• Nuclear Engineering and Technology
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• v.28 no.2
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• pp.129-136
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• 1996

Influence diagram method is applied to containment performance analysis of Young-Gwang 3&4 in an effort to overcome some drawbacks of current containment performance analysis method. Event tee methodology has been adopted as a containment performance analysis method. There are, however, some drawbacks on event tree methodology. This study is to overcome three major drawbacks of the current containment performance analysis method : 1) Event tree cannot express dependency between events explicitly. 2) Accident Progression Event Tree (APET) cannot represent entire containment system. 3) It is difficult to consider decision making problem. To resolve these problems, influence diagrams, is proposed. In the present ok, the applicability of the influence diagrams has been demonstrated for YGN 3&4 containment performance analysis and accident management strategy assessments of this study are in good agreement with those of YGN 3&4 IPE. Sensitivity analysis has been peformed to identify relative important variables for each early containment failure, late containment and basemat melt-though. In addition, influence diagrams are used to assess two accident management strategies : 1) RCS depressurization, 2) cavity flooding. It is shown that influence diagrams can be applied to the containment performance analysis.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.238-238
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• 2017

Salt stress is one of the deteriorating abiotic stresses due to the climate change, which causes over-accumulation of $Na^+$ and $Cl^-$ ions in plants and inhibits the growth and yield of rice especially in coastal Southeastern Asia. The yield components of rice plant (panicle number, spikelet number per panicle, 1000-grain weight, % of ripened grains) that are majorly affected by salt stress vary with growth stages at which the plant is subjected to the stress. In addition, the salt sensitivity of each yield component differs among rice varieties even when the salt-affected growth stage was same, which indicates that the physiological mechanism to maintain each yield component is different from each other. Therefore, we hypothesized that rice plant has different genes/QTLs that contribute to the maintenance of each yield component. Using a Japanese leading rice cultivar, Koshihikari, and salt-tolerant Nona bokra's chromosome segment substitution lines (CSSLs) with the genetic background of Koshihikari (44 lines in total) (Takai et al. 2007), we screened higher yielding CSSLs under salinity in comparison to Koshihikari and identified the yield components that were improved by the introgression of chromosome segment(s) of Nona bokra. The experiment was conducted in a salinized paddy field. One-month-old seedlings were transplanted into a paddy field without salinity. These were allowed to establish for one month, and then the field was salinized by introducing saline water to maintain the surface water at 0.4% salinity until harvest. The experiments were done twice in 2015 and 2016. Although all the CSSLs and Koshihikari decreased their yield under salinity, some CSSLs showed relatively higher yield compared with Koshihikari. In Koshihikari, all the yield components except panicle number were decreased by salinity and % of ripened grains was mostly reduced, followed by spikelet number per panicle and 1000-grain weight. When compared with Koshihikari, keeping a higher % of ripened grains under salinity attributed to the significantly greater yield in one CSSL. This indicated that the % of ripened grains is the most sensitive to salt stress among the yield components of Koshihikari and that the Nona bokra chromosome segments that maintained it contributed to increased yield under salt stress. In addition, growth analyses showed that maintaining relative growth rate in the late grain filling stage led to the increased yield under salt stress but not in earlier stages.

• Journal of Environmental Impact Assessment
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• v.22 no.6
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• pp.547-556
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• 2013

Recently, golf courses have increased over the years because golf became popular leisure sport. Various environmental problems have been then issued by a golf course during constructing and running them. A problem of pesticide, which is serious among various environmental problems, from golf course has harmful effect on surrounding area and makes human suffer from acute and chronic diseases. Pesticides are used for the cost-effective managing of golf course and the amount of pesticides also increases as the number of golf course increase. Since the assessment of pesticides on near-by surrounding has been focused on water and soil media, studies related to atmospheric dispersion have been hardly attempted. The method to assess an impact of pesticide nearby agricultural production by the atmospheric dispersion using AGDISP(AGricultural DISPersal) model was developed and applied to the actual planned golf course located in Hongcheon, Gangwon. For implementing AGDISP, parameters were investigated from the golf course's land use planning map, pesticide spray device, Hong-Cheon weather station and etc. First of all, a kind of pesticide, a form of spraying pesticide, geographical features, weather data, and distance(golf course to plantation) were investigated to understand how to work these parameters in AGDISP. Restricted data(slope angle, droplet size distribution and solar insolation) sensitivity analysis of these parameters to estimate effect of pesticide nearby a plantation and a high relative contribution data of analyzed data was selected for input data. Ethoprophos was chosen as the pesticide used in the golf course and the amounts of pesticide deposition per annual agricultural productions were predicted. The results show that maximum amount of pesticide deposition through atmospheric dispersion was predicted $2.32{\mu}/m^2$ at 96 m where the nearest organic plantation exists. The residues of pesticide were also estimated based on the annul production of the organic and the deposition amount of the pesticide. Consequently, buckwheat, wheat and millet were likely to exceed maximum residue limits for pesticides in foods(MRL) and sorghum, corn and peanut were likely to exceed MRL by organic farming as well.

