• Title/Summary/Keyword: Reduced-order-model

Search Result 1,126, Processing Time 0.028 seconds

Surgical Results of 80 Patients with Growth Hormone-Producing Pituitary Adenomas : Analysis of Outcome and Prognostic Factors (성장호르몬분비 뇌하수체 선종 80예의 수술성적 및 예후 인자의 분석)

  • Kim, Jeong Eun;Jung, Hee-Won;Gwak, Ho-Shin;Paek, Sun Ha;Kim, Dong Gyu;Choi, Kil Soo
    • Journal of Korean Neurosurgical Society
    • /
    • v.29 no.6
    • /
    • pp.754-762
    • /
    • 2000
  • Objectives : The surgical results of 80 patients with growth hormone(GH)-producing pituitary adenoma were analyzed retrospectively to evaluate the clinical manifestations and to determine which preoperative factors significantly influenced the surgical outcome. Patients and Methods : The patients consisted of 39 men and 41 women and the age of patients at the time of initial operation ranged from 17 to 67 years(mean age, 40.5 years) Between January 1990 and June 1996, 77 patients underwent transsphenoidal surgery and 3 patients underwent craniotomy for GH-producing pituitary adenoma at our institution. Preoperative administration of octreotide was performed in 18 patients. Surgical control was defined as a postoperative serum basal level of GH less than 5ng/ml. A logistic regression model was used for univariate and multivariate analysis. Probability value of less than 0.05 was considered as statistically significant. Results : The most common presenting symptom was acromegaly, followed by headache, visual disturbance, and fatigability. Visual symptoms were present in 39% of the patients. Diabetes mellitus was associated in 24 patients and hypertension in 12. Preoperative mean basal level of GH was 93.2ng/ml(range 72-500ng/ml) which was closely related with tumor size(p<0.05). Grade II by Hardy's classification was the most common radiological type. Preoperative octreotide treatment significantly reduced the level of GH(p<0.05), but not enough to induce endocrinological remission. One patient died of cerebral infarction after craniotomy. The most common surgical complication was transient diabetes insipidus. The symptom of the earliest improvement after surgery was paresthesia and tightness of the hand and foot, followed by headache and easy fatigability. The preoperative visual symptom was improved in all patients. The patients who had hypertension or DM experienced alleviated symptoms in 67% and 92%, respectively. The overall rate of endocrinological remission was 44%. By multivariate logistic regression analysis, the size of tumor, extrasellar extension, and extent of removal were significant prognostic factors for endocrinologial remission. Conclusion : Early detection of a small tumor without extrasellar extension followed by a complete resection is highly recommended in order to achieve endocrinological cure of GH-producing pituitary adenomas.

  • PDF

Characteristic of Buckling and Ultimate Strength of the Perforated Stiffened Plate (유공보강판의 좌굴 및 극한강도 특성에 관한 연구)

  • Park Joo-Shin;Ko Jae-Yong;Oh Kyoung-Gun
    • Journal of Navigation and Port Research
    • /
    • v.30 no.6 s.112
    • /
    • pp.439-446
    • /
    • 2006
  • In ship structures many of the structural plates have cutouts, for example, at inner bottom structure, girder, upper deck hatch, floor and dia-frame etc. In the case where a plate has a cutout it experiences reduced buckling and ultimate strength and at the same time the in-plane stress under compressive load produced by hull girder bending will be redistributed In general, actual ship structure adopted reinforcement of stiffener around the cutout in order to preventing from buckling so it need to examine a buckling and ultimate strength behaviour considering a cutout because In many ship yards used class rule for calculating buckling strength but it is difficult to evaluate perforate stiffened plate with random size. In the present paper, we investigated several kinds of perforated stiffened model from actual ship and then was performed finite element series analysis varying the cutout ratio, web height, thickness and type of cross-section using commercial FEA program(ANSYS) under compressive load.

