• 동의생리병리학회지
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• 제33권4호
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• pp.239-248
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• 2019

There are no published data on Gyeongokgo (GOK) safety or efficacy despite being commonly use. The Gyeongokgo (GOK) is commonly used in traditional Korean medicine to promote a health qi and blood, but their objective data was not sufficient in clinical field. To investigate the safety and efficacy of GOK with hematologic and serologic testing and the change of the quality of life in healthy individuals. Randomized, subject-assessor-blind, placebo-controlled, single-center pilot study Participants and Interventions 29 healthy volunteer subjects were randomly placed into the GOK group (n = 20) or placebo control group (n = 9) and instructed to take one treatment packet (GOK or placebo) twice daily for 4 weeks. Subjects were assessed using the Fatigue Severity Scale (FSS) and Short Form 36 Health Survey (SF-36) and underwent hematologic and serologic tests and body composition analysis. The FSS total score (p = 0.093) and SF-36 general health index (p = 0.002) were improved following treatment in the GOK group. Post-treatment thyroid-stimulating hormone levels were increased in the GOK group compared with pre-treatment levels (p = 0.0042). C-reactive protein levels decreased (p = 0.0256) in the GOK group compared with that the placebo group. In time-series tests, GOK did not affect post-prandial serum triglycerides, glucose, insulin, or C-peptide levels. Notably, elevations in serum fasting triglycerides at 2- (p = 0.0333) and 4-hours (p = 0.0414) post-prandial were lower than those in the placebo group. GOK reduced fatigue levels and did not significantly affect laboratory test results performed to measure safety, serum glucose, and lipid profiles. Post-meal triglyceride levels were effectively reduced with treatment.

• Journal of Medicine and Life Science
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• 제19권1호
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• pp.20-25
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• 2022

This study aimed to examine the changes in the Numerical Rating Scale (NRS), Oswestry Disability Index (ODI), and Roland Morris Disability Questionnaire (RMDQ) scores before and after epidural steroid injection (ESI) in patients with lower back pain, and the correlation between the three scales in patients with reduced scores on these scales. Patients completed the NRS, ODI, and RMDQ before and after receiving ESI. A paired t-test was performed to compare the mean scores obtained before and after ESI. The correlations between the scores were estimated by calculating the difference between the baseline and follow-up scores. Of the 49 patients, 37 completed both questionnaire assessments. Among them, 26 patients (70%) presented a post-ESI decrease in scores obtained on all three scales. The NRS score decreased from 6.81±1.91 points at baseline to 3.66±2.22 points at follow-up (P<0.0001); similarly, the ODI score decreased from 41.65±14.76 to 30.38±16.16 points (P=0.0025); and the RMDQ score decreased from 11.11±5.68 to 7.64±5.74 points (P=0.011). Of the 37 patients who completed the two questionnaires, 26 had reduced NRS, ODI, and RMDQ scores. The intraclass correlation coefficients between the NRS and ODI, NRS and RMDQ, and ODI and RMDQ scores were 0.7943, 0.6615, and 0.7182, respectively. The concordance correlation coefficients between the NRS and ODI, NRS and RMDQ, and ODI and RMDQ scores were 0.6020, 0.4938, and 0.5202, respectively. Among the measurements, the correlation between the NRS and ODI scores was the highest, and a moderate correlation was found between the scores obtained using the other instruments.

• 한국지반공학회논문집
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• 제23권6호
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• pp.5-21
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• 2007

보강토 옹벽은 기존 콘크리트 옹벽에 비하여 많은 장점을 지니고 있으나 장기적으로 지속하중 혹은 반복하중 등에 의한 잔류변형의 우려로 영구 구조물로서의 적극적인 적용에 장애가 되고 있다. 이 문제를 해결하기 위해서는 보강토 구조물의 시간 의존적 잔류변형 메카니즘의 규명과 아울러 잔류변형을 예측하고 제어하는 기술이 확보되어야 한다. 본 연구에서는 이러한 연구의 필요성에 근거하여 보강토 옹벽에 발생할 수 있는 장기변형 특성 고찰에 주안점을 두고 지오그리드와 표준사로 뒤채움된 모형 보강토 옹벽에 대한 지속하중 혹은 반복하중 등 다양한 하중이력에 대한 보강토 구조물의 장기변형 특성 메카니즘을 축소모형실험을 통해 고찰하였다. 그 결과 보강토 옹벽의 시간의존적 변형은 작용하는 하중특성 뿐만 아니라 뒤채움흙 및 보강재의 역학적 특성에도 많은 영향을 받는 것으로 나타났으며, 선행하중을 작용함으로써 시간 의존적 잔류변형을 제어할 수 있는 것으로 파악되었다.

• 한국지반공학회논문집
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• 제34권12호
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• pp.7-17
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• 2018

PHC-W흙막이벽체와 결합된 지하증설벽체의 테스트베드를 구축중에 있다. 지하증설벽체의 제원을 결정하기 위하여 실대형 지하증설벽체의 핵심 부재를 제작하여 휨강도실험 및 전단강도실험을 실시하였다. 원형 PHC말뚝의 단면 형상을 개량하여 개발된 PHC-W 흙막이벽체를 건축물 지하벽체로 활용하기 위하여 합성증설벽체와 비합성증설벽체를 제작하여 휨강도 및 전단강도 실험을 수행하였다. 합성증설벽체와 비합성증설벽체에서 휨모멘트 강도 실험값 및 전단강도 실험값이 유사한 수준으로 나타났으므로 합성증설벽체 대신에 시공이 간편하고 비용이 절감될 수 있는 비합성증설벽체를 적용할 수 있다는 것을 확인하였다. 실대형 모형 증설벽체는 두께 200mm로 제작되었는데, PHC-W 흙막이벽체와 결합된 지하증설벽체의 경우 동등 지하실 규모의 통상적인 지하벽체보다 두께를 100~200mm 정도 절감할 수 있는 것을 확인할 수 있었다.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2005년도 제24회 춘계학술대회논문집
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• pp.16-19
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• 2005

