The first morphogenetic event of preimplantation development, compaction, was required efficient production of porcine embryos in vitro. Compaction of the porcine embryo, which takes place at post 4-cell stage, is dependent upon the adhesion molecule E-cadherin. The E-cadherin through ${\beta}$-catenin contributes to stable cell-cell adhesion. Rho-associated kinase (ROCK) signaling was found to support the integrity of E-cadherin based cell contacts. In this study, we traced the effects of ROCK-1 on early embryonic development and structural integrity of blastocysts in pigs. Then, in order to gain new insights into the process of compaction, we also examined whether ROCK-1 signaling is involved in the regulation of the compaction mediated by E-cadherin of cellular adhesion molecules. As a result, real-time RT-PCR analysis showed that the expression of ROCK-1 mRNA was presented throughout porcine preimplantation stages, but not expressed as consistent levels. Thus, we investigated the blastocyst formation of porcine embryos treated with LPA and Y27632. Blastocysts formation and their qualities in LPA treated group increased significantly compared to those in the Y27632-treated group (p < 0.05). Then, to determine whether ROCK-1 associates embryonic compaction, we explored the effect of activator and/or inhibitor of ROCK-1 on compaction of embryos in pigs. The rate of compacted morula in LPA treated group was increased compared to that in the Y27632-treated group (39.7 vs 12.0%). Furthermore, we investigated the localization and expression pattern of E-cadherin at 4-cell stage porcine embryos in both LPA- and Y27632-treated groups by immunocytochemical analysis and Western blot analysis. The expression of E-cadherin was increased in LPA-treated group compared to that in the Y27632-treated group. The localization of E-cadherin in LPA-treated group was enriched in part of blastomere contacts compared to that Y27632-treated group. ROCK-1 as a crucial mediator of embryo compaction may plays an important role in regulating compaction through E-cadherin of the cell adhesion during the porcine preimplantation embryo. We concluded that ROCK-1 gene may affect the developmental potential of porcine blastocysts through regulating embryonic compaction.
Providing personalized services customized to users' needs and preferences becomes highlighted as a key area of user-context computing. It is essential for context-aware technology to be developed more intelligent and meaningful services by being widely applied to a variety of sectors and domains. SDO (Standard Development Organization) such as MPEG and W3C has been actively developed to be standardized services and to improve context-awareness services. Yet current standards related to context-aware technology, such as MPEG-7, MPEG-21, MPEG-V, and emotionML, are not capable enough to support various systems and diverse services. Against this backdrop, the MPEG User Description, referred to also as MPEG-UD Standard, is to ensure interoperability among recommendation services, which take into account user's context when generating recommendations to users. In this light, we introduce standards related to the user context and propose the structure for RD-Engine and the Remote Responsive User Interface(RRUI) system in reference to MPEG-UD. This system collects unit resources matching specific condition according to the user's contexts described by MPEG-UD. In so doing, it improves adaptive user interface considering device features in real-time. By automatically generating adaptive user interfaces tailored to an individual's contexts, the proposed system aims to achieve high-quality user experience for a complex service.
Kim Bo Youn;Jang Kyung Ho;Koo Sang Ok;Jung Soon Ki
Journal of KIISE:Computer Systems and Theory
/
v.33
no.1_2
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pp.137-146
/
2006
Traditional live video streaming systems support the limited field of view (FOV) of image to the remote users. A server system based on the pan/tilt camera provides a user with wide view by changing the view direction of the camera mechanically. But, when many clients try to access to the server, this system can not offer their own view to every user simultaneously, and moreover it has the delay by camera motion. In order to offer wide views to several users, we propose new streaming system using the panorama image that has wide view. Our system is a kind of implementation of software pan/tilt camera. The server acquires panorama video and sends a part of the video to clients. Then, each client can control their own view. We need the effective way to reduce the average transmission data size and server burden to the compression because generally the full size of panorama video is too big to be served by the real-time streaming. To solve this problem, we propose an strip-based video compression and adaptive transmission of the compressed multiple strip videos. Experimental results show that our system can be adapted quickly to the change of view and the number of clients. Furthermore, proposed method effectively reduce the transmission data.
