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The Effect of Human Albumin Infusion on the Clinical Course of Steroid Sensitive Nephrotic Syndrome (인알부민 투여가 스테로이드 반응성 신증후군의 임상경과에 미치는 영향)

  • Lee Soo Jin;Jeong Ji A;Hwang Soo Ja;Lee Seung Joo
    • Childhood Kidney Diseases
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    • v.4 no.2
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    • pp.102-110
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    • 2000
  • Purpose : Intravenous infusion of albumin has been widely und to relieve severe nephrotic edema in spite of beneficial or harmful effects. The purpose of this study is to examine the harmful effect of albumin on the clinical course of steroid sensitive nephrotic syndrome(SSNS). Method : We prospectively randomized the patients with nephrotic syndrome(biopsy proven or clinically compatible to minimal change nephrotic syndrome) into the albumin group(20$\%$ albumin 1 g/kg) or control group(5$\%$ D/W) between March 1997 and September 1999 at Ewha University Mokdong Hospital. We compared the clinical course of the albumin group(n=13) with the control group(n=13). Results : 1. The duration of steroid therapy until complete remission in the albumin group was significantly longer than the control group($13.7{\pm}6.4\;days\;vs\;7.5{\pm}2.8\;days$)(P<0.05). 2. The remission duration to the first relapse was significantly shorter in the albumin group ($94{\pm}63.5$ days) than the control group($190{\pm}106.4$ days)(P< 0.05). There was no significant difference in the relapse rate within 1 year after complete remission[77$\%$ (10/13) vs 46$\%$ (6/13)](P>0.05) and the relapse frequency per year($1.9{\pm}0.8\;vs\;1.5{\pm}0.5$) between the albumin and control groups. 3. Spot urine protein/creatinine ratio significantly increased in the albumin group at post-albumin 2, 4 days(P<0.05). There was no significant difference in the change of the daily percent weight loss, blood pressure, serum Na, K concentration between the albumin and control groups. Conclusion : Albumin infusion in SSNS delayed the response to steroid and shortened the remission duration to the first relapse. Albumin should be carefully used in nephrotic edema.

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Effect of Pre-wilting on the Forage Quality of Organic Sorghum$\times$Sudangrass Silage (예건이 수수$\times$수단그라스 교잡종 유기 사일리지의 품질에 미치는 영향)

  • Lim, Hyun-Jin;Kim, Jong-Duk;Lee, Hyun-Jin;Jeon, Kyeong-Hup;Yang, Ka-Young;Kwon, Chan-Ho;Yoon, Sei-Hyung
    • Korean Journal of Organic Agriculture
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    • v.17 no.4
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    • pp.519-527
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    • 2009
  • The main nutritional problem of sorghum$\times$sudangrass hybrid silage is low quality and dry matter (DM) contents. This experiment was conducted to evaluate whether field pre-wilting treatment of sorghum$\times$sudangrass hybrid silage increases DM content and forage quality of the silage. The experiment was a randomized complete block design with three replications. The treatments were consisted of five different wilting days: 0 day (direct cut silage), 0.5 day, 1 day, 2 days and 3 days. Sorghum$\times$sudangrass hybrid silage with pre-wilting showed low 4.00 pH values, however direct cut silage (control) showed a 4.30 value because of its high moisture content. The DM content of sorghum$\times$sudangrass hybrid silage with pre-wilting was high above 25.1% after 1 days, however that of direct cut silage had 17.6%. And the effluent of wilted silage was decreased with prolonged wilting period, but that of direct cut silage produced effluent of 183 mL/kg. Crude protein and ether extract with wilted silage were decreased, however crude ash was increased with prolonged wilting period. Silage with pre-wilting had higher acid detergent fiber (ADF) and neutral detergent fiber (NDF) contents than control silages, while its non-fiber carbohydrate (NFC) showed the opposite results. Lactic acid and total organic acid were increased with prolonged wilting period. For the palatability of dairy goat, silage with 2 days wilting was highest among silages. The experiment results indicate that wilted sorghum$\times$sudangrass hybrid silage could be recommended as effective method for reducing effluent, increasing pH and forage quality more than direct cut silage. Optimum pre-wilting day of sorghum$\times$sudangrass hybrid silage may be 1 days.

