• Tunnel and Underground Space
• /
• v.16 no.4 s.63
• /
• pp.307-312
• /
• 2006

Radionuclide released from corroded container migrates through groundwater flow pathway in the underground rock. Therefore it is important to study the groundwater flow analysis for total system performance assessment of a HLW repository. In this study assuming a geological change of underground rock in future, the two dimensional groundwater flow analysis is done by the NAMMU, the assessment code for groundwater flow in porous media. Assuming the hypothetical repository with the reactivation of fault in the vicinity of it, the effect of change in aperture and permeability by reactivation of fault around a repository on groundwater pathway is studied.

• Radiation Oncology Journal
• /
• v.28 no.2
• /
• pp.106-110
• /
• 2010

Reactivation of the hepatitis B virus (HBV) is a well-recognized complication in patients with chronic HBV infection who receive cytotoxic or other immunosuppressive therapy. In cases of patients treated by radiotherapy however, only a few of such reports exist and most of these include the patients previously treated by chemotherapy or transarterial chemoembolization. The results of this study point to a case of a patient with reactivation of HBV after radiotherapy alone. This study shows the possibility of HBV reactivation by partial hepatic irradiation alone hence, special attention should be paid to patients with HBV disease.

• Toxicological Research
• /
• v.4 no.1
• /
• pp.47-53
• /
• 1988

Cholera toxin and dibutyryl cyclic adenosine 3', 5'-monophosphate(db-cAMP) increased the rate and number of infections units produced in the in vitro reactivation of latent herpes simplex virus, whereas adenosine diminished them. cAMP concentration in latently infected trigeminal ganglia of mice was greatly increased by cholera toxin but was not affected by adenosine.

• Journal of Yeungnam Medical Science
• /
• v.33 no.1
• /
• pp.1-7
• /
• 2016

The two distinctive clinical features of varicella-zoster virus (VZV) are varicella (chickenpox) by primary infection and zoster (singles) by the reactivation of latent infection. In addition to the two typical clinical symptoms mentioned above, diverse clinical manifestations have been reported as a result of VZV reactivation, including chronic radicular pain without rash, visual loss, facial palsy, dysphagia, sore throat, odynophagia, otalgia, hearing loss, dizziness, headache, hemiplegia, etc. Most of these symptoms are derived from neuropathy and vasculopathy of affected nerves and arteries. Diagnosis of VZV disease can be difficult if there is no appearance of a skin rash during development of atypical symptoms. In addition to natural infection, vaccination and anti-viral agent treatment have influenced the changes of epidemics and clinical presentations of varicella and zoster. In this article, diverse clinical manifestations caused by VZV reactivation, particular without skin rash, are reviewed.

• Korean Journal of Microbiology
• /
• v.25 no.2
• /
• pp.117-121
• /
• 1987

The ozone-induced reactivation factor for ozonated or UV-irradiated T3 phage was determined in defferent bacterial strains of Escherichia coli B resistant of sensitive to ozone. Our results suggest that ozone is a weak, if any at all, inducer of the Weigle reactivation, one of the SOS functions. This is in agreement with other studies which have suggested that thes agent is probably a weak inducer of the SOS functions.

• FOCUS: LIFE SCIENCE
• /
• no.1
• /
• pp.8.1-8.3
• /
• 2024

Ultra-high performance liquid chromatography (UHPLC) systems are integral to modern analytical laboratories, necessitating careful maintenance and operation protocols to ensure optimal performance. This document provides comprehensive guidelines for the proper shutdown and reactivation of UHPLC systems to prevent damage and maintain operational efficiency. • Shutdown: Remove the column and replace it with a union to avoid blockages. Flush the system with a compatible solvent mix, clean mobile phase reservoirs to prevent microbial growth, flush the pump with storage solvent, and clean the autosampler, including the needle and injection port. • Reactivation: Inspect the system for wear or damage, gradually reintroduce mobile phases starting with a weak solvent, reinstall the column securely, and perform system checks on baseline stability, pressure consistency, and detector performance. By adhering to these guidelines, laboratories can ensure the longevity and reliability of their UHPLC systems, maintaining high analytical performance and minimizing downtime. These procedures help prevent common issues such as blockages, contamination, and component wear, thereby supporting efficient and accurate analytical operations.

