• Title/Summary/Keyword: Rate function

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Influence of Intracerebroventricular Thiopental Sodium on the Renal Function in Conscious Rabbit (측뇌실내로 투여한 Thiopental Sodium의 가토 신장기능에 미치는 영향)

  • Hong, Ki B.;Cho, Kyung W.
    • The Korean Journal of Physiology
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    • v.19 no.1
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    • pp.35-48
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    • 1985
  • One of most frequently used anesthetic agents is barbiturate derivatives. Pentobarbital or thiopental sodium have been used most frequently in the laboratory or clinical practice. There have been reports on the renal effects of barbiturate anesthesia in human and laboartory animals. Renal effects of thiopental sodium anesthesia, however, are still controversial. One of the discrepancies may be derived from the doses used. It has been reported that subanesthetic small dose of thiopental sodium influences the renal function directly. To clarify possible central effects of very small amounts of thiopental sodium on the renal function, experiments have been done in conscious rabbits. Thiopental sodium was infused into the lateral cerebroventricle for 10 minutes. Intracerebroventricular thiopental sodium induced increased urinary volume, glomerular filtration rate and renal plasma flow by doses of $0.1{\sim}1.0\;mg/10 min/rabbit$. Filtration fractions were not changed. Sodium, chloride and potassium excretions were increased by 0.065 mg/10 min/rabbit of thiopental sodium without significant changes of renal hemodynamics. Higher doses of thiopental sodium $(0.1{\sim}1.0\;mg/10 min/rabbit)$ induced greater increases of electrolytes excretion and renal hemodynamics. Free water clearance was not changed by thiopental sodium, but the fractional excretion of free water showed a tendency of decrease. Fractional excretion of sodium was increased by doses of 0.065 to 1.0 mg of thiopental sodium . Highly significant correlation between the changes of glomerular filtration rate and the changes of sodium excretion were found in the higher doses. Plasma renin concentration (activity) was not changed by the centrally administered thiopental sodium. Intravenous thiopental sodium, 1.0 mg/rabbit, induced no changes of renal function in conscious rabbit. These data suggest that intracerebroyentricular thiopental sodium can increase urinary sodium excretion directly by inhibition of sodium reabsorption in the renal tubules and/or indirectly by increasing the renal hemodynamics.

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Effects of the Probody Massage on the Physical Characteristics, Gross Motor Function and ROM in Youth with Cerebral Palsy : Case study (프로바디마사지가 뇌병변 장애우의 신체적 특성과 대동작 기능 및 관절 가동범위에 미치는 영향 : 사례연구)

  • Kim, Eui-Suk;Yang, Jeong-Ok;Lee, Joong-Sook
    • Korean Journal of Applied Biomechanics
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    • v.25 no.4
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    • pp.453-463
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    • 2015
  • Objective : The purpose of this study was to investigate the effects of the Probody Massage Program on the physical characteristics, gross motor function and ROM (Range Of Motion) of children with cerebral palsy. Method : The subjects of this study were two children who have been diagnosed with first grade cerebral palsy that utilized T development support center located in B Metropolitan city for 8 weeks, twice a week, to carry out the Probody Massage Program for 30 minutes. Physiological reactions (height, weight, BMI, blood pressure (an index of inflammation), pulse rate) and large operating functions (sitting, crawling and the joints' range of motion as an angle of the shoulders' upper limb articulation) were measured pretest, after 4 weeks, and after 8 weeks. Results : The Probody Massage Program showed positive changes in physical characteristics (blood pressure, sitting, and crawling), gross motor function (upper limb shoulder movement), joint range of motion, height, body weight, metabolic activation and blood circulation of children with cerebral palsy. Conclusion : We believe making a practical impact on the growth and development, functional recovery of daily life, and improvement of quality of life of children with cerebral palsy by utilizing Probody Massage Program improves blood pressure (an index of inflammation), pulse, sitting, crawling, and the joints' range of motion as an angle of the shoulder joints' upper limb movement of children with cerebral palsy.

An image enhancement Method for extracting multi-license plate region

  • Yun, Jong-Ho;Choi, Myung-Ryul;Lee, Sang-Sun
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.6
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    • pp.3188-3207
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    • 2017
  • In this paper, we propose an image enhancement algorithm to improve license plate extraction rate in various environments (Day Street, Night Street, Underground parking lot, etc.). The proposed algorithm is composed of image enhancement algorithm and license plate extraction algorithm. The image enhancement method can improve an image quality of the degraded image, which utilizes a histogram information and overall gray level distribution of an image. The proposed algorithm employs an interpolated probability distribution value (PDV) in order to control a sudden change in image brightness. Probability distribution value can be calculated using cumulative distribution function (CDF) and probability density function (PDF) of the captured image, whose values are achieved by brightness distribution of the captured image. Also, by adjusting the image enhancement factor of each part region based on image pixel information, it provides a function that can adjust the gradation of the image in more details. This processed gray image is converted into a binary image, which fuses narrow breaks and long thin gulfs, eliminates small holes, and fills gaps in the contour by using morphology operations. Then license plate region is detected based on aspect ratio and license plate size of the bound box drawn on connected license plate areas. The images have been captured by using a video camera or a personal image recorder installed in front of the cars. The captured images have included several license plates on multilane roads. Simulation has been executed using OpenCV and MATLAB. The results show that the extraction success rate is more improved than the conventional algorithms.

