• Journal of Korea Multimedia Society
• /
• v.14 no.1
• /
• pp.54-75
• /
• 2011

PoC(Push-to-talk Over Cellular) is an integrated technology of group voice calls, video calls and internet based multimedia services. If a PoC user can not participate in the PoC session for various reasons such as an emergency situation, lack of battery capacity, then the user can use the PoC Box which has a similar functionality to the MM Box in the MMS(Multimedia Messaging Service). The RTSP(Real-Time Streaming Protocol) method is recommended to be used when there is a transmission session between the PoC box and a terminal. Since the existing VOD service uses a wired network, the packet size of RTSP-based VOD service is huge, however, the PoC service has wireless communication environments which have general characteristics to be used in RTSP method. Packet loss in a wired communication environments is relatively less than that in wireless communication environment, therefore, a buffering latency occurs in PoC service due to a play-out delay which means an asynchronous play of audio & video contents. Those problems make a user to be difficult to find the information they want when the media contents are played-out. In this paper, the following techniques and methods were proposed and their performance and superiority were verified through testing: cross-over dual reception buffering technique, advance partition multi-reception buffering technique, and on-demand multi-reception buffering technique, which are designed for effective picking up of information in media content being transmitted in short amount of time using RTSP when a user searches for media, as well as for reduction in playback delay; and same-priority packetization transmission method and priority-based packetization transmission method, which are media data packetization methods for transmission. From the simulation of functional evaluation, we could find that the proposed multiple receiving buffering and packetizing methods are superior, with respect to the media retrieval inclination, to the existing single receiving buffering method by 6-9 points from the viewpoint of effectiveness and excellence. Among them, especially, on-demand multiple receiving buffering technology with same-priority packetization transmission method is able to manage the media search inclination promptly to the requests of users by showing superiority of 3-24 points above compared to other combination methods. In addition, users could find the information they want much quickly since large amount of informations are received in a focused media retrieval period within a short time.

• Journal of the Society of Disaster Information
• /
• v.11 no.4
• /
• pp.556-569
• /
• 2015

With about 75% of the population of Korea criticizing the government's disaster policy and a failure to respond to large-scale emergency like the Sewol ferry sinking means that there is a deep distrust in the government. In order to prevent dreadful disasters such as the Sewol ferry sinking, it is important to secure a prime time with respect to disaster safety. Improving crisis management skills and managerial role of police officers who are in close proximity to the people is necessary for the success of disaster management. With disaster management as one of the most essential missions of the police, as a part of a national crisis management, a step by step strengthening of the disaster safety management system of the police is necessary, as below. First, at the prevention phase, law enforcement officers were not injected into for profit large-scale assemblies or events, but in the future the involvement, injection should be based on the level of potential risk, rather than profitability. In the past and now, the priortiy was the priority was on traffic flow, traffic communication, however, the paradigm of traffic policy should be changed to a safety-centered policy. To prevent large-scale accidents, police investigators should root out improper routines and illegal construction subcontracting. The police (intelligence) should strengthen efforts to collect intelligence under the subject of "safety". Second, with respect to the preparatory phase, on a survey of police officers, the result showed that 72% of police officers responded that safety management was not related to the job descriptions of the police. This, along with other results, shows that the awareness of disaster safety must be adopted by, or rather changed in the police urgently. The training in disaster safety education should be strengthened. A network of experts (private, administrative, and police) in safety management should be established to take advantage of private resources with regard to crisis situtions. Third, with respect to the response phase, for rapid first responses to occur, a unified communication network should be established, and a real-time video information network should be adopted by the police and installed in the police situation room. Fourth, during the recovery phase, recovery teams should be injected, added and operated to minimize secondary damage.

• Journal of Korean Society of Transportation
• /
• v.26 no.3
• /
• pp.31-40
• /
• 2008

There have been a lot of efforts to find more accurate evaluation methods for traffic signal control effectiveness for a long period of time. Nowadays a newly advanced method called HILSS, 'Hardware-in-the-Loop-Simulation System', is used to evaluate the overall traffic control's effectiveness including physical control environments like communication conditions, hardware performance, controller's mechanical operations and so on. In this study, an Online-HILSS model has been developed, which runs on CORSIM(5.0) micro traffic simulation model on-lined to COSMOS. For the verification of the model, three tests are performed as follows; (1) a comparison of TMC's timing plan with the simulated green interval, (2) as a case study, a delay distribution comparison of the online simulation with the CORSIM stand-alone simulation. The result of the first test shows that the model can run the simulation green interval by TMC's timing plan correctly. The result of second test shows that the online simulation of the model brings the same simulation results with the CORSIM offline simulation in case of the same timing plan. These results mean that the online evaluation model could be a reliable tool to measure a real-time signal control effectiveness of a wide area street network with the HILSS method.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.5
• /
• pp.2667-2672
• /
• 2016

