• Communications for Statistical Applications and Methods
• /
• v.17 no.3
• /
• pp.309-318
• /
• 2010

The construction of asymptotic confidence intervals is considered for the difference of binomial proportions in two doubly sampled data subject to false-positive error. The coverage behaviors of several likelihood based confidence intervals and a Bayesian confidence interval are examined. It is shown that a hierarchical Bayesian approach gives a confidence interval with good frequentist properties. Confidence interval based on the Rao score is also shown to have good performance in terms of coverage probability. However, the Wald confidence interval covers true value less often than nominal level.

• Communications for Statistical Applications and Methods
• /
• v.17 no.5
• /
• pp.679-688
• /
• 2010

Lee (2010) developed a confidence interval for the difference of binomial proportions in two doubly sampled data subject to false-positive errors. The confidence interval seems to be adequate for a general double sampling model subject to false-positive misclassification. However, in many applications, the false-positive error rates could be the same. On this note, the construction of asymptotic confidence interval is considered when the false-positive error rates are common. The coverage behaviors of nine likelihood based confidence intervals are examined. It is shown that the confidence interval based Rao score with the expected information has good performance in terms of coverage probability and expected width.

• Journal of the Korean Society of Radiology
• /
• v.17 no.3
• /
• pp.351-357
• /
• 2023

This Study Rreceived Subjective Evaluation ROC Evaluation from five projection. of projection. at a University Hospital to Obtain and Diagnose Sharp images of apophyseal joints and Vertral arch of Thoracic vertebrae from thoracic X-ray projection. In the Subjective evaluation, the highest Score was obtained by raising the phantom from Supine to LAO by 70° and scoring 20 points at 5° with the X-ray Tube facing the head. In addition, he scored the highest score of 19 points at 8° with the Prone Phantom standing 60° with RAO and the X-ray Tube facing the head. For Objective Evaluation, the Signal-to-noise ratio, was calculated. ROI was set at 1,564 mm2 to obtain the image signal average value (Mean value) and the Standard deviation (SD value). Objective Evaluation The signal-to-noise ratio, was the highest at 5° toward the head in the LPO 70° position of the phantom in the lying position of the Thoracic spine projection, and the Thoracic Spine was the highest at 8° toward the head of the RAO posture of 5,645.

• The Korean Journal of Applied Statistics
• /
• v.25 no.3
• /
• pp.513-520
• /
• 2012

An Agresti-Coull type test is considered for the difference of binomial proportions in two doubly sampled data subject to false-positive error. The performance of the test is compared with the likelihood-based tests. It is shown that the Agresti-Coull test has many desirable properties in that it can approximate the nominal significance level with compatible power performance.

• Communications for Statistical Applications and Methods
• /
• v.20 no.5
• /
• pp.417-425
• /
• 2013

We consider an extended version of a logarithmic series distribution and discuss the estimation of its parameters by the method of moments and the method of maximum likelihood. Test procedures are suggested to test the significance of the additional parameter of this distribution and all procedures are illustrated with the help of real life data sets. In addition, a simulation study is conducted to assess the performance of the estimators.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.15 no.3
• /
• pp.1599-1605
• /
• 2014

This study aimed to identify the relationship between depression of the elderly and low back pain. Data were obtained from cross-sectional surveys conducted as a part of the Community Health Survey 2008. The final analysis included data from 3,647 of the 3,649 elderly participants (aged over 65 years), as 2 responses were excluded since they were inaccurate. Data were analyzed with SPSS for Windows (ver. 19.0), using a Rao-Scott ${\chi}^2$-test and Logistic regression by applying a proper weighting. The significance threshold was set as p<0.05. Factors related to the depression of the elderly were low back pain, subjective health status, average sleep duration. Further, depression score was 1.38 times higher in elderly adults with low back pain than elderly adults without low back pain. In order to decrease depression of the elderly with low back pain the development of a program to decrease activities of daily living discomfort and management of low back pain will need to be determined. It is considered necessary to conduct further study to follow through the analysis of the various variables by applying them to the elderly with low back pain and depression.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.2
• /
• pp.815-821
• /
• 2016

Background: Development of chronic myeloid leukemia (CML) involves formation of double strand breaks (DSBs) which are initially sensed by the ataxia telangiectasia mutated (ATM) signal kinase to induce a DNA damage response (DDR). Mutations or single nucleotide polymorphisms in ATM gene are known to influence the signaling capacity resulting in susceptibility to certain genetic diseases such as cancers. Materials and Methods: In the present study, we have analyzed -5144A>T (rs228589) and C4138T (rs3092856) polymorphisms of theATM gene through polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 925 subjects (476 CML cases and 449 controls). Results: The A allele of -5144A>T polymorphism and T allele of C4138T polymorphism which were known to be influencing ATM signaling capacity are significantly associated with enhanced risk for CML independently and also in combination (evident from the haplotype and diplotype analyses). Significant elevation in the frequencies of both the risk alleles among high risk groups under European Treatment and Outcome Study (EUTOS) score suggests the possible role of these polymorphisms in predicting the prognosis of CML patients. Conclusions: This study provides the first evidence of association of functional ATM gene polymorphisms with the increased risk of CML development as well as progression.