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Effects of Probiotics as an Alternative for Antibiotics on Growth Performance, Nutrient Digestibility, Noxious Gas Emission and Fecal Microbial Population in Growing Piglets (항생제 대체 생균제가 자돈의 생산성,영양소 이용률, 유해가스 발생량 및 분내 미생물 수에 미치는 영향)

  • Kim, Jong-Duk;Chung, Heung-Woo;Shim, Kum-Seob;Park, Seung-Young;Ju, Jong-Cheol;Song, Jae-Jun;Lee, Kyung-Ho;Park, Joong-Kook;Park, Do-Yun;Kim, Chang-Hyun
    • Korean Journal of Organic Agriculture
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    • v.18 no.4
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    • pp.527-539
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    • 2010
  • This study was conducted to determine the effect of probiotics as an alternative for antibiotics on growth performance, nutrient digestibility, noxious gas emission and fecal microbial population in growing piglets. A total of 96 piglets ($22.5{\pm}1.3$kg average body weight) were allotted to 3 different treatment groups and replicated 4 times with 8 piglets per replicate in randomized complete block design. Treatments were T1) (Control, basal diet+0.2% antibiotics), T2) 0.2% probiotics complex and T3) 0.3% Bacillus probiotics. During the whole experiment period, there were no differences (p>0.05) in average daily gain (ADG), average daily feed intake (ADFI) and feed efficiency. However, digestibility of dry matter, crude protein, ether extract, nitrogen free extract and crude ash were showed higher in probiotics groups (T2 and T3) than those of control. In noxious gas emission, ammonia, amine, hydrogen sulfide and mercaptan were significantly (p<0.05) reduced in T2 and T3 treatments compared to those in control. Moisture content of feces was not significantly different among treatments. The colony forming units (CFU) of total bacteria, E. coli and thermoduric bacteria in feces were significantly different among treatments. The CFU of total bacteria, E. coli and thermoduric bacteria in T3 treatment were reduced by feeding probiotics B. From this study, we suggest that probiotics A and B are likely able to improve the growth performance and nutrients digestibility, reduce noxious gas emission and change the fecal microbial composition in growing piglets.

Effect of Grass Filter Strips on PO4-P and Soil Loss in Runoff from Forage Cropland (사료작물 재배지에서 초지식생대가 PO4-P 및 토양유실 저감에 미치는 영향)

  • Jo, Nam-Chul;Yoon, Sei-Hyung;Kim, Ki-Young;Lee, Ki-Won;Kim, Meng-Jung;Yook, Wan-Bang;Jung, Min-Woong
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.30 no.4
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    • pp.309-316
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    • 2010
  • The performance of grass filter strips (GFS) in reducing $PO_4$-P concentrations and soil loss from the forage cropland was tested in an experiment on the 10% slope in Grassland and Forages Division, National Institute of Animal Science, Rural Development Administration (RDA) from October 2007 to September 2009. Forage cropland with rye-corn double cropping system receiving inorganic fertilizer or livestock manure (LM) were compared in a natural condition. The plots were hydrologically isolated in a randomized block layout of 3 treatments $\times$ 2 factors $\times$ 3 replicates. Main plots consisted of the length of GFS, such as $25\;m^2$ ($5{\times}5\;m$), $50m^2$ ($5{\times}10\;m$), $75m^2$ ($5{\times}15\;m$). Sub plots consisted of the type of LM, such as chemical fertilizer (CF), cattle manure (CM) and swine manure (SM). Concentrations of $PO_4$-P in surface runoff water were reduced as the length of GFS increased. Especially, GFS with 10 m and 15 m reduced $PO_4$-P concentrations significantly compared to that with 0 m (p<0.05). However, there was not significant different between $PO_4$-P concentrations of GFS with 10m and that of GFS with 15 m. Moreover, Soil loss in surface runoff water were reduced as the length of GFS increased. GFS with 15 m reduced soil loss significantly compared to that with 5 m and 10 m (p<0.05). The results from this study suggest GFS improve the removal and trapping $PO_4$-P and soil loss from forage cropland.

