• Journal of Korean Society of Transportation
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• v.29 no.1
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• pp.81-93
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• 2011

This research deals with the multi-modal continuous network design problem to resolve the transportation policy problems for constructing and operating transportation facilities with considering the mutual decision-making process between transportation operator and user in the multi-modal network. Particularly, in the consideration of changes in travel pattern between transport modes due to the changes in transportation policy, road network for passenger car and transit network for public transportation are considered together. In the development of network design model, more rational Stackelberg equilibrium(cooperative game) rather than more general Nash equilibrium(non-cooperative game) approach is used and sensitivity analysis considering transport mode is used. A multi-modal continuous network design model in this study is developed for the arbitrary continuous network design parameters(${\epsilon},\hat{\epsilon},p$) of transportation policy decisions. As examples of application and evaluation for these design parameters, the developed model is applied to calculate 1)the optimal capacity of road link in the road transport policy, 2)the optimal frequency of transit line in public transport policy and 3)the optimal modal split in transport modal share policy.

• Journal of Society of Preventive Korean Medicine
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• v.21 no.3
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• pp.1-10
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• 2017

Objectives : The purpose of this study is to investigate the practice patterns of traditional Korean medicine (TKM) doctors and the acceptance of payment model in order to develop a new TKM health insurance payment model linked with TKM clinical practice guidelines (CPGs). Methods : Lumbar herniated intervertebral disc (HIVD) and idiopathic facial palsy (IFP) were selected as a test diseases to develop a new TKM payment model. The level of benefit coverage in the National Health Insurance (NHI) was designed. The survey asked 228 TKM doctors about their practice patterns in HIVD and IFP patients and acceptance of new payment model. Results : Mean of medical cost for treatment of HIVD was 441,000 KW, mean of treatment period ranged from 4.9 to 17.5 weeks, and mean of number of treatment ranged from 14.6 to 50.4 HIVD patients. In the case of IFP, mean of medical cost for treatment of IFP was 468,000 KW, mean of treatment period was at least 4.2 and up to 15.9 weeks and mean of number of treatment ranged from 14.2 to 52 IFP patients. Conclusions : Current study suggests that mixed payment model of per-visit and episode-based model seem to be proper. The model 1 bundles both items which were covered and not covered by NHI in a rational way. The model 2 is based on the development and application of critical pathway. Lastly, model 3 suggests bundling of items covered by current NHI. Acceptance of TKM doctors is expected to be highest in the model 3.

• Korean Journal of Veterinary Research
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• v.34 no.2
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• pp.307-313
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• 1994

We have previously shown that crude water extract of Euonymus alatus (EA) had strong prophylactic effect against chemically induced-and tumor cell implanted-cancer, and that the mechanisms responsible for its antitumor effects were due to nonspecific enhancement of the NK cell activities and the cell mediated immunity. However, it was unknown that any components of crude extract did work so, since it consisted of several components. In this paper, we fractionated the crude watar EA-extract into several fraction such as hexane-, ethylether-, ethyl acetate-, n-butanol- and water soluble-fraction, and screened the immune regulating activities of each fraction by the evaluation of lymphokine production and activated lymphocyte proliferation. As a result of the component fraction of EA-extract, it was found that n-butanol fraction was a potent immunostimulator, and the remained water soluble fraction also contained some stimulator, But, other fraction did not showed any remarkable effect. It is therefore suggested that EA-glycosides in n-butanol fraction may be new one of the potent biological response modifiers. The present study was also undertaken in an efforts to investigate the effects of elm-bark(EB, Ulmus clavidiana var japonica), which has been used for curing ulcer and inflammation as a folk medicine without any kind of experimental evidence to support this, on the cellular- and humoral-immune responses, lymphocyte function and NK cell activities in mice. Regardless of time and duration of EB-treatment, Arthus reaction and antibody response to SRBC were not modified by EB, but delayed hypersensitivity to SRBC was significantly enhanced only when EB was treated prior to SRBC-sensitization. EB slightly inhibited the proliferation responses of splenocytes to PHA-stimulation, but it significantly augmented the responses of these cells to S aureus Cowan 1 and Con A-activation, and these effects were manifested only when EB was added at culture initiation. EB did not influence Ig secretion of spleen cells but it significantly augmented the Con A-induced 1L 2 and MIF production of splenocytes. NK cell activities of splenocytes were markedly riled when effector cells were pretreated with EB and this augmentation was dine to the increase of binding affinity of effector cells to target cells and the target cell lytic activities of effector cells. These results led to the conclusion that EB triggers increase of cellular immune responses, such as delayed hypersensitivitiy, lymphokine production and NK cell activities. Also these results suggested that EB contains potent immune stimulants, which may provide the rational basis for their therapeutic use as one of the new biological response modifiers.

