• Journal of Community Nutrition
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• 제4권1호
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• pp.29-37
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• 2002

This study was designed to assess diet and health-related factors of older adults in Korea. Subjects females were 2,660 adults aged 50 and over living in Korea. Males were 847 persons and were 1813 persons. The mean weight and height for males and females were 63.8 $\pm$ 0.3kg / 164.0 $\pm$ 0.2cm and 57.0 $\pm$ 0.2kg /150.6 $\pm$ 0.1cm respectively. BMI (body mass index), body fat, and percent fat were significantly greater in females than in males. The muscle mass and body water were significantly greater in males than in females. Twenty-one percent of total subjects lived alone and 26% with spouse only. Most of the subject's self-reported income was in middle level (65%) or low level (24%). Proportion of subjects who answered 'very poor' or 'poor' on perceived health status was higher in older group. The 50-64 years old group was facing more stress than 65yr and over group. Among male subjects,38.4% were current-smokers and 22.0% were ex-smokers. But only 6.5% of female subjects were current-smokers. Males turned out to have better dietary habits-meal frequency per day, mealtime regularity, regular meal size and balanced eating-than females (p < 0.001). This study revealed that the diet and health-related factors affect nutritional status and chronic diseases of the elderly. For better management and evaluation of health status of the elderly, more effective nutritional assessment tools should be developed.

• Annals of Clinical Neurophysiology
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• 제5권2호
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• pp.171-176
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• 2003

Backgrounds and Objectives: Despite of enormous clinical and laboratory researches focused on the useful markers in status epilepticus(SE), clinically applicable methods are not yet available. Although ketogenic diet (KD) is an old method of treating epilepsies, its outstanding antiepileptic effect in some epileptic patients needs re-evaluation of this methods. This study was performed to evaluate the effect of KD on the change of nitric oxide(NO) during the SE. Methods: After the determination of critical EEG stages in the pilocarpine-induced SE model, serum NO levels were measured with Griess reaction. Open cardiac puncture was done immediately after the four different EEG stages of SE in the KD rats and regular diet (RD) rats. Cessation of SE was done with the 10~20 mg/Kg of diazepam i.p. injection in each stages of SE in KD and RD rats. Results: Pilocarpine-induced SE showed reliable EEG and behavioral patterns in all rats. Also, KD did not affect the SE induced by pilocarpine in terms of the SE induction time and SE severity. Serum NO was consistently higher in KD rats than RD rats in all SE stages. Conclusions: KD significantly increases NO during the pilocarpine-induced SE. These finding might contribute the neuroprotective effect of KD in the SE.

• 동의생리병리학회지
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• 제29권1호
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• pp.11-17
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• 2015

Overconsumption of fructose results in dyslipidemia, hypertension, which have documented as a risk of cardiovascular diseases. This experimental study was designed to investigate the beneficial effects of Rubus coreanus Miq.(RCM) in high-fructose diet-induced metabolic syndrome. Animals were divided into three groups; Control group fed regular diet and tap water, fructose groups were fed the 65% high-fructose (HF) diet with/without RCM 100 mg/kg/day for 8 weeks, respectively. Chronic treatment with RCM significantly decreased body weight, fat weight and adipocyte size. Moreover, RCM significantly prevented the development of the metabolic disturbances such as hyperlipidemia and hypertension. RCM also led to increase in high density lipoprotein level in the HF group. In addition, RCM suppressed vascular cell adhesion molecule-1 (VCAM-1) expression and significantly recovered the levels of endothelial nitric oxide synthase (eNOS) expression in aorta. These results demonstrates that RCM may be a beneficial therapeutic for metabolic syndrome through the improvement of hyperlipidemia, obesity, and hypertension.

• 대한본초학회지
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• 제30권2호
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• pp.11-18
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• 2015

