• 핵의학기술
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• 제20권2호
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• pp.75-79
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• 2016

Purpose The ASAN Medical Center, Nuclear Medicine performs TSH (Thyroid stimulating hormone) and FT4 (Free Thyroxine) tests 8 times per day. Accordingly, 70 ~ 80 kit tubes are consumed every day for the measurements and the time consumed for reagent dispensing averages over 170 seconds, where the TAT (turnaround time) may be effected when the number of test samples is larger than expected. Therefore, the following test was conducted with the purpose to reduce the number of kit tubes consumed, and reduce the time for reagent dispensing. Materials and Methods The test is based on applying the same reagent for tests where the number of samples is 30 or less. The test for TSH was conducted 9 times from July $1^{st}$ 2015 to July $10^{th}$ 2015. The test for FT4 was conducted 4 times from June $18^{th}$ 2015 to June $22^{nd}$, 2015. Standard Solution No.2 (0.153 uU/mL) and No.5 (4.96 uU/mL) was selected as the two-point standards for the TSH test, and Standard Solution No.3 (0.777 ng/dL) and No.4 (2.044 ng/dL) was selected as the two-point standards for the FT4 test. 38 test samples were subject to correlation analysis. Results For TSH, the result of the normal test shows ranges of 0.20 ~ 0.37 uU/mL for Control1, 0.53 ~ 0.71 uU/mL for Control2, and 6.77 ~ 7.94uU/mL for Control3, while the result of two-point calibration curve test shows ranges of 0.18 ~ 0.27 uU/mL for Control1, 0.53 ~ 0.71 uU/mL for Control2, and 7.30 ~ 8.52 uU/mL for Control3. For FT4, the result of the normal test shows ranges of 0.85 ~ 0.94 ng/dL for Control1 and 4.23 ~ 4.57 ng/dL for Control2, while the result of two-point calibration curve test shows ranges of 0.61 ~ 0.75 ng/dL for Control1 and 3.88 ~ 5.71 ng/dL for Control2. For TSH, the CV% of the normal test for Control1, Control2 and Control3 are 10.5, 3.3 and 3.6 respectively, while the CV% of the two-point calibration curve test for Control1 and Control1 are 12.4, 8.2 and 5.1 respectively. The result shows an outstanding correlation of TSH: y = 0.9985x - 0.0459 $R^2=0.9986$. For FT4, the CV% of the normal test for Control1 and Control2 are 0.70 and 0.71 respectively, while the CV% of the two-point calibration curve test for Control1 and Control1 are 8.7 and 16.2 respectively. The result shows an outstanding correlation of FT4: y = 1.2674x - 0.1133 $R^2=0.9824$. Conclusion The two-point calibration curve can be efficiently applied for TSH in cases where the number of test samples is not large, since the number of samples to be re-tested increases when the result is abnormal from the calibration curve. The two-point calibration curve test should not be applied for FT4 where the results do not consistently comply with the quality assessment range. Depending on how the two-point calibration curve is applied, up to 5 test tubes can be conserved per test, and the reduced time for reagent dispensing is anticipated to have a positive effect on the TAT (turnaround time).

• The Korean Journal of Ceramics
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• 제3권2호
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• pp.105-109
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• 1997

The effects of surface conditions of the C-2 cemented carbide substrate on the adhesion of diamond film were investigated. The substrates were pretreated for different times with Murakami's reagent and then the acid solution of an H2SO4-H2O2. The adhesion strength was estimated by a peeling area around the Rockwell-A indentation. The cutting performance of the diamond-coated tools was evaluated by measuring flank wears in dry turning of Al-17% Si alloy. The morphology of deposited diamond crystallites was dominated by (111) and (220) surfaces with a cubooctahedral shape. The diamond film quality was hardly affected by the surface conditions of the substrate. The variation of tool life with longer substrate etching times resulted from a compromies between the increase of film adhesion at the interface and the decrease of toughness at the substrate surface. The coated tools were mainly deteriorated by chipping and flaking of the diamond film form a lock of adhesion strength, differently from the wear phenomena of PCD tools.

• 한국세라믹학회지
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• 제16권1호
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• pp.13-20
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• 1979

High purity alumina has been extracted form low grade Korean alunite. Alunite ore was treated by 15% $NH_4OH$ solution, followed by 10% $H_2SO_4$ leaching and metallic impurities such as Fe and Ti were removed by solvent extraction method. Alumina prepared by the extraction process was 99.9% in purity. Hot Petroleum Drying Method has been employed for the preparation of uniformly fine alumina powder, using chemical reagent aluminum sulfate and ammonium aluminum sulfate extrated from Korea alunite. The sinterability of alumina powder prepared by Hot Petroleum Drying Method was shown to be improved in comparison with the one treated by other methods such as ball milling method, but dry pressing was difficult due to the agglomeration of calcined powder. The best slip of alumina powder prepared by Hot Petroleum Drying Method contained a lower soild content than the one treated by other methods. The alumina body formed by soild and drain casting with the former alumina powder showed a higher sintered density.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2000년도 춘계학술대회 논문집 전자세라믹스 센서 및 박막재료 반도체재료 일렉트렛트 및 응용기술
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• pp.139-142
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• 2000

Displacement current was generated in the light stimulus. Solution of azobenzene molecules (8A5H) have to character trans-to-cis. The Maxwell displacement current measuring technique has been applied for the investigation of azobenzene organic thin films under alternating photoirradiation with ultraviolet($\lambda_1$) and visible($\lambda_2$) light. also, As laser beam(630~670nm) investigate light response. As result, ultraviolet($\lambda_1$) and visible($\lambda_2$) light see photoisomerization response, but laser beam not appear photoisomerization in current that differ wave range reagent.

