• 대한후두음성언어의학회지
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• 제5권1호
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• pp.38-43
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• 1994

Though normal vocal cords show regular vibration, pathologic vocal cords show irregularity between peaks. Jitter means fluctuation in the time interval between peaks, and Shimmer means cycle to cycle variation in the amplitude of the peaks. We investigated the vocal vibration of Korean normal persons objectively. The fundamental frequency, Jitter, Shimmer and SNR(signal to noise ratio) of normal persons were compared with that of vocal Polyp Patients with CSpeech Program for the possibility of distinguishing the pathologic vocal vibration from normal. The results were as follows ; Comparing the fundamental frequency of vocal Polyp Patients with normal persons, great change was noted only in female cases. But the Jitter and Shimmer of vocal polyp patients were greater than normal significantly in both male and female cases. SNR was lower than normal in vocal polyp patients. In the conclusion, fundamental frequency, Jitter, Shimmer and SNR might be meaningful parameters distinguisuing pathologic vibration from normal.

• Communications for Statistical Applications and Methods
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• 제6권2호
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• pp.511-522
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• 1999

The paper considers the problem of robustness in hierarchical bayesian models. In specific we address Bayesian robustness in the estimation of normal means. We provide the ranges of the posterior means under $\varepsilon$-contamination class as well as the density ratio class of priors. For the class of priors that are uniform over a specified interval we investigate the sensitivity as to the choice of the intervals. The methods are illustrated using the famous baseball data of Efron and Morris(1975).

• 한국정밀공학회지
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• 제13권11호
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• pp.92-99
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• 1996

The contact pressure in jointed plates was measured by means of an improved ultrasonic technique. In order to get calibration curve, the relationship between contact pressure and ratio of boundary and bottom echo of normal beam probes were obtained for the calibration blocks with various surface roughness. The ratio of boundary and bottom echoes were measured for the upper/under plates locally compressed with uniform pressure, and the distribution of contact pressure was obtaines. The measured pressure has a good agreement with results of FEM analysis. Thus the proposed ultrasonic method in this work is very useful to measure the contact pressure.

• 한국데이터정보과학회:학술대회논문집
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• 한국데이터정보과학회 2005년도 추계학술대회
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• pp.71-84
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• 2005

The Fieller-Creasy problem involves statistical inference about the ratio of two independent normal means. It is difficult problem from either a frequentist or a likelihood perspective. As an alternatives, a Bayesian analysis with noninformative priors may provide a solution to this problem. In this paper, we extend the results of Yin and Ghosh (2001) to unbalanced sample case. We find various noninformative priors such as first and second order matching priors, reference and Jeffreys' priors. The posterior propriety under the proposed noninformative priors will be given. Using real data, we provide illustrative examples. Through simulation study, we compute the frequentist coverage probabilities for probability matching and reference priors. Some simulation results will be given.

• Journal of the Korean Statistical Society
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• 제18권1호
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• pp.26-37
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• 1989

When we select the t best out of k populations in the indifference zone formulation, a lower confidence bound on the probability of a correct selection is derived for families with monotone likelihood ratio. The result is applied to the normal means problem when the variance is common, and to the normal variances problem. Tables to implement the confidence bound for the normal variances problem are provided.

• Radiation Oncology Journal
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• 제36권3호
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• pp.172-181
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• 2018

Successful anticancer strategies require a differential response between tumor and normal tissue (i.e., a therapeutic ratio). In fact, improving the effectiveness of a cancer therapeutic is of no clinical value in the absence of a significant increase in the differential response between tumor and normal tissue. Although radiation dose escalation with the use of intensity modulated radiation therapy has permitted the maximum tolerable dose for most locally advanced cancers, improvements in tumor control without damaging normal adjacent tissues are needed. As a means of increasing the therapeutic ratio, several new approaches are under development. Drugs targeting signal transduction pathways in cancer progression and more recently, immunotherapeutics targeting specific immune cell subsets have entered the clinic with promising early results. Radiobiological research is underway to address pressing questions as to the dose per fraction, irradiated tumor volume and time sequence of the drug administration. To exploit these exciting novel strategies, a better understanding is needed of the cellular and molecular pathways responsible for both cancer and normal tissue and organ response, including the role of radiation-induced accelerated senescence. This review will highlight the current understanding of promising biologically targeted therapies to enhance the radiation therapeutic ratio.

