• Title/Summary/Keyword: Reducing

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The dose distribution and DVH change analysis wing to effect of the patient setup error (환자 SET-UP ERROR에 따른 선량분포와 DVH 변화 분석)

  • Kim KyoungTae;Ju SangGyu;Ahn JaeHong;Park YoungHwan
    • The Journal of Korean Society for Radiation Therapy
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    • v.16 no.2
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    • pp.81-89
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    • 2004
  • Introduction : The setup error due to the patient and the staff from radiation treatment as the reason which is important the treatment record could be decided is a possibility of effect. The SET-UP ERROR of the patient analyzes the effect of dose distribution and DVH from radiation treatment of the patient. Material & Methode : This test uses human phantom and when C-T scan doing, It rotated the Left direction of the human phantom and it made SET-UP ERROR , Standard plan and 3mm, 5mm, 7mm, 10mm, 15mm, 20mm with to distinguish, it made the C-T scan error. With the result, The SET-UP ERROR got each C-T image Using RTP equipment It used the plan which is used generally from clinical - Box plan, 3Dimension plan( identical angle 5beam plan) Also, ( CTV+1cm margin, CTV+0.5cm margin, CTV+0.3,cm margin = PTV) it distinguished the standard plan and each set-up error plan and The plan used a dose distribution and the DVH and it analyzed Result : The Box4 the plan and 3Dimension plan which it bites it got similar an dose distribution and DVH in 3mm, 5mm From rotation error and Rectilinear movement( $0\%{\sim}2\%$ ). Rotation error and rectilinear error 7mm, 10mm, 15mm, 20mm appeared effect it will go mad to a enough change in treatment ( $2\%{\sim}^11\%$ ) Conclusion : The diminishes the effect of the SET-UP ERROR must reduce move with tension of the patient Also, we are important accessory development and the supply that it reducing of reproducibility and the move

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Study on the calibration phantom and metal artifacts using virtual monochromatic images from dual energy CT (듀얼 에너지 CT의 가상 단색 영상을 이용한 영상 교정 팬텀과 금속 인공음영에 관한 연구)

  • Lee, Jun seong;Lee, Seung hoon;Park, Ju gyung;Lee, Sun young;Kim, Jin ki
    • The Journal of Korean Society for Radiation Therapy
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    • v.29 no.1
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    • pp.77-84
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    • 2017
  • Purpose: To evaluate the image quality improvement and dosimetric effects on virtual monochromatic images of a Dual Source-Dual Energy CT(DS-DECT) for radiotherapy planning. Materials and Methods: Dual energy(80/Sn 140 kVp) and single energy(120 kVp) scans were obtained with dual source CT scanner. Virtual monochromatic images were reconstructed at 40-140 keV for the catphan phantom study. The solid water-equivalent phantom for dosimetry performs an analytical calculation, which is implemented in TPS, of a 10 MV, $10{\times}10cm^2$ photon beam incident into the solid phantom with the existence of stainless steel. The dose profiles along the central axis at depths were discussed. The dosimetric consequences in computed treatment plans were evaluated based on polychromatic images at 120 kVp. Results: The magnitude of differences was large at lower monochromatic energy levels. The measurements at over 70 keV shows stable HU for polystyrene, acrylic. For CT to ED conversion curve, the shape of the curve at 120 kVp was close to that at 80 keV. 105 keV virtual monochromatic images were more successful than other energies at reducing streak artifacts, which some residual artifacts remained in the corrected image. The dose-calculation variations in radiotherapy treatment planning do not exceed ${\pm}0.7%$. Conclusion: Radiation doses with dual energy CT imaging can be lower than those with single energy CT imaging. The virtual monochromatic images were useful for the revision of CT number, which can be improved for target coverage and electron densities distribution.