Effect of Seeding Rates of Cold Tolerant Italian Ryegrass Varieties on Those Seed Production (내한성 이탈리안 라이그라스 품종별 파종량이 종자생산에 미치는 영향)

  • Kim, Meing-Jooung;Seo, Sung;Kim, Jong-Geun;Choi, Ki-Jun;Kim, Ki-Yong;Lee, Sang-Hoon;Chang, Sun-Sik;Kim, Tae-Il;Kwon, Eung-Gi;Jeon, Byoung-Soo;Choi, Ki-Choon
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.30 no.3
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    • pp.247-256
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    • 2010
  • This experiment was carried out to investigate the effect of seeding rate of newly developed Italian ryegrass varieties, "Kogreen" and "Hwasan 101", on those seed production in Cheonan for three years (2005 to 2007). Two Italian ryegrass varieties were seeded at experimental fields of Grassland and Forage Division, National Institute of Animal Science on late September, and harvested at seed shattering stage. The experiment was arranged in randomized complete block design with three replications by each variety. The treatments was consisted of five seeding rates (5, 10, 20, 30, 40 kg/ha). The average heading date of "Kogreen" was 9 May and "Hwasan 101" was 25 May. The harvesting date of "Kogreen" was on 16 June when the rainy season should not set in. In the case of "Hwasan 101", the harvesting date of seed production was 3 July, because of rainy season. The number of ear per square meter, ear length, spikelet number, seed yield per ha and ripening rate of "Hwasan 101" were 471, 28.5 cm, 24.8, 1,631 kg and 71%, respectively. and those of "Kogreen" were 633, 24.0 cm, 20.8, 2,676 kg and 82.1%, respectively. The shattering property rate of "Hwasan 101" 40.3% was higher than that of "Kogreen" 2.6%. The germination rate of harvested "Hwasan 101" seed was 81.8% and that of "Kogreen" was 79.4%, respectively. In conclusion, the optimum seeding rate of Italian ryegrass for seed production are recommended 20kg/ha in both "Hwasan 101" and "Kogreen".

Comparison of Growth Characteristics and Productivities of Hairy Vetch (Vicia villosa) Varieties (헤어리 베치의 품종별 생육 특성과 생산성 비교)

  • Lee, Joung-Kyong;Lim, Keun-Bal;Kim, Ki-Yong;Choi, Gi-Jun;Seong, Byung-Ryul;Seo, Sung;Ji, Hee-Chung;Choi, Yeon-Sik;Shin, Jeong-Nam;Park, Hyung-Soo
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.27 no.4
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    • pp.249-256
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    • 2007
  • This experiment was conducted to compare the agronomic characteristics and productivity in introduced hairy vetch cultivars and developed new Korean Hairy vetch cultivars in two areas of the experimental field of Grassland and Forage Crops Division, National Institute of Animal Science from 2005 to 2006. The experiment was arranged in randomized complete block design with three replications. A total of 11 hairy vetch cultivars used in this study including 9 introduced cultivars (Penn-02, Sander, Latigo, Welta, Ostsaat, VV4712, Minnie, Barlosa and Capello) and 2 Korean cultivars (Cold green and Cheong pa). The early flowering varieties of Minnie, Barlosa, Capello and Cold green were grown as early maturity cultivars, while the late flowering varieties of Penn-02, Sander, Latigo, Welta, Ostsaat, VV4712 and Cheong pa were grown as medium and late maturity. The winter hardiness of hairy vetch was good except for Minnie, Barlosa and Capello of early maturity cultivars. In this study, dry matter yield of VV4712 was the highest of 11 hairy vetch cultivars. And dry matter yield of medium and late maturity vetch increased in the middle region while that of early maturity increased in the south. The new Korean cultivar, Cheong pa, as a medium and late maturity hairy vetch was not bad compared to introduced cultivars and Cold green as an early maturity hairy vetch was an excellent cultivar compared to introduced cultivars in both regions. Latigo in NDF (neutral detergent fiber) and Welta in ADF (acid detergent fiber) were lower than other cultivars, while Sander in IVDMD (in vitro dry matter digestibility) and CP (crude protein) content were higher than other cultivars. The results of this experiment indicated that the productivity of hairy vetch cultivars was highest in VV4712, and Cheong pa and Cold green of new Korean cultivar were the promising cultivars of hairy vetch in Korea.

