Toxicological Research
- Volume 4 Issue 1
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- Pages.47-53
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- 1988
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- 1976-8257(pISSN)
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- 2234-2753(eISSN)
Effect of Cholera Toxin, Dibutyryl cAMP and Adenosine on the In Vitro Reactivation of Latent Herpes Simplex Virus
- Cheong, D.K. (Section of Oral Biology, University of California) ;
- Park, N.H. (Section of Oral Biology, University of California)
- Published : 1988.06.01
Abstract
Cholera toxin and dibutyryl cyclic adenosine 3', 5'-monophosphate(db-cAMP) increased the rate and number of infections units produced in the in vitro reactivation of latent herpes simplex virus, whereas adenosine diminished them. cAMP concentration in latently infected trigeminal ganglia of mice was greatly increased by cholera toxin but was not affected by adenosine.