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Studies on the Preparation of Improved Soysauce Kojis (메주제조개선(製造改善)에 관(關)한 연구(硏究))

  • Kim, Z.U.;Cho, M.J.;Kim, S.S.
    • Applied Biological Chemistry
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    • v.11
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    • pp.35-41
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    • 1969
  • In order to determine proper ratio of wheat to soybean of soysauce koji material for Korean people's taste, sensory evaluation for the soysauces made from soysauce kojis with various above-mentioned ratio and analysis of chemical components through the brewing period of six months were carried out. The results obtained were summarized as follows: 1. The specific gravity of all the soysauces increased gradually as the time passed and had maximum values in two months with nearly constant values thereafter. Concerning soybean/wheat-ratio, generally, the higher soybean/wheat-ratio, the lower specific gravity was observed but when this ratio was higher than 10 : 6, the gravity was on the similar levels. 2. The solid material in all the soysauces increased in the earlier stage and there were no significant differences among the treatments but soysauces without wheat had a little low content. 3. The lesser amount of wheat as raw material was, the higher contents of total nitrogen were and the contents of total nitrogen in the every ratio of raw material increased parallely as the mash ages. 4. The amino-nitrogen levels were found to have the simllar tendency to total nitroghen levels. 5. The reducing sugar content was higher in the soysauces with more-wheat and increased rapidly up to the maximum level in two months and then the higher wheat/soybean-ratio was, the slower decrease of the sugar content was observed. 6. The maximum total acidity was observed in the soysauces with 10; 4-6 (soybean/wheat-ratio) and increased similary in all the soysauces throughout the period. 7. According to the sensory evaluation, the short (2-3 months) fermented soysauces showed best taste when soybean/wheat-ratio was 10 : 8 and 10 : 6 if diluted, but in long (4-6 months) fermented soysauces it was 10 : 6 and 10 : 4 if diluted.

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On the Utilization of Inactive BHC isomers -Synthesis of 3-(2,4,5-trichlorophenyl)-1-methyl urea as a herbicide- (BHC 이성질체(異性質體)의 활용(活用)에 관(關)한 연구(硏究) -제초제(除草劑)로서 3-(2,4,5-trichlorophenyl)-1- methyl urea의 합성(合成)-)

  • Lee, Kyu-Seung;Park, Chang-Kyu
    • Applied Biological Chemistry
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    • v.22 no.2
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    • pp.109-122
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    • 1979
  • Present study was carried out to reduce residual toxicity of BHC insecticides inherent in the organochlorine pesticides. For This end, r-isomer, the most potent insecticidal component among the BHC stereoisomers, was isolated and thus fortified by means of solvent precipitation. In parallel, 3-(2,4,5-trichlorophenyl)-1-methyl urea was prepared in good yield from technical BHC via 1,2,4-trichlorobenzene, 1,2,4,-trichloronitrobenzene, and 2,4,5-trichloroaniline. In addition, certain merit of the compound which make it possible to use as a herbicide is discussed. The results are summarized as follows; 1. Recrystallizing technical BHC from methanol-water binary solvent system, r-isomer was enriched to 49.7% at 95% recovery of r-isomer. 2. By partitioning technical BHC in 85% of methanolic solution into chloroform, r-isomer was fortified to 89.6% at 90.5% recovery of r-isomer. 3. Yield of 1,2,4-trichlorobenzene from technical BHC was greatly dependent upon concentration of alkalies and to less degree on the alkalies. 4. Surfactants, in particular cationic a quartenary ammonium salt, increased yield of 1,2,4-trichlorobenzene from technical BHC by alkaline hydrolysis. 5. Conversion of 1,2,4-trichlorobenzene to 2,4,5-trichloronitrobenzene was effected almost quantitatively utilizing $HNO_3-H_2SO_4$ nitrating agent at low temperature. 6. Yield of 91.4% was observed for the synthesis of 2,4,5-trichloroaniline by reducing 2,4,5-trichloronitrobenzene in the presence of iron turning and hydrochloric acid. 7. Overall yield based on BHC of 3-(2,4,5-trichlorophenyl)-1- methyl urea was 60.8%. 8. Inhibition effects, both germination and growth, 3-(2,4,5-trichlorophenyl)-1-methyl urea on several crops were found comparable to or more potent than those of $linuron{\circledR}\;and\;diuron{\circledR}$. In addition, it was also noted that susceptibility to the prepared compound depended upon the crops as well as specific part (shoots, roots) of the plant exposed to the chemicals.