• 한국염색가공학회지
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• 제9권1호
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• pp.33-43
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• 1997

This study was carried out to investigate increasing the neutral substantivity of anionic dyes for cationic-modified cotton fabric treatied with cationic agent. In the present study 3-chloro-2-hydroxypropyltrimethyl ammonium chloride for reactive cationic agent was produced by reaction of epichlorohydrine with trimethylamine hydrochloride. 3-chloro-2-hydroxypropyltrimethylammonium chloride was converted in an aqueous solution of sodium hydroxide into glycidyltrimethylammonium chloride. By treating with this epoxy reagent the hydroxyl groups of cotton fabric was modified to trimethylammonium group through ether linkage. The introduction of new cationic sites into cotton fabric by pretreating with cationic agent improves the substantivity of anionic dyes with the cotton in dyebath. Dyeablity of the modified cotton fabric for direct and reactive dyes was much improved in a non-electrolytic or a little electrolytic dyebath and was proportional to the concentration of cationic agent.

• Journal of Pharmaceutical Investigation
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• 제2권1호
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• pp.14-17
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• 1972

Spectrophotometric determination of isonicotinic acid hydrazide sodium methane sulfonate was examined and a new method has been established. Isonicotinic acid hydrazide sodium methane sulfonate reacts with acetylacetone solution (NASH Reagent) to produce a yellow dye, which exhibits absorption maximum at about $412\;m{\mu}$. Limits of masurement of isonicotinic acid hydrazide sodium methane sulfonate was $20-100{\mu}g/ml$. By this method isonicotinic acid hydrazide methane sulfonate can be determined in the presence of isonicotinic acid hydrazide.

• Journal of Pharmaceutical Investigation
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• 제31권3호
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• pp.197-200
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• 2001

Lectin-conjugated ellagitannin (LET), a newly introduced melanoma-specific antitumor agent which has been synthesized by conjugation of wheat germ agglutinin as a lectin with praecoxin A as an ellagitannin, was encapsulated into sterically stabilized liposomes (SSL). Modified Folin phenol method was established for the quantitation of LET contents in liposomal formulations protein employing the standard calibration curve with bovine serum albumin. After removal of phospholipid by organic solvent extraction, which interferes the specific selectivity of the Folin-Ciocalteu reagent with the protein, recovery of LET was $94.5{\pm}2.3%$ and the encapsulation efficiency was revealed as $37.8{\pm}5.9%$ for 2.5 mg/ml LET solution.

• Nuclear Engineering and Technology
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• 제19권4호
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• pp.242-248
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• 1987

레이저를 이용한 형광분석 방법과 형광의 세기를 증대시켜주는 'Fluran' 용액을 가함으로써 용액속에 존재하는 미량의 우라늄을 정착하고 신속하게 분석할 수 있는 새로운 장치를 개발하였다. 표준용액의 첨가 방법을 이용하여 시료의 조성 변화에 따른 형광의 방해효과를 보정할 수 있었고 5%이내의 정밀도를 갖는 0.1ppb의 측정 하한치를 얻을 수 있었다. 또한 여러 종류의 시료에 대하여 레이저를 이용한 형광분석 방법의 결과와 다른 측정 방법에 의한 결과를 상호 비교, 분석하였다.

• 대한화학회지
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• 제15권6호
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• pp.378-384
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• 1971

A new analytical reagent 8-(p-ethylbenzenesulfonamido)quinoline(EBSQ) has been synthesized, and identified its structure. EBSQ forms copper chloroform-soluble complex in a basic solution (pH = 7.5∼10.5). The other optimum conditions for the spectrophotometric study of Cu-EBSQ have been established at 380 $m{\mu}$. Beer's law is followed in the concentration range of 0~44.5 ${\mu}g$ per 10 ml of chloroform. The composition of complex has been found to be $Cu(EBSQ-H)_2$and the over-all instability constant is calculated to be $1.22{\times}10^{-7}$. The absorption coefficient of the $Cu(EBSQ-H)_2$ complex is ${\varepsilon}$ = 15,800.

• 대한화학회지
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• 제7권4호
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• pp.299-303
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• 1963

A method of the colorimetric determination of titanium has been developed, based on the fact (IV) forms a stable blue complex with methylthymolblue(MTB) which is suitable for spectrophotometric determination of titanium in the concentration range of 0.2 to 22 $\mu$g per ml as $TiO_2$. The determination was carried out in the solution of pH range of 2.6 to 3.6, and the absorbancy of complex was at 600m$\mu$ with Coleman spectrophotometer. Titanium forms a 1:1 complex with MTB, which has a molar absorptivity, $1.1{\times}10^4$ at 600m\mu$. The effects of hydrogen ion concentration, reagent concentration, stability of complex, and hydrolysis were studied. Most of cations do not interfere seriously; however, many of anions such as oxalate, citrate, phosphate, chloride interfere in this determination.