• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.294-299
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• 2007

For efficient and accurate diagnosis of ultrasound images, appropriate time gain compensation(TGC) and dynamic range(DR) control of ultrasound echo signals are important. TGC is used for compensating the attenuation of ultrasound echo signals along the depth, and DR controls the image contrast. In recent ultrasound systems, these two factors are automatically set by a system and/or manually adjusted by an operator to obtain the desired image quality on the screen. In this paper, we propose an algorithm to find the optimized parameter values far TGC and DR automatically. In TGC optimization, we determine the degree of attenuation compensation along the depth by dividing an image into vertical strips and reliably estimating the attenuation characteristic of ultrasound signals. For DR optimization, we define a novel cost function by properly using the characteristics of ultrasound images. We obtain experimental results by applying the proposed algorithm to a real ultrasound(US) imaging system. The results verify that the proposed algorithm automatically sets values of TGC and DR in real-time such that the subjective quality of the enhanced ultrasound images may be sufficiently high for efficient and accurate diagnosis.

• 한국게임학회 논문지
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• 제12권5호
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• pp.57-66
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• 2012

본 논문에서는 장면에 어울리도록 유체를 카툰 스타일로 표현할 수 있는 실시간방법을 제안하고자 한다. 실제로 유체는 석양, 낮, 밤에 서로 다른 색상 톤을 보여주고 있고 수심이 낮은 곳에서의 반사 굴절 정도와 수심이 깊은 곳에서의 정도가 상이하며 색상 조차 다르다. 본 논문에서는 광원 수심 지형 시점 등에 적응적으로 유체를 카툰 스타일로 표현하는 방식을 제안한다. 실험은 기존의 방법을 구현하고 제안된 결과와 비교 분석하였다. 이러한 연구는 기존의 카툰 스타일렌더링 방법과 제안하는 카툰 스타일 방법과 동시에 사용하면 게임을 카툰 스타일로 표현할 수 있는 전체 시스템을 제시할 수 있다.

• 대한기관식도과학회지
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• 제2권2호
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• pp.194-199
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• 1996

Laser therapy is becoming an accepted procedure for tissue coagulation and ablation and is especially useful in treating tumors. The laser energy is applied to the tissue of interest through various delivery systems which are introduced percutaneously, via blood vessels, through body openings, or during surgical exposure of the tissue. One of the major obstacles to effective application of lasers has been the lack of reliable method to determine the extent of tissue involvement in real time. Several methods have been proposed for monitoring the tissue response and controlling the laser in real time during laser therapy. Among them, magnetic resonance imaging(MRI) has been introduced to monitor laser-tissue interactions because laser irradiation induces changes not only in the thermal motions of the hydrogen protons within the tissue but also in the distribution and mobility of water and lipids. The buttocks of New Zealand rabbits were treated by KTP and $CO_2$laser(power : 10 watts, exposure time:10 seconds). m images were taken at immediately after lasering, 1 week later, 2 weeks later, and at the same time, tissues were harvested for histopathologic study. We analyzed MR images and histopathologic findigs of laser-treated tissues. The MR images taken immediately after laser treatment showed 3 layer pattern and which was correlated with histopathologic changes. We suggest MRI may become a useful monitoring tools for laser-tissue interaction.

• 대한의용생체공학회:의공학회지
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• 제25권5호
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• pp.391-401
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• 2004

