• Title/Summary/Keyword: Rapid test

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Acute-onset respiratory signs in a Labrador Retriever with a positive SARS-CoV-2 rapid antigen test and infection confirmed by RT-PCR analysis: a case report

  • Mark, Gosling;Jessica, Bacon
    • Journal of Veterinary Science
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    • v.23 no.6
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    • pp.80.1-80.6
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    • 2022
  • A 10-year-old male neutered Labrador Retriever presented with a history of acute-onset tachypnoea, lethargy and anorexia. The dog was pyrexic, tachypnoeic and dyspnoeic on examination. A rapid antigen test for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was performed on an oropharyngeal swab and yielded a positive result. SARS-CoV-2 infection was subsequently confirmed by reverse transcription polymerase chain reaction (RT-PCR) analysis. Both of the dog's owners had positive rapid antigen test and RT-PCR analysis results for SARS-CoV-2. Additional diagnostics included computed tomography. Resolution of the dog's clinical signs was achieved with symptomatic treatment.

Cost-Effectiveness of Voluntary HIV Testing Strategies in a Very Low-Prevalence Country, the Republic of Korea

  • Lee, Young Hwa;Bang, Ji Hwan;Park, Sang Min;Kang, Cho Ryok;Cho, Sung-Il;Oh, Myoung-don;Lee, Jong-Koo
    • Journal of Korean Medical Science
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    • v.33 no.46
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    • pp.304.1-304.7
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    • 2018
  • Background: The Republic of Korea has a very low prevalence of human immunodeficiency virus (HIV) infection, but the number of new HIV diagnoses has steadily risen, strongly indicating a large number of undetected HIV infections. Thus, it is important for Korean public health authorities to adopt and encourage cost-effective HIV detection tools, such as rapid HIV screening tests. In this study, we aimed to evaluate the cost-effectiveness of enzyme-linked immunosorbent assays (ELISA) and rapid tests in a public health center (PHC) setting. Methods: We developed a decision analytic model to assess the per-examinee cost and the cost-effectiveness of identifying HIV patients in a PHC setting using two HIV testing strategies: conventional HIV screening by ELISA versus rapid HIV testing. Analysis was performed in two scenarios: HIV testing in an average-risk population and in a high-risk population. Results: Compared to the ELISA, the rapid test was cost-saving and cost-effective. The per-examinee cost was USD 1.61 with rapid testing versus USD 3.38 with ELISA in an average-risk population, and USD 4.77 with rapid testing versus USD 7.62 with ELISA in a high-risk population. The cost of identifying a previously undiagnosed HIV case was USD 26,974 with rapid testing versus USD 42,237 with ELISA in an average-risk population, and USD 153 with rapid testing versus USD 183 with ELISA in a high-risk population. Conclusion: Rapid testing would be more cost-effective than using conventional ELISA testing for identifying previously undiagnosed HIV-infected cases in Korea, a country with extremely low HIV prevalence.

Rapid Evaluation Method for Blast Furnace Slag Fineness and Influence of Fineness on Properties of Cement Mortar (고로슬래그의 분말도 신속평가 및 분말도가 시멘트 모르타르의 특성에 미치는 영향)

  • Han, Cheon-Goo;Joo, Eun-Hee
    • Journal of the Architectural Institute of Korea Structure & Construction
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    • v.34 no.5
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    • pp.13-18
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    • 2018
  • In this research, regarding the type three blast furnace slag (BS) regulated by KS F 2563 and supplied to actual ready mixed concrete plant, the fineness on specification and actually measured fineness by Blain test were compared, and by applying the hydrometer method used for early prediction of concrete strength, the feasibility of the hydrometer method for acquisition inspection of BS was analyzed. Additionally, the influence of various fineness of BS on properties of cement mortar was also assessed. According to the experimental results of this research, correlation of fineness values between specification and actually measured data were not matched. In the case of the rapid evaluation method using hydrometer, a good relation was shown between the fineness data obtained from hydrometer and Blain test. furthermore, from the cement mortar properties test, there was a good relation was obtained between fineness data from rapid evaluation method by hydrometer and cement mortar properties, while there was no clear relation between fineness data from specification and cement mortar properties. Hence, as a qulity controlling method of BS fineness, a rapid evaluation method using hydrometer is suggested as a new method.

