• 한국임상수의학회지
• /
• 제25권3호
• /
• pp.215-217
• /
• 2008

Medical records from the Veterinary Medical Teaching Hospital of the University of Missouri-Columbia from 2004 to 2007 were available for 28 raptors that underwent long bone fracture repair. There were 14 owls, 10 hawks, 2 vultures, 1 eagle, and 1 falcon. Mean body weight was 780 g (ranged from 150 to 1400 g) for 14 owls; 650 g (ranged from 150 to 1270 g) for 10 hawks; 1760 g (ranged from 1520 to 2000 g) for 2 vultures; 5000 g for 1 eagle; and 130 g for 1 falcon. Of all 28 fracture cases, 11 cases (39%) and 1 case (3%) were related to hit-by-car and shooting respectively. Physical examination revealed dehydration in 18 raptors (64%) and lethargy in 12 raptors (42%). Forty one long bone fractures were included in 28 cases. The radiographs revealed 13 ulnar fractures (32%), 12 humeral fractures (30%), 10 radial fractures (25%), 4 tibiotarsal fractures (9%), 1 femoral fracture (2%), and 1 fibular fracture (2%). External skeletal fixation using polymethylmethacrylate (PMMA) combined with intramedullary fixation was used in 19 long bone fractures (46%). Intramedullary fixation using intramedullary Kirschner pin was used in 16 long bone fractures (39%). No surgical treatment was performed in 6 long bone fractures (15%). This study reported that many of raptors presented dehydration and lethargy when admitted for treatment. Therefore, proper hydration and nutrition are critical pre-surgical requirements. In addition, combination of internal fixation and external skeletal fixation using PMMA might be better option to treat raptors with comminuted fracture that results from mostly trauma of hit-by-car.

• 한국환경생태학회지
• /
• 제25권1호
• /
• pp.81-90
• /
• 2011

한국의 서해안 지역에 위치한 새만금 지역은 만경강, 동진강 하구의 갯벌지역으로 수조류의 중요한 서식지 이다. 본 조사는 2008년 11월부터 2009년 2월까지 새만금에 도래하는 수조류 군집특성 파악을 위해 실시하였다. 월동기 동안 맹금류를 포함하여 새만금에서 관찰된 수조류는 69종, 최대개체수는 409,044개체이었다. 유사한 생태적 특징을 고려하여 분류군별로 나누어 보면 14개 분류군이 관찰되었다. 주요 우점종은 가창오리, 청둥오리, 쇠기러기, 검은머리흰죽지이었다. 쇠기러기는 조사시기에 따라 양의 상관관계를 보였다(rp=0.72, p<0.05). 주요 우점종 중 가창오리, 쇠기러기, 큰기러기, 검은머리흰죽지, 혹부리오리는 기존 연구와 비교했을 때 증가하였으며, 청둥오리, 흰뺨검둥오리, 민물도요는 큰 변화가 없었다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권15호
• /
• pp.6549-6556
• /
• 2015

The PI3K-Akt-mTOR, $Wnt/{\beta}$-catenin and apoptosis signaling pathways have been shown to be involved in genesis of colorectal cancer (CRC). The aim of this study was to elucidate whether combination of Gelam honey and ginger might have chemopreventive properties in HT29 colon cancer cells by modulating the mTOR, $Wnt/{\beta}$-catenin and apoptosis signaling pathways. Treatment with Gelam honey and ginger reduced the viability of the HT29 cells dose dependently with $IC_{50}$ values of 88 mg/ml and 2.15 mg/ml respectively, their while the combined treatment of 2 mg/ml of ginger with 31 mg/ml of Gelam honey inhibited growth of most HT29 cells. Gelam honey, ginger and combination induced apoptosis in a dose dependent manner with the combined treatment exhibiting the highest apoptosis rate. The combined treatment downregulated the gene expressions of Akt, mTOR, Raptor, Rictor, ${\beta}$-catenin, $Gsk3{\beta}$, Tcf4 and cyclin D1 while cytochrome C and caspase 3 genes were shown to be upregulated. In conclusion, the combination of Gelam honey and ginger may serve as a potential therapy in the treatment of colorectal cancer through inhibiton of mTOR, $Wnt/{\beta}$ catenin signaling pathways and induction of apoptosis pathway.