Park, Se-Hwan;Ahn, Seong-Kyu;Chang, Hong Lae;Han, Bo Young;Kim, Bong Young;Kim, Dongseon;Kim, Ho-Dong;Lee, Chaehun;Oh, Jong-Myeong;Seo, Hee;Shin, Hee-Sung;Won, Byung-Hee;Ku, Jeong-Hoe
Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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v.15
no.3
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pp.191-197
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2017
The Korea Atomic Energy Research Institute (KAERI) has developed a safeguards technology for pyroprocessing based on the Safeguards-By-Design (SBD) concept. KAERI took part in a Member-State Support Program (MSSP) to establish a pyroprocessing safeguards approach. A Reference Engineering-scale Pyroprocessing Facility (REPF) concept was designed on which KAERI developed its safeguards system. Recently the REPF is being upgraded to the REPF+, a scaled-up facility. For assessment of the nuclear-material accountancy (NMA) system, KAERI has developed a simulation program named Pyroprocessing Material Flow and MUF Uncertainty Simulation (PYMUS). The PYMUS is currently being upgraded to include a Near-Real-Time Accountancy (NRTA) statistical analysis function. The Advanced Spent Fuel Conditioning Process Safeguards Neutron Counter (ASNC) has been updated as Non-Destructive Assay (NDA) equipment for input-material accountancy, and a Hybrid Induced-fission-based Pu-Accounting Instrument (HIPAI) has been developed for the NMA of uranium/transuranic (U/TRU) ingots. Currently, performance testing of Compton-suppressed Gamma-ray measurement, Laser-Induced Breakdown Spectroscopy (LIBS), and homogenization sampling are underway. These efforts will provide an essential basis for the realization of an advanced nuclear-fuel cycle in the ROK.
At the spots of enterprises experiencing rapid environmental changes, necessity for ceaseless managemental innovation is raised. We can't deny that management quality is also a part of such managemental innovation. Introduction of management quality by an organization is different from introduction of other individual innovative techniques. Management quality is not one time project but complete historical change program to be pursued continuously. Furthermore, it must be understood as a strategic 'Quality Journey' looking for far future of an organization. Malcolm Baldrige Model has been increasingly used in Korea as a global standard for management quality. The model, however, has shown a number of limitations in application due to nonsystematic elements in the implementation process. The deployment process of the model should be detailed through a real world case study. In this research, we proposed a quality evaluation standard model which is suitable for the Korean public enterprise based on the Malcolm Baldrige Non-profit Criteria, and examined the model. A 7-Point Likert Scale was used based on the seven categories within the 2007 Malcolm Baldrige Non-profit Criteria: Leadership, Strategic Planning, Customer and Market Focus, Management Analysis and Knowledge Management, Workforce Focus, Process Management, and Results. Furthermore, we analysed the validity and causal relationship among the factors within the model. Through the above case study, following common factors for successful Malcolm Baldrige Model have been derived. The following is a summary of the results of this study. First, for Malcolm Baldrige Model management, needs powerful support Leadership. Second, for Malcolm Baldrige Model management, needs systematic Strategic Planning. Third, for Malcolm Baldrige Model management, needs the continuous Customer and Market Focus. Fourth, for Malcolm Baldrige Model management, needs systematic Measurement Analysis and Knowledge Management. Five, for Malcolm Baldrige Model management, needs systematic Workforce Focus. Six, for Malcolm Baldrige Model management, needs systematic Process Management. The finding are surely necessary factors to arrange the human resource management for upgraded management quality, those factors help to explain why all enterprises consider human resource as the strategic view.
Journal of the Korean Association of Geographic Information Studies
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v.15
no.1
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pp.159-171
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2012
This study has developed a technology for river basin including the management of the data related with riverbed and the analysis of the riverbed maintenance based on the high-resolution imagery data and LiDAR (Light Detection and Raging) in order to enhance the utilization of river management by using RIMGIS(River Information Management GIS) and to acquire the advanced operation for river management. Using the detailed river topographical map specially designed in the form of LiDAR or high-resolution images, riverbed data and river bank channel information that are dynamically changed were informationized and established in the RIMGIS DB. At this stage, a monitoring techniques that is established in the river management system associated with RIMGIS and minimized the impact of riverbed maintenance (fluctuations) has been studied. In addition, functions and data structure of RIMGIS containing the information of geography and management of the river have been supplemented to make an improvement of the real-time management of the river. Furthermore, a technology that is capable of supplementing RIMGIS has been developed, making it feasible to maintain the river in use of structural method including an structural scheme of cross-section of the river by providing the information of riverbed and cross-section of the river. This is considered to solve an issue of insufficient data on accuracy and based on a lack of information of the river based on the two-dimensional lines, making it feasible to (steadily) improve the function of RIMGIS and to operate management tasks. Therefore, it is highly expected to enhance aforementioned technology of the river information management as a great foundation that maximizes the utilization of the river management to support RIMGIS for the development of national river management data.