Relationship of Renal Echogenicity with Renal Pathology and Function

  • Lee, Jin Hee;Cho, Myung Hyun;Chung, Sung Ill;Lim, So Dug;Kim, Kyo Sun
    • Childhood Kidney Diseases
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    • v.21 no.2
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    • pp.47-52
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    • 2017
  • Purpose: Renal ultrasonography has been widely used in children with renal disease. However, the relationship of renal echogenicity with renal pathology and function in children is not well known. Method: Ultrasound examination was performed in 75 patients undergoing renal biopsy for suspected renal disease in Konkuk University Medical Center from August 2005 to November 2015. We compared renal echogenicity to pathologic findings and renal function. Renal echogenicity was scored as 0 to 2 by comparing adjacent liver echogenicity. Three histologic characteristics were evaluated: glomerular changes, interstitial infiltration or fibrosis, and tubular atrophy. These were graded as 0 to 3, according to increasing severity. Laboratory results included urine albumin excretion and estimated glomerular filtration rate (eGFR). Results: Among pathologic findings, renal echogenicity revealed a positive correlation with interstitial infiltration or fibrosis (r=0.259, P=0.025), and with tubular atrophy (r=0.268, P=0.02). Renal echogenicity and glomerular changes were not correlated. Renal echogenicity showed a positive correlation with microalbuminuria (r=0.283, P=0.014), but a negative correlation with eGFR (r=-0.352, P=0.002). Conclusion: Increased renal echogenicity suggested severe interstitial infiltration or fibrosis and tubular atrophy among the pathologic findings. Moreover, increased echogenicity is correlated with increased urine albumin excretion and decreased eGFR. Echogenicity on ultrasonography is useful for determining the status of renal pathology and function.

Effects of Scolopendra subspinipes multilans Herb-Acupuncture on the Carrageenan induced arthritis in rats (오공약침(蜈蚣藥針)이 Carrageenan으로 유발(誘發)된 흰 쥐의 관절염(關節炎)에 미치는 영향(影響))

  • Yu, Won-Bok;Soh, Kyeong-Sun;Jeong, Chan-Gil;Kim, Kwang-Ho
    • Journal of Pharmacopuncture
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    • v.7 no.3
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    • pp.89-98
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    • 2004
  • This study was designed to check of Scolopendra subspinipes multilans Herb-Acupucture on effect of anti-inflammtory function, anti-febrile function and analgestic function in carrageenan-induced arthritic rat. Each of 8 rat were classified into control, sample group. Control group were inject by normal saline and Sample group were injected by Scolopendra subspinipes multilans. Herb-Acupuncture. After elicitating edema and inflammation of Sprgue Dawely(SD) rats by injection of 1% Carrageenan 0.1ml, then the rate of increase of paw edema, CRP, ESR, WBC were checked and rectal-temperature, topical temperature was checked about anti-febrile. writhing syndrome was checked about analgesic. The results were as follows 1. In the sample group, the rate of increase of paw edema was significantly decreased as compared with thatof control group(P<0.05) 2. In the sample group, the rectal-temperature was non-significantly decreased as compared with that of control group (P<0.05) 3. In the sample group, CRP and WBC was significantly decreased as compared with that of control group, but ESR was not.(P<0.05) 4. In the sample group, opical-temperature was significantly decreased as compared with that of control group (P<0.05) 5. In the sample group, analgestic function was not sigiflcntly effected as compared with that of control group(P<0.05) According to the above result, it can be concluded Scolopendra subspinipes multilans Herb-Acupucture showed the treatment effects on the artifical arthritis resulted from carrageenan in rat and it is suggested that more interest and study in the mechanism and clinical use were needed.

Estimating the Tax Revenue Function of the Personal Incomes (개인소득세수함수(個人所得稅收函數) 추정(推定))

  • Roh, Kee-sung
    • KDI Journal of Economic Policy
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    • v.12 no.4
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    • pp.71-95
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    • 1990
  • The purpose of this paper is to estimate the revenue function of the personal income tax of Korea. Unlike the traditional approach employing the data adjustment, this paper explicitly includes the explanatory variables of the tax rate or schedule in the revenue function and further estimates the functions by income sources such as labor, interest, global, and dividend incomes. One of the main findings is the GNP elasticity of the combined personal income tax is around 1.2 when evaluated on the basis of the estimates of the GNP elasticities of tax revenue from respective income sources, which is somewhat smaller than those in the previous studies. Another interesting result is that the GNP and interest rate elasticities of the interest income, are found around one and .15 respectively, as expected. Also, the estimate of the tax-free income coefficient is significantly negative in the labor income tax revenue function.