• 한국동물위생학회지
• /
• 제30권3호
• /
• pp.467-472
• /
• 2007

Eurasian black vulture (Aegypius monachus) belongs to family Accipitridae and is a raptor preying small birds and mammals. It is a wintering bird residing from the mid of November to the late of March in Korea. Although Eurasian black vulture population wintering at Korea is gradually increased, the efficient rescue and treatment for injured Eurasian black vultures are still problematic, due to lack of basic data. Therefore, in this survey, to obtain basic resources for establishing more efficient rescue system, we surveyed the number of Eurasian black vultures wintering at Gangwon province, wintering ecology and injury state of Eurasian black vulture. Survey area was Togyo reservoir at Cheorwon, Seonan basin at Yangoo and Wolsong reservoir at Chuncheon from November 2004 to March 2005. From 12 rescued Eurasian black vultures, physical examination, total plasma protein (TPP) and packed cell volume (PCV) were measured. To survey injury state of Eurasian black vultures wintering at Gangwon province, we surveyed the cause, morbidity and mortality from 103 Eurasian black vultures, based on medical records from animal rescue teams. The number of eurasian black vultures were gradually increased from November, peaked at Feburary, then steeply decreased at March. Eurasian black vultures showed the most vigorous activity around 1 PM within a day. In physical examination, mean body weight was $9.6{\pm}1.22kg$, body length was $1130{\pm}45.4mm$. No statistically significant difference in body weight and length between male and female eurasian black vultures was observed. Mean PCV was $40.2{\pm}2.7%$, while mean TPP was $5.86{\pm}0.8mg/dl$. The most common cause of injury and mortality was intoxication, while that of morbidity was fatigue.

• 컴퓨터교육학회논문지
• /
• 제22권1호
• /
• pp.47-61
• /
• 2019

SW 중심사회가 도래하면서 사회 모든 분야에서 SW 기반의 문제해결 역량이 강조되고 있다. 대학에서도 비전공자를 위한 SW 기초교육을 의무화하고 프로그래밍 교육을 진행하는 추세이다. 본 연구는 프로그래밍 언어의 설계 원칙 중 간결성과 일반성을 수용하는 문법요소를 도출하고 이를 기반으로 비주얼 프로그래밍 언어(스크래치, 앱인벤터)와 다이어그래밍 언어(랩터, 플로우고리즘)를 비교 분석하였다. 그 결과 간 결성과 일반성에 있어 랩터의 표현력과 효율성이 스크래치보다 우세한 것으로 분석되었으며 학습자의 결과물을 통해 이를 확인하였다. 본 연구를 통해 프로그래밍 언어의 특징에 기반한 프로그래밍 기초교육의 설계와 구현에 기여할 것으로 기대한다.

• 한국임상수의학회지
• /
• 제36권4호
• /
• pp.196-199
• /
• 2019

This study was conducted to evaluate and analyze fractures types, sites and surgical approach of wild birds in Korea. The study was conducted on data collected for fracture lesion sites, species, outcomes, surgical methods, treatments and medical records from wildlife centers in South Korea. All birds were subjected to clinical examination, followed by surgical invasion and post-operative care. Fractures were more common in adult non-raptor species (51.57%) as compared to raptors (48.43%). Of the 254 cases evaluated, maximum cases comprised ulnar fractures (29.70%), followed by radial (21.76%) and humeral fractures (17.35%). Treatment procedures at 340 fracture sites were maximally treated with figure-8 bandage (33.07%), external skeletal fixator-intramedullary pin (ESF+IM tie-in fixation) (20.86%), and other varied procedures. All birds were kept indoors till recovery. Treatment outcomes were dependent on the type of bone fractured and surgical method applied. Based on the surgical treatments and outcomes, birds were kept hospitalized, and released or euthanized. The findings of this study provide information for veterinarians regarding the fractures sites, basic database for the species and outcomes of fracture repair in wild birds.

• Molecules and Cells
• /
• 제45권9호
• /
• pp.660-672
• /
• 2022

The target of rapamycin complex (TORC) plays a key role in plant cell growth and survival by regulating the gene expression and metabolism according to environmental information. TORC activates transcription, mRNA translation, and anabolic processes under favorable conditions, thereby promoting plant growth and development. Tomato fruit ripening is a complex developmental process promoted by ethylene and specific transcription factors. TORC is known to modulate leaf senescence in tomato. In this study, we investigated the function of TORC in tomato fruit ripening using virus-induced gene silencing (VIGS) of the TORC genes, TOR, lethal with SEC13 protein 8 (LST8), and regulatory-associated protein of TOR (RAPTOR). Quantitative reverse transcription-polymerase chain reaction showed that the expression levels of tomato TORC genes were the highest in the orange stage during fruit development in Micro-Tom tomato. VIGS of these TORC genes using stage 2 tomato accelerated fruit ripening with premature orange/red coloring and decreased fruit growth, when control tobacco rattle virus 2 (TRV2)-myc fruits reached the mature green stage. TORC-deficient fruits showed early accumulation of carotenoid lycopene and reduced cellulose deposition in pericarp cell walls. The early ripening fruits had higher levels of transcripts related to fruit ripening transcription factors, ethylene biosynthesis, carotenoid synthesis, and cell wall modification. Finally, the early ripening phenotype in Micro-Tom tomato was reproduced in the commercial cultivar Moneymaker tomato by VIGS of the TORC genes. Collectively, these results demonstrate that TORC plays an important role in tomato fruit ripening by modulating the transcription of various ripening-related genes.

