• 한국전자거래학회지
• /
• 제25권3호
• /
• pp.109-130
• /
• 2020

최근 기술의 혁신을 위한 연구개발의 중요성이 커지고 있다. 연구개발의 급속한 발전은 다양한 긍정적 효과가 있지만, 동시에 정보 및 기술에 대한 유출 범죄를 가속화시키는 부정적 영향 또한 존재한다. 본 연구에서는 점차 심각해지는 연구개발 결과물 유출 사고를 대비하기 위해 조직 차원에서 이루어지는 연구개발 환경을 안전하게 보호할 수 있는 연구보안 수준측정 모형을 개발하였다. 먼저 국내외 연구개발 관련 보안정책들을 분석하고 종합하여, 연구보안 수준평가 항목 10개(연구보안 추진체계, 연구시설과 장비 보안, 전자정보 보안, 주요 연구정보 관리, 연구노트 관리, 지식재산권/특허 관리, 기술사업화 관리, 내부연구원 관리, 인가된 제3자 관리, 외부자 관리)를 전문가 인터뷰를 통해 도출하였다. 다음으로, 도출한 연구보안 수준평가 항목을 조직의 연구개발 환경에 다차원적 관점에서 적용 가능하도록 연구보안 수준평가 모형을 설계하였다. 마지막으로 모형에 대한 타당성을 검증하고, 실제 연구개발을 수행하는 조직을 대상으로 시범 적용하여 연구보안 수준을 평가해보았다. 본 연구에서 개발한 연구보안 수준평가 모형은 실제 연구개발을 수행하고 있는 조직 및 프로젝트의 보안 수준을 적절하게 측정하는 데 유용하게 활용될 수 있을 것으로 기대되고, 연구개발을 직접 수행하는 연구원들이 자체적으로 연구보안 체계를 수립하고 보안관리 대책을 마련하는 데 도움이 될 것이라 판단된다. 또한 연구개발을 수행하는 조직 차원의 보안성 향상뿐만 아니라 프로젝트 단위의 연구개발을 안전하게 수행함으로써, 연구개발 투자에 대한 안정적이고 효과적인 성과를 낼 수 있을 것이라 기대한다.

• 약학회지
• /
• 제41권3호
• /
• pp.328-334
• /
• 1997

Pharmacokinetics of DWP401, a recombinant human epidermal growth factor (rhEGF), was studied using radioimmunoassay (RIA) and $^{125}I$-DWP401 in rats. When DWP401 was adm inistered i.v. at doses of 50 and 500 mcg/kg, the plasma DWP401 disappeared biiexponentially with terminal half life of 4.7 and 92.8 min. The $C_{max}$ and $T_{max}$ after s.c. administration of ti at doses of 50 and 500 ${\mu}g$/kg were determined to be 23.6 and 17.5 ng/ml at 50 ${\mu}g$/kg, and 261.4 ng/ml and 36.8 min, respectively. Both the total urinary and biliary recoveries of intact DWP401 2343 very low (<0.4%), probably due to its extensive degradation in the body. the concentration ratio of DWP401 between the organ and plasma decreased especially in the liver and kidney as the dose and time after the dose increased. For example, the liver/plasma and kidney/plasma concentration ratio of DWP401 at 2.5 min after i.v. doses of 50 ${\mu}g$/kg were comparable and much larger than unity. But, the ratio at 2.5 min after i.v. doses of 500${\mu}g$/kg was much larger in the kidney that in than in the liver. These results suggest that the systemic administration of DWP401 might be subject to rapid and extensive clearance from circulation within several hour after main distrbution to liver and kidney.