Forecasting the Grain Volumes in Incheon Port Using System Dynamics (System Dynamics를 이용한 인천항 양곡화물 물동량 예측에 관한 연구)

  • Park, Sung-Il;Jung, Hyun-Jae;Yeo, Gi-Tae
    • Journal of Navigation and Port Research
    • /
    • v.36 no.6
    • /
    • pp.521-526
    • /
    • 2012
  • More efficient and effective volume management of trade cargo is recently requested due to FTA with foreign country. Above all, the grain is the main cargo needed in Korean food life and was appointed as the core trade cargo during FTA. This study is aimed to forecast future demands of grain volumes which are handled at Incheon port because most of the grain volumes are traded at Incheon port in Korea. System Dynamics (SD) was used for forecasting as the methodology. Also, population, yearly grain consumption per a man, GDP, GRDP, exchange rate, and BDI were used as the factors that influence grain volumes. Simulation duration was from 2000 to 2020 and real data was used from 2000 to 2007. According to the simulation, 2020's grain volumes at Incheon port were forecasted to be about 2 million tons and grain volumes handled at Incheon port were continuously reduced. In order to measure accuracy of the simulation, this study implemented MAPE analysis. And after the implementation, the simulation was decided as a much more accurate model because MAPE value was calculated to be 6.3%. This study respectively examined factors using the sensitivity analysis. As a result, in terms of the effects on grain volume in Incheon Port, the population factor is most significant and exchange rate factor is the least.

Improvement of a Verified Secure Key Distribution Protocol Between RFID and Readers (RFID와 리더간의 안전성이 검증된 키 분배 프로토콜의 개선)

  • Bae, Woo-Sik;Lee, Jong-Yun
    • The KIPS Transactions:PartC
    • /
    • v.18C no.5
    • /
    • pp.331-338
    • /
    • 2011
  • The RFID system includes a section of wireless communication between the readers and the tags. Because of its vulnerability in terms of security, this part is always targeted by attackers and causes various security problems including the leakage of secret and the invasion of privacy. In response to these problems, various protocols have been proposed, but because many of them have been hardly implementable they have been limited to theoretical description and theorem proving without the accurate verification of their safety. Thus, this study tested whether the protocol proposed by Kenji et al. satisfies security requirements, and identified its vulnerabilities such as the exposure of IDs and messages. In addition, we proposed an improved RFID security protocol that reduced the number of public keys and random numbers. As one of its main characteristics, the proposed protocol was designed to avoid unnecessary calculations and to remove vulnerabilities in terms of security. In order to develop and verify a safe protocol, we tested the protocol using Casper and FDR(Failure Divergence Refinements) and confirmed that the proposed protocol is safe in terms of security. Furthermore, the academic contributions of this study are summarized as follows. First, this study tested the safety of a security protocol through model checking, going beyond theorem proving. Second, this study suggested a more effective method for protocol development through verification using FDR.

Gravimetric and magnetic studies in an Yangsan fault area near Angang (안강부근 양산단층 지역에서의 중력 및 지자기 연구)

  • Kim, Gi Yeong;Lee, Gwang Ja
    • Journal of the Korean Geophysical Society
    • /
    • v.1 no.1
    • /
    • pp.31-40
    • /
    • 1998
  • Gravimetric and magnetic surveys were conducted in order to reveal near-surface structures such as basements, faults, and fracture zones in an area near Angang, where the Yangsan fault is believed to pass through. Along two lines approximately perpendicular to the strike of the major fault, gravity and magnetic data were measured at 67 stations with a 15 m interval and at 296 stations with a 3 m interval, respectively. Average depth to the magnetic basement is estimated using the spectral analysis method to be 8.5 and 10.0 m along lines located to the east and the west of the Hyeongsan river, respectively. Average value of reduced gravity on the east line is higher than that on the west by the amount of 1.71 mGal, which indicates that the basement rocks are more severely fractured in the western part. Forward gravity modeling along the east line indicates that a fracture zone extends westward from a fault located 210 m west of the eastern end. Density and depth to the bottom of the fracture zone are estimated to be 2.44 g/cm3 and 70 m, respectively. The gravity model study also indicates presence of a small graben, 190 m wide and 3.5 m deep on an average, on the basement surface. The earth surface above the graben is approximately 44 cm lower than the nearby surface. This indicates that the graben might have been formed by recent fault movements.

