• 제목/요약/키워드: Rapid assessment method

검색결과 236건 처리시간 0.023초

방사 면역측정법에 의한 혈청내 갑상선 유리홀몬 측정의 임상적의의에 대한 기본적 검토 (An Assessment of Measurement of Serum Free $T_3,\;T_4$ by Radioimmunoassay)

  • 김영훈;이형호;안희권;김숙주;김준석;안일민;이창홍;박승철
    • 대한핵의학회지
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    • 제19권1호
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    • pp.113-117
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    • 1985
  • The present study was undertaken to examine serum concentration of free $T_3,\;T_4$, in various functional states of the thyroid by Amerlex RIA kit method, which uses unidentified $T_3,\;T_4-labelled$ analogues, said to be unreactive with $T_3,\;T_4-binding$ proteins in serum, together with an antibody that binds both analogue and $T_3,\;T_4$. The test method has been compared with free $T_4$ index, which was product of total serum thyroxine and $T_3$ resin uptake ratio. Free $T_4$ value by this method was found to have a highly significant positive correlation with a free $T_4$ index (r; 0.957, p<0.005) and total $T_4$ (r:0.89, p<0.005) also, it was similar to other free $T_4$ measuring methods previously reported. So, it was showen to have the clinical utility as the screening test for thyroid function because it was a rapid; convinient, and reliable method for quantifying the free $T_4,\;T_3$ concentration in various thyroidal functional states.

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경량벽체 표면의 패임에 대한 시각적 판단방법에 관한 기초적 연구 (A basic study on Visual judgment method for the Dent of Lightweight wall surface)

  • 김진식;신윤호;최수경
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2015년도 추계 학술논문 발표대회
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    • pp.36-37
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    • 2015
  • Recently, there has been a rapid increase in demand for lightweight walls for their use as interior partitions, as types of structure have gradually changed from shear wall structures to column structures or flat plate column wall systems. The lack of resisting force in lightweight walls is found by measuring the depth of dents in impact resistance tests, but it is not a direct factor of impact resistance. However, in the user's position, dents of over a certain size are clearly a factor that visually reminds the need for repair. In this study, we reviewed relative methods of assessment of the need for repair based on the visual means of determination (sensory test) on the dents on lightweight walls. Dents were found to stand out starting from depths of about 4mm, and the depth of roughly 5mm was found to be the criterion for determining the necessity of repair for men, while it was 4mm for women.

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Establishment of CALUX Bioassay for Dioxin Determination

  • Joung, Ki-Eun;Chung, Young-Hee;Sheen, Yhun-Yhong
    • 한국환경성돌연변이발암원학회지
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    • 제24권3호
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    • pp.137-142
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    • 2004
  • Dioxin-like compounds are ubiquitous environmental polltants that could be accumulated in biological system and toxic to human and wildlife. Given this issue, it is important to develop a reliable dioxin detection methods for a rational risk assesment of dioxin-like compounds. In this study, we tried to set up and validate a sensitive, reliable risk assessment of dioxin-like compounds. In this study, we tried to set up and validate a sensitive, reliable and rapid bioassay model, CALUX bioassay as a screening tool for routine measurement of dioxin-like conpounds in environmental matrices. For the valisation of CALUX bioassay, firstly, we performed dose-response assay for 2,3,7,8-TCDD, most potent dioxin-like compound, using two different methods CALUX and EROD assay. Induction of luciferase activity and CYPIA catalyzed EROD activity were dose-dependently induced by 2,3,7,8-TCDD, with initial induction at 0.1 pM and maximal induction at 1 nM. In order t determine whether the CALUX bioassay could predict the effects of dioxin-like compounds, 2,3,7,8-TCDD dose-response from CALUX was compared with that from EROD assay. The correlation coefficient ($r^2$) was found to be 0.89, indicating a good correlation between two different methods and the possibility of CALUX bioassay as a useful dioxin detecting method.

