• Biomolecules & Therapeutics
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• 제26권1호
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• pp.81-92
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• 2018

It is widely accepted that altered metabolism contributes to cancer growth and has been described as a hallmark of cancer. Our view and understanding of cancer metabolism has expanded at a rapid pace, however, there remains a need to study metabolic dependencies of human cancer in vivo. Recent studies have sought to utilize multi-modality imaging (MMI) techniques in order to build a more detailed and comprehensive understanding of cancer metabolism. MMI combines several in vivo techniques that can provide complementary information related to cancer metabolism. We describe several non-invasive imaging techniques that provide both anatomical and functional information related to tumor metabolism. These imaging modalities include: positron emission tomography (PET), computed tomography (CT), magnetic resonance imaging (MRI), magnetic resonance spectroscopy (MRS) that uses hyperpolarized probes and optical imaging utilizing bioluminescence and quantification of light emitted. We describe how these imaging modalities can be combined with mass spectrometry and quantitative immunochemistry to obtain more complete picture of cancer metabolism. In vivo studies of tumor metabolism are emerging in the field and represent an important component to our understanding of how metabolism shapes and defines cancer initiation, progression and response to treatment. In this review we describe in vivo based studies of cancer metabolism that have taken advantage of MMI in both pre-clinical and clinical studies. MMI promises to advance our understanding of cancer metabolism in both basic research and clinical settings with the ultimate goal of improving detection, diagnosis and treatment of cancer patients.

• 보건교육건강증진학회지
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• 제28권3호
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• pp.113-128
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• 2011

Objectives: The purpose of this study was to investigate the current state and trends of health-related research on foreign migrants living in Korea. Methods: Among 85 articles identified via PubMed and RISS and additional 7 articles by ancestry search, 28 were selected for the review. Two authors independently reviewed the articles using a literature review matrix and examined together the three aspects of the studies: research methods, research topics, and research results. Results: Most of the articles were published between 2005-2009, and only 3 studies used an interdisciplinary approach. Most were exploratory and there were 4 intervention studies: three of them examined the effect of an art therapy on acculturative stress and mental health among marriage migrant women. The lack of information on informed consent, approval of institutional review board, and the validity/reliability of the translated instruments were noted. Conclusions: Research is needed to examine migrants' health behaviors, the prevalence of chronic illness among migrants, and the influence of acculturation on the use of health resources, health behaviors, and health status. Researchers should be aware of ethnic issues when they work with foreign migrants.

• 대한수학교육학회지:수학교육학연구
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• 제22권1호
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• pp.39-52
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• 2012

교사의 교수를 위한 수학적 지식에 관한 연구는 최근 몇년동안 서서히 발전하고 있다. 교사가 수학을 가르치기 위해 필요한 지식이 무엇인가에 대한 다양한 해석과 함께, 교사의 교수를 위한 수학적 지식이 어떻게 학생 성취도와 관련되어 있는 지를 밝히려는 연구들도 역시 이루어 지고 있다. 이 논문은 교수를 위한 수학적 지식에 관한 다양한 해석들과 이 지식과 학생들의 성취도간의 관계를 조사한 연구들을 고찰하고, 이 주제를 연구하는데 어려움들이 무엇인지 밝힌다. 또한, 이 연구는 관련 문헌 연구에 기초하여, 교사의 교수를 위한 수학적 지식과 학생들의 성취도에 관한 가능한 연구 주제 및 연구 방법을 제안한다.

• 한방안이비인후피부과학회지
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• 제33권1호
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• pp.25-44
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• 2020

Objective : The purpose of this study is to investigate the use of probiotics for cure of atopic dermatitis and suggest for the better method of studies in order to seek more effective treatment. Methods : We searched from Korean Traditional Knowledge Portal(KTKP), Reserach Information Sharing Service(RISS), National Discovery for Science Leader(NDSL) and PubMed. We selected among the papers published from 2005 to 2019 using terms related to 'Atopic dermatitic & Allergy diseases & Probiotics'. Results : 41 papers were selected from the database worldwidely. In these collected 41 related theses, there were 14 experimental studies(34.1%), 16 clinical studies( 39.0%), 11 review studies (26.9%). 23 papers(76.7%) insisted that the effects is but 9 papers(30%) said not effective. Conclusion : The effects of probiotics in atopic dermatitis is investigated positively, however, we have to consider the methods to approach the result including the sort, amount of probiotics, how to culture, how to eat and so on.

• 한국생활과학회지
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• 제21권6호
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• pp.1059-1082
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• 2012

The purpose of this study was to analyze the trends, research methodology and findings of various researches on family resilience published in Korea over the past 13 years. A total of 93 publications related to family resilience between 1999 and June of 2012 were analyzed; 72 journal articles and 21 doctoral dissertations which had not been published in academic journals. The results are as follows; (1) There has been steady increase in the number of related researches since 1999, with a significant increase since the mid-2000s as various nontraditional families emerged and the perception of family problems began to change. (2) With regards to the methodology, the majority of the studies were empirical, using quantitative methods in both data collection and analysis. Most measurement scales employed were based on inventories developed by foreign researchers. (3) The research subjects encompass a wide range of individuals and groups from both vulnerable families and families from the general population. Additionally, some researches focused on special interest areas including program development & evaluation and scale development. Although research on family resilience has increased in quantity, there needs to be more qualitative, longitudinal and theory grounded studies on different families and individual types to better understand family resilience in depth. In addition, specific measurement scales reflecting the unique Korean family culture should be developed. Other challenges and suggestions for future research on family resilience are discussed.