Effects of Mixed Application of Chemical Fertilizer with Liquid Swine Manure on Agronomic Characteristics, Yield and Feed Value of Sorghum × Sorghum Hybrid for Silage in Paddy Field Cultivation (논 토양에서 사일리지용 수수 × 수수 교잡종 재배시 화학비료와 발효 돈분 액비 혼용 시용이 생육특성 및 영양성분에 미치는 영향)

  • Hwan, Hwang Joo;Lee, Sang Moo
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.35 no.4
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    • pp.290-296
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    • 2015
  • This study was conducted to investigate the influence of the mixed application of chemical fertilizer (CF) with liquid swine manure (LSM) on the agronomic characteristics, dry matter yield, minerals, and free sugar in cultivating Sorghum ${\times}$ Sorghum Hybrid (SSH) on paddy soil. The field experiment was designed in a randomized block design with three replications and consisted of CF 100% (C), CF 70% + LSM 30% (T1), CF 50% + LSM 50% (T2), CF 30% + LSM 70% (T3), and LSM 100% treatment (T4). The application of LSM was based only on the nitrogen (150 kg/ha). Plant length, leaf length, leaf width and stem diameter were significantly the lower in T4 (p<0.05). Stem hardness increased significantly (p<0.05) as the LSM application rate decreased. Fresh yield was the highest in T2, whereas the lowest in T3 (p<0.05). However, dry matter yields and TDN yield did not show significant difference among treatments. Crude protein was the highest in T1 (p<0.05). Crude fat content did not significant differences between the T1, T2, T3 and T4, but C showed a significantly different (p<0.05). NDF and crude fiber were the highest in T3 and C, respectively (p<0.05). However, ADF did not show significant difference among treatments. Total mineral contents were higher in the order of T1> T2> T4> T3> C (p<0.05). Free sugar contents were significantly higher at T1 and C as compared to other treatments. The analysis of all the above results suggests that the application of liquid swine manure is very effective, considering the yield performance and the content of mineral and free sugar. In addition, liquid swine manure may be possible to grow SSH without chemical fertilizer.

Effects of Forage Cropping System and Cattle Slurry Application on Productivity of Rice and Forage Crops and Nutrient Movement in Paddy Land (녹비작물의 경작형태와 우분액비시용이 벼와 사료작물의 생산성 및 양분이동에 미치는 영향)

  • Yook, Wan-Bang;Choi, Ki-Choon;Lee, Kyeong-Bo;Kang, Yo-Sep;Yoon, Chang
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.31 no.1
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    • pp.55-64
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    • 2011
  • This study was conducted to investigate the effects of green manure crops and cattle slurry application on rice productivity and nutrient movement in paddy land. Cropping systems used in this study were consisted of five designs, such as mono-cropping rice applied with standard fertilizer (MRS), double-cropping whole crop barley following rice applied with cattle slurry (DWBRC), double-cropping whole crop rye following rice applied with cattle slurry (DWRRC), mono-cropping rice applied with following milk vetch (MRMV) and mono-cropping rice applied with following hairy vetch (MRHV). The field experiments were conducted on the clay loam at Backsanmyun, Kimje, Chunlabukdo province in Korea for three years (May 2006 to Apr. 2009). This study was arranged in completely randomized design with three replicates. Culm and panicle length of rice were higher in MRS than other treatments. Ripened grain ratio was higher in MRS than other treatments. Yield of Grain showed high in MRS, DWBRC and DWRRC than MRMV and MRHV. The yield of dry matter (DM) of whole crop barley in DWBRC increased significantly as compared with that of rye in DWRRC. The pH, and contents of T-N, $P_2O_5$ and organic matter (OM) and exchangeable cation (Ca, Na, Mg and K) in soil samples collected at the end of the experiment were remarkably higher than those at the beginning of the experiment. The concentrations of $NO_3$-N, $NH_4$-N and $PO_4$ in discharge water in DWBRC and DWRRC were higher than MRS.