• 한국식품저장유통학회지
• /
• 제18권5호
• /
• pp.811-816
• /
• 2011

국산 캠벨 얼리 포도과즙을 36 $^{\circ}Brix$로 동결농축한 후 국산 포도로부터 분리된S. cerevisiae S13, D8 균주를 이용하여 아이스와인의 발효를 행하면서 대조균주인 S. cerevisiae Fermivin과 발효특성을 비교하였다. 발효 중 S13과 D8의 경우 Fermivin보다 당도가 다소 빠르게 감소하였으며 빠른 알코올 생성을 보였다. 발효 종료 시점인 9일 후의 알코올 농도는 D8이 15.2%, S13은 14.0%, Fermivin은 12.6%를 나타내었다. 잔존 환원당의 함량은 Fermivin 포도주가 14.0%로 가장 높았으며 D8 포도주는 9.07%, S13 포도 주는 9.77%로 나타났다. 총산 함량은 Fermivin 포도주 약 0.82%에 비하여 D8과 S13 포도주에서 각각 0.97, 0.96%로 다소 높게 나타났으며 pH는 모든 포도주에서 3.65-3.67로 유의적인 차이가 없었다. 아세트알데히드는 D8 포도주가 81.9 ppm으로 다소 높았으며 Fermivin 포도주는 58.8 ppm으로 가장 낮았다. 메탄올 함량은 S13, D8 포도주가 Fermivin 포도주보다 다소 높았으나 과실주의 메탄올 허용 기준치보다는 매우 낮았다. L 값은 6.89-6.99로 일반포도주에 비해 매우 낮게, b 값은 4.37-4.54로 매우 높게 나타났다. 아이스와인의 향과 맛은 S13 포도주가 가장 높은 점수를 받았으며 전반적인 기호도는 D8와 S13 포도주가 Fermivin 포도주보다 높은 점수를 받았다.

• 한국산업융합학회 논문집
• /
• 제21권3호
• /
• pp.117-123
• /
• 2018

Continued R&D investment by the government and corporate support played a major role as the background of the rapid growth of the Republic of Korea. In 2017 of the Republic of Korea, the R&D support size of the government accounted for 19.7 trillion won, accounting for 4.7% of the government budget. Government R&D budgets are increasing by 2.5% each year. In this paper, we analyzed the outcomes of the Busan regional company support project conducted in the 2 years. For the time series analysis, we gathered company support amount by year, sales after company support, employment. We used IBM SPSS(Statistical Package for the Social Sciences) statistics 18 for correlation analysis.

• 한국수소및신에너지학회논문집
• /
• 제18권2호
• /
• pp.207-215
• /
• 2007

The rapid changes of energy environment such as high oil price, united nations framework convention on climate change, and the hydrogen economy have been happening to provide national energy security in the 21st century, we need to build strategic approach for coping with energy environment. From a long-term viewpoint of energy technology development, it's time to develop energy technology with selection and specification. In this study, we build energy technology roadmap for establishing the hydrogen economy with a long-term strategy. We analyze economic spin-offs and commercial potential for establishing energy technology roadmap of energy technology development for establishing the hydrogen economy.

• 한국미생물·생명공학회지
• /
• 제15권2호
• /
• pp.80-83
• /
• 1987

Rhodotorula glutinis IFO 0559에서 유래하는 L-phenylalanine ammonia lyase(EC 4. 3. 1. 5)를 이용하거나, 유도된 세포자체를 이용하여 trans-cinnamic acid로부터 L-phenylalanine을 생합성할 때 극단적인 반응액이 미치는 효소 및 세포의 안정성에 대하여 조사하였다. 그리고 안정제를 첨가한 60％의 glycerol은 효소의 안정화에 효과를 보였으며 trans-cinnamic acid에서 L-phenylalanine으로의 전이율은 80％까지 되었다. 이에 아울러 전이율을 보다 신속하고 정확히 측정할 수 있는 wavelength scanning 방법을 개발하였다.