• Journal of Korea Water Resources Association
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• v.43 no.11
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• pp.967-976
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• 2010

AFDA (Approximate Full Distribution Approach) model of FORM (First-Order Reliability Model) which can quantitatively calculate the probability that storm sewer reach to performance limit state was developed in this study. It was defined as a failure if amount of inflow exceed the capacity of storm sewer. Manning's equation and rational equation were used to determine the capacity and inflow of reliability function. Furthermore, statistical characteristics and distribution for the random variables were analyzed as a reliability analysis. It was found that the statistical distribution for annual maximum rainfall intensity of 10 cities in Korea is matched well with Gumbel distribution. Reliability model developed in this study was applied to Y shaped storm sewer system to calculate the probability that storm sewer may exceed the performance limit state. Probability of failure according to diameter was calculated using Manning's equation. Especially, probability of failure of storm sewer in Mungyeong and Daejeon was calculated using rainfall intensity of 50-year return period. It was found that probability of failure can be significantly increased if diameter is decreased below the original diameter. Therefore, cleaning the debris in sewer pipes to maintain the original pipe diameter should be one of the best ways to reduce the probability of failure of storm sewer. In sewer system, two sewer pipes can flow into one sewer pipe. For this case, probability of system failure was calculated using multiple failure mode. Reliability model developed in this study can be applied to design, maintenance, management, and control of storm sewer system.

• Land and Housing Review
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• v.3 no.4
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• pp.307-314
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• 2012

This paper examines the characteristics and status of the major development policies for under-developed region by ministries and studies how the awareness or perspective of public officials on such policies impact the policy environment. This paper aims to redefine the goal and strategy of regional development policy so that it can effectively contribute to enhancing the quality of life of residents and improving competitiveness of the region. The problems and improvement direction found out through a documentational and practical research on the development policy for underdeveloped region can be summarized as follows: Firstly, more streamlined and integrated policies which are currently fragmented being implemented by different ministries are needed to enhance the effectiveness of policy execution. Secondly, improvements on the process of securing government funding and operating systems are needed to guarantee the rational standard of providing state subvention, the expansion of comprehensive subsidy and the independence of policy execution. Thirdly, amendments on the policy measures are needed to support the development and execution of the customized projects, strengthen cooperation among those projects by establishing a system for effective regional development project.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.5
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• pp.845-853
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• 2017

The main reason for urban traffic problems is the increasing in the use of private cars. In order to solve this problem, strong traffic demand management policies such as the collection of congestion tolls and the crackdown on freight vehicles are emerging. Now, however, it is necessary to seek ways for users to make changes in traffic behavior through direct communication between public agencies and passenger car users. As a technique to make this possible, mobility management, which aims to use rational passenger cars by inducing behavior change through individual consciousness change, has recently been proved to be effective in overseas. Therefore, this study concluded that the introduction of MM, which emphasizes individual voluntary behavior change, is necessary at present. In order to investigate the ways of inducing voluntary changes in traffic behavior of passenger car users, a questionnaire survey was conducted on traffic experts and the priorities of voluntary traffic behavior change measures were calculated using AHP. As a result of the analysis, it was shown that "to actively appeal to change the traffic behavior by using the mass media" was the top priority. The next priority were in order of company education for the change of traffic behavior, education for the school, and small-scale workshops.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.246-246
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• 2012

Smart catalyst design though novel catalyst preparation methods can improve catalytic activity of transition metals on reducible oxide supports such as titania by enhancement of metal oxide interface effects. In this work, we investigated Pt nanoparticles/titania catalysts under CO oxidation reaction by using novel preparation methods in order to enhance its catalytic activity by optimizing metal oxide interface. Arc plasma deposition (APD) and metal impregnation techniques are employed to achieve Pt metal deposition on titania supports which are prepared by multi-target sputtering and Sol-gel techniques. In order to tailor metal-support interface for catalytic CO oxidation reaction, Pt nanoparticles and thin films are deposited in varying surface coverages on sputtered titania films using APD. To assess the role of oxide support at the interface, APD-Pt is deposited on sputtered and Sol-gel prepared titania films. Lastly, characteristics of APD-Pt process are compared with Pt impregnation technique. Our results show that activity of Pt nanoparticles is improved when supported over Sol-Gel prepared titania than sputtered titania film. It is suggested that this enhanced activity can be partly ascribed to a very rough titania surface with the higher free metal surface area and higher number of sites at the interface between the metal and the support. Also, APD-Pt shows superior catalytic activity under CO oxidation as compared to Pt impregnation on sputtered titania support. XPS results show that bulk oxide is formed on Pt when deposited through impregnation and has higher proportion of oxidized Pt in the form of $Pt^{2+/4+}$ oxidation states than Pt metal. APD-Pt shows, however, mild oxidation with large proportion of active Pt metal. APD-Pt also shows trend of increasing CO oxidation activity with number of shots. The activity continues to increase with surface coverage beyond 100%, thus suggesting a very rough and porous Pt films with higher active surface metal sites due to an increased surface area available for the reactant CO and $O_2$ molecules. The results suggest a novel approach for systematic investigation into metal oxide interface by rational catalysts design which can be extended to other metal-support systems in the future.