Objectives : Polygoni Multiflori Radix (Jeokhasuo in Korean) is a Oriental traditional herbs widely used in East Asian countries. Overconsumption of fructose results in hypertension, dyslipidemia, obesity and impaired glucose tolerance which have documented as a risk of cardiovascular diseases. This experimental study was designed to investigate the beneficial effects of an ethanol extract from Polygoni Multiflori Radix (PMR) in high-fructose (HF) diet-induced metabolic syndrome rat model. Methods : Sprague-Dawley (SD) rats were divided into three groups; Control group, receiving regular diet and tap water, HF group, and HF + PMR group both receiving supplemented with 65% fructose (n=10), respectively. The HF + PMR group initially received HF diet with PMR (100 mg/kg/day) for 8 weeks. Results : PMR significantly prevented the metabolic disturbances such as hyperlipidemia, hypertension and impaired glucose tolerance. Chronic treatment with PMR significantly decreased body weight, fat weight and adipocyte size, suggesting a role of anti-obesity effect. PMR led to improve the hyperlipidemia through the increase in HDL cholesterol level as well as the decrease in triglyceride and LDL cholesterol level. In addition, PMR suppressed adhesion molecules and endothelin-1 (ET-1) expression in aorta resulting in the decrease of hypertension. In muscle tissue, PMR significantly recovered the HF-induced insulin resistance through increase of insulin receptor substrate-1 (IRS-1), p-$AMPK{\alpha}1/2$, and p-Akt expression. PMR improved HF-induced metabolic disorders and its action was caused by energy metabolism-mediated insulin signaling activation. Conclusions : These results demonstrate that PMR may be a beneficial therapeutic for metabolic syndrome through the improvement of hyperlipidemia, obesity, insulin resistance and hypertension.

• 한국동물학회지
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• 제16권3호
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• pp.177-184
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• 1973

成長期雄性흰쥐(Wister Institute, albino rat) 72마리를 對照群, 無處理大豆給食群 및 $100^{\circ}C$와 $120^{\circ}C$ 加熱處理大豆給食群으로 나누고 各 食餌는 蛋白質含量(14%)과 熱量400kcal/100g)을 一定하게 조절하였다. 該當食餌로 5日, 15日 및 30日 급식후 급식기간별로 腦와 大動脈의 cholesterol 含量을 관찰한 바 다음과 같은 결과를 얻었다. 1. 腦의 totaㅣ, free형 및 ester형 cholesterol은 각 급식기간별로 각 群은 對照群과 비슷한 함량을 보였다. 2. 大動脈의 total, free형 cholesterol은 5日 급식군에서 對照群보다 $100^{\circ}C$ 와 $120^{\circ}C$ 加熱處理給食群이 높은 含量을 보였으나 15日 급식군이나 30日 급식군은 모두 비슷한 함량을 보였다. 그러나 ester형 cholesterol은 각 급식기간 一定한 경향을 보이지 않았다. 이상의 결과로 보아 大豆를 無處理했을때나 $100^{\circ}C$ 와 $120^{\circ}C$ 加熱處理하여 給食시켰을 때 흰쥐의 腦와 大動脈 cholesterol 함량에 별차이가 없었음을 알수있었다.

• 한국인터넷방송통신학회논문지
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• 제23권6호
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• pp.199-208
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• 2023

국민건강보험공단에 따르면 불규칙한 식습관, 스트레스, 운동 부족 등의 요인으로 젊은 당뇨 환자가 2017년 대비 2021년에 3,564,059명으로 24.3% 증가 추세를 보였다. 모든 연령층에서 증가 중인 당뇨병은 약물치료, 규칙적인 운동, 식사요법 관리가 필요하다. 이 중 식사요법은 적절한 열량 및 균형 잡힌 3대 영양소 섭취를 필요로 하므로 매우 체계적인 관리가 필요하다. 현재 당뇨 식단 추천은 개인 정보, 건강 정보, 사회적, 문화적 측면을 고려하여 식단을 제안하지만, 건강 정보에 대한 다중 변수를 고려하지 않은 부분이 미흡하다. 이에 본 논문은 당뇨병 환자의 라이프로그 데이터를 이용한 식단 추천 시스템을 제안하여 데이터 다중 변수를 고려해 개인의 건강 상태에 따른 맞춤형 식단을 추천하고자 한다.

• 한국지역사회생활과학회지
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• 제19권2호
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• pp.191-199
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• 2008

The purpose of this study was to obtain an understanding of the effect of regular exercise on obesity indices, the psychosocial wellbeing index, dietary factors and exercise regularity among 146 healthy mothers and 146 their daughters. "Mother" subjects were divided into two groups classified as regular exercise group(REG) and none exercise group(NEG). The exercise regularity of REG's daughters(30.8%) and of NEG's daughters (2.0%) was significantly different(p<0.001). The Obesity Indices(Body Mass Index (BMI), Waist Hip Ratio(WHR) and Percentage of Ideal Body Weight(PIBW)) of NEG's daughters were significantly higher than those of REG's daughters(p<0.001). But the psychosocial wellbeing index was not significantly different between REG's daughters and NEG's daughters. Intake of total energy, protein, fat, Ca, niacin and Fe were significantly different(p<0.001) between REG's daughters and NEG's daughters. Especially, vitamin C intake of REG's daughters was significantly higher than that of NEG's daughters(p<0.001). The exercise regularity of mothers was mainly related with Obesity Indices and nutrient intake in their daughters. Therefore, it might be necessary to maintain exercise regularity to prevent obesity and diet related problems in mothers and their daughters.

