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http://dx.doi.org/10.4142/jvs.22119

Acute-onset respiratory signs in a Labrador Retriever with a positive SARS-CoV-2 rapid antigen test and infection confirmed by RT-PCR analysis: a case report  

Mark, Gosling (Wear Referrals)
Jessica, Bacon (Wear Referrals)
Publication Information
Journal of Veterinary Science / v.23, no.6, 2022 , pp. 80.1-80.6 More about this Journal
Abstract
A 10-year-old male neutered Labrador Retriever presented with a history of acute-onset tachypnoea, lethargy and anorexia. The dog was pyrexic, tachypnoeic and dyspnoeic on examination. A rapid antigen test for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) was performed on an oropharyngeal swab and yielded a positive result. SARS-CoV-2 infection was subsequently confirmed by reverse transcription polymerase chain reaction (RT-PCR) analysis. Both of the dog's owners had positive rapid antigen test and RT-PCR analysis results for SARS-CoV-2. Additional diagnostics included computed tomography. Resolution of the dog's clinical signs was achieved with symptomatic treatment.
Keywords
SARS-CoV-2; antigen; dog; case report;
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1 Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382(8):727-733.   DOI
2 World Health Organization. WHO Coronavirus (COVID-19) Dashboard [Internet]. Geneva: World Health Organization; https:/covid19.who.int. Updated 2022. Accessed 2022 April 4.
3 Calvet GA, Pereira SA, Ogrzewalska M, Pauvolid-Correa A, Resende PC, Tassinari WS, et al. Investigation of SARS-CoV-2 infection in dogs and cats of humans diagnosed with COVID-19 in Rio de Janeiro, Brazil. PLoS One. 2021;16(4):e0250853.
4 Sit TH, Brackman CJ, Ip SM, Tam KW, Law PY, To EM, et al. Infection of dogs with SARS-CoV-2. Nature. 2020;586(7831):776-778.   DOI
5 Miro G, Regidor-Cerrillo J, Checa R, Diezma-Diaz C, Montoya A, Garcia-Cantalejo J, et al. SARS-CoV-2 infection in one cat and three dogs living in COVID-19 positive households in Madrid, Spain. Front Vet Sci. 2021;8:779341.
6 Kevadiya BD, Machhi J, Herskovitz J, Oleynikov MD, Blomberg WR, Bajwa N, et al. Diagnostics for SARS-CoV-2 infections. Nat Mater. 2021;20(5):593-605.   DOI
7 Peto T, Affron D, Afrough B, Agasu A, Ainsworth M, Allanson A, et al. COVID-19: rapid antigen detection for SARS-CoV-2 by lateral flow assay: a national systematic evaluation of sensitivity and specificity for mass-testing. EClinicalMedicine. 2021;36:100924.
8 Animal & Plant Health Agency. APHA Briefing Note 09/21. SARS-CoV-2 in Animals - Case Definition, Testing and International Reporting Oblogations [Internet]. http://apha.defra.gov.uk/documents/ov/Briefing-Note-0921.pdf. Updated 2021. Accessed April 4, 2022.
9 Lappin MR, Blondeau J, Boothe D, Breitschwerdt EB, Guardabassi L, Lloyd DH, et al. Antimicrobial use guidelines for treatment of respiratory tract disease in dogs and cats: antimicrobial guidelines working group of the International Society for Companion Animal Infectious Diseases. J Vet Intern Med. 2017;31(2):279-294.
10 Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, et al. Dexamethasone in hospitalised patients with COVID-19. N Engl J Med. 2021;384(8):693-704.   DOI