• Bulletin of the Korean Chemical Society
• /
• 제20권6호
• /
• pp.667-671
• /
• 1999

A series of the para-substituted 7-aryl-norbornadienyl cation (3) was prepared in FSO3H/SO2ClF solution at -100℃ and their 13C NMR shifts were measured at -80℃. The plots of the chemical shifts (changes in chemical shifts) of cationic carbon, ΔδC+, aganist our calculated new substituent constant, σc+s, gave an excellent correlation (r=0.994), with a ρc+ value of 12.63. These results indicate that the new substituent constants, σc+s, can be successfully employed to compare the relative charge demand of the carbonium ion by π-and πσ-participation.

• 대한안전경영과학회:학술대회논문집
• /
• 대한안전경영과학회 2008년도 추계학술대회
• /
• pp.229-239
• /
• 2008

This study aims to suggest a performance measurement model reflecting the characteristics of safety evaluation system, especially the model for return manufacturing related to safety, and to develop the S-BSC(Safety-Balanced ScoreCard) measurement model using a weight lifetime value to which a relative weight is applied by using AHP based on the BSC.

• 대한약학회:학술대회논문집
• /
• 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
• /
• pp.200.1-200.1
• /
• 2003

The purpose of this study is to examine whether an brain to blood efflux system for taurine is present on the blood-brain barrier (BBB) or not and this efflux transport system is regulated by CNS cell damage with oxidative stress agent such as diethyl maleate (DEM) or tumor necrosis factor-a (TNF-${\alpha}$), by using the brain efflux index (BEI) method. The brain efflux index value is defined as the relative amount of test compound efflux from cerebrum compared with that of a reference compound, [$\^$14/C] carboxyinulin, which has limited BBB permeability. (omitted)

• 한국초지조사료학회지
• /
• 제40권3호
• /
• pp.138-148
• /
• 2020

This study was carried out to find out the changes in the growth characteristics and feed value of the three different whole-crop silage rice cultivars of whole-crop silage rice such as Jonong, Yeongwoo and Mogwoo to develop an efficient double cropping system. This study showed that there were significant differences biomass and feed values among cultivars but no clear difference among transplanting dates. Dry weight and height were in order of Mogwoo, Yeongwoo, Jonong (p<0.05). Dry weight and feed value of Jonong showed no significant difference after 21 days after heading (DAH), it was expected to be harvested before DAH 30 days. Yeongwoo showed a lower dry weight than Mogwoo, but heading date was earlier than Mogwoo, so one can expect a higher feed value than Mogwoo. Mogwoo had lower crude protein and total digestible nutrient than the other two cultivars but relative feed value in stem was higher than that of the other cultivars, but had higher dry weight than other cultivars so it was considered to take an advantage as a silage rice. Therefore, the results of this study suggest that the selection of whole-crop silage rice on the cropping system be made comprehensively by considering the heading characteristics of the cultivars and the feed value.

• 응용통계연구
• /
• 제19권3호
• /
• pp.481-504
• /
• 2006

금융위험의 측정 및 관리를 위한 도구로서 분포의 꼬리 부분과 관련한 위험척도로 VaR가 현재 널리 활용되고 있다. 특히 VaR의 정확한 추정을 위해 정규분포를 가정한 기존의 방법보다는 극단치이론을 이용한 방법이 최근 관심을 끌고 있다. 지금까지 극단치이론을 이용한VaR의 추정에 관한 연구는 대부분 단변량의 경우에 대해 이루어졌다. 본 논문에서는 코퓰러를 극단치이론에 결부시켜 다변량 극단치분포를 모형화하여 포트폴리오 위험측정을 다루고 있다. 특히 본 연구에서는 포트폴리오 위험 척도로 VaR와 더불어 ES에 대한 추정 방법도 함께 논의하였다. 포트폴리오 위험측정을 위한 방법으로 본 논문에서 논의한 코퓰러-극단치이론에 의한 접근방법이 기존의 분산-공분산 방법보다 상대적으로 우수한지를 실증자료에 대한 사후검증을 통해 살펴보았다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제15권5호
• /
• pp.2013-2020
• /
• 2014

Background: The aldehyde dehydrogenase 1 family member A1 (ALDH1A1) is one of the promising markers for identifying cancer stem cells in many cancer types, along with other markers including CD44. The aim of the present study was to evaluate the expression and clinical significance of putative cancer stem cell markers, CD44 and ALDH1A1, in a series of urothelial carcinomas of urinary bladder (UCUB) by tissue microarray (TMA). Materials and Methods: A total of 159 Urothelial Carcinomas (UC) including 96 (60%) low grade and 63 (40%) high grade carcinomas were immunohistochemically examined for the expression of CD44 and ALDH1A1. Correlations of the relative expression of these markers with clinicopathological parameters were also assessed. Results: High level expression of ALDH1A1 was found in 16% (25/159) of bladder UC which was significantly correlated with increased tumor size (p value=0.002), high grade (p value<0.001), pathologic stage (T1, p value=0.007 and T2, p value<0.001) and increased rate of recurrence (p value=0.013). A high level of CD44 expression was found in 43% (68/159) of cases, being positively correlated with histologic grade (p value=0.032) and recurrence (p value=0.039). Conclusions: Taken together, our results showed that ALDH1 was concurrently expressed in a fraction of CD44+ tumors and its expression correlated with poor prognosis in UCs. ALDH1A1 could be an ideal marker for targeted therapy of UCs in combination with conventional therapies, particularly in patients with high grade carcinomas. These findings indicate that cells expressing ALDH1A1 along with CD44 can be a potential therapeutic target in bladder carcinomas.