• The Journal of Korean Physical Therapy
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• 제18권3호
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• pp.1-7
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• 2006

Purpose: This study was performed to determine the difference or temporal-spatial gait asymmetry ratio according to static pelvic inclination level in hemiplegic patients. Methods: The subjects were 25 hemiplegic patients who was experienced stroke on MCA territory. Gait parameters and static pelvic inclination were recorded by $GAITRite^{(R)}$ system and radiologic PACS. The subjects were divided into three group according to static pelvic inclination. In the group I, the subjects have static pelvic inclination below $58^{\circ}$. The group II has $58^{\circ}{\sim}62^{\circ}$ or static pelvic inclination and the group m has over $62^{\circ}$ or static pelvic inclination. The data or three groups were analysed with ANOVA. Results: In comparison or single support time asymmetry ratio among 3 groups, the score or group II was significantly higher than the other groups(p<0.05). But the swing time asymmetry ratio was not significant(p>0.05). Conclusion: Asymmetry ratio of single support time was statistically significant by static pelvic inclination level. But asymmetry ratio or group II was the highest among three groups. It means that the patients or normal range of pelvic inclination was showed the most asymmetry or gait. And swing time asymmetry ratio was not significant among three groups. Even if the patient has normal ranged static pelvic inclination, it doesn't suggest that the patient has low gait asymmetry.

• 대한핵의학회지
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• 제16권2호
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• pp.25-28
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• 1982

Estimation of liver size is essential in the diagnosis of liver disease, Many approaches have been attempted in evaluation of liver size such as the measurement of length, area and volume. Among these, area and volume measurements are accurate but complicated, so we commonly use formerly introduced various linear measurements, but in scintigraphy one must calculate the actual liver size using rate of reduction, which is time consuming. Because of these reasons, we carried out present study to represent liver size by means of a simple liver measurement like we express the cardiac size by cardiothoracic ratio. Our cases consisted of 100 clinically normal subjects as the normal group and 50 patients suffering from liver disease and diagnosed to have hepatomegaly on abdominal palpation and scintigram at Dept, of Radiology of St. Mary's Hospital, Catholic Medical College during the period of 8 months from Jan. 1980. We measured the liver size using 4 linear diameters(Fig. 1). And as the reference measurement, the distance from the right margin of the liver to the left margin of the spleen was measured. We called this "abdominal transverse diameter(ATD)". The results were as follows; 1) The smallest value was recorded in the midline vertical diameter (MVD). It was $4.2{\pm}0.4cm$ in normal group and $5.0{\pm}0.6cm$ in the hepatomegaly group. 2) The diameter using other methods ranged from 5.6 to 7.2 cm in the normal group and from 6.3 to 7.5cm in the hepatomegaly group. 3) There was significant difference in the ratio of each diameter to ATD between the normal and hepatomegaly group (<0.01). We called this "hepato-abdominal ratio". 4) The "hepato-abdominal ratio" using MVD is $0.43{\pm}0.06$ in the normal group and $0.53{\pm}0.07$ in the hepatomegaly group. The "hepato-abdominal ratio" of MVD was most significantly different between normal and hepatomegaly group. 5) The tolerance limits(99%) of "hepato-abdominal ratio" using MVD is from 0.41 to 0.45 in the normal group and from 0.51 to 0.55 in the hepatomegaly group. Therefore, by reasons of error during measurement and convenience of memory, it was warranted to suggest hepatomegaly when "hepato-abdominal ratio" using MVD is more than 0.5 in the interpretation of hepatic scintigram.

