• Clinical and Experimental Pediatrics
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• v.56 no.12
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• pp.534-539
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• 2013

Purpose: Electroencephalography (EEG) is frequently ordered for patients with febrile seizures despite its unclear diagnostic value. We evaluated the prevalence of abnormal EEGs, the association between clinical findings and abnormal EEGs, and the predictive value of EEG for the recurrence of febrile seizures Methods: Data were collected on 230 children who were treated for febrile seizures at Kyung Hee University Medical Center from 2005 to 2009. EEGs were recorded after 1-2 days of hospitalization when children became afebrile. EEG patterns were categorized as normal, epileptiform, or nonspecific relative to abnormalities. The patients' medical records were reviewed, and telephone interviews with the families of the children were conducted to inquire about seizure recurrence. The relationships between clinical variables, including seizure recurrence, and EEG abnormalities were evaluated. Results: Of the 131 children included, 103 had simple and 28 had complex febrile seizures. EEG abnormalities were found in 41 children (31%). EEG abnormalities were more common in children with complex than simple febrile seizures (43% vs. 28%), but the difference was not statistically significant. Logistical regression analysis showed that having multiple seizures in a 24-hour period was significantly predictive of abnormal EEG (odds ratio, 2.98; 95% confidence interval, 1.0 to 88; P =0.048). The frequency of recurrence did not differ significantly in the normal (31%) and abnormal (23%) EEG groups. Conclusion: Multiple seizures within 24 hours were predictive of abnormal EEG in children with febrile seizures. Abnormal EEG was not predictive of febrile seizure recurrence.

• Journal of Acupuncture Research
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• v.20 no.5
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• pp.28-37
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• 2003

Objective & Methods: In order to ascertain the names. locations. the way of getting acu-point and indications for moxibustion about Ko-Hwang(膏盲) and Go-Hwang-Su(膏盲兪). I have translated the text for Ko-Hwang(膏盲) and Go-Hwang-Su(膏盲兪) collected in several relative classical books. and performed literal investigation about it. Through the study, the following results are obtained. Results & Conclusions: 1. The two words Go(膏) and Hwang(盲) have different concepts each other originally. and Go-Hwang(膏盲) is the abbreviation of the words "Upon the Hwang(盲), Under the Go(膏)", which means "A gap of Heart and diaphragm" that is under the heart and on the diaphragm 2. Go-Hwang-Su(膏盲兪) is the acu-point which can treat the diseases located in the gap of Go(膏) and Hwang(盲), so they must not be named as Go-Hwang(膏盲) or Go-Hwang-Hyui(膏盲穴). 3. The origination of Go-Hwang-Su(膏盲兪) is speculated as the interval of Hwang-Bo-Mil(皇甫謐) and Son-Sa-Mak(孫思邈). And I think it had been created by Son-Sa-Mak(孫思邈) up to now. 4. The words "Four ribs and Three spaces(四肋三間)" those are founded in the text of The Entrance of Medicine(醫學入門) and The Great Success on Acupuncture and Moxibustion(針灸大成) are either the words those had been quoted from The Bible of Helping Life by Acupucture and Moxibustion(針灸資生經) in wrong way. or the misunderstanding of the original mind of Son-Sa-Mak(孫思邈) as being quoted in the text. So you should know it exactly as Son-Sa-Mak(孫思邈) had said. 5. When you search the acu-point Go-Hwang-Su(膏盲兪), you must pull the arms of patients forwardly to reveal the acu -point. because it is covered by the scapula in normal posture. 6. The indications for the use of Go-Hwang-Su(膏盲兪) are same as mentioned in this study. And it can grow the Yang-Gi(陽氣) more prosperous.

• Korean journal of applied entomology
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• v.42 no.3
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• pp.233-240
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• 2003

The effect of density suppression of Amblyseius fallacis (Garman) against Panonychus citri (McGregor) on citrus tree introduced with some different ratio was investigated. When it was introduced with over 16:1 (Panonychus citri: A. fallacis) ratio, Panonychus citri was suppressed very effectively. And in case of introduced once or two times with 20: 1 ratio when the density of Panonychus citri was reached 0.5 and 1.0 per leaf, the density of A. fallacis was formed highly, but the suppression effect against Panonychus citri was not effective. Also, the density changes of P. citri and A. fallacis on the citrus tree released with 10: 1 ratio (P. citri: A. fallacis) when the density of P. citri was reached about 0.1 per leaf in plastic film house were investigated. In case of released twice at the interval of 10 days, the density of A. fallacis was high and P. citri was suppressed so effectively over two month. On the inside of canopy of the citrus tree planted in plastic film house, the air temperature was much lower than on the outside of canopy, while relative humidity was much higher.

