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Literature Review on Safety of Pharmacopuncture according to Sasang Constitutional Medicine (동의수세보원(東醫壽世保元) 신정(新定) 처방(處方) 약재(藥材)의 약침 안전성 문헌 조사)

  • Oh, Seung-Yun;Kim, Koo;Kwon, Young-Mi;Lee, Si-Woo;Jang, Eun-Su;Joo, Jong-Cheon
    • Journal of Sasang Constitutional Medicine
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    • v.23 no.1
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    • pp.79-86
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    • 2011
  • 1. Objectives: Pharmacopuncture according to Sasang Constitutional Medicine is new field of constitutional medicine. We investigated safety of pharmacopunctures to develop this treatment. 2. Methods: We searched for papers in fifteen Korean oriental medical journals and four online searching portal articles. Hepatotoxicity, nephrotoxicity and general toxicity tests were investigated about one hundred thirty kinds of pharmacopunctures. 3. Results: Toxicity test about 36 kinds of 130 pharmacopunctures were investigated. 1) Hepatotoxicity and nephrotoxicity test of pharmacopunctures were searched in 11 of 38 Soeumin herbs, 8 of 36 Soyangin herbs, 5 of 44 Taeeumin herbs and 1 of 12 Taeyangin herbs. From among these herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Fructus alpiniae oxyphyllae(益智仁), Semen crotonis(巴豆), Radix bupleuri(柴胡) and Semen armeniacae amarum(杏仁) pharmacopunctures. 2) General toxicity test of pharmacopunctures were searched in 8 of 38 Soeumin herbs, 9 of 36 Soyangin herbs, 6 of 44 Taeeumin herbs and 2 of 12 Taeyangin herbs. from among thes herbs, toxicity was detected in Radix aconiti lateralis preparata(附子), Radix ginseng(人蔘), Semen crotonis(巴豆), Rhizoma seu radix notopterygii(羌活), Radix aralia cordatae(獨活), Semen armeniacae amarum(杏仁) and Radix scutellariae(黃芩) and Cortex acanthopanacis(五加皮) pharmacopunctures. 4. Conclusions: From these results, we must decide extraction method, concentration and dose carefully to use the toxic pharmacopuncture. More toxicity test and further study is needed about pharmacopuncture treatment in Sasang Constitutional Medicine.

A New DIT Radix-4 FFT Structure and Implementation (새로운 DIT Radix-4 FFT 구조 및 구현)

  • Jang, Young-Beom;Lee, Sang-Woo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.1
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    • pp.683-690
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    • 2015
  • Two basic FFT(Fast Fourier Transform) algorithms are the DIT(Decimation-In-Time) and the DIF (Decimation-In-Frequency). In spite of the advantage of the DIT algorithm is to generate a sequential output, various structures have not been made. In this paper, a new DIT Radix-4 FFT butterfly structure are proposed and implemented using Verilog coding. Through synthesis, it is shown that the 64-point FFT is implemented by 6.78 million gates. Since the proposed FFT structure has the advantage of a sequential output, it can be used in OFDM communication SoC(System on a Chip) which need a high speed FFT output.

Antioxidative Properties and Whitening Effects of the Astragali Radix, Atractylodis Rhizoma Alba and Acanthopanacis Cortex (황기, 백출 및 오가피의 항산화성 및 미백효과에 관한 연구)

  • Kim, Il-Chool;Hur, Sang-Sun
    • Journal of the Korean Applied Science and Technology
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    • v.26 no.2
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    • pp.110-116
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    • 2009
  • In an attempt to find natural sources of antioxidants and whitening agents, Comparisons of the antioxidative and tyrosinase inhibitory activities of various ethanol extracts of Astragali Radix, Atractylodis Rhizoma Alba and Acanthopanacis Cortex were carried out. Comparison of the four ethanol extracts revealed that, Astragali Radix had the highest electron-donating ability(72.5%) and the highest SOD-like ability(26.1%). The xanthine oxidase experiment exhibited a hindrance effect of 88.5% in Atractylodis Rhizoma Alba, 81.1% in Acanthopanacis Cortex, 75.8% in Astragali Radix. A tyrosinase inhibitory activity assay was conducted to evaluate the whitening effects of the extracts, The tyrosinase inhibitory activity was 42.1% in the Acanthopanacis Cortex, 37.2% in the Atractylodis Rhizoma Alba, 6.0% in the Astragali Radix. Based on these results, we suggest that the ethanol extracts of Astragali Radix, Atractylodis Rhizoma Alba and Acanthopanacis Cortex can be used as food and cosmetic ingredients.