본 연구에서는 우주발사체에 적용할 킥 모터에 대한 기초설계 및 분석을 수행하였다. KM은 KSLV-I의 2단으로서 개발된다. 고체모터는 HTPB계열의 복합제 추진제, 복합재 모터 케이스 및 잠입형 노즐을 갖고 있으며 체계요구조건에 맞도록 개발하기 위해 실물형 추진기관의 $50\%$크기의 축소형 모터를 선행 개발, 시험하였다.

• Tribology and Lubricants
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• 제25권2호
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• pp.86-95
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• 2009

Adhesion tests were carried out in order to investigate the effect of temperature on the adhesion behavior between a PMMA film and a fused silica lens in the micro scale. For the tests, a microtribometer system was specially designed and constructed. The pull-off forces on the PMMA film were measured under atmospheric condition as the temperature of the PMMA film was increased from 300 K to 443 K and decreased to 300 K. The contact area between the PMMA film and the lens was observed during the test. The adhesion behavior was changed with the change of the PMMA surface state as the temperature increased. In glassy state below 363 K, the pull-off force did not change with the increase of temperature. In rubbery state from 383 K to 413 K, the pull-off force increased greatly as the temperature increased. In addition, the area of contact was enlarged. In viscous state above 423 K, the fingering instability was observed in the area of contact when the PMMA film contacted with the lens. It was also found that the adhesion behavior can be varied with the thermal history of the PMMA film. The residual solvent in the PMMA film could emerge to the PMMA surface due to the heating and reduced the pull-off force.

• The Journal of Korean Physical Therapy
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• 제19권1호
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• pp.1-9
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• 2007

Purpose: Stenosing tenosynovitis is a stenosing condition of the sheath of the abductor pollicis longus and extensor pollicis brevis tendons at the radial styloid process. The purpose of this study was to investigate the effects of kinesio taping on the pain and grip power in patients with de Quervain's disease. Method: 20 female with de Quervain's disease was recruited. This procedure was performed with or without taping procedure. Pain levels were assessed using a visual analogue scale, and spherical and pinch grip powers were assessed using a dynamometer. Results: 1. Resting pain, Finkelstein test pain, and Tenderness using VAS scale was showed significantly reduced after taping application(p<0.01). 2. Spherical grip power using dynamometer was showed significantly increased after taping application(p<0.01). 3. Pinch grip power using dynamometer was showed significantly increased after taping application(p<0.01). Conclusion: So we thought that kinesio taping therapy had effects on the pain release and grip power increasing to the small or local muscle groups and joints.

• 대한암한의학회지
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• 제22권2호
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• pp.13-24
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• 2017

Objectives: The purpose of this study is to report the effect of Korean Herbal Medicine (KHM) on a Renal Cell Carcinoma with multiple liver metastases patient. Methods: One renal cell carcinoma with multiple liver metastases patient was treated by KHM in conjunction with targeted anticancer agent (Afinitor). The effect of KHM was measured by scanning with Computed Tomography (CT), Blood Test, Visual Analogue Scale (VAS) and Eastern Cooperative Oncology Group scale. Results: Multiple hepatic tumors were reduced after the treatment during 5 months (Partial Remission, PR). As treatment was performed, complications induced by targeted anticancer agent (Afinitor) were alleviated. Conclusions: This case provides us a possibility that Korean Herbal Medicine offers potential benefits for renal cell carcinoma with multiple liver metastases patient.

• 가정∙방문간호학회지
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• 제17권2호
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• pp.127-134
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• 2010

Purpose: This study was done to identify the effects of stress management program on perceived stress, geriatric depression, and somatic symptom in elderly Korean subjects. Methods: A pre-post test design with a nonequivalent control group was used. Fifty elderly Korean subjects with mild depression were recruited from the registerants at four public senior citizen centers within S-gu in Seoul. They were randomly allotted to the experimental group(n=25) and control group(n=25). The intervention was performed for one hour each week at each center for 5 weeks. The effects were measured by Perceived Stress Scale, Geriatric Depression Scale-Korean, and Patient Health Questionnaire-15. Results: Perceived stress and depression were significantly reduced in experimental group. The somatic symptom was not significantly different in the experimental group. Conclusion: The stress management program may have merit in improving mental health of elderly Koreans, although this conclusion is equivocal pending further well-controlled studies that include mediation techniques such as conversion therapy and health gymnastics.

• 설비공학논문집
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• 제21권1호
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• pp.41-48
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• 2009

The present study has been performed to investigate the thermal characteristics of under-ventilated compartment fire which is a typical fire condition in structures. A series of fire experiments was conducted to characterize the thermally driven flow in a 2/5 scale ISO 9705 fire compartment. Three different fuels were used in this test series, methane gas, heptane pool, and polystyrene pellets fire. In order to measure accurate temperature, double shield aspirated thermocouples reducing the effect of radiative energy exchange on temperature measurement were used in addition to bare bead thermocouples. The upper layer temperature for well ventilated fire was increased with increasing heat release rate, but it was slightly decreased for under-ventilated fire. The measured temperatures in the upper layer at the front sampling location were higher than at the rear. Thermal characteristics through the doorway were also analysed for a wide range of heat release rates. This study provides a comprehensive and quantitative assessment of fire behavior for under-ventilation condition of fire.