• Journal of Biosystems Engineering
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• v.29 no.3
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• pp.267-274
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• 2004

Using geo-statistical method, yield data of different fields were analyzed to examine their field variability according to examining year, analysis method. Semivariogram and Kriged maps of geo-statistical analysis were used to examine their spatial dependence within a filed. The results obtained were as follows. 1) Descriptive statistical results of the yield showed that the yield and the difference of yield ranged from 100 to 946kg/10a and from 272 to 653kg/10a, respectively within a field. The coefficient of variation also ranged from 5.9 to 22.4 %. 2) More than 90% of yield data were placed between 350 to 850kg/10a. e results indicated that the gram mass flow sensor should have the measuring range from 0.34 to 0.82kg/s considering the yields when 4 rows head-feeding combine with 0.8 m/s of working speed was utilized. 3) A high spatial dependence was found within paddy field. The Q values ranged from 0.20 to 0.97, and the range of spatial dependence was from 6.9 to 53.3m. From this result, the rational sampling interval for yield investigation was estimated 6.9m. 4) Yields within a field between observation years showed considerable variability even if the field was evenly cultivated and managed. To apply precision agriculture in a paddy field, the field test should be continued to build a solid data-base including meteorological data, blight damage and insect damage.

• The Korean Journal of Pain
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• v.12 no.1
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• pp.27-35
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• 1999

Background: Fibromyalgia is a common syndrome of musculoskeletal pain and fatigue. Lacking distinctive histological or laboratory abnormality in diagnosis, it has often been considered a form of "psychogenic rheumatism". Fibromyalgia causes much distress to the affected patients and often frustrates physicians, who are unable to start rational therapy on any logical disease pathology. Methods: Growth hormone is essential for muscular homeostasis. In the present study, the notion that the stage-4 sleep anomaly typically seen in the fibromyalgia syndrome may disrupt growth hormone secretion was tested. Because growth hormone has a very short half-life, serum levels of somatomedin C were measured; somatomedin C is the major mediator of growth hormone's anabolic actions and is a prerequisite for normal muscle homeostasis. Serum levels of somatomedin C using acid-extraction procedure and two-site immunoradiome-tric assay (IRMA) and number of tender points were measured in 27 female patients with fibromyalgia from 40 to 60 years old and 27 healthy controls. Results: There were no differences in the concentration of somatomedin C between fibromyalgia patients and controls ($mean{\pm}SD$: $178.3{\pm}75.5$ ng/ml versus $166.3{\pm}76.6$ ng/ml; p=0.55). And there were no correlations between number of tender point and serum somatomedin C level by linear regression analysis. Conclusions: These findings did not support that there is a distinctive disruption of the growth hormone-somatomedin C neuroendocrine axis in a fibromyalgia syndrome. But we can not discard the hypothesis that disturbed sleep predispose to muscle pain.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.19 no.6
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• pp.533-546
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• 2007

This paper studied the design VE (Value Engineering) process among the various methods to satisfy the requirement of user and cost saving in the overall redesign process for the Turn-key base construction project. This study has been estabilished the rational and practical analysis process with the stepwise by using the design VE process. The efficiency and safety were verified with the adoptian of computer simulation to cope with the problem of initial analysis and verification for design VE process in the large construction project. In the previous design VE process, there is a limitation for the analysis of design VE in the planing stage and the execution time period of the large construction project. The previous application of VE technique was only for the construction of harbor facilities, so there was no contribution of cost saving in the function and construction. However, this paper proposed the selection methodology of VE items and hence the redesign VE process can be efficiently improved. It can be also improved the process of functional analysis rationally and practically. About 4.6 billion won has been saved with applying to the harbor construction project with using the VE method proposed in this paper. The study gives the direction of VE to be accomplished efficiently in the similar project.