• Journal of the korean academy of Pediatric Dentistry
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• v.39 no.4
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• pp.390-396
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• 2012

Infraocclusion is defined as tooth whose relative occlusal movement was blocked during the period of active eruption due to ankylosis and so on. Then infraoccluded tooth remains under the occlusal plane composed by adjacent structures showing normal eruption patterns. Untreated infraocclusion may cause: prolonged retention of infraoccluded teeth; extrusion of apposed teeth; destruction of periodontal tissues by occlusal force and food packing; increased sensitivity for dental caries; and disturbances on eruption pathway of succedaneous teeth. Therefore, periodic check-ups and proper treatments are required. There are many treatment options on infraoccluded deciduous molars such as periodic observation, conservative method, restoration and space regaining with extraction of the teeth. The choice of treatment may depend on the presence of succedaneous teeth, time of diagnosis and degree of infraocclusion. In this case report, three patients showing displacement of the second premolars due to infraocclusion of upper second primary molars, were treated by means of space regaining with removable orthodontic appliances and extraction of ankylosed primary molars. All malpositioned permanent premolars in the 3 cases showed ordinary eruption pathways after treatment.

• Journal of Korea Water Resources Association
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• v.53 no.10
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• pp.871-876
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• 2020

Understanding the wave characteristics near the outlet of coastal power plants for cooling water in the vicinity of the dredged areas is critically important for the construction and operation of the plants. By Employing the eigenfunction expansion method, in this study, we analyzed the reflection of monochromatic water waves over (1) shear currents near the outlet and (2) multi-arrayed trenches representing dredged areas. We firstly optimized the number of grids expressing shear currents and the number of evanescent modes based on a convergence test. We then analyzed the sensitivity of the reflection coefficients depending on (1) magnitude of shear currents, (2) width of shear currents, (3) a distance between adjacent trenches, and (4) a number of trenches. The results showed that the reflection coefficient was more sensitive to the number of trenches and the distance between trenches than the velocity of shear currents and the width of shear currents. We also found that even the effect of shear currents is relatively small, the effect is not negligible in a relative water depth from shallow to near shallow water waves (0.01 < kh ≦ 0.70).

• Journal of the Korean association of regional geographers
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• v.21 no.4
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• pp.751-763
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• 2015

Both the selection of indicators and weights for them are critical issues in the vulnerability assessment. This study is to assess the air pollution vulnerability focused on ozone for 249 local jurisdictions using weights calculated by the entropy methodology and then examine the applicability of the methodology. We selected indicators for air pollution vulnerability assessment and standardized them. Subsequently, we calculated weights of each indicator using the entropy method and then integrated them into the vulnerability index. The exposure indicators consider meteorological and air pollution factors and the sensitivity of the local jurisdiction include variables on vulnerable areas and environments. The adaptive capacity contains socio-economic characteristics, health care capacities and air pollution managemental factors. The results show that Hwaseong-si, Gwangjin-gu, Gimpo-si, Gwangju-si, Gunpo-si are among the highest vulnerabilities based on the simple aggregation of indicators. And vulnerability-resilience (VRI) aggregation results indicates the similar spatial pattern with the simple aggregation outcomes. This article extends current climate change vulnerability assessment studies by adopting the entropy method to evaluate relative usefulness of data. In addition, the results can be used for developing customized adaptation policies for each jurisdiction reflecting vulnerable aspects.

• Development and Reproduction
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• v.20 no.4
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• pp.315-329
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• 2016

Fas ligand (FasL) and its receptor Fas have been implicated in granulosa cell apoptosis during follicular atresia. Although interferon-gamma (IFN-${\gamma}$) is believed to be involved in the regulation Fas expression in differentiated granulosa or granulosa-luteal cells, the expression of this cytokine and its role in the regulation of the granulosa cell Fas/FasL system and apoptosis during follicular maturation have not been thoroughly investigated. In the present study, we have examined the presence of IFN-${\gamma}$ in ovarian follicles at different stage of development by immunohistochemistry and related their relative intensities with follicular expression of Fas and FasL, and with differences in granulosa cell sensitivity to Fas activation by exogenous agonistic Anti-Fas monoclonal antibody (Fas mAb). Although IFN-${\gamma}$ immunostaining was detectable in oocyte and granulosa cells in antral follicles, most intense immunoreactivity for the cytokine was observed in these cells of preantral follicles. Intense immunoreactivity for IFN-${\gamma}$ was most evident in granulosa cells of atretic early antral follicles where increased Fas and FasL expression and apoptosis were also observed. Whereas low concentrations of IFN-${\gamma}$ (10-100 U/mL) significantly increased Fas expression in undifferentiated granulosa cells (from preantral or very early antral follicles) in vitro, very higher concentrations (${\geq}1,000U/mL$) were required to up-regulate of Fas in differentiated cells isolated from eCG-primed (antral) follicles. Addition of agonistic Fas mAb to cultures of granulosa cells at the two stages of differentiation and pretreated with IFN-${\gamma}$ (100 U/mL) elicited morphological and biochemical apoptotic features which were more prominent in cells not previously exposed to the gonadotropin in vivo. These findings suggested that IFN-${\gamma}$ is an important physiologic intra-ovarian regulator of follicular atresia and plays a pivotal role in regulation of expression of Fas receptor and subsequent apoptotic response in undifferentiated (or poorly differentiated) granulosa cells at an early (penultimate) stage of follicular development.