Literatural Study on the cause of a disease and prescription in migraine (편두통(偏頭痛)의 원인(原因)과 처방(處方)에 대한 문헌적(文獻的) 고찰(考察))

  • Kim, Jong-In;Hwang, Chi-Won
    • Journal of Haehwa Medicine
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    • v.8 no.2
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    • pp.171-189
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    • 2000
  • By Literatural studying on migraine, The results were obtained as fallow : 1. A different name on migraine were called hemicrania(頭偏痛, 邊頭痛, 偏頭風). 2. In the cause of a disease in migraine, the cases were clasified into the fallowing kind : internal cause were a decline in energy and blood(氣血具虛), external cause were outside evil(外邪) in wind cold heat wetness(風寒暑濕), non internal, external cause were exhaustion. The right side migraine were concerned phlegm heat, the right side migraine were concerned wind decline in blood. 3. Migraine is appeared on the side, For the reason, liver function in excess of normal limits(肝陽上亢), a sudden of liver fire(肝火) is becomeed of invasion upon soyangkuong(少陽經) in internal external cause 4. Usage method of medicines is appeared that order underclothes theraphy(內服法), to pump out in nose theraphy, to join head theraphy(頭點法), heating smoke theraphy(熏煙法) 5. CNIDII RHIZOMA(川芎) is in mostly general use for migraine, in that order LEDEBOURIELLAE RADIX(防風) ANGELICAE DAHURICAE RADIX(白芷) ASARI HERBA CUM RADICE(細辛) NOTOPTERYGII RHIZOMA(羌活) GLYCYRRHIZAE RADIX(甘草) CHRYSANTHEMI FLOS(菊花) BUPLEURI RADIX(柴胡) SCUTELLARIAE RADIX(黃芩) ANGELICAE GIGANTIS RADIX(當歸) GYPSUM FIBROSUM(石膏) MENTHAE HERBA(薄荷) GLYCYRRHIZAE RADIX(炙甘草) VITICIS FRUCTUS(蔓荊子), nature is in mostly general hot warm(辛溫), bitter cold(苦寒), guikuong(歸經) is in mostly general liver gall kuong(肝膽經), efficacy is in mostly general to remove wind pain (祛風止痛) and to down fire(瀉火).

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Antioxidative Properties and Whitening Effects of the Cuscutae Semen, Rubi Fructus and Paeoniae Radix (토사자, 복분자 및 작약의 항산화성 및 미백효과에 관한 연구)

  • Hur, Sang-Sun;Kim, Il-Chool
    • Journal of the Korean Applied Science and Technology
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    • v.31 no.1
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    • pp.136-142
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    • 2014
  • In an attempt to find natural sources of antioxidants and whitening agents, comparisons of the antioxidative and tyrosinase inhibitory activities of various ethanol extracts of Cuscutae Semen, Rubi Fructus and Paeoniae Radix were carried out. Comparison of the three ethanol extracts revealed that, Paeoniae Radix had the highest electron-donating ability(79.3%),; however, Rubi Fructus had the highest SOD-like ability(31.1%). The xanthine oxidase experiment exhibited a hindrance effect of 74.3% in Cuscutae Semen, 80.4% in Rubi Fructus and 60.8% in Paeoniae Radix. A tyrosinase inhibitory activity assay was conducted to evaluate the whitening effects of the extracts, The tyrosinase inhibitory activity was 20.1% in the Cuscutae Semen, 54.2% in the Rubi Fructus, 56.3% in the Paeoniae Radix. Based on these results, we suggest that the ethanol extracts of Cuscutae Semen, Rubi Fructus and Paeoniae Radix can be used as food and cosmetic ingredients.

In Vitro Inhibitory Effect of Triterpenoidal Saponins from Platycodi Radix on Pancreatic Lipase

  • Xu Bao Jun;Han Li Kun;Zheng Yi Nan;Lee Jeong Hyun;Sung Chang Keun
    • Archives of Pharmacal Research
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    • v.28 no.2
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    • pp.180-185
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    • 2005
  • In the process of investigating anti-obesity effect of Platycodi Radix, we found that aqueous extract of Platycodi Radix might inhibit intestinal absorption of dietary fat by inhibiting pancreatic lipase (PL) activity. In order to clarify the anti-obesity mechanism of Platycodi Radix, activity-guided isolation was performed to find active components. The total saponin fraction of Platycodi Radix appeared to have a potent inhibitory activity against the hydrolysis of triolein emulsified with phosphatidycholine by pancreatic lipase in vitro. Based on these results, further purification of active components yielded 10 known triterpenoidal saponins, among these compounds, platycodin A, C, D, and deapioplatycodin D exhibited significant inhibitory effects on PL at the concentration of $500\;{\mu}g/mL$ with 3.3, 5.2, 34.8, and $11.67\%$ pancreatic lipase activity vs control, respectively. Platycodin D was found to inhibit the PL activity in a dose-dependent manner. Therefore, the anti-obesity effect of Platycodi Radix might be due to the inhibition of pancreatic lipase by its saponins.