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An Artificial Intelligence Game Agent Using CNN Based Records Learning and Reinforcement Learning (CNN 기반 기보학습 및 강화학습을 이용한 인공지능 게임 에이전트)

  • Jeon, Youngjin;Cho, Youngwan
    • Journal of IKEEE
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    • v.23 no.4
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    • pp.1187-1194
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    • 2019
  • This paper proposes a CNN architecture as value function network of an artificial intelligence Othello game agent and its learning scheme using reinforcement learning algorithm. We propose an approach to construct the value function network by using CNN to learn the records of professional players' real game and an approach to enhance the network parameter by learning from self-play using reinforcement learning algorithm. The performance of value function network CNN was compared with existing ANN by letting two agents using each network to play games each other. As a result, the winning rate of the CNN agent was 69.7% and 72.1% as black and white, respectively. In addition, as a result of applying the reinforcement learning, the performance of the agent was improved by showing 100% and 78% winning rate, respectively, compared with the network-based agent without the reinforcement learning.

Effects of a Rehabilitation Program on Quality of Life, Cardiopulmonary Function and Fatigue During Radiotherapy for Breast Cancer Patients (유방암 환자의 방사선 치료 기간 동안 재활치료 프로그램이 삶의 질, 심폐기능, 피로에 미치는 영향)

  • Do, Jung-Hwa;Seong, Jun-Hyuk;Ahn, Jun-Su;Cho, Young-Ki
    • Physical Therapy Korea
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    • v.19 no.1
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    • pp.56-65
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    • 2012
  • This study examines the effects of a rehabilitation program on quality of life (QOL), cardiopulmonary function and fatigue during radiotherapy for breast cancer patients. The program includes aerobic exercise, stretching and strengthening exercises. Sixty-five women participated in this study and they were asked to perform supervised exercises that last for 60 minutes five times a week for six weeks. The European organization for research and treatment of cancer-cancer (EORTC QLQ-C30) and the breast (EORTC QLQ-BR23), predicted maximal volume of oxygen consumption ($VO_{2max}$) and fatigue severity scale (FSS) were assessed before and after the rehabilitation program. The 60-minute program consisted of a 10-minute warm-up, 30-minute of aerobic exercises, and 15-minute of strengthening exercises, followed by a five-minute cool-down. Heart rates were monitored throughout the exercise class to ensure that patients were exercising at the target heart rate of 40~75% of the age-adjusted heart rate maximum. There were statistically significant differences in the changes of physical function and cancer related symptoms in the EORTC QLQ-C30 and EORTC QLQ-BR23 (p<.05). There was a statistically significant improvement in the predicted $VO_{2max}$ (p<.05), although there were no significant differences in the FSS (p>.05). The results of our study suggest that a supervised rehabilitation program may benefit the physical aspects and QOL of patients receiving radiotherapy for breast cancer.

The Petrov-Galerkin Natural Element Method : II. Linear Elastostatic Analysis (페트로프-갤러킨 자연요소법 : II. 선형 정탄성 해석)

  • Cho, Jin-Rae;Lee, Hong-Woo
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.18 no.2
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    • pp.113-121
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    • 2005
  • In order to resolve a common numerical integration inaccuracy of meshfree methods, we introduce an improved natural clement method called Petrov-Galerkin natural element method(PG-NEM). While Laplace basis function is being taken for the trial shape function, the test shape function in the present method is differently defined such that its support becomes a union of Delaunay triangles. This approach eliminates the inconsistency of tile support of integrand function with the regular integration domain, and which preserves both simplicity and accuracy in the numerical integration. In this paper, the validity of the PG-NEM is verified through the representative benchmark problems in 2-d linear elasticity. For the comparison, we also analyze the problems using the conventional Bubnov-Galerkin natural element method(BG-NEM) and constant strain finite clement method(CS-FEM). From the patch test and assessment on convergence rate, we can confirm the superiority of the proposed meshfree method.

Development of a Safety Performance Function for Expressway Tollgates (고속도로 영업소 구간 안전성능함수 개발)

  • Lee, Taehun;Kwak, Ho-Chan;Kim, Dong-Kyu;Kho, Seung-Young
    • Journal of Korean Society of Transportation
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    • v.33 no.1
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    • pp.81-89
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    • 2015
  • Crashes that occur at tollgates have different characteristics compared to those of the mainline on expressways in terms of crash cause, crash type, and vehicle type. Due to this fact, the safety performance function (SPF) focused on the expressway tollgates, apart from the mainline, should be developed. The aim of this study is, therefore, to identify the influential factors and develope a SPF for crashes at tollgates. Firstly, we established independent variables affecting crashes at tollgates through literature review and descriptive statistical analysis. Based on these variables, two negative binomial regression models with different form of independent variables were developed and goodness-of-fits of each model were compared. According to the results, the number of crashes increases i) as AADT, Hi-pass rate, and heavy vehicle rate increase, ii) as average lane width decreases, iii) on the mainline tollgate type. The safety performance function developed in this study could be applied to select hot-spots for expressway tollgates.