• Analytical Science and Technology
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• v.25 no.1
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• pp.39-49
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• 2012

A method to detect 37 volatile organic compounds (VOCs) in surface water was described based on headspace solid-phase micro extraction and gas chromatography-mass spectrometry. VOCs in water were vaporized for 30 min at 40 $^{\circ}C$ in a headspace vial and adsorbed on 85 ${\mu}m$ carboxen-polydimethylsiloxane. Under the established condition, the lowest quantification limit was 4.1-96 ng/L by using 4.0 mL water sample, and the relative standard deviation was less than 15% at concentrations of 0.05 and 0.50 ${\mu}g/L$. The detection limits meet lower concentration than 1/10 of the water quality criteria for VOCs established by the US EPA or Germany. The LOQ is a sensitivity which the monitoring for the establishing water quality criteria requires. When the proposed method was used to analyze the target compounds in sixteen surface water samples and total 16 VOCs were detected in surface water samples collected from Gum-River. Maximum concentrations of VOCs detected were not exceeded the EPA or Germany guidelines in any of the samples.

• Journal of Food Hygiene and Safety
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• v.3 no.2
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• pp.65-73
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• 1988

T-2 toxin is one of mycotoxins produced by fungi such as Fusarium spp. and possesses a potent cytotoxicity to eukaryotic cell. The contamination of mycotoxins in cereals and feedstuffs is one of the great concerns in health authorities. Therefore, the development of the specific, sensitive and simplified analysis method for T -2 toxin is required. During more than ten years, several chemical and biological analysis methods were proposed and applied for the detection and quantification of T-2 toxin. TLC, GLC-FID and GC-MS are widely employed, but these methods required numerous clean-up procedures before analysis, and the detection limit for T-2 toxin is more than 10 ppb. Biological analysis methods with dermal tissues and cultured cells are not specific to T-2 toxin, since T-2 toxin and other related derivatives possess a similar toxicological activity although their relative activity is different each otber. Based on tbe specific reaction between antibody and antigen, the authors tried to introduce the immunochemical methods for determination of T-2 toxin. The enzyme-linked immunosorbent assay method using monoclonal antibody for T-2 toxin was applied to analyse T-2 toxin. The detection limit of T-2 toxin by ELISA method was 0.1 ppb. The correlation between ELISA and GC-MS method on these samples was very high. ELISA method developed for the detection and quantification of T -2 toxin in this paper possesses simplicity, high sensitivity and specific for T-2 toxin. Furthermore, the ELISA method with T-2 toxin monoclonal antibody was an excellent tool for the screening of Fusarium spp. which was suspected to produce T-2 toxin.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.4 no.1
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• pp.71-76
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• 2001

Purpose: Many diagnostic modalities for neonatal cholestasis have shown features that are helpful, however until recently none of them are not pathognomonic of biliary atresia (BA). We carried out a prospective study of infants with cholestatic jaundice with the aim of establishing an efficient method of diagnosing BA. Methods: Twenty-seven consecutive infants with cholestatic jaundice were enrolled in this study and ranged from 7 to 152 days in age (mean; $51.2{\pm}34.2$ days). Gastroduodenoscopy was carried out using a fiberscope (Olympus N30). All the babies were fasted for at least 4 hours before the procedure and 20 ml of 10% dextrose solution was given at the time of endoscopy. The endoscopic examination focused on the 5 minutes observation of the evidence of biliary secretion. If there was lack of the evidence of the biliary secretion, endoscopy was removed and repeated the examination with some pause. Results: There are lack of the evidence of biliary secretion in all infants with BA. In non-BA group, 8 out of the 10 infants showed biliary secretion on the first trial, however one (Alagille syndrome) of the two infants without evidence of biliary secretion, finally exhibited biliary secretion on the second trial. The above observations resulted in the diagnostic accuracy of 96.3% with 100.0% sensitivity and 90.0% specificity. Conclusion: In light of the results from our relatively small study, endoscopy is a convenient, and relative inexpensive procedure. we strongly support the use of endoscopy for the diagnosis of BA in the screening and evaluation of infantile cholestasis.