Background: Virtually all cases of cervical cancer are caused by persistent infections with a restricted set of human papillomaviruses (HPV). Cancer of the cervix is the third or even the second most common cancer in women worldwide, more than 85% of the cases occurring in developing countries, such as China and India, including the Republic of Kazakhstan. The purpose was to determine the HPV type distribution to evaluate efficacy of vaccination and adjust cancer prevention strategy in Western Kazakhstan in the future. Materials and Methods: A retrospective analysis was conducted of data obtained from PCR laboratories in 4 regional centers for the time period covering 12 months, 2013-2014, using AmpliSens$^{(R)}$ Real-Time PCR kits for HPV testing of 12 genotypes (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59). Results: A total of 1,661 persons were HPV tested within 2013-14, but a proprotion examined for 16 and 18 genotypes only (563) was not been included for statistic analysis of distribution and ratio of the most common genotypes. Males accounted for only a small number (N=90 in total). Conclusions: Total number of the HPV-positive appeared to be 26.0%, or 286 of N=1098. Types distribution was as follows: type 16 (10.7%), 39 (5.83%), 51 (5.27%), 31 (4.85%), 56 (4.58%), 18 (3.61%), 59 (2.64%), 58 (2.22%), 35 (1.94%), 33 (1.25%). Overall the HPV infection was highest in 16-29 years old (62.4%) and decreased with age. Total prevalence of the HR-HPVs amongst male population was 21.4% with top five types 16, 18, 39, 51, 31. Trends forcorrelations between Aktau site and type 33 (Cramer's V 0.2029), between Caucasian ethnicity and type 33 (Cramer's V .1716), and between European ethnicities in Uralsk and type 45 (Cramer's V .1752) were found. Of N 563 tested separately for 16 or 18 types, 13.6% were positive. As a whole, the distribution of 16/18 types had a ratio of 3.53:1. Given the vaccine-targeted type 16 is widely spread amongst this regional population, HPV immunization program of adolescent girls 10-13 years should be implemented appropriately.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.11
• /
• pp.711-717
• /
• 2017

The railway is a public transportation system that provides large-scale passenger transportation and service, whose reliability and safety is the top priority. The wiring of railway vehicles is classified into train control lines (train lines) and communication lines. The train lines are used for input / output signals related to vehicle driving and safety functions, and the communication lines are used for the input / output signals for passenger services such as broadcasting. In order to measure the reliability of railway vehicles, a train line is applied to the input / output interface of the control signals between the electric control devices in the vehicle, and there are many electromechanical devices such as relays and contactors for the control logic. In fact, since the vehicle control circuit is composed of several thousand contacts, it is difficult to check for errors such as contact failure, and it is impossible to check the real-time status, so a lot of manpower and time is required for regular maintenance. Therefore, we analyze the current state of the train line design of the electric equipment used for driving and services in domestic railway cars and propose three wiring reduction methods to improve it. Based on the analysis of domestic electric vehicles, it was confirmed that the wiring reduction effect is 35% or more.

• IMMUNE NETWORK
• /
• v.12 no.2
• /
• pp.58-65
• /
• 2012

Background: A cell line with transfected Wilms' tumor protein 1 (WT1) is has been used for the preclinical evaluation of novel treatment strategies of WT1 immunotherapy for leukemia due to the lack of appropriate murine leukemia cell line with endogenous WT1. However, silencing of the transgene occurs. Regarding the effects of hypomethylating agents (HMAs) on reactivation of silenced genes, HMAs are considered to be immune enhancers. Methods: We treated murine WT1- transfected C1498 (mWT1-C1498) with increasing doses of decitabine (DAC) and azacitidine (AZA) to analyze their effects on transgene reactivation. Results: DAC and AZA decreased the number of viable cells in a dose- or time-dependent manner. Quantification of WT1 mRNA level was analyzed by real-time polymerase chain reaction after mWT1-C1498 treated with increasing dose of HMA. DAC treatment for 48 h induced 1.4-, 14.6-, and 15.5-fold increment of WT1 mRNA level, compared to untreated sample, at 0.1, 1, and $10{\mu}M$, respectively. Further increment of WT1 expression in the presence of 1 and $10{\mu}M$ DAC was evident at 72 h. AZA treatment also induced up-regulation of mRNA, but not to the same degree as with DAC treatment. The correlation between the incremental increases in WT1 mRNA by DAC was confirmed by Western blot and concomitant down-regulation of WT1 promoter methylation was revealed. Conclusion: The in vitro data show that HMA can induce reactivation of WT1 transgene and that DAC is more effective, at least in mWT1-C1498 cells, which suggests that the combination of DAC and mWT1-C1498 can be used for the development of the experimental model of HMA-combined WT1 immunotherapy targeting leukemia.