Journal of the Institute of Electronics and Information Engineers
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v.50
no.11
/
pp.3-11
/
2013
In smart healthcare service, the accurate and prompt emergency detection and notification are very critical to patients' lives. Since these detection and notification of emergency situation are usually performed by the medical staffs, it is difficult to simultaneously support many patients in real-time. This article presents a methodology for emergency bio-data transmission for smart healthcare using personalized emergency policy. It consists of three steps: In step 1, the bio-data is collected by wireless body area network. In step 2, the decision on emergency is made using personalized emergency policy. In step 3, the emergency message including the health condition information is converted between IEEE 11073 PHD message and HL7 CDA. By doing this, the emergency status of the individual bio-data collected from wireless body area network is detected automatically using personalized emergency policy. When the emergency is detected, the quick emergency rescue service can be provided to the patient by delivering to the emergency notification and the emergency bio-data. We have verified the service and functions of the proposed system architecture by realizing it.
Journal of the Institute of Electronics and Information Engineers
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v.50
no.5
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pp.102-111
/
2013
In this paper, we proposed a $4{\times}4$ block parallel architecture of interpolation for high-performance H.264/AVC Motion Compensation in 4K UHD($3840{\times}2160$) video real time processing. To improve throughput, we design $4{\times}4$ block parallel interpolation. For supplying the $9{\times}9$ reference data for interpolation, we design 2D cache buffer which consists of the $9{\times}9$ memory arrays. We minimize redundant storage of the reference pixel by applying the Search Area Stripe Reuse scheme(SASR), and implement high-speed plane interpolator with 3-stage pipeline(Horizontal Vertical 1/2 interpolation, Diagonal 1/2 interpolation, 1/4 interpolation). The proposed architecture was simulated in 0.13um standard cell library. The maximum operation frequency is 150MHz. The gate count is 161Kgates. The proposed H.264/AVC Motion Compensation can support 4K UHD at 72 frames per second by running at 150MHz.
Kim, Kwang-Deuk;Yun, Chang-Yeol;Jo, Myung-Hee;Kim, Sung-Jae
Journal of the Korean Association of Geographic Information Studies
/
v.15
no.3
/
pp.81-90
/
2012
Recently, with an increased social interest in new and renewable energy resources, together with rapid advancement in IT(information technology) and spatial information technology, there have recently been a lot of attempts to find out methods to make systematic and scientific use of information technology and spatial information technology, depending upon a fusion with GIS(Geographic Information System) spatial information technology in the field of new and renewable energy. This paper developed a suitability analysis system to conduct a correct and precise analysis of an ideal place for wind energy facilities in comprehensive consideration of topographic, economic, and cultural environments. It also used recent spatial information technology including 3D GIS to develop a supportive system for an analysis and decision making of an ideal place for 3D Web GIS-based wind energy facilities like a precise field information implementation, a 3D result display, a 3D object implementation, simulation, and so on. These systems make it possible to build scientific new-renewable energy facilities, to collect, manage and analyze information in an accurate and quantitative manner. In addition, they help serve as a turning point for the construction of a real-time information supply system. Furthermore, they can support rational decision making by making it possible to analyze a variety of forms of field information through building a system for the management of 3D image-based information on new-renewable energy resources.
Journal of Fisheries and Marine Sciences Education
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v.28
no.2
/
pp.323-335
/
2016
The main reason of marine casualties is the human error in respect of ship's operation. The human error of officers in charge of a navigational watch is related to their abilities to handle of navigational equipment. Navigational devices play a key role to help officers decide what to do for safe navigation. Thus, the abilities to handle of navigational equipment mean not only operation of devices but also entire understanding of the system such as interpretation of information obtained from devices, appropriate use of information considering navigational circumstance. Qualification of seafarers is in accordance with STCW and detailed training courses for their qualification are provided by IMO model course series. Recently, ships engaged on international voyages shall be fitted with an ECDIS not later than the first survey on or after 1 July 2018. As increasing use of ECDIS on ships, marine casualties related to ECDIS are on the rise. The primary causes of the accidents are lacking understanding of ECDIS system, wrong presentation of information on display, wrong safety setting by seafarers who use ECDIS, using small-scale chart and missing charts update. As a result of these primary causes, some problems like wrong route planning and use of limited or omitted information occur. It could be happening by inappropriate seafarers' training which is not sufficient to support improving abilities of officers to handle navigational equipment. For efficient training, it is need to develop training courses. Applying full mission simulation system to seafarers' training courses with case studies and best practices which are well-constructed scenarios based on true marine casualties can increase the effect of training. To use the simulation system, it is possible that seafarers are trained under condition that closely resemble real situation. It should be considered that IMO model course be revised depending on the level of seafarers also. It could be helpful for increasing seafarers' abilities of equipment operation in place of accumulation of experience spending much time. In the short term, effort of training courses improvement for seafarers is needed and long term, it should be tried to provide stable system and services relate to ECDIS.
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