  • PDF

Design of Sliding Mode Fuzzy Controller for Vibration Reduction of Large Structures (대형구조물의 진동 감소를 위한 슬라이딩 모드 퍼지 제어기의 설계)

  • 윤정방;김상범
    • Journal of the Earthquake Engineering Society of Korea
    • /
    • v.3 no.3
    • /
    • pp.63-74
    • /
    • 1999
  • A sliding mode fuzzy control (SMFC) algorithm is presented for vibration of large structures. Rule-base of the fuzzy inference engine is constructed based on the sliding mode control, which is one of the nonlinear control algorithms. Fuzziness of the controller makes the control system robust against the uncertainties in the system parameters and the input excitation. Non-linearity of the control rule makes the controller more effective than linear controllers. Design procedure based on the present fuzzy control is more convenient than those of the conventional algorithms based on complex mathematical analysis, such as linear quadratic regulator and sliding mode control(SMC). Robustness of presented controller is illustrated by examining the loop transfer function. For verification of the present algorithm, a numerical study is carried out on the benchmark problem initiated by the ASCE Committee on Structural Control. To achieve a high level of realism, various aspects are considered such as actuator-structure interaction, modeling error, sensor noise, actuator time delay, precision of the A/D and D/A converters, magnitude of control force, and order of control model. Performance of the SMFC is examined in comparison with those of other control algorithms such as $H_{mixed 2/{\infty}}$ optimal polynomial control, neural networks control, and SMC, which were reported by other researchers. The results indicate that the present SMFC is an efficient and attractive control method, since the vibration responses of the structure can be reduced very effectively and the design procedure is simple and convenient.

  • PDF

Development of Korean Cultural Competency Scale for Human Service Workers (다문화 사회복지 실무자의 문화적 역량 척도개발 및 타당화)

  • Nho, Choong-Rai;Kim, Jeong-Hwa
    • Korean Journal of Social Welfare
    • /
    • v.63 no.2
    • /
    • pp.207-231
    • /
    • 2011
  • This study aims to identify constructs of cultural competency specifically relevant to the Korean society and to test its reliability and validity among human service workers. For the purpose of the study, authors conducted focus group interviews and conferences with human service workers to draw the concept of cultural competency. Further, this study conducted to two separate pilot tests with 20 social workers with practice experiences in order to clarify descriptions and relevance of scale items. Based on the literature review on the concept of cultural competency and analysis of focus group interviews, 40 items were initially constructed and then were reduced to a 32-item scale after two separate pilot studies. Meantime, suggestions made by an advisory group were also reflected in the scale development process. Finally, one hundred ninety four workers in social service agencies were recruited to evaluate the relevance of the scale items in a 5 point Likert scale. Through exploratory and confirmatory factor analysis, 4 main factors were identified: 1) competency to use culturally relevant skills, 2) cultural awareness and sensitivity, 3) cultural knowledge, and 4) efforts to overcome cultural differences. These factors were consistent with sub-concepts of cultural competency in other studies. Confirmatory factor analysis also showed that the model fitness was at the high level and convergent analysis with the similar scale also showed high correlations. Internal consistency also remained at a high level. Based on the results, implication for social work practice and education were discussed.