이차원 위상 어레이 변환자를 이용하는 실시간 3차원 영상 시스템은 많은 수의 채널 수를 가지기 때문에 고 비용의 매우 복잡한 빔집속부를 사용하여야 한다. 또한 각 주사선에 대해 초음파를 매번 송수신해야 하므로 볼륨 레이트 또한 낮게 된다. 이를 해결하기 위해 기존에 제안된 교차어레이를 이용한 3차원 영상화 기법은 실시간 3차원 영상을 위한 고속 주사가 가능하고 측방향으로는 동적집속이 가능하지만, 고도방향으로는 송신집속깊이를 제외하고는 고도방향의 해상도가 저하된다는 문제점이 있다. 이러한 문제점을 극복하기 위해 본 논문에서는 합성구경 기반의 교차 어레이를 사용한 3차원 영상화 기법을 제안한다. 제안한 방법에서는 고도방향으로 놓인 일차원 송신어레이의 각 변환소자를 한번에 하나씩 순차적으로 송신하고, 반사된 신호들을 측방향으로 놓인 일차원 수신어레이의 모든 변환소자를 이용하여 수신하게 된다. 수신시 측방향으로는 동적집속, 고도방향으로는 합성구경 기법을 이용하여 빔을 집속함으로써 모든 영상 점에 대해 측방향과 고도방향 모두 동적집속된 효과를 얻을 수 있다. 또한, 제안한 방법은 고도방향으로 합성구경 기법을 이용함으로써 송신어레이 변화소자 개수만큼의 초음파 송수신 과정을 통해 관심 영역의 입제영상을 임의의 요구되는 단면영상 수를 이용하여 구성할 수 있다. 제안한 방법을 통해 기존의 고정집속 기반의 교차어레이를 이용한 3차원 영상화 기법과 비교하여 측방향으로는 동일하고 고도방향으로는 훨씬 우수한 해상도의 영상을 획득할 수 있음을 컴퓨터 모사실험을 통해 점증하였다. 또한 동반논문에서는 제안한 방법에 비해 송신전력과 고도방향 해상도를 더욱 향상시킬 수 있는 선형파면 기반의 합성구경 기법을 제안한다.

• ETRI Journal
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• 제32권5호
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• pp.657-664
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• 2010

Many embedded multimedia systems employ special hardware blocks to co-process with the main processor. Even though an efficient handling of such hardware blocks is critical on the overall performance of real-time multimedia systems, traditional real-time scheduling techniques cannot afford to guarantee a high quality of multimedia playbacks with neither delay nor jerking. This paper presents a hardware-aware rate monotonic scheduling (HA-RMS) algorithm to manage hardware tasks efficiently and handle special hardware blocks in the embedded multimedia system. The HA-RMS prioritizes the hardware tasks over software tasks not only to increase the hardware utilization of the system but also to reduce the output jitter of multimedia applications, which results in reducing the overall response time.

• Journal of information and communication convergence engineering
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• 제14권1호
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• pp.51-56
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• 2016

In this paper, we present a three-dimensional (3-D) automatic target recognition system based on optical integral imaging reconstruction. In integral imaging, elemental images of the reference and target 3-D objects are obtained through a lenslet array or a camera array. Then, reconstructed 3-D images at various reconstruction depths can be optically generated on the output plane by back-projecting these elemental images onto a display panel. 3-D automatic target recognition can be implemented using computational integral imaging reconstruction and digital nonlinear correlation filters. However, these methods require non-trivial computation time for reconstruction and recognition. Instead, we implement 3-D automatic target recognition using optical cross-correlation between the reconstructed 3-D reference and target images at the same reconstruction depth. Our method depends on an all-optical structure to realize a real-time 3-D automatic target recognition system. In addition, we use a nonlinear correlation filter to improve recognition performance. To prove our proposed method, we carry out the optical experiments and report recognition results.

• Archives of Plastic Surgery
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• 제42권5호
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• pp.626-629
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• 2015

Peripheral nerve injuries remain a challenge for reconstructive surgeons with many patients obtaining suboptimal results. Understanding the level of injury is imperative for successful repair. Current methods for distinguishing healthy from damaged nerve are time consuming and possess limited efficacy. Confocal laser endomicroscopy (CLE) is an emerging optical biopsy technology that enables dynamic, high resolution, sub-surface imaging of live tissue. Porcine sciatic nerve was either left undamaged or briefly clamped to simulate injury. Diluted fluorescein was applied topically to the nerve. CLE imaging was performed by direct contact of the probe with nerve tissue. Images representative of both damaged and undamaged nerve fibers were collected and compared to routine H&E histology. Optical biopsy of undamaged nerve revealed bands of longitudinal nerve fibers, distinct from surrounding adipose and connective tissue. When damaged, these bands appear truncated and terminate in blebs of opacity. H&E staining revealed similar features in damaged nerve fibers. These results prompt development of a protocol for imaging peripheral nerves intraoperatively. To this end, improving surgeons' ability to understand the level of injury through real-time imaging will allow for faster and more informed operative decisions than the current standard permits.