• Journal of Korea Trade
• /
• 제27권1호
• /
• pp.159-175
• /
• 2023

Purpose - This paper empirically investigates the relationship between born global strategy and the accounting- and market- based financial performance of Korean firms. Further, this study identifies the characteristics of born global firms (BGs) in comparison with non-BG counterparts in terms of size, R&D, and liability. Design/methodology - Using a database of listed Korean SMEs in the manufacturing sector from 2010 to 2020, this study applies panel generalized least squares (GLS) estimation and logistic regression techniques. Findings - This study finds that BG strategy is negatively related to the firm's accounting-based financial performance, while it is positively related to the market-based financial performance. This study also finds that BGs have higher sales volume and more total assets compared to their non-BG counterparts. In addition, Korean BGs spend more on R&D, and at the same time have higher liability. Originality/value - BGs, by definition, are firms that are actively penetrating foreign markets from the early stages of their establishment. Previous studies of Korean BGs have tried to identify the determinants of BGs' rapid internationalization and their superior performance. However, most of these studies have utilized either qualitative case- or survey-based analyses with relatively limited numbers of observations. From a different perspective, this study provides more objective evidence by investigating how the BG strategy affects the financial and market performance of firms, and by characterizing BGs in terms of financial data.

• Current Optics and Photonics
• /
• 제8권2호
• /
• pp.138-150
• /
• 2024

This study is essential for advancing our knowledge about the interaction between long-range high-power lasers and energetic materials, with a particular emphasis on understanding the response of a 155-mm shell under various surface irradiations, taking into account external factors such as atmospheric disturbances. The analysis addresses known limitations in understanding the use of non-realistic targets and the negligence of ambient conditions. The model employs the three-dimensional level-set method, computer-aided design (CAD)-based target design, and a message-passing interface (MPI) parallelization scheme that enables rapid calculations of the complex chemical reactions of the irradiated high explosives. Important outcomes from interaction modeling include the accurate prediction of the initiation time of ignition, transient pressure, and temperature responses with the location of the initial hot spot within the shell, and the relative magnitude of noise with and without the presence of physical ambient disturbances. The initiation time of combustion was increased by approximately a factor of two with atmospheric disturbance considered, while slower heating of the target resulted in an average temperature rise of approximately 650 K and average pressure increase of approximately 1 GPa compared to the no ambient disturbance condition. The results provide an understanding of the interaction between the high-power laser and energetic target at a long distance in an atmospheric condition.

• Journal of Power Electronics
• /
• 제1권2호
• /
• pp.65-70
• /
• 2001

Transmission System Operators are governed by operational security standards that are applied in real time. During system disturbances, the System Operators must rely on the installed protection and control equipment, prior to human intervention. New power electronic solutions bring rapid and repeatable responses to disturbances, which will help System Operators to guarantee a stable system. Last year, Alstom completed the world's first competitively bid STATCOM to support the voltage on National Grid's 400kV network that supplies London and the Southeast from the north of the UK. It is rated ${\pm}75MVAr$ and forms part of a Static Var System (SVS) with a total rating of 0 to 225MVAr. This paper will describe the reasons for its size, location, its chain-link configuration and give examples of its operating performance. The paper will also describe the features that allow this STATCOM to deliver much more than reactive compensation in support of a wider transmission service objective, as system conditions require.

• 한국정보디스플레이학회:학술대회논문집
• /
• 한국정보디스플레이학회 2006년도 6th International Meeting on Information Display
• /
• pp.1198-1201
• /
• 2006

Carbon nanotubes (CNTs) have used as an electron field emitter of the field emission display (FED) due to their characteristics of high-electron emission, rapid response and low power consumption. However, to commercialize the FED with CNT emitter, some fundamental problems regarding life time and emission efficiency have to be solved. In this study, we investigated the metal coated CNT as a field emitter on which metal nanoparticles were coated by chemical modification. Metal nanoparticles, such as Ru, Pd, were synthesized by solution reduction method. The size of the metal nanoparticle has the range of 2 - 5 nm. Surface was modified chemically with the use of ionic surfactant which changed the surface charge of nanoparticles.