• Journal of Preventive Medicine and Public Health
• /
• v.55 no.4
• /
• pp.407-413
• /
• 2022

Objectives: This study provides insights on the impact of a targeted intervention (TI) programme on behaviour change among injecting drug users (IDUs) in India. Methods: This paper examined the data from the Integrated Biological and Behavioural Surveillance 2014-2015 for IDUs in India. Logistic regression was performed to understand the factors (TI programme services) that affected injecting risk behaviours by adjusting for covariates. Propensity score matching was conducted to understand the impact of the TI programme on using new needles/syringes and sharing needles/syringes in the most recent injecting episode by accounting for the covariates that predicted receiving the intervention. Results: Participants who received new needles and syringes from peer educators or outreach workers were 1.3 times (adjusted odds ratio, 1.29; 95% confidence interval [CI], 1.09 to 1.53) more likely to use new needles/syringes during most recent injecting episode than participants who did not receive needles/syringes. The matched-samples estimate (i.e., average treatment effect on treated) of using new needles in the most recent injecting episode showed a 2.8% (95% CI, 0.0 to 5.6) increase in the use of new needles and a 6.5% (95% CI, -9.7 to -3.3) decrease in needle sharing in the most recent injecting episode in participants who received new needles/syringes. There was a 2.2% (95% CI, -3.8 to -0.6) decrease in needle sharing in the most recent injecting episode among participants who were referred to other services (integrated counselling and testing centre, detox centres, etc.). Conclusions: The TI programme proved to be effective for behaviour change among IDUs, as substantiated by the use of new needles/syringes and sharing of needles/syringes.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.2
• /
• pp.829-833
• /
• 2016

Purpose: To investigate the work associated stress and nicotine dependence among law enforcement personnel in Mangalore, India. Materials and Methods: A cross-sectional questionnaire survey was conducted among law enforcement personnel in Mangalore, India. Demographic details, stress factors experienced at work and nicotine dependency were the variables studied. The extent of stress factors experienced at work was assessed using the Effort-Reward Imbalance scale (ERI). Nicotine dependence was measured using the Fagerstrom Test for Nicotine Dependence (FTND) and the Fagerstrom Test for Nicotine Dependence-Smokeless Tobacco (FTND-ST). Logistic regression was used for the statistical analysis. Results: Three hundred and four law enforcement personnel participated in the study, among whom 68 had the presence of one or more habits like tobacco smoking, tobacco chewing and alcohol use. The mean effort score was $15.8{\pm}4.10$ and the mean reward and mean overcommitment scores were $36.4{\pm}7.09$ and $17.8{\pm}5.32$ respectively. Effort/Reward ratio for the total participants was 1.0073 and for those with nicotine habit was 1.0850. Results of our study demonstrated no significant association between domains of ERI scale and presence of habits but work associated stress was associated with the presence of one or more habits. Compared to constables, head constables had 1.12 times higher risk of having a nicotine habit. Conclusions: Our study implies job designation is associated with nicotine habits. However, there was no association between work associated stress and nicotine dependence among law enforcement personnel in Mangalore.

• Asian-Australasian Journal of Animal Sciences
• /
• v.15 no.8
• /
• pp.1170-1177
• /
• 2002

An experiment was conducted to assess the interaction between genotypes and dietary lysine content in commercial broiler chicks by measuring growth, and response to sheep red blood cells (SRBC) and Escherichia coli (E.coli) inoculation. Female chicks from four genotypes (A=Anak 2000; B=Hubbard; C=Cobb and D=Synthetic broiler) were fed four levels of lysine in diet from d old till the end of experiment. The lysine content of the diet was 9.61, 10.51, 11.41 and 12.31 g/kg. Body weights at 0, 14, 28 and 42 d of age and pen-wise feed intake till 14, 28 and 42 d of age were recorded. Production of antibody against SRBC and resistance to E.coli were measured at 5 d of post inoculation (PI) at 43 d of age. Also, response to phytohemaglutinin-P (PHA-P) was measured at 12 and 24 h of PI at 48 d of age. Genotype by dietary lysine interaction was significant for body weights at 14 and 28 d of age, but not at 42 d of age. Genotype by dietary lysine interaction was not significant for feed efficiency, for antibody titers against SRBC, and for air sac lesion score, relative bodyweight change, and relative weights of bursa and spleen in response to E.coli inoculation. However, a significant interaction was observed between the levels of lysine and dosage of SRBC for antibody titers. There was significant genotype by dietary lysine interaction for cutaneous basophilic hypersensitivity (CBH) response to PHA-P at 12 and 24 h of PI. It may be concluded that to obtain optimum body weight and immunity in commercial broilers the dietary lysine requirement may be recommended specific to the genotype.