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개에서 외이도의 초음파학적 평가 (Ultrasonographic Evaluation of the External Ear Canal in Dogs)

  • 이해운;엄기동;성윤상;이정민;이종원;김정은;장광호;이근우;장동우
    • 한국임상수의학회지
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    • 제21권2호
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    • pp.149-153
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    • 2004
  • This study was to determine the procedure for ultrasonographic imaging of the canine external ear canal(ECC). By infusion of warm saline solution into the ear canal, a real-time B mode ultrasonographic examination of the ECC was performed in five healthy Beagle dogs and two dogs with severe otitis externa. The ultrasonography was very useful to detect the structures of the ECC and the tympanic membrane. An 11 NHz linear probe was permitted to assess an anechoic lumen of the ECC and a hyperechoic cartilage surrounding the ear canal. In two dogs with otitis externa, it could be assessed the ECC with ultrasonography without ear cleansing. A lumen of the ECC was irregular and a cerumen could be seen, but edematous inflammatory changes of the ECC could not be identified. The results suggest that ultrasonography of the ECC with an 11 NHz linear probe after infusing the saline solution into the ear canal may be an accurate, non-invasive, rapid, and widely available method for assessment of the ear canal diseases such as otitis externa, polyp, stenosis, hyperplasia, and foreign body in dogs.

흐름 경사면의 경사도에 따른 토석류 흐름의 특성 분석 (Analysis of Characteristic of Debris Flow with Angle of Slope)

  • 이준선;송창근;이승오
    • 한국안전학회지
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    • 제31권2호
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    • pp.49-56
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    • 2016
  • In Korea, there exist many mountains, and sudden storms occur during the summer season. When severe rainstorm events occur in steep slope topography, risk of debris flow is increased. Once debris flow occurs in urban area, it may cause casualties and physical damages due to rapid debris flow velocity along a steep slope. Accordingly, preventing method of sediment-related disaster for demage mitigation are essential. Recently, various studies on debris flow have been conducted. However, the prediction of the physical propagation of debris flow along the steep slope was not thoroughly investigated. Debris flow is characterized by various factors such as topography, properties of debris flow, amount of debris flow. In the study the numerical simulation was focused on the topographic factor. Fundamental analysis of the risk area was implemented with emphasis on the propagation length, thickness, and the development of maximum velocity. The proposed results and the methodology of estimating the structural vulnerability would be helpful in predicting the behavior and the risk assessment of debris flow in urban area. These results will be able to estimate the vulnerability of urban areas affected the most damage by debris flow.

A Solution to Privacy Preservation in Publishing Human Trajectories

  • Li, Xianming;Sun, Guangzhong
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제14권8호
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    • pp.3328-3349
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    • 2020
  • With rapid development of ubiquitous computing and location-based services (LBSs), human trajectory data and associated activities are increasingly easily recorded. Inappropriately publishing trajectory data may leak users' privacy. Therefore, we study publishing trajectory data while preserving privacy, denoted privacy-preserving activity trajectories publishing (PPATP). We propose S-PPATP to solve this problem. S-PPATP comprises three steps: modeling, algorithm design and algorithm adjustment. During modeling, two user models describe users' behaviors: one based on a Markov chain and the other based on the hidden Markov model. We assume a potential adversary who intends to infer users' privacy, defined as a set of sensitive information. An adversary model is then proposed to define the adversary's background knowledge and inference method. Additionally, privacy requirements and a data quality metric are defined for assessment. During algorithm design, we propose two publishing algorithms corresponding to the user models and prove that both algorithms satisfy the privacy requirement. Then, we perform a comparative analysis on utility, efficiency and speedup techniques. Finally, we evaluate our algorithms through experiments on several datasets. The experiment results verify that our proposed algorithms preserve users' privay. We also test utility and discuss the privacy-utility tradeoff that real-world data publishers may face.

응급실에 내원한 만성 폐쇄성 폐질환 환자의 호흡곤란 속성에 관한 연구 (A Study on Characteristics of Dyspnea in Patients with Chronic Obstructive Pulmonary Disease in the Emergency Department Visits)

  • 양진주
    • 성인간호학회지
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    • 제17권5호
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    • pp.813-821
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    • 2005
  • Purpose: The purpose of this study was to examine descriptors of dyspnea and clinical characteristics in patients with COPD at ED visit. Method: The study design was a descriptive survey, and 46 patients with COPD complaining of dyspnea were participated during their visits to the ED of C university hospital in G city, from October 1, 2004 to April 8, 2005. Result: The qualitative characteristics of dyspnea at the time of decision to the ED visit were short of breath (71.7%), tight (32.6%), hard to breathe (15.2%), smothering or suffocating (10.9%), gasping (8.7%), couldn't breathe (6.5%), constricted (2.2%), and hunger for air (2.2%). In the item of dyspnea checklists, My chest felt tight was the most common description among subjects. As the result of factor analysis of dyspnea checklists, the first factor was characterized rapid and shallow, the second was suffocating/smothering, the third was hunger for air, and the fourth was constricted. Conclusion: This study suggests that a checklist of dyspnea descriptors based on this findings would be utilized as a tool of initial and ongoing assessment for dyspneic patients with COPD in the ED after identifying the validity and reliability of the checklist.

