• Title/Summary/Keyword: Raman Analysis

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A screening of Alzheimer's disease using basis synthesis by singular value decomposition from Raman spectra of platelet (혈소판 라만 스펙트럼에서 특이값 분해에 의한 기저 합성을 통한 알츠하이머병 검출)

  • Park, Aaron;Baek, Sung-June
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.5
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    • pp.2393-2399
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    • 2013
  • In this paper, we proposed a method to screening of Alzheimer's disease (AD) from Raman spectra of platelet with synthesis of basis spectra using singular value decomposition (SVD). Raman spectra of platelet from AD transgenic mice are preprocessed with denoising, removal background and normalization method. The column vectors of each data matrix consist of Raman spectrum of AD and normal (NR). The matrix is factorized using SVD algorithm and then the basis spectra of AD and NR are determined by 12 column vectors of each matrix. The classification process is completed by select the class that minimized the root-mean-square error between the validation spectrum and the linear synthesized spectrum of the basis spectra. According to the experiments involving 278 Raman spectra, the proposed method gave about 97.6% classification rate, which is better performance about 6.1% than multi-layer perceptron (MLP) with extracted features using principle components analysis (PCA). The results show that the basis spectra using SVD is well suited for the diagnosis of AD by Raman spectra from platelet.

The Study on Characteristics of a-C:H Films Deposited by ECR Plasma (전자회전공명 플라즈마를 이용한 a-C:H 박막의 특성 연구)

  • 김인수;장익훈;손영호
    • Proceedings of the Korea Society for Industrial Systems Conference
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    • 2001.05a
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    • pp.224-231
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    • 2001
  • Hydrogenated amorphous carbon films were deposited by ERC-PECVD with deposition conditions, such as ECR power, gas composition of methane and hydrogen, deposition time, and substrate bias voltage. The characteristics of the film were analyzed using the AES, ERDA, FTIR. Raman spectroscopy and micro hardness tester. From the results of AES and ERDA, the elements in the deposited film were confirmed as carbon and hydrogen atoms. FTIR spectroscopy analysis shows that the atomic bonding structure of a-C:H film consisted of sp³and sp²bonding, most of which is composed of sp³bonding. The structure of the a-C:H films changed from CH₃bonding to CH₂or CH bonding as deposition time increased. We also found that the amount of dehydrogenation in a-C:H films was increased as the bias voltage increased. Raman scattering analysis shows that integrated intensity ratio (I/sub D//I/sub G/) of the D and G peak was increased as the substrate bias voltage increased, and films hardness was increased.

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Design of Fuzzy Clustering-based Neural Networks Classifier for Sorting Black Plastics with the Aid of Raman Spectroscopy (라만분광법에 의한 흑색 플라스틱 선별을 위한 퍼지 클러스터링기반 신경회로망 분류기 설계)

  • Kim, Eun-Hu;Bae, Jong-Soo;Oh, Sung-Kwun
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.66 no.7
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    • pp.1131-1140
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    • 2017
  • This study is concerned with a design methodology of optimized fuzzy clustering-based neural network classifier for classifying black plastic. Since the amount of waste plastic is increased every year, the technique for recycling waste plastic is getting more attention. The proposed classifier is on a basis of architecture of radial basis function neural network. The hidden layer of the proposed classifier is composed to FCM clustering instead of activation functions, while connection weights are formed as the linear functions and their coefficients are estimated by the local least squares estimator (LLSE)-based learning. Because the raw dataset collected from Raman spectroscopy include high-dimensional variables over about three thousands, principal component analysis(PCA) is applied for the dimensional reduction. In addition, artificial bee colony(ABC), which is one of the evolutionary algorithm, is used in order to identify the architecture and parameters of the proposed network. In experiment, the proposed classifier sorts the three kinds of plastics which is the most largely discharged in the real world. The effectiveness of the proposed classifier is proved through a comparison of performance between dataset obtained from chemical analysis and entire dataset extracted directly from Raman spectroscopy.

Vapor Phase Deposition and Characterization of Diamond Thin Films on Refractory Metals (내열금속 기판위에 다이아몬드 박막의 증착과 특성분석)

  • 홍성현;형준호
    • Korean Journal of Crystallography
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    • v.5 no.1
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    • pp.39-50
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    • 1994
  • Diamond thin films were deposited on silicon, molybdebum, titanum and tugsten substrates, and were chlwntnizen using scanning electron microscopy, X-ray diffraction analysis and Raman spectroscopy. From the result of experiment in various deposition periods, it was found that found that were nucleated and grown on interlayed carbide layers, which were formed on refractory metal substrates at the initial stage of.

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Confocal Raman Spectrum Classification Using Fisher Measure based Filtering for Basal Cell Carcinoma Detection (기저세포암종 탐지를 위한 피셔척도 필터링 기반 공초점 라만 스펙트럼 분류)

  • Min So-Hui;Kim Jin-Yeong;Baek Seong-Jun;Na Seung-Yu;Ju Jae-Beom
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2006.05a
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    • pp.203-207
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    • 2006
  • This paper deals with a problem of detecting BCC using confocal raman spectrum. Specially, we propose Fisher measure based filtering for rejection of frequency components being noisy or non-discriminative. we use PCA (principal component analysis) for reduction of feature space dimension. Also, we apply MAP detector for classification of BCC raman spectrum. The experimental results shows that our proposed method can reduce the feature dimension and also raise the detection ratio.