• 한국초지조사료학회지
• /
• 제37권2호
• /
• pp.116-124
• /
• 2017

This experiment was conducted to evaluate feed value and usability of soybean varieties as livestock forage. In this study, three soybean cultivars, OT93-26, Geomjeongsaeol, and Pungwon, were harvested at R5 (beginning seed development)- and R6 (full seed)-reproductive stages for analyzing feed value of soybean. Days to R5 stage harvest of OT93-26 among the three soybean cultivars was 55 days and the shortest while Pungwon took 103 days to reach at R6 stage. The R6-harvested soybeans had higher dry matter (DM) yields and crude protein (CP) content than the R5-harvested. However, both DM and CP were the highest in the R6-harvested Geomjeongsaeol. Contents of neutral detergent fiber (NDF) and acid detergent fiber (ADF) of Pungwon harvested at R5 were the highest whereas the R6-harvested Geomjeongsaeol had the lowest. Digestible dry matter (DDM), dry matter intake (DMI), and relative feed value (RFV) of the R6-harvested Geomjeongsaeol and Pungwon were higher than those of the R5-harvested, but in case of OT93-26, those at R6 stage were low rather than those at R5 stage. However, soybean could be used as alternative forage with high feed value for livestock. Taken together, Geomjeongsaeol could be used for developing new forage soybean varieties with high feed value, and R6 would be the optimum harvesting stage for yield and quality of forage soybean.

• Journal of Animal Science and Technology
• /
• 제63권5호
• /
• pp.1098-1113
• /
• 2021

Maturation process of alfalfa (Medicago sativa L.) could be prevented by the reduction of lignin content in terms of conventional breeding or transgenic technology. Alfalfa could exhibit higher leaf/stem ratio, with a concern of yield loss. The objective of this study was to compare forage yield and nutritive value of low lignin alfalfa and two reference varieties subjecting to two harvest intervals and three seeding rates. The experimental design was a randomized complete block in a split-split plot arrangement with four replicates, where harvest intervals (28-day and 35-day) were assigned to whole plots, seeding rates were subplots, and varieties were sub-subplots. The weighted mean nutritive value was applied to two production years of 2016 and 2017. Hi-Gest 360 (low lignin alfalfa) provided similar yield potential and increased nutritive value compared to two reference varieties. Over a two-year production period, alfalfa harvested at every 28-day interval provided more economic returns than those at 35-day interval. For the seeding year and first production year, five cuts made by the 28-day interval produced more yield than four cuts by the 35-day interval. Due to limited rainfall in May 2017, a sharp drop of the first cutting overturned the advantage of the five-cut system. Shorter intervals between harvests generally increased crude protein (CP) concentrations. The differences of relative feed value (RFV) between two harvest intervals tended to be great during the first and second cuttings. Overall, harvest interval had a large effect on nutritive value and a more significant effect on alfalfa dry matter yield than variety selection. Seeding rate did not affect alfalfa yield and nutritive value.

• 한국초지조사료학회지
• /
• 제41권4호
• /
• pp.280-286
• /
• 2021

The objective of this study was to prove the effect of pig slurry application with charcoal on nitrogen use efficiency (NUE), feed value and ammonia (NH₃) emission from maize forage. The four treatments were applied: 1) non-pig slurry (only water as a control), 2) only pig slurry application (PS), 3) pig slurry application with large particle charcoal (LC), 4) pig slurry application with small particle charcoal (SC). The pig slurry was applied at a rate of 150 kg N ha^-1, and the charcoal was applied at a rate of 300 kg ha-1 regardless of the size. To determine the feed value of maize, crude protein, dry matter intake, digestible dry matter, total digestible nutrient, and relative feed value were investigated. All feed value was increased by charcoal treatment compared to water and PS treatment. Also, the NUE for plant N was significantly higher in charcoal treatments (LC and SC) compared to PS treatment. On the other hand, there is no significant difference for feed value and NUE between LC and SC. The NH₃ emission was significantly reduced 15.2% and 27.9% by LC and SC, respectively, compared to PS. Especially, SC significantly decreased NH₃ emission by 15% compared to LC. The present study clearly showed that charcoal application exhibited positive potential in nitrogen use efficiency, feed value and reducing N losses through NH₃ emission.

• Journal of Magnetics
• /
• 제2권1호
• /
• pp.12-15
• /
• 1997

Fe-(3∼6.5wt%) Si alloy powders having a high magnetic induction(Bs) and a low core loss value for high frequency use were obtained by an extractive melt spinning as well as a centrifugal atomization technique. Sintered core rings made by the rapidly solidified Fe-6.5wt% Si powders exhibited the high frequency magnetic properties : megnetic induction(B8) of 1.23 T, coercivity(Hc) of 0.12 Oe, relative permeability(${\mu}$a) of 6321, and core loss(W10/50) of 1.27 W/kg from the rings of 1.1 mm thick. The magnetic induction values were found to be almost identical to those of non-oriented Fe-6.5wt% Si steel sheet and double the value of 6.5wt% Si sheet prepared by the CVD technique. The high frequency core losses(W) up to 10 kHz(W10/10k) were measured to be competitive to those of grain-oriented Fe-6.5wt% Si steel sheet.