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전기자동차 보급을 위한 농촌지역의 주유소 기반 급속 충전인프라 구축 방안 분석 (Analysis of Construction Plans of Rapid Charging Infrastructures based on Gas Stations in Rural Areas to Propagate Electric Vehicles)

  • 김솔희;김태곤;서교
    • 농촌계획
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    • 제21권1호
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    • pp.19-28
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    • 2015
  • As environmental concerns including climate change drive the strong regulations for car exhaust emissions, electric vehicles attract the public eye. The purpose of this study is to identify rural areas vulnerable for charging infrastructures based on the spatial distributions of the current gas stations and provide the target dissemination rates for promoting electric cars. In addition, we develop various scenarios for finding optimal way to expand the charging infrastructures through the administrative districts data including 11,677 gas stations, the number of whole national gas stations. Gas stations for charging infrastructures are randomly selected using the Monte Carlo Simulation (MCS) method. Evaluation criteria for vulnerability assessment include five considering the characteristic of rural areas. The optimal penetration rate is determined to 21% in rural areas considering dissemination efficiency. To reduce the vulnerability, the charging systems should be strategically installed in rural areas considering geographical characteristics and regional EV demands.

Distribution of ICT and Analysis of the Digital Components of the Quality of Life

  • PANZABEKOVA, Aksanat;KIREYEVA, Anel A.;SATYBADIN, Azimkhan A.;S.SABYR, Nursymbat
    • 유통과학연구
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    • 제18권12호
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    • pp.67-77
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    • 2020
  • Purpose: Based on the author's adapted invariant choice, this study is to present the methodology and the calculation of the integral index of the digital component of the quality of life. By analyzing the digital indexes, the study is also to discuss distribution of ICT and the digital quality of life of the population of Kazakhstan and its regions. Research design, data, methodology: In this research, the method of calculation of integral assessment of the indicator was used, which indicates index constructs. The study analyzed objective secondary data for the period 2017-2019, which was the database from official websites of the Committee on Statistics of the Republic of Kazakhstan. Results: The study produced an integral code for assessing digital components of living standards of the population, consisting of five groups sub-indexes. Conclusions: Based on the provided analyses, we can confirm the existence of a significant difference of all the indicators of digital living standards of the population between the two leading cities: Almaty city and Nur-Sultan city. Furthermore we can deduce the differences of the examined indexes for other regions of Kazakhstan. Despite the rapid adoption of digital technologies, Kazakhstan still has significant digital gaps among cities indicating regional differences in the speed of implementation and distribution of digital technologies.

Comparative Assessment of Diagnostic Performance of Cytochrome Oxidase Multiplex PCR and 18S rRNA Nested PCR

  • Kumari, Preeti;Sinha, Swati;Gahtori, Renuka;Quadiri, Afshana;Mahale, Paras;Savargaonkar, Deepali;Pande, Veena;Srivastava, Bina;Singh, Himmat;Anvikar, Anupkumar R
    • Parasites, Hosts and Diseases
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    • 제60권4호
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    • pp.295-299
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    • 2022
  • Malaria elimination and control require prompt and accurate diagnosis for treatment plan. Since microscopy and rapid diagnostic test (RDT) are not sensitive particularly for diagnosing low parasitemia, highly sensitive diagnostic tools are required for accurate treatment. Molecular diagnosis of malaria is commonly carried out by nested polymerase chain reaction (PCR) targeting 18S rRNA gene, while this technique involves long turnaround time and multiple steps leading to false positive results. To overcome these drawbacks, we compared highly sensitive cytochrome oxidase gene-based single-step multiplex reaction with 18S rRNA nested PCR. Cytochrome oxidase (cox) genes of P. falciparum (cox-III) and P. vivax (cox-I) were compared with 18S rRNA gene nested PCR and microscopy. Cox gene multiplex PCR was found to be highly specific and sensitive, enhancing the detection limit of mixed infections. Cox gene multiplex PCR showed a sensitivity of 100% and a specificity of 97%. This approach can be used as an alternative diagnostic method as it offers higher diagnostic performance and is amenable to high throughput scaling up for a larger sample size at low cost.