  • PDF

Flow Resistance of Model Cage Net (모형 우리 그물의 유수저항)

  • KIM Tae-Ho;KIM Dae-An;RYU Cheong-Ro;KIM Jae-O;JEONG Eui-Cheol
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.33 no.6
    • /
    • pp.514-519
    • /
    • 2000
  • In order to develop the method for the calculation of flow resistance acting on cage net, the relation between the velocity reduction factor and $S_n/S$, the ratio of total area of netting projected to the perpendicular to the water flow $S_n$ to wall area of netting S, was derived based on the numerical and experimental analysis of the wake flow through a netting twine simplified by a cylinder and a netting panel. The velocity was reduced in accordance with the velocity reduction factor when the flow passed the netting panel upstream of a cage net. The proposed method for the calculation of fluid force acting on a square cage net was based upon the assumption that it could be divided into four side panels and one bottom panel. It was proved that the force could be calculated by the sum of the drag forces acting on the individual netting panels.

  • PDF

Natural Substance MS-10 Improves Women's Health via Regulation of Estrogen Receptor (천연소재 MS-10의 에스트로겐 수용체 조절을 통한 여성건강 증진)

  • Noh, Yoo-Hun;Lee, Ji Won;Park, Jiae;Lee, Sang Hyung;Lee, Jun Young;Kim, Sung-Su;Park, Kwang-Kyun;Kim, Tae Jin;Myung, Soon-Chul;Jeong, Yoonhwa
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.45 no.6
    • /
    • pp.903-910
    • /
    • 2016
  • In this study, the expression level of estrogen receptor in an ovariectomized rat model was effectively enhanced by MS-10, Cirsium japonicum and Thymus vulgaris extract complex, in a reversible manner. MS-10 plays a positive role in enhancing estrogen activity at low concentrations, leading to improved women's health. In order to determine whether or not MS-10 improves menopausal symptoms clinically, a randomized, double-blinded, and placebo-controlled clinical study was carried out on 62 middle-aged women treated with 500 mg of MS-10 or placebo daily for 12 weeks. Clinical menopausal symptoms were evaluated by Kupperman's index (KI) detecting various menopausal symptoms, including hot flushes, parenthesis, insomnia, nervousness, melancholia, dizziness, fatigue, rheumatic pain, palpitations, formication, and headaches. Total KI score decreased significantly by about 18% upon ingestion of MS-10. Colpoxerosis, a main symptom of menopause, was significantly reduced by about 21% upon ingestion of MS-10 in contrast to placebo. In addition, reduction of insulin-like growth factor-1 with age was improved by over 10% upon ingestion of MS-10, whereas there were no significant difference with placebo. No side effects appeared after treatment with MS-10. Thus, MS-10 can be suggested as a plausible natural substance for improving women's health.

An enhancement of GloSea5 ensemble weather forecast based on ANFIS (ANFIS를 활용한 GloSea5 앙상블 기상전망기법 개선)

  • Moon, Geon-Ho;Kim, Seon-Ho;Bae, Deg-Hyo
    • Journal of Korea Water Resources Association
    • /
    • v.51 no.11
    • /
    • pp.1031-1041
    • /
    • 2018
  • ANFIS-based methodology for improving GloSea5 ensemble weather forecast is developed and evaluated in this study. The proposed method consists of two steps: pre & post processing. For ensemble prediction of GloSea5, weights are assigned to the ensemble members based on Optimal Weighting Method (OWM) in the pre-processing. Then, the bias of the results of pre-processed is corrected based on Model Output Statistics (MOS) method in the post-processing. The watershed of the Chungju multi-purpose dam in South Korea is selected as a study area. The results of evaluation indicated that the pre-processing step (CASE1), the post-processing step (CASE2), pre & post processing step (CASE3) results were significantly improved than the original GloSea5 bias correction (BC_GS5). Correction performance is better the order of CASE3, CASE1, CASE2. Also, the accuracy of pre-processing was improved during the season with high variability of precipitation. The post-processing step reduced the error that could not be smoothed by pre-processing step. It could be concluded that this methodology improved the ability of GloSea5 ensemble weather forecast by using ANFIS, especially, for the summer season with high variability of precipitation when applied both pre- and post-processing steps.