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Enhanced Anti-oxidant Activity Effects of Smilax china L. Rhizome Water Extracts Added with Its Fermented Leaf Water Extracts (발효 청미래덩굴잎 추출물의 혼합에 의한 토복령의 항산화활성 증진효과)

  • Lee, Sang-Il;Lee, Ye-Kyung;Kim, Soon-Dong;Shim, Soon-Mi;Yang, Seung Hwan;Cheng, Jinhua;Suh, Joo-Won
    • Journal of Applied Biological Chemistry
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    • v.57 no.2
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    • pp.145-152
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    • 2014
  • To evaluate the improving effects of antioxidant activity, we observed antioxidant capacities such as electron donating ability (EDA), Ferric reducing antioxidant power (FRAP), inhibitory activity of xanthine oxidase (XO) and aldehyde oxidase (AO), and sensory characteristics on mixture of Smilax china L. root water extract added with water extract of fermented S. china L. leaf by Aspergillus oryzae (FSCL). Those contents of mixture with higher ratio of FSCL were proportionally high. And OD475 of mixture with higher ratio of FSCL was almost proportionally high ($R^2=0.9850$). Antioxidant capacities of EDA and FRAP of the mixture was higher than that of non-mixture. In addition, XO inhibitory activity ($IC_{50}$) of A (1.19) was 59.80% higher than that of F (2.96), and the activity of mixture by the higher ratio of FSCL was proportionally low ($R^2=0.9490$). Taste acceptability of A was slightly higher than that of F, whereas that of C was highest. And color acceptability of 40-80% mixture was higher than those of A, F, and B. Overall acceptability of C and D was highest than those of others. Moreover, hot water extract of S. china L. leaf fermented with A. oryzae was maroon color, which looks like Puerh tea style, and mixture of S. china L. root extract added with hot water extract of S. china L. leaf was high acceptability of beverage. These results suggest that mixture of extract of S. china L. root and hot water extract of S. china L. leaf fermented with A. oryzae could improve antioxidant activities.

High-Speed Implementation and Efficient Memory Usage of Min-Entropy Estimation Algorithms in NIST SP 800-90B (NIST SP 800-90B의 최소 엔트로피 추정 알고리즘에 대한 고속 구현 및 효율적인 메모리 사용 기법)

  • Kim, Wontae;Yeom, Yongjin;Kang, Ju-Sung
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.28 no.1
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    • pp.25-39
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    • 2018
  • NIST(National Institute of Standards and Technology) has recently published SP 800-90B second draft which is the document for evaluating security of entropy source, a key element of a cryptographic random number generator(RNG), and provided a tool implemented on Python code. In SP 800-90B, the security evaluation of the entropy sources is a process of estimating min-entropy by several estimators. The process of estimating min-entropy is divided into IID track and non-IID track. In IID track, the entropy sources are estimated only from MCV estimator. In non-IID Track, the entropy sources are estimated from 10 estimators including MCV estimator. The running time of the NIST's tool in non-IID track is approximately 20 minutes and the memory usage is over 5.5 GB. For evaluation agencies that have to perform repeatedly evaluations on various samples, and developers or researchers who have to perform experiments in various environments, it may be inconvenient to estimate entropy using the tool and depending on the environment, it may be impossible to execute. In this paper, we propose high-speed implementations and an efficient memory usage technique for min-entropy estimation algorithm of SP 800-90B. Our major achievements are the three improved speed and efficient memory usage reduction methods which are the method applying advantages of C++ code for improving speed of MultiMCW estimator, the method effectively reducing the memory and improving speed of MultiMMC by rebuilding the data storage structure, and the method improving the speed of LZ78Y by rebuilding the data structure. The tool applied our proposed methods is 14 times faster and saves 13 times more memory usage than NIST's tool.