• Tuberculosis and Respiratory Diseases
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• v.80 no.2
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• pp.179-186
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• 2017

Background: Although the World Health Organization (WHO) classification of lung squamous cell carcinoma (SCC) was revised in 2015, its clinical implications for lung SCC subsets remain unclear. We investigated whether the morphologic characteristics of lung SCC, including keratinization, were associated with clinical parameters and clinical outcome of patients. Methods: A total of 81 patients who underwent curative surgical resection of diagnosed lung SCC, were enrolled in this study. Attributes such as keratinization, tumor budding, single cell invasion, and nuclear size within the tumor, as well as immunohistochemistry of Bcl-xL and pS6 expressions, were evaluated. Results: The keratinizing and nonkeratinizing subtypes did not differ with respect to age, sex, TNM stage, and morphologic parameters such as nuclear diameter, tumor budding, and single cell invasion at the tumor edge. Most patients with the keratinizing subtype (98.0%) had a history of smoking, whereas the nonkeratinizing group had a relatively higher proportion of never-smokers relative to the keratinizing group (24.0% vs. 2.0%; p=0.008, chi-square test). Expression of pS6 (a surrogate marker of mammalian target of rapamycin complex 1 [mTORC1] signaling that regulates keratinocyte differentiation), and Bcl-xL (a key anti-apoptotic molecule that may inhibit keratinization), did not correlate significantly with the presence of keratinization. Patients with the keratinizing subtype had a significantly shorter overall survival (85.2 months vs. 135.7 months, p=0.010, log-rank test), and a multivariate analysis showed that keratinization was an independent, poor prognostic factor (hazard ratio, 2.389; 95% confidence interval, 1.090-5.233; p=0.030). Conclusion: In lung SCC, keratinization is associated with a poor prognosis, and might be associated with smoking.

• Journal of Digital Convergence
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• v.13 no.10
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• pp.313-318
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• 2015

A traditional speech enhancement methods distort the sound spectrum generated according to estimation of the remaining noise, or invalid noise is a problem of lowering the speech recognition performance. In this paper, we propose a speech detection method that convergence the sound energy distribution process and sound energy parameters. The proposed method was used to receive properties reduce the influence of noise to maximize voice energy. In addition, the smaller value from the feature parameters of the speech signal The log energy features of the interval having a more of the log energy value relative to the region having a large energy similar to the log energy feature of the size of the voice signal containing the noise which reducing the mismatch of the training and the recognition environment recognition experiments Results confirmed that the improved recognition performance are checked compared to the conventional method. Car noise environment of Pause Hit Rate is in the 0dB and 5dB lower SNR region showed an accuracy of 97.1% and 97.3% in the high SNR region 10dB and 15dB 98.3%, showed an accuracy of 98.6%.

• Journal of Preventive Medicine and Public Health
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• v.34 no.3
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• pp.253-261
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• 2001

Objectives : To evaluate the hypothesis that air pollution could increase emergency room visits for respiratory diseases, and if so, to quantify the strength of association between those. Methods : We compiled daily records of hospital emergency room visits for respiratory diseases in Seoul, from November 1. 1955 to October 31. 1996, by using medical utilization data of unscheduled visits. In addition, air quality and weather data for the same period was collected. And a case-crossover design was applied by adopting conditional logistic regression analysis to determine the relationship between air pollutants and emergency room visits for respiratory diseases. In particular, the control periods were chosen by a bidirectional paired matching technique 7, 14, and 21 days before and after the case periods. Results : Only ozone was associated with the increased number of emergency room visits for respiratory diseases. The relative risk according to a 30ppb increase of ozone concentration (24hr mean, lagged 1day) was 1.91(95% confidence interval = 1.78-2.05). Conclusion : There was a statistically significant association between the ambient ozone and daily emergency room visits for respiratory diseases.