• Asian-Australasian Journal of Animal Sciences
• /
• 제31권2호
• /
• pp.218-224
• /
• 2018

Objective: This study evaluated the effects of different levels of protein concentrate supplementation on the growth performance of yak calves, and correlated the growth rate to changes occurring in the plasma- amino acids, -insulin profile, and signaling activity of mammalian target of rapamycin (mTOR) cascade to characterize the mechanism through which the protein synthesis can be improved in early weaned yaks. Methods: For this study, 48 early (3 months old) weaned yak calves were selected, and assigned into four dietary treatments according to randomized complete block design. The four blocks were balanced for body weight and sex. The yaks were either grazed on natural pasture (control diet) in a single herd or the grazing yaks was supplemented with one of the three protein rich supplements containing low (17%; LP), medium (19%; MP), or high (21%; HP) levels of crude proteins for a period of 30 days. Results: Results showed that the average daily gain of calves increased (0.14 vs 0.23-0.26 kg; p<0.05) with protein concentrates supplementation. The concentration of plasma methionine increased (p<0.05; 8.6 vs $10.1-12.4{\mu}mol/L$), while those of serine and tyrosine did not change (p>0.05) when the grazing calves were supplemented with protein concentrates. Compared to control diet, the insulin level of calves increased (p<0.05; 1.86 vs $2.16-2.54{\mu}IU/mL$) with supplementation of protein concentrates. Addition of protein concentrates up-regulated (p<0.05) expression of mTOR-raptor, mammalian vacuolar protein sorting 34 homolog, the translational regulators eukaryotic translation initiation factor 4E binding protein 1, and S6 kinase 1 genes in both Longissimus dorsi and semitendinosus. In contrast, the expression of sequestosome 1 was down-regulated in the concentrate supplemented calves. Conclusion: Our results show that protein supplementation improves the growth performance of early weaned yak calves, and that plasma methionine and insulin concentrations were the key mediator for gene expression and protein deposition in the muscles.

• 한국환경생태학회지
• /
• 제26권2호
• /
• pp.186-191
• /
• 2012

붉은배새매($Accipiter$ $soloensis$)는 국내에서 가장 흔히 번식하는 맹금류에 해당함에도 불구하고, 이 종의 번식기 공간이용에 대한 정보는 부족한 실정이다. 붉은배새매의 번식기 세력권과 행동권을 파악하기 위하여 국내에서 번식하는 6쌍(2005년 4쌍, 2006년 2쌍)의 수컷을 6월부터 7월까지 관찰하였다. 이를 통해 수컷이 3회 이상 반복적으로 이용하는 주요 지점과 명확한 세력권 방어 행동을 보이는 지점을 확인하고, 이를 GIS 프로그램으로 분석하였다. 확인된 $25.2{\pm}5.3$개 지점을 중심으로 100% 최소다각형법(minimum convex polygon)을 이용하여 분석한 결과, 붉은배새매의 번식기 세력권은 $4.62{\pm}0.90$ ha, 행동권은 $22.57{\pm}5.12$ ha에 해당하는 것으로 나타났다. 본 연구에서 확인된 붉은배새매의 세력권과 행동권은 비록 기존에 보고된 값보다 넓었으나, 전체 번식기에 걸쳐 이용하는 절대적인 공간 규모가 여전히 작다는 점을 보여준다. 이는 붉은배새매가 먹이를 제공할 수 있는 좁은 서식지, 특히 0.6-2.0 ha에 불과한 논에서 발생할 수 있는 환경 변화나 자원 고갈에도 상당히 취약할 수 있다는 것을 의미한다. 본 연구는 관찰을 통한 세력권 추정에 해당하지만, 붉은배새매의 보전과 관리, 향후 연구를 위한 기초연구로서의 중요성이 있다고 판단된다.