• Journal of the Institute of Electronics Engineers of Korea CI
• /
• v.49 no.1
• /
• pp.29-38
• /
• 2012

Due to the rapid development of network environment and wireless communication technology, the distribution of digital video has made easily and the importance of the protection for digital video has been increased. This paper proposes the digital video encryption system based on multiple chaos maps for MPEG-2 video encoding process. The proposed method generates secret hash key of having 128-bit characteristics from hash chain using Tent map as a basic block and generates $8{\times}8$ lattice cipher by applying this hash key to Logistic map and Henon map. The method can reduce the encryption overhead by doing selective XOR operations between $8{\times}8$ lattice cipher and some coefficient of low frequency in DCT block and it provides simple and randomness characteristic because it uses the architecture of combining chaos maps. Experimental results show that PSNR of the proposed method is less than or equal to 12 dB with respect to encrypted video, the time change ratio, compression ratio of the proposed method are 2%, 0.4%, respectively so that it provides good performance in visual security and can be applied in real time.

• Molecules and Cells
• /
• v.37 no.7
• /
• pp.547-553
• /
• 2014

Glioblastoma multiforme (GBM) is one of the most common brain malignancies and has a very poor prognosis. Recent evidence suggests that the presence of cancer stem cells (CSC) in GBM and the rare CSC subpopulation that is resistant to chemotherapy may be responsible for the treatment failure and unfavorable prognosis of GBM. A garlic-derived compound, Z-ajoene, has shown a range of biological activities, including anti-proliferative effects on several cancers. Here, we demonstrated for the first time that Z-ajoene specifically inhibits the growth of the GBM CSC population. CSC sphere-forming inhibition was achieved at a concentration that did not exhibit a cytotoxic effect in regular cell culture conditions. The specificity of this inhibitory effect on the CSC population was confirmed by detecting CSC cell surface marker CD133 expression and biochemical marker ALDH activity. In addition, stem cell-related mRNA profiling and real-time PCR revealed the differential expression of CSC-specific genes, including Notch, Wnt, and Hedgehog, upon treatment with Z-ajoene. A proteomic approach, i.e., reverse-phase protein array (RPPA) and Western blot analysis, showed decreased SMAD4, p-AKT, 14.3.3 and FOXO3A expression. The protein interaction map (http://string-db.org/) of the identified molecules suggested that the AKT, ERK/p38 and $TGF{\beta}$ signaling pathways are key mediators of Z-ajoene's action, which affects the transcriptional network that includes FOXO3A. These biological and bioinformatic analyses collectively demonstrate that Z-ajoene is a potential candidate for the treatment of GBM by specifically targeting GBM CSCs. We also show how this systemic approach strengthens the identification of new therapeutic agents that target CSCs.

• Journal of Korean Society for Geospatial Information Science
• /
• v.9 no.2 s.18
• /
• pp.29-36
• /
• 2001

The purpose of this paper is to describe the Disaster Management System Development of Enterprise GIS at the Kangwon Province in Korea. This project is included into 'the Kangwon Enterprise GIS 21 plan'. The Division of Disaster Management is in the middle of the 2-year project of the Disaster Management System development, appropriate for business performed at the Departments of Forestry, Culture, Environment, Tourism, etc. At the 1st phase of CIS implementation, for more than half a year we focused on the necessity of management of disasters. In the planning process, we needed long-term information on the whole area of Kangwon. In the assessment and response processes, we needed real-time data from Korean Meteorological Administration and other agencies. All the above information was carefully studied and referred to. ESRI's new GIS technologies solve the natural hazard/disaster problems. For example, hazardous materials routing often needs to be found the least expensive path through a roadway network. In the circumstances given, we can choose the departure point and destination of the vehicle, which carries the materials. It's also possible to minimize overall risk and costs of disaster problems by making a plan of people and possessions evacuation from the disaster area in short time limits. We can meet all the above goals using the latest ESRI's technologies.

• Journal of the Korea Society for Simulation
• /
• v.26 no.1
• /
• pp.21-38
• /
• 2017

Information Centric Networking is changing the way how content is being transmitted. The shift from IP and host based networking towards content based networking scenario is growing day by day. Many researches have been done about different frameworks of ICN. Caching is an important part of ICN and many researchers have also proposed different ways for caching the data. With caching of data in intermediate devices like the network devices as well the user devices in some cases, the issue of content security as well as the role of the content producer becomes a major concern. A modified ICN architecture based on the current Content Centric Networking (CCN) model is presented in the paper. The architecture mainly focuses on involving the content producer in content delivery in the real time. The proposed architecture provides better security aspects for the CCN architecture. Apart from security the paper will also consider the issue of applicability of CCN architecture to replace the TCP/IP based architecture. The efficiency of the proposed architecture is compared with the previous CCN architecture based on the response time for a content delivery which shows very comparable level of efficiency. The paper than analyzes different beneficial aspects of the proposed architecture over the current architecture.