A Comparative Evaluation of Three Rapid Tests of Syphilis and ARCHITECT Syphilis TP

  • Kim, Won-Shik
    • Korean Journal of Clinical Laboratory Science
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    • v.43 no.1
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    • pp.1-5
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    • 2011
  • The infection rate of syphilis is still increasing in the world especially in developing countries and the infection is often seen in large amounts of clinical specimens. For the diagnosis of this disease, Rapid Plasma Reagin (RPR)/Venereal Disease Research Laboratory (VDRL) has still been used as one of major primary methods to diagnose syphilis even though the test readings are somewhat subjective with high false positive rates. Recently, the automatic ARCHITECT Syphilis TP, which is based on the detection of the TP-specific antibodies, has been introduced in many laboratories. Therefore, the clinical assessment of the method is needed to provide primary diagnosis of syphilis at the moment. We evaluated 3 different manual rapid kits and ARCHITECT Syphilis TP comparing with RPR/FTA-ABS and analysed their diagnostic properties. From February 2006 to April 2008, 203 positive and 250 negative specimens, obtained from Chungbuk National University Hospital were used for the evaluation. In the evaluation between manual rapid kits, their specificities were as high as 99.2 ~ 99.6% while their sensitivities were observed with little differences; 98.0% (199/203) for Kit A, 96.6% (196/203) for Kit B, and 97.4% (197/203) for Kit S. In the case of ARCHITECT Syphilis TP test, it showed 100% specificity (250/250) and 98.5% sensitivity (249/250). Kappa values comparing with RPR/FTA-ABS were 0.978 for Kit A, 0.964 for Kit B and Kit S, and 0.987 for ARCHITECT Syphilis TP. From our evaluation, we found out that manual rapid tests and ARCHITECT Syphilis TP have very good clinical accuracies and high kappa agreements with RPR/FTA-ABS. Due to its automation and quick simultaneous diagnosis with another serological markers, we suggest that the ARCHITECT Syphilis TP is one of best suitable method for the primary diagnosis of syphilis and that it might be able to replace RPR method in the laboratories.

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Implementation of Impedance Matching Circuit for ATE (고속 ATE 시스템을 위한 임피던스 정합회로 구현)

  • Kim, Jong-Won;Seo, Yong-Bae;Lee, Yong-Sung
    • Journal of the Semiconductor & Display Technology
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    • v.5 no.4 s.17
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    • pp.17-22
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    • 2006
  • In the manufacturing processes of semiconductor, test process is important for quality of products. In the manufacturing process of dynamic memory, memory test is more important. So, automatic test equipment(ATE) is used necessarily. But, according to increase of speed of dynamic memory operation, the rapid test equipment is needed. Impedance matching between ATE and dynamic memory is expected to be an important problem for making a rapid test equipment over 1Gbps. According to increase of speed, inner impedance of ATE also works on important parameter for test. This paper is about the method that is for impedance matching of inner impedance and coaxial cable occurring in manufacturing of ATE. We proved effects of inner impedance by electric theory and verified the method of impedance matching using computer simulation.

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Applicability Study of the Rapid Carbonation Test Equipment for Concrete (콘크리트 급속 촉진 탄산화 장비의 적용성 연구)

  • Choi, Young-Jun;Lee, Kwang-Myong;Kim, Joo-Hyung;Jung, Sang-Hwa;Lee, Myung-Kyu
    • Proceedings of the Korea Concrete Institute Conference
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    • 2006.11a
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    • pp.601-604
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    • 2006
  • Reinforcement corrosion is the most important durability problem of reinforced concrete structures. One of the important factors affecting the steel corrosion is carbonation. However, existing carbonation test takes several months to obtain the results. Therefore, in this study, new rapid carbonation test equipment for concrete was developed and its applicability was investigated. The testing period can be reduced by increasing $CO_2$ concentration up to 100% in the equipment. It is found from the test results that the carbonation depth of concrete specimens tested for 2 weeks was $3{\sim}5$ times greater than that of specimens tested by existing test method. In conclusion, it would be possible to get the reliable test results enough to evaluate the durability of concrete structures in a short-period.

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Diagnostic Accuracy of the Quidel Sofia Rapid Influenza Fluorescent Immunoassay in Patients with Influenza-like Illness: A Systematic Review and Meta-analysis

  • Lee, Jonghoo;Song, Jae-Uk;Kim, Yee Hyung
    • Tuberculosis and Respiratory Diseases
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    • v.84 no.3
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    • pp.226-236
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    • 2021
  • Background: Although the Quidel Sofia rapid influenza fluorescent immunoassay (FIA) is widely used to identify influenza A and B, the diagnostic accuracy of this test remains unclear. Thus, the objective of this study was to determine the diagnostic performance of this test compared to reverse transcriptase-polymerase chain reaction. Methods: A systematic literature search was performed using MEDLINE, EMBASE, and the Cochrane Central Register. Pooled sensitivity, specificity, diagnostic odds ratio (DOR), and a hierarchical summary receiver-operating characteristic curve (HSROC) of this test for identifying influenza A and B were determined using meta-analysis. A sensitivity subgroup analysis was performed to identify potential sources of heterogeneity within selected studies. Results: We identified 17 studies involving 8,334 patients. Pooled sensitivity, specificity, and DOR of the Quidel Sofia rapid influenza FIA for identifying influenza A were 0.78 (95% confidence interval [CI], 0.71-0.83), 0.99 (95% CI, 0.98-0.99), and 251.26 (95% CI, 139.39-452.89), respectively. Pooled sensitivity, specificity, and DOR of this test for identifying influenza B were 0.72 (95% CI, 0.60-0.82), 0.98 (95% CI, 0.96-0.99), and 140.20 (95% CI, 55.92-351.54), respectively. The area under the HSROC for this test for identifying influenza A was similar to that for identifying influenza B. Age was considered a probable source of heterogeneity. Conclusion: Pooled sensitivities of the Quidel Sofia rapid influenza FIA for identifying influenza A and B did not quite meet the target level (≥80%). Thus, caution is needed when interpreting data of this study due to substantial betweenstudy heterogeneity.