• 말소리와 음성과학
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• 제5권3호
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• pp.55-60
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• 2013

The purpose of this study was to investigate the acoustic characteristics of crying infants according to the communication intents such as hunger and pain in terms of acoustic differences in the fundamental frequency ($F_0$), jitter, shimmer, noise-to-harmonic ratio(NHR), habitual pitch, and intensity. The subjects were 20 healthy, normal infants, less than seven days old, from the city of Seoul and were born after 38 to 42 weeks(full term) of pregnancy. The sound of crying was recorded for three minutes. The crying due to pain was induced by means of the inborn metabolism error test, whereas the crying due to hunger was verified by means of the rooting reflex by waiting for the designated eating time. The results were as follows: (1) the fundamental frequency, noise-to-harmonic ratio(NHR), and intensity of the infants' crying due to pain was higher than that by hunger, showing a significant difference between the mean values. (2) the infants' crying due to hunger and that by pain did not have a significant difference in the mean jitter and shimmer values but both of them were largely outside of the normal threshold values(jitter by 1.04% and shimmer by 3.81%). This study was significant in the sense that it showed the acoustic characteristics of infants' crying from hunger and pain were very different from each other according to the communication intents in terms of the six acoustic parameters.

• 대한치과보철학회지
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• 제33권3호
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• pp.467-491
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• 1995

In order to analyze the occlusin of intercuspation with maximun bite force, fifteen healthy adult subjects with the ages 23 to 27 were studied(Group1 ; 5-normal occlusion with Angle's Class1, Group2 ; 5-Angle's Class2 malocclusion, Group3 ; 5-Angle’s Class3 malocclusion). Head Position was fixed with occlusal plane paralleling to horizontal line and occlusal registration r cord was made with polyether rubber impression material(Ramitec, ESPECo. West Germany). After all subject were trained for maximum intercuspation at least 5 times, occlusal registration procedure was repeated for this study. Lower posterior rubber occlusal registration records were sliced with 1mm thickness using precision metal sliding channel(Hitachi Ind. Co., Japan). Gross sectional drawings were traced from occluding view of upper and lower posterior teeth on the rubber slices using digitizer, and superimposed for the determination of each drawing distance(Superimposed Rubber Pattern Method). Based on superimposed rubber pattern drawings, total area of occlusal view, sum of each area of the 5 divided occlusal contact provinces and its ratio, total area and number of occlusal contact area were determined to elucidate occlusal stability in the normal and abnormal occlusion groups. The data were analysed by t-test(p=0.05) to determine statistical significance. The obtained results were as follows : 1. Group1 showed the largest standard area with occlusal view of the lower posterior teeth and Group3 showed the smallest area. There was a significant difference between Group2 and Group3(p=0.025), and Gropu1 was not statistically different for both Group2 and Group3. 2. Means and ratio of the under 2.0mm area(D) and ratio showed $197.49mm^2$, 59.76% in Group1, $188,69mm^2$, 56.10% in Group2, and $174.23mm^2$, 55.76% in Group3. The results that Group1 has the most area/ratio and Group3 has the least area/ratio can be considered Group1 is the most advantageous for masticatory effective area, and Group3 is the least adnantageous. 3. Means and ratio of the under 1.0mm area(C) were $198.96mm^2$, 42.65% in Group1, 123.06$mm^2$, 46.58% in Group2, and $92.24mm^2$, 29.52% in Group3. These data means that Group1 is the most advantageous in terms of masticatory effective area and Group3 is the least. 4. Means and ratio of the under 0.5mm area(B) were $86.68mm^2$, 26.68% in Group1, $62.98mm^2$, 18.71% in Group2, and $36.44mm^2$, 11.66% in Group3. These can also be considered Group1 is the most advantageous for masticatory effective area and occlusal stability. 5. Means and ratio of the under 0.05mm area(A) were $30.92mm^2$, 9.21% in Group1, $14.31mm^2$, 4.25% in Group2, and $7.59mm^2$, 2.43% in Group3. The area ratio of the each subject group was(4.1) : (1.9) : (1)and the data of the under 0.05mm area has the intimate relationship with inter-group and intra-group data/ratio. 6. First molar showed the most occlusal contact points in all subject group and Group1 showed somewhat uniformly distributed occlusal contact point except first premolar. In Group2, all contact point in posterior teeth showed significantly reduced distribution except first molar. Group3 showed evenly distributed contace points in first and second molars.