• Journal of Microbiology and Biotechnology
• /
• v.27 no.1
• /
• pp.189-196
• /
• 2017

Kaposi's sarcoma-associated herpesvirus (KSHV) is associated with formation of Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma. Replication and transcription activator (RTA) genes are expressed upon reactivation of KSHV, which displays a biphasic life cycle consisting of latent and lytic replication phases. RTA protein expression results in KSHV genome amplification and successive viral lytic gene expression. Transcriptional activity of viral lytic genes is regulated through epigenetic modifications. In Raji cells latently infected with Epstein-Barr virus, various modifications, such as acetylation and methylation, have been identified at specific lysine residues in histone H4 during viral reactivation, supporting the theory that expression of specific lytic genes is controlled by histone modification processes. Data obtained from chromatin immunoprecipitation and quantitative real-time PCR analyses revealed alterations in the H4K8ac and H4K20me3 levels at lytic gene promoters during reactivation. Our results indicate that H4K20me3 is associated with the maintenance of latency, while H4K8ac contributes to KSHV reactivation in infected TREx BCBL-1 RTA cells.

• Tunnel and Underground Space
• /
• v.26 no.2
• /
• pp.59-67
• /
• 2016

In this paper, we perform a numerical analysis to evaluate the potential of fault reactivation during gas production from hydrate bearing sediments and the moment magnitude of induced seismicity. For the numerical analysis, sequential coupling of TOUGH+Hydrate and FLAC3D was used and the change in effective stress and consequent geomechanical deformation including fault reactivation was simulated by assuming that Mohr-Coulomb shear resistance criterion is valid. From the test production simulation of 30 days, we showed that pore pressure reduction as well as effective stress change hardly induces the fault reactivation in the vicinity of a production well. We also investigated the influence of stress state conditions to a fault reactivation, and showed that normal fault stress regime, where vertical stress is relatively greater than horizontal, may have the largest potential for the reactivation. We tested one simulation that earthquake can be induced during gas production and calculated the moment magnitude of the seismicity. Our calculation presented that all the magnitudes from the calculation were negative values, which indicates that induced earthquakes can be grouped into micro-seismic and as small as hardly perceived by human beings. However, it should be noted that the current simulation was carried out using the highly simplified geometric model and assumptions such that the further simulations for a scheduled test production and commercial scale production considering complex geometric conditions may produce different results.

• Journal of Korean Society of Water and Wastewater
• /
• v.21 no.6
• /
• pp.671-678
• /
• 2007

2-methylisoborneol (MIB) is a musty odor compound produced as a secondary metabolite by some cyanobacteria and actinomycetes. It is lead to distrust in tap water due to taste and odor. It is well known that activated carbon (AC) adsorption is the best available technology to remove 2-MIB and geosmin. In this study, physical characteristics of virgin AC and reactivated AC was compared. The effect of variation of NOM molecular weight on adsorption of 2-MIB in virgin AC and reactivated AC were also evaluated. BET surface area was decreased by 13 to 23% and total pore volume was decreased by 18 to 21% due to first and second reactivation compare to the virgin carbon. However, mesopore volume ($V_{meso}$) was increased about 14% after reactivation. It showed that micropore volume was decreased and move to mesopore or macropore after reactivation. Decreased adsorption capacity of 2-MIB was greatly related to below 3000Da. Adsorption capacity of 2-MIB was rather greater in virgin AC than in reactivated, which is strongly related to micropore volume.

• Corrosion Science and Technology
• /
• v.2 no.2
• /
• pp.59-67
• /
• 2003

Electrochemical potentiokinetic reactivation (EPR) tests are used to evaluate the degree of sensitization (DOS) of stainless steels and nickel base alloys. The validity of EPR test to detect DOS of these alloys, however, depends all the electrolyte composition employed. The existence of precipitates such as NbC, and TiC, etc. in the alloys also affects the reactivation behaviors of these alloys. In this investigation, the reactions involved during EPR processes are analyzed. In 0.5 M $H_2SO_4$+ 0.01 M KSCN electrolyte, a reactivation peak associated with the localized attack around NbC, different from that of intergranular corrosion, is observed for the solution annealed 347 SS. For solution annealed Alloy 600, matrix corrosion and localized attack around TiC with distinct anodic peaks appeared in the EPR curves are seen in the $H_2SO_4$+ KSCN electrolyte. With proper adjustment of elect rolyte composition, the contribution from intergranular corrosion, as a result of chromium carbide precipitation along the grain boundaries, can be distingui shed from the matrix and localized corrosion for the sensitized Alloy 600.