• Molecules and Cells
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• 제42권5호
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• pp.418-425
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• 2019

Multicistronic elements, such as the internal ribosome entry site (IRES) and 2A-like cleavage sequence, serve crucial roles in the eukaryotic ectopic expression of exogenous genes. For utilization of multicistronic elements, the cleavage efficiency and order of elements in multicistronic vectors have been investigated; however, the dynamics of multicistronic element-mediated expression remains unclear. Here, we investigated the dynamics of encephalomyocarditis virus (EMCV) IRES- and porcine teschovirus-1 2A (p2A)-mediated expression. By utilizing real-time fluorescent imaging at a minute-level resolution, we monitored the expression of fluorescent reporters bridged by either EMCV IRES or p2A in two independent cultured cell lines, HEK293 and Neuro2a. We observed significant correlations for the two fluorescent reporters in both multicistronic elements, with a higher correlation coefficient for p2A in HEK293 but similar coefficients for IRES-mediated expression and p2A-mediated expression in Neuro2a. We further analyzed the causal relationship of multicistronic elements by convergent cross mapping (CCM). CCM revealed that in all four conditions examined, the expression of the preceding gene causally affected the dynamics of the subsequent gene. As with the cross correlation, the predictive skill of p2A was higher than that of IRES in HEK293, while the predictive skills of the two multicistronic elements were indistinguishable in Neuro2a. To summarize, we report a significant temporal correlation in both EMCV IRES- and p2A-mediated expression based on the simple bicistronic vector and real-time fluorescent monitoring. The current system also provides a valuable platform to examine the dynamic aspects of expression mediated by diverse multicistronic elements under various physiological conditions.

• 한국전자파학회논문지
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• 제22권11호
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• pp.1054-1062
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• 2011

무인 차량의 야지 자율 주행을 위한 근거리 초광대역 bistatic 레이다에 적합한 시간 영역 영상화 기법의 구현에 대해 기술한다. 기존의 SAR(Synthetic Aperture Radar) 영상화 기법에서 주파수 영역에 기반을 둔 방법은 원전계 조건을 만족하는 응용 분야에는 잘 적용되지만, 근거리에 적용할 경우 근사화에 따른 위상 오차가 크게 되어 영상의 품질을 떨어뜨린다. 따라서 근거리 영상 레이다에서는 시간 영역에 기반을 둔 back-projection 방법이 적합하다. 그러나 back-projection의 경우 수행 시간이 매우 긴 단점이 있다. 따라서 시간 영역에 기반을 두고 영상의 품질은 back-projection과 유사하며, 수행 시간을 줄일 수 있는 방법으로 개발된 것이 FFBP(Fast Factorized Back-Projection) 방법이다. 야지에서 획득한 레이다 원시데이터를 사용하여 back-projection 방법과 FFBP 방법을 구현하고 영상의 품질 및 수행 시간을 비교하여 bistatic 전방 관측 레이다의 시간 영역 영상화 기법의 적용 가능성을 입증한다.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2002년도 International Meeting on Information Display
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• pp.285-288
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• 2002

We propose the use of synchronously moving micro-optics (lenslet arrays) for image pickup and display in three-dimensional integral imaging to overcome the upper resolution limit imposed by the Nyquist sampling theorem. With the proposed technique, we present an all-optical three-dimensional integral imaging projector. An optically addressed spatial light modulator is used, which potentially provides better image resolution than the conventional CCD and liquid crystal display pair. We present experimental results using a liquid crystal light valve.