• Speech Sciences
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• v.9 no.1
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• pp.17-26
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• 2002

Voice onset time (VOT) is defined as the time interval from the oral release of a stop consonant to the onset of glottal pulsing in the following vowel. VOT is a temporal characteristic of stop consonants that reflects the complex timing of glottal articulation relative to supraglottal articulation. There have been many reports on efforts to clarify the acoustical and physiological properties that differentiate the three types of Korean stops, including acoustic, fiberscopic, aerodynamic and electromyographic studies. In the acoustic and fiberscopic studies for stop consonants, the voice onset time and glottal width during the production of stops has been known as the longest and largest in the heavily aspirated type followed by the slightly aspirated type and unaspirated types. The thyroarytenoid and posterior cricoarytenoid muscles were physiologically inter-correlated for differentiating these types of stops. However, a review of the English literature shows that the fine movement of the mucosal edges of the vocal folds during the production of stops has not been well documented. In recent. years, a new method for high-speed recording of laryngeal dynamics by use of a digital recording system allows us to observe with fine time resolution. The movements of the vocal fold edges were documented during the period of stop production using a fiberscopic system of high speed digital images. By observing the glottal width and the visual vibratory movements of the vocal folds before voice onset, the heavily aspirated stop was characterized as being more prominent and dynamic than the slightly aspirated and unaspirated stops.

• Genomics & Informatics
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• v.14 no.4
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• pp.196-204
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• 2016

Many researchers have found that one of the most important characteristics of the structure of linkage disequilibrium is that the human genome can be divided into non-overlapping block partitions in which only a small number of haplotypes are observed. The location and distribution of haplotype blocks can be seen as a population property influenced by population genetic events such as selection, mutation, recombination and population structure. In this study, we investigate the effects of the density of markers relative to the full set of all polymorphisms in the region on the results of haplotype partitioning for five popular haplotype block partition methods: three methods in Haploview (confidence interval, four gamete test, and solid spine), MIG++ implemented in PLINK 1.9 and S-MIG++. We used several experimental datasets obtained by sampling subsets of single nucleotide polymorphism (SNP) markers of chromosome 22 region in the 1000 Genomes Project data and also the HapMap phase 3 data to compare the results of haplotype block partitions by five methods. With decreasing sampling ratio down to 20% of the original SNP markers, the total number of haplotype blocks decreases and the length of haplotype blocks increases for all algorithms. When we examined the marker-independence of the haplotype block locations constructed from the datasets of different density, the results using below 50% of the entire SNP markers were very different from the results using the entire SNP markers. We conclude that the haplotype block construction results should be used and interpreted carefully depending on the selection of markers and the purpose of the study.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.26 no.2
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• pp.129-137
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• 2008

This study focuses on the radiometric normalization, which is one of the pre-processing steps to apply the change detection technique fur hyperspectral images. The PIFs which had radiometric consistency under the time interval were automatically extracted by applying spectral angle, and used as sample pixels for linear regression of the radiometric normalization. We also dealt with the problem about the number of PIFs for linear regression with iteratively quantitative methods. The results were assessed in comparison with image regression, histogram matching, and FLAASH. In conclusion, we show that linear regression method with PIFs can carry out the efficient result for radiometric normalization.

• Journal of Veterinary Clinics
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• v.30 no.1
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• pp.12-16
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• 2013

This study was performed to investigate hepatoprotective effect of rutin on acute hepatic damage induced by carbon tetrachloride in rats. Twenty-four male Sprague-Dawley rats were randomly divided into four groups; normal control group, $CCl_4$ control group, two rutin treatment groups (rutin 200+$CCl_4$ and rutin 400+$CCl_4$). Dissolving vehicles were applied to the rats in the normal control group. The rutin was administrated to the rats in rutin 200+$CCl_4$ and rutin 400+$CCl_4$ groups at the levels of 200 mg/kg and 400 mg/kg, 3 consecutive days orally, with 24 hours interval before inoculating $CCl_4$. $CCl_4$ was intraperitoneally administered an hour after the last treatment of rutin to the rats in every group except the normal control group. The body weight of rats in $CCl_4$ control group were significantly lower than other groups (p < 0.05), but the liver weight and relative liver weight were higher than normal control group (p < 0.05). The activities of ALT, AST, ALP, GTP, LDH and the level of total bilirubin in sera of rats in $CCl_4$ control group were higher and the levels of total protein, albumin and globulin were lower than the normal group (p < 0.05). The activities of ALT, AST, ALP, GTP, LDH and the level of total bilirubin in rutin 200+$CCl_4$ and rutin 400+$CCl_4$ groups were lower than $CCl_4$ control group (p < 0.05). Therefore the pre-treatment of rutin before $CCl_4$ inoculation in rats effectively inhibited the elevation of serum ALT, AST and total bilirubin which are the parameters of hepatic damage.