A Study on the Right Direction of Green Standard for Energy and Environmental Design(G-SEED) from the Perspective of Landscape Architecture (조경관점의 녹색건축 인증기준에 대한 방향 정립)

  • Cha, Uk Jin;Nam, Jung Chil;Yang, Geon Seok
    • Journal of the Korean Institute of Landscape Architecture
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    • v.44 no.4
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    • pp.45-56
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    • 2016
  • In this study, an analysis has been conducted on the evaluation criteria of current G-SEED(Green Standard for Energy and Environmental Design) and on the 78 buildings, certified by G-SEED, for 3 years from November, 2012 to November, 2015. Based on the results of this analysis, four issues are driven and proposed hereinafter. Issue 1 : Nowadays, the psychological proportion of landscape architecture in building is getting greater than ever so that it shows reliable reduction of carbon dioxide. Therefore, so far as the eight kinds of buildings are concerned, the evaluation items of G-SEED must include those of landscape architecture mandatorily through its enlargement. Issue 2 : It is undesirable factor that inhibits precise evaluation on landscaping area to let other areas appraise landscape architecture because it requires outstanding professionalism. So, G-SEED should not only ensure landscaping professionalism for the correct evaluation but also let landscape area participate in assessing other areas. Issue 3 : Many previous researches turned out that landscape planting technique has excellent effect on saving energy and reducing temperature of buildings. Thus, landscape planting technique of landscape area is required to be one of the evaluation items of energy sector. Issue 4 : Tree management also has to be newly included as one of the evaluation factor for the maintenance relating to the landscape architecture. G-SEED, enacted and enforced by the Green Building Creation Support Act in 2013, surely is effective system to reduce carbon dioxide in buildings. This is a special Act in its nature that is superior to Construction Law and must be observed by all means to construct buildings. Under the umbrella of this legal system, various of researches and products are contributing to creating new jobs in construction area. However, it is a well-known fact that landscape architecture area has shown less interest on this Act than that of construction area. In conclusion, it is necessary that landscape industry should conduct continuous researches on G-SEED and pay more attention to the Act enough to harvest related products and enlarge its work area.

A Study on Decreasing Effects of Ultra-fine Particles (PM2.5) by Structures in a Roadside Buffer Green - A Buffer Green in Songpa-gu, Seoul - (도로변 완충녹지의 식재구조에 따른 초미세먼지(PM2.5)농도 저감효과 연구 - 서울 송파구 완충녹지를 대상으로 -)

  • Hwang, Kwang-Il;Han, Bong-Ho;Kwark, Jeong-In;Park, Seok-Cheol
    • Journal of the Korean Institute of Landscape Architecture
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    • v.46 no.4
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    • pp.61-75
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    • 2018
  • This study aims to verify the effect of green buffers, built as urban planning facilities on the reduction of ultra-fine particulate($PM_{2.5}$) and analyze changes in ultra-fine particles by structure, green volume and planting types of wayside green buffers, thus drawing the factors that can be used when green buffers are built to reduce ultra-fine particulate based on the results. This study selected Songpa-gu, and investigated 16 sites on 5 green buffers adjacent to two of Songpa-gu's main roads, 'Yangjaedaero' and 'Songpadaero'. This study divided all the green spaces into three different types-slope type, plain type and mounding type, and analyzed the mean green volume. As a result of measuring the concentration of $PM_{2.5}$, this study found that it was $55.5{\mu}g/m^3$ on average in winter, which was a harmful level according to the integrated environmental index provided by Seoul City, saying that levels above $50{\mu}g/m^3$ may have a harmful effect on sensitive groups of people. Particularly, the concentration of $PM_{2.5}$ was $38.6{\mu}g/m^3$ on average in spring, which exceeded the mean concentration of $PM_{2.5}$ in Seoul City in 2015. The mean concentrations of $PM_{2.5}$ in every investigation spot were $46.6{\mu}g/m^3$ for sidewalks, $45.5{\mu}g/m^3$ for green spaces and $42.9{\mu}g/m^3$ for residential areas, all of which were lower than $53.2{\mu}g/m^3$ for roads, regardless of the season. The concentration of $PM_{2.5}$ for residential areas was the lowest. In the stage of confirming the effect of green buffers, this study analyzed the correlation between the green volume of vegetation and the fluctuated rate of ultra-fine particles. As a result, it was found that the green coverage rate of trees and shrubs was related to the crown volume in every investigation spot but were mutually and complexly affected by each other. Therefore, this study judged that the greater the number of layers of shrubs that are made, the more effective it is in reducing the concentration of $PM_{2.5}$. As for seasonal characteristics, this study analyzed the correlation between the concentration of $PM_{2.5}$ for residential areas in winter and the green coverage rate of each green space type. As a result, this study found that there was a negative correlation showing that the higher the shrub green coverage rate is, the lower the concentration value becomes in all the slope-type, plain-type and mounding-type green spaces. This study confirmed that the number of tree rows and the number of shrub layers have negative correlations with the fluctuated concentration rate of $PM_{2.5}$. Especially, it was judged that the shrub green volume has greater effect than any other factor, and each green space type shows a negative correlation with the shrub coverage rate in winter.