• 한국보건간호학회지
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• 제29권3호
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• pp.412-425
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• 2015

Purpose: This study was conducted to understand the trend in research by analyzing previous studies related to the case management of Medicaid and to explore the direction of future research. Methods: Thirty three studies conducted from January 2003 to June 2015 were analyzed according to characteristics of researchers and subjects, research methods, measurable variables, and key words. Results: Of the studies analyzed, 69.7% were conducted on Medicaid beneficiaries, and 65.6% were conducted on the group of high risk for over medical utilization. The mainly used research design was a survey study design, which was 51.5% of them, followed by experimental (24.2%), and qualitative (12.1%) study design. Most frequently measured variables were medical utilization (62.5%), needs for case management (41.7%), and health status (25.0%). The topics most frequently studied were related to medical utilization, effect of case management, self-care, and program development in Medicaid beneficiaries and job and socio-psychological factors in case managers. Conclusion: The future direction of nursing research in Medicaid case management is to be vitalized through the expansion of the research population, and concretization and diversification of the research topics. In addition, conduct of further studies on intervention strategies and contents for improving quality of case management program is also needed.

• 한국직업건강간호학회지
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• 제14권1호
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• pp.44-55
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• 2005

Purpose: The purpose of this study was to describe the current status of work-related back pain among nurses in the U.S. Method: Literature review and website searching were conducted. Key words as 'nurse and back pain (or back injury)' were used in searching the Medline, NIOSHTIC-2and reference list of selected studies. Total studies were selected of which subjects were nurses working in the U.S., and published since 1970. Results: Though there was variation in the measurement among studies, the prevalence rate of back pain among nurses in the U.S. could be estimated about 50%. Risk factors were confirmed as the frequency of patient lifting, ward, nursing shortage, overtime, work shift, stress on physical demand, but age and work experiences showed the inconsistent relation. It has been well known that educational approach is not enough to prevent back pain. Intervention studies to apply the ergonomic approach using mechanical devices reported the effects, but the devices were less diverse than European countries or Canada. The study for lifting team was rare. Federal government developed only the guideline for nursing home that had no legal obligation. As a professional nursing organization, ANA has been trying to educate and advocate for "No lift policy" since 2003. Meanwhile, two trade unions of nurses made efforts to establish the law strengthening the responsibility of health care facilities. Conclusion: The research and policy development will be needed to prepare to rapid increase of back pain among Korean nurses.

• 대한의료기공학회지
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• 제19권1호
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• pp.116-138
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• 2019

Objective: The purpose of this study was to analyze the study on yoga for senior in Korea. Methods: As for the data collection through RISS, analysis data were collected by searching for keywords such "yoga", "senior" "elder". The analysis was classified by 1) types of thesis 2) types of study 3) number of study participants and study period 4) types of yoga 5) list of academic journals and publishers. Results: 1. A total of studies were 133, the first study on yoga for senior published 2001. Average 7 studies were published each year. The number of studies has increased since 2006 and decreased since 2010. 2. About half of the researchers related to art and physical education and sports (51.8%). And researchers related to social science published remarkable number of studies (23.3%). 3. Most of researches were experimental study. Conclusions: 1. Hatha yoga could be recommended as a suitable yoga for senior. 2. There is a growing need to develop yoga for senior in preparation for aging society. Grafting yoga on traditional Gigong practice could be a proper exercise for senior.

• Proceedings of the National Institute of Ecology of the Republic of Korea
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• 제2권4호
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• pp.247-258
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• 2021

To understand restoration and conservation projects conducted in Korea for endangered freshwater fishes and amphibians/reptiles, information about Request for Protocols-related studies on restoration, breeding, and release were collected. Trends of studies were visualized via word clouds and VOSviewer program using a text mining technique. Analysis of restoration projects for endangered freshwater fishes elucidated that most research studies conducted to date were focused on genetics and release through captive breeding that could be classified into captive breeding and habitat environments. As for research projects related to amphibians/reptiles, monitoring projects had the highest number, followed by genetic, translocation, and monitoring studies. In addition, restoration projects for amphibians/reptiles included a large number of post-capture translocation projects. Thus, many projects were confirmed by public institutions rather than by the Ministry of Environment. Network analysis revealed that it was largely classified into capture, translocation, and Kaloula borealis. Based on these results, limitations, achievements, and challenges associated with projects conducted thus far are highlighted. Research directions for future restoration and conservation of endangered freshwater fishes and amphibians/reptiles in South Korea are also suggested.

• 대한한방소아과학회지
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• 제33권1호
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• pp.34-45
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• 2019

Objectives The purpose of this study is to highlight recent gut-microbiota studies and to encourage gut-microbiota-related researches in Pediatric science of Korean Medicine. Methods We searched gut microbiota related studies and patents via the PubMed database of the US National Institutes of Health (NIH) and the PatentScope database of the UN World Intellectual Property Organization (WIPO) to see current trends of gut microbiota studies. Results All searched research and review articles in gut-microbiota studies were analyzed and presented as two charts, showing the recent trends of gut microbiota research. We summarized and discussed the significance of the selected fifty-six articles. Also, we listed reported gut-microbiota-derived small metabolites, impacting on human health and diseases. Conclusions This study emphasizes the critical roles of gut-microbiota and their-derived small metabolites in the human physiology and pathology. We know and agree that many natural compounds in Korean Medicine could be converted into small metabolites by gut microbiota in our body. Thus, it is important to encourage physicians and researchers of gut microbiota in the arena of Pediatric Korean Medicine. We believe that researchers will find a lot of unknown metabolites produced by gut microbiota from natural compounds in Korean Medicine.