its influence considering the quality of relationship from interpersonal experience among relevant factors of traumatic accident, optimism among individual factors, quality of relationship among environmental factors based on 'the crisis of life and the theory of individual growth'. econd, even though optimism and quality of relationship were proved as major predictors for posttraumatic growth of those who experience interpersonal traumatic, psychological support center for traumatic experience is not operated systematically in Korea. Third, this study implies that it should intervene mainly with its optimism and quality of relationship in the site of those who experience interpersonal trauma such as any abuses including sexual abuse, bullying, and divorce.

  • PDF

Robust Reference Intervals for Serum Kappa and Lambda Free Light Chains from a Multi Centre Study Population from Hyderabad, India: Myeloma Diagnostic Implications

  • Mohammed, Noorjahan;Chandran, Priscilla Abraham;Kandregula, Madhavi;Mattaparthi, Ratna Deepika;Gundeti, Sadasivudu;Volturi, Jyotsna;Darapuneni, Radhika;Raju, Sree Bhushan;Dattatreya, Palanki Satya
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.17 no.5
    • /
    • pp.2605-2610
    • /
    • 2016
  • The International Myeloma Working Group considers the serum free light chain (SFLC) assay to be an adjunct to traditional tests. Apart from the FLC ratio, the absolute values of individual free light chains also are gaining importance as they appear to be more relevant in certain clinical settings. Automated assays are available for their determination. As laboratories put new test systems into use catering to different disease populations, they are required by accreditation and certification bodies to verify or establish performance specifications, including reference intervals (RIs) representative of their population. Our aim was to establish local RIs for SFLC in a multicentre representative healthy population using a robust method. There was no significant relationship between SFLC levels and age, gender and creatinine levels. The 95% RI for ${\kappa}SFLC$ was 4.81 to 33.86mg/L, for ${\lambda}$ SFLC was 5.19 to 23.67mg/L and for ${\kappa}/{\lambda}SFLC$ was 0.36 to 2.33, significantly higher than the values given by the manufacturer. The ${\kappa}/{\lambda}$ SFLC ratio at 2.23, covering 100% of the data, showed 72% sensitivity (95% CI=39.0 - 94.0), 100% specificity (95% CI=71.5 - 100.0), 100% PPV (95% CI=21.5 - 100.0), 95% NPV (95% CI=75.4 - 99.9), and 79% accuracy (95% CI=56.0 - 93.0). In the patient group, kit RI for ${\kappa}/{\lambda}$ SFLC ratio classified 45.5% (n=5) as positive vs 9.1% (n=1) positive by the study RI, while the kit RI for kappa FLC classified 90.9% (n=10) as positive vs 54.5% (n=6), indicating increased probability of false positive test results with the kit RI when applied to our patient population. Appropriate and specific reference intervals and criteria values result in fewer false-positive and false-negative results which means fewer wrong or missed diagnoses.

Environmental Life Cycle Assessments on Nano-silver Inks by Wet Chemical Reduction Process (습식환원법으로 제조한 은나노 잉크의 환경 전과정 평가)

  • Lee, Young-Sang;Hong, Tae-Whan
    • Clean Technology
    • /
    • v.21 no.2
    • /
    • pp.85-89
    • /
    • 2015
  • Utilized in a variety of electronic components, electronic components industry with metallic ink technology was established itself as a major technology research and development was gradually increasing, silver ink that is excellent in conductivity and stability, have long been used in the industry of electronic components in recent years and silver ink has been the size of nanoscale particles dispersed by developing display, an electronic tag, a flexible circuit board or the like used in the semiconductor and electronics as has been highlighted in, however industry modernization of equipment by increasing the production and consumption of products generated during the production process and environmental pollutants by use of waste products is expected to bring a serious environmental problem. In this study, prepared by a wet reduction method, the manufacturing process of the silver nano-ink to the entire process of the environmental impact assessment (LCA) was evaluated using the techniques. Life cycle assessment software GaBi 6 was used as received from the relevant agencies of the silver nano-ink data with reference to the manufacturing process, building inventory was international organization for standardization (ISO) 14040, 14044 compliant LCA conducted over four stages.