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Wide Field Imaging Analysis of Graphene (그래핀의 대면적 이미지 특성 분석)

  • Kwon, Kanghyuk;Kim, Nayoung;Havener, Robin W.;Won, Donggwan;Cho, Seungmin;Park, Jiwoong
    • Korean Journal of Optics and Photonics
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    • v.24 no.3
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    • pp.143-147
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    • 2013
  • A Raman spectrometer is essential for analyzing the characteristics of graphene. The commercial micro-Raman spectrometer is useful for measuring small areas, but due to the small measuring area, it has limited use in industry, as a sampling measure. This paper suggests a Raman spectrometer able to get a large area image of graphene. By using this image, we can get information on defects and on the presence of graphene. Therefore, this equipment can be used for quality assessment for production of graphene.

Fourier Transform Raman Studies of Methyl Red Adsorbed on γ-Alumina and Silica-Alumina

  • Park, Sun-Kyung;Lee, Choong-Keun;Min, Kyung-Chul;Lee, Nam-Soo
    • Bulletin of the Korean Chemical Society
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    • v.25 no.12
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    • pp.1817-1821
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    • 2004
  • Fourier transform Raman spectra of methyl red adsorbed on untreated and pretreated ${\gamma}$-alumina and silicaalumina calcined at 900 $^{\circ}C$ under 1 atm steam flowing were recorded. Spectral analysis shows that the active species adsorbed on ${\gamma}$-alumina was to be deprotonated methyl red, and on silica-alumina to be di-protonated. This indicates that ${\gamma}$-alumina adapted in this work holds Bronsted basicity, and silica-alumina Bronsted acidity. Raman intensities of methyl red on pretreated ${\gamma}$-alumina are about three times stronger than on untreated ${\gamma}$-alumina, while spectral features are unchanged. For silica-alumina, spectral features show modified vibrational characteristics upon surface hydroxylations generated from pretreatment. Consequently, the acidity loss for silica-alumina and the basicity gain for ${\gamma}$-alumina were observed by increasing the surface hydroxyl groups on the catalysts through pretreatment of the steam calcination.

Simulation of Amplification Characteristics of Ultrashort Laser Pulse Amplification using Raman Backscattering (라만 후방향 산란을 이용한 레이저 펄스 증폭에서 나타나는 증폭 특성의 시뮬레이션)

  • Kim, Jincheol;Lee, Hae-June;Kim, Guang-Hoon;Kim, Changbum;Kim, Jong-Uk;Hyyong Suk
    • Proceedings of the Optical Society of Korea Conference
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    • 2002.07a
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    • pp.230-231
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    • 2002
  • Recently, analysis of transient Raman backscattering in a plasma reported(2.3) that it is possible to reach 10$\^$17/ W/cm$^2$ for 1 micrometer wavelength laser pulse with a counter-propagating pump pulse. The basic mechanism is like this : whorl the two counter-propagating waves in a plasma satisfy the condition of Raman backscattering, w$\_$0/ : w$\_$1/ + w$\_$p/, energy is transferred from the long pulse to the short pulse via three wave interaction(4). (omitted)

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Structural Analysis of $Na_2O$-$Ga_2O_3$-$SiO_2$ System Glasses by FT-IR and Raman Spectroscopy (FT-IR 및 Raman 분광법에 의한 $Na_2O$-$Ga_2O_3$-$SiO_2$ 계 유리의 구조분석)

  • Whang, Chin-Myung;Rhee, Jhun;Bae, In-Kook
    • Journal of the Korean Ceramic Society
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    • v.25 no.1
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    • pp.27-34
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    • 1988
  • In order to investigate the reason of changes in the physical properties of glasses near the region for which R(Ga/Na)=1, spectroscopic studies using FT-IR and Raman spectroscopy have been carried out on Na2O.2SiO2 glass with addition of Ga2O3 from 0 to 35 mole %, i.e., from R=0 to 1.61. The main purpose of this work is to investigate the coordination number of Ga3+ in glass with variation of glass composition and to determine the existence of tricluster in the Ga-rich region for which R>1.0 in Na2O-Ga2O3-SiO2 system.

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A Study on the Structural Characteristics of PLZT Thin Films with Zr/Ti Ratios Prepared by Sol-Gel Method (Sol-Gel 법으로 제작된 PLZT 박막의 Zr/Ti 비에 따른 구조 특성에 관한 연구)

  • ;;J. Dougherty
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.11 no.7
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    • pp.535-540
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    • 1998
  • Thin films of PLZT were prepared on indium tin oxide(ITO) coated glass substrates by sol-gel process and annealed by rapid thermal annealing(RTA) at $750^{\circ}C$ for 5 minutes. The crystal structure of PLZT thin films were investigated for a different Zr mol% content. XRD results showed that the crystallographic structure was transitted from tetragonal to rhombohedral structure as Zr mol% increased. Raman spectroscopy results showed that the bands of spectra became broader as the amount of Zr mol% increased and two crystal phase coexisted at 2/55/45 PLZT film. Raman spectroscopy was useful for crystal structure analysis of PLZT thin films.

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