• 성인간호학회지
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• 제18권5호
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• pp.790-797
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• 2006

Purpose: The purpose of this study was to investigate bone density and risk factors related to osteopenia to unmarried young adult women. Methods: The subjects consisted of 125 female college students. SPSS 12.0 program was used for the data analysis with t-test, ${\chi}^2-test$. The BMD of the calcaneus and body mass index (BMI) were measured with peripheral dual energy X-ray absorptionmetry. Other physical characteristics were measured with a scale and questionnaires. Results: The general characteristics of these people showed that the average age was 22.1 years old and that the average BMI was 20.8. The mean of BMD was normal, but 24.8% were osteopenia, 75.2% were normal. In the normal and osteopenia groups, there were significant differences in the status of the BMD according to age, height, weight, BMI, regular exercise, house chores, and the experiences of being on a diet. Conclusion: Women in their twenties had some osteoporosis risk, but they can change their BMD by doing regular exercise and by eating food to peak bone mass. For building peak bone mass, they need take exercise programs and education programs to prevent osteoporosis and follow-up care.

• Journal of Nutrition and Health
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• 제22권2호
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• pp.91-101
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• 1989

This study was performed to investigate the effects of different dietary magnesium levels on systolic blood pressure and mineral distribution in normotensive and spontaneously hypertensive rats. In experiment 1, Normotensive rats(NTR ; Sprague Dawley, Female) were given diets containing regular magnesium (0.05% Mg ; rMg), marginal magnesium (0.01% Mg ; mMg) or marginal magnesium with stress(0.01% Mg + stress ; mMg + Str). In experiment 2, spontaneously hypertensive rats (SHR ; Kyoto Wistar, Femal) were fed diets containing regular magnesium(0.05% Mg ; rMg) and high magnesium (0.2% Mg ; hMG). The following were found ; 1) NTR treated with marginal magnesium with stress showed significant increase in systolic blood pressure (SBP). Marginal magnesium diet without stress resulted in nonsignificant increase in SBP. Significant in crease of blood pressure showed in NTR treated with marginal magnesium and stress was associated with decreased magnesium and increased calcium content in femur, reticulocyte and plasma. 2) In experiment 2, magnesium supplementation to SHR showed significant attenuation of their systolic blood pressure with increasing age. The attenuation of SBP showed in SHR was associated with increased magnesium, lowered calcium content in cardiac muscle and reticulocyte and decreased plasma sodium and aldosterone level.

• Journal of Nutrition and Health
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• 제36권6호
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• pp.589-602
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• 2003

This study was designed to investigate the effects of weight reduction and changes in serum lipid composition using a commercial uncooked powdered food (UPF) diet on 27 obese hyperlipidemic women over a period of 12 weeks. We replaced the standard breakfast and dinner of each of the subjects with UPF. Their dietary intake status was evaluated by 24-hour recall method. Their body compositions were measured using a body fat analyzer. Also, we conducted hematological, clinical and lipid profile analyses of their blood. Their intake of energy, lipid and protein significantly decreased as the subjects started to take UPF, but their intake of vitamins and minerals, other than iron, increased. Due to the energy intake decrease, the subjects' weight, body fat and waist circumference significantly decreased. Among the lost weight the percentage of the body fat was high. We judged that this process of losing weight was successful in obese hyperlipidemic women. Serum HDL-cholesterol gradually increased and serum total-cholesterol, LDL-cholesterol, triglyceride levels showed gradual decreases. When obese hyperlipidemic women replaced two of three meals with UPF for 3 months, we were able to see useful changes like decreased body fat and serum lipid. Complete judgment on the usefulness of UPF may be difficult but if people take a standard meal once a day and replenish their iron by taking UPF twice a day, we assume that replacing UPF with balanced regular meal not be a problem in nutritional status. Our results show that UPF is effective in the diet therapy of obese hyperlipidemic women.