Effect of Rapid Cycle Deliberate Practice Advanced Life Support Simulation Education on Nurse's Performance, Confidence, and Satisfaction (Rapid Cycle Deliberate Practice 전문 소생술 시뮬레이션 교육이 간호사의 수행 능력, 자신감과 만족도에 미치는 효과)

  • Kim, Mi Young;Kim, Sung Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.11
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    • pp.44-55
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    • 2019
  • This study was undertaken to examine changes in the performance of nurses before and after initial cardiac arrest, and compare the performance, confidence, and satisfaction between two groups: group 1, Rapid Cycle Deliberate Practice simulation method; group 2, traditional simulation method. The participants were 122 nurses (group 1: 62, group 2: 60). Data were collected from March 18 to 29, 2019 and analyzed using the SPSS Version 23.0 program, by applying descriptive statistics, Fisher's exact test, t-test, Wilcoxon sign rank test, and Mann-Whitney U-test. Comparing the educational effects of the traditional simulation training vs. RCDP simulation training, some items of performance were significantly different (z=-2.02, p=0.044 / z=-2.42, p=0.015 / z=-3.03, p=0.002), but no difference was observed in the levels of confidence (z=0.388, p=0.699) and satisfaction (t=0.72, p=0.476) between the two groups. This study confirms that both training methods are effective teaching modules for enhancing the nurse's ability to perform resuscitation with confidence. Hence, we suggest applying the appropriate simulation method, according to the subjects included during education, and contents in the training of Advanced Life Support for nurses. Effectiveness of the modules can be ascertained by applying the RCDP simulation training method in various fields.

Urease를 이용한 위점막 시료에서 Helicobacter pylori의 신속한 진단법

  • Lee, Hak-Seong;No, Im-Hwan;Choe, Tae-Bu;Lee, Jong-Hwa
    • 한국생물공학회:학술대회논문집
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    • 2000.11a
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    • pp.264-265
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    • 2000
  • Helicobacter pylori(H. pylori) is the causative agent of chronic gastritis and the single most important factor in peptic ulcer disease, however, the pathogenetic mechanisms underlying H, pylori infection are not well understood. Futhermore, there is a strong association between H. pylori infection and gastric cancer. Various diagnostic methods for detecting H. pylori infection are available. These can be divided into invasive methods, requiring endoscopy, and non-invasive tests, mainly 13C-urea breath tests and serologic detection of antibodies. Rapid urease test is the most recommendable endoscopic test for the diagnosis of H. pylori infection, presently. CLO test kit is the represent of rapid urease test kits. The principles of CLO test kit is that hydrolysis of urea by urease Is detected by a dye indicators showing a color change. Our device is used same principle but we improved the reaction time is more faster and positive color change is more distinctive from the color of the negative specimen. So, this kit is more reliable because it response faster and accuracy.

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E-commerce Architecture Evaluation Through Web Stress Test (웹 스트레스 테스트를 통한 전자상거래 아키텍쳐 평가)

  • Lee, Young-Hwan;Park, Jong-Soon
    • Information Systems Review
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    • v.3 no.2
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    • pp.277-288
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    • 2001
  • Of critical importance to the success of any e-commerce site are the two factors: rapid application development and quick response time. A three-tier architecture composed of presentation layer, business layer, and data access layer emerges to allow rapid changes in user interface, business logic, and database structures. Too often, such a logical three-tier architecture is considered as requiring a three-tier physical architecture: Web server, application server, and database server running on separate computers. Contrary to the common belief, a Web stress test reveals that the three-tier logical architecture implemented on a two-tier physical platform guarantees a quicker response time due to the reduction in cross-machine communications. This would lead business firms to economize their spending on e-commerce: increasing the number of physical servers to expedite transaction is not necessarily the best solution. Before selecting a particular hardware configuration, a Web stress test needs to be conducted to compare the relative merits of alternative physical architectures. Together with capacity planning, Web stress test emerges as a powerful tool to build robust, yet economical e-commerce sites.

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