Optimization of the cryopreserved condition for utilization of GPCR frozen cells (GPCR 냉동보관 세포의 활용을 위한 냉동조건의 최적화 연구)

  • Noh, Hyojin;Lee, Sunghou
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.2
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    • pp.1200-1206
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    • 2015
  • The major target for drug discovery, G-protein coupled receptor (GPCR) is involved in many physiological activities and related to various diseases and disorders. Among experimental techniques relating to the GPCR drug discovery process, various cell-based screening methods are influenced by cell conditions used in the overall process. Recently, the utilization of frozen cells is suggested in terms of reducing data variation and cost-effectiveness. The aim of this study is to evaluate various conditions in cell freezing such as temperature conditions and storage terms. The stable cell lines for calcium sensing receptor and urotensin receptor were established followed by storing cultured cells at $-80^{\circ}C$ up to 4 weeks. To compare with cell stored at liquid nitrogen, agonist and antagonist responses were recorded based on the luminescence detection by the calcium induced photoprotein activation. Cell signals were reduced as the storage period was increased without the changes in $EC_{50}$ and $IC_{50}$ values $EC_{50}:3.46{\pm}1.36mM$, $IC_{50}:0.49{\pm}0.15{\mu}M$). In case of cells stored in liquid nitrogen, cell responses were decreased comparing to those in live cells, however changes by storage periods and significant variations of $EC_{50}/IC_{50}$ values were not detected. The decrease of cell signals in various frozen cells may be due to the increase of cell damages. From these results, the best way for a long-term cryopreservation is the use of liquid nitrogen condition, and for the purpose of short-term storage within a month, $-80^{\circ}C$ storage condition can be possible to adopt. As a conclusion, the active implementation of frozen cells may contribute to decrease variations of experimental data during the initial cell-based screening process.

EFFECT OF THE EXPONENTIAL CURING OF COMPOSITE RESIN ON THE MICROTENSILE DENTIN BOND STRENGTH OF ADHESIVES (복합레진의 exponential 중합법이 상아질접착제의 미세인장접착강도에 미치는 영향)

  • Seong, So-Rae;Seo, Duck-kyu;Lee, In-Bog;Son, Ho-Hyun;Cho, Byeong-Hoon
    • Restorative Dentistry and Endodontics
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    • v.35 no.2
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    • pp.125-133
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    • 2010
  • Objectives: Rapid polymerization of overlying composite resin causes high polymerization shrinkage stress at the adhesive layer. In order to alleviate the shrinkage stress, increasing the light intensity over the first 5 seconds was suggested as an exponential curing mode by an LED light curing unit (Elipar FreeLight2, 3M ESPE). In this study, the effectiveness of the exponential curing mode on reducing stress was evaluated with measuring microtensile bond strength of three adhesives after the overlying composite resin was polymerized with either continuous or exponential curing mode. Methods: Scotchbond Multipurpose Plus (MP, 3M ESPE), Single Bond 2 (SB, 3M ESPE), and Adper Prompt (AP, 3M ESPE) were applied onto the flat occlusal dentin of extracted human molar. The overlying hybrid composite (Denfil, Vericom, Korea) was cured under one of two exposing modes of the curing unit. At 48h from bonding, microtensile bond strength was measured at a crosshead speed of 1.0 mm/min. The fractured surfaces were observed under FE-SEM. Results: There was no statistically significant difference in the microtensile bond strengths of each adhesive between curing methods (Two-way ANOVA, p > 0.05). The microtensile bond strengths of MP and SB were significantly higher than that of AP (p < 0.05). Mixed failures were observed in most of the fractured surfaces, and differences in the failure mode were not observed among groups. Conclusion: The exponential curing method had no beneficial effect on the microtensile dentin bond strengths of three adhesives compared to continuous curing method.