Evaluation of Carrying Capacity for Hanwoo Heifers When Fed Whole Crop Barley and Rye as Influenced by Organic Fertilizer Application and Mixed Sowing with Legumes (유기질비료 시용과 두과 사료작물의 혼파에 따른 청보리와 호밀의 생산성과 단위면적당 한우 사육능력 추정)

  • Jo, Ik-Hwan
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.32 no.2
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    • pp.117-124
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    • 2012
  • This study was conducted to estimate Hanwoo carrying capacity when whole crop barley or rye as winter forage crops was grown on different applying sources (chemical fertilizer, cattle or organic fertilizer) and mixed sowing combination with hairy vetch or forage pea during the period of 2008~2010. The experimental plots within whole crop barley or rye were consisted of 7 treatments, which were non-fertilizer, chemical fertilizer (P+K), chemical fertilizer (N+P+K), organic fertilizer, cattle slurry, cattle slurry with hairy vetch, and cattle slurry with forage pea. Each plot was triplicates and experimental treatments were allocated in the randomized complete block design. For whole crop barley, annual mean dry matter (DM) and total digestible nutrients (TDN) yields were the highest in N+P+K plots, but there were no significant differences among organic fertilizer, cattle slurry and mixed sowing with legumes. The TDN and RFV were the highest in mixed sowing plots of forage pea plus cattle slurry application. As 450 kg Hanwoo heifers were fed diets included 70% whole crop barley, organic fertilizer, cattle slurry application and mixed sowing with legumes plots is capable of raising average 2.5 to 2.9 heads/ha a year. For whole crop rye, annual DM, crude protein, and TDN yields of application groups and mixed sowing treatment with legumes showed 6.69~7.13, 0.46~0.51 and 3.95~4.18 ton/ha, respectively. In case of 450 kg Hanwoo heifers fed diets included 70% forage rye, it is estimated that cattle slurry application (mixed sowing with legumes) plots can rear average 3.1~3.3 heads/ha a year. It can be concluded that, on the basis of DM yield, not only mixed sowing with legumes by applying cattle slurry rather than single sowing of whole crop barley or whole crop rye enhanced production yield and feed values, but also it could be a substitute for imported grains as dietary protein sources in the case of feeding Hanwoo.

The Test of Combining Ability and Heterosis on the Silkworm(Bombyx mori) Breeding (누에 견.사질에 관한 잡종강세 및 조합능력검정)

  • 문병원;한경수
    • Journal of Sericultural and Entomological Science
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    • v.36 no.1
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    • pp.8-25
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    • 1994
  • The study was conducted to obtain the genetic information on heterosis and combining ability of the quantitative characters for F1 hybrid breeding in silkworms. Six parental varieties and each set of 30 diallel crosses in F1's were used as materials, and bred on the randomized complete block design with three replications. Fourteen characters were observed with the twenty samples in each tray. The data were analyzed for (1) heterosis and combining ability in F1 hybrid. The heterosis in the weight and the length of cocoon showed positively high at 24.51%, and 23.4%, respectively and the weight of the whole cocoon as well as the weight of the whole cocoon layer showed a siginificant heterosis ranging from 15.56% to 15.71% and from 17.14% to 19.01%, but the fifth and the total instar period showed negative heterosis. It was found that the combination between, C70XRomogua and N9 X Romogua showed highly a negative heterosis on the fifth instar period and for the cocoon weight. The female of N9+Sansuian and the male of Romogua X Sansurian have a high heterosis effect, on the cocoon shell weight, and Sansurian X Romogua(reciprocal) on the length and the weight of cocoon filament with no regard to sexuality. The significant maternal and cytoplasmic effect on heterosis of the cocoon weight and the cocoon shell weight were observed with the combinations, N9 X C5, N63 X C70 and on the length of the cocoon filament with the combinations, Sansurian X N63, Sansurian X C5, Sansurian X C70 and N9 X C70, N63 X C70 on the weight of cocoon filament. As mean squared of GCA, SCA and RCA were significant with these combining ability for all characters resulted from additive and non-additive altogether and there is a significant difference between reciprocals. Sansurian showed a negative GCA effect on the fifth and total larval duration, but the higher positive GCA effects took places with varieties N9 and C5 on the length, width, weight of cocoon, cocoon shell weight, percentage of cocoon shell weight, length and weight of cocoon filament, percentage of raw-silk with no regard to both generations and silkworm sexuality. The values of SCA between the cross combinations varied generation-wise and sex-wise. It was shown that SCA value for the fifth instar period was highly negative for Sansurian X C70, Romogua X C70, Sansurian X C5, Romogua X C5, but it was positive effect on the cocoon weight, cocoon shell weight with N9 X C5, and C70 X Sansurian, on the length of cocoon filament with N9 X C5, Romogua X Sansurian on the weight of cocoon filament between Romogua and N63 and on the percentage of raw-silk between the combination of Sansurian X Romoga.

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