A Comparative Study on the Solvent Extraction and Supercritical Fluid Extration Method of ${\beta}-Ecdysone$ in Achyranthis radix (우슬 중 ${\beta}-Ecdysone$의 초임계추출법(SFE)과 용매추출법의 비교)

  • Kim, Mi-Ra;Kim, Myong-Seok;Shim, Jae-Han
    • Applied Biological Chemistry
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    • v.44 no.3
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    • pp.197-201
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    • 2001
  • Extraction efficiency of ${\beta}-ecdysone$ in Achyranthis radix was investigated using the methods of solvent extraction and supercritical fluid extraction (SFE). The optimum SFE conditions for the analysis of ${\beta}-ecdysone$ in A. radix were 300 atm, $80^{\circ}C$, 100 ml of extraction volume, and 20% ratio of modifier(methanol). As revealed through SFE, detection limit of ${\beta}-ecdysone$ in A. radix was 5 ng and recoveries of ${\beta}-ecdysone$ in A. radix shoots and root were $90.7{\sim}93.5%$ and $77.8{\sim}81.9%$, respectively. Recoveries of ${\beta}-ecdysone$ in A. radix shoots and root through solvent extraction were $76.4{\sim}93.0%$ and $80.6{\sim}93.1%$, respectively. ${\beta}-Ecdysone$ content was determined to be highest at 654.9 ppm in the first year A. radix roots harvested in August.

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A study on the multicasting algorithm for radix-2 tree ATM switch (Radix-2 트리 ATM 스위치를 위한 멀티캐스팅 알고리즘에 관한 연구)

  • 김홍열;임제택
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.34S no.1
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    • pp.1-8
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    • 1997
  • A wide class of networking application services, such as video teleconferencing, VOD, LAN bridging, and distributed data processing require multipoint communications. The essential component inteh network to achieve this is a multicast packet switch which is capable of packet replication and switching. In this paper, we propose an efficient mukticast addressing scheme using the smallest number of routing bits which is deterministic lower bound. The new scheme performs all point-to-multipoint connection in radix-2 tree ATM switch like banyan network. Also, we provide a simple radix-2 switch block diagram for achieving our algorithm. And we investigate several addressing schemes for implementing multicasting in radix-r tree ATM switch and evaluate several performance factors, such as complexity of the additional header bits, requirement of the internal speedup and complexity of the major hardware.

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Antioxidative Properties and Whitening Effects of the Polygoni Multiflori Radix, Polygonati Rhizoma and Ephedrae Herba (하수오, 황정 및 마황의 항산화성 및 미백효과)

  • Kim, Il-Chool
    • Journal of the Korean Applied Science and Technology
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    • v.25 no.4
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    • pp.533-538
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    • 2008
  • In order to fine antioxidant and whitening agent source from nature, the comparisons of antioxidative activity and tyrosinase inhibitory activity were carried out for various ethanol extract on Polygoni Multiflori Radix, Polygonati Rhizoma and Ephedrae Herba. Comparing for three ethanol extracts, the highest electron donating ability was found at Polygonati Rhizoma (86.6%), but, the highest SOD-like ability, at the Ephedrae Herba (47.8%). Xanthine oxidase experiment exhibited 95.7% of hindrance effect in Ephedrae Herba, and 84.0% in Polygonati Rhizoma. A tyrosinase inhibitory activity assay was conducted to evaluate the whitening effects of the extracts, The tyrosinase inhibitory activity was 6.5% in the Polygoni Multiflori Radix, 32.6% in the Polygonati Rhizoma, 64.0% in the Ephedrae Herba. Based on these results, we suggest that the ethanol extracts of Polygoni Multiflori Radix, Polygonati Rhizoma and Ephedrae Herba can be used as food and cosmetic ingredients.

Review of Clinical Trials about Herbal Medicine for Vascular Dementia (혈관성 치매 치료 한약물 임상연구 고찰)

  • Kim, Ka-Na;Cho, Seung-Hun
    • Journal of Oriental Neuropsychiatry
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    • v.23 no.4
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    • pp.37-48
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    • 2012
  • Objectives : The purpose of this study is to investigate the frequently used herbal materials among herbal prescription for vascular dementia. Methods : Every article relevant to vascular dementia was initially obtained from a Korean database and PubMed. Keywords searched were 'vascular dementia', 'herbal medicine' and 'human'. Results : Clinical study, which vascular dementia were treated with herbal medicine, were 12. Among these 12 articles, 6 were case study, 1 was Controlled Clinical Trial and 5 were Ramdomized Controlled Trial (RCT). High frequently used herbal materials were Ginseng Radix (9 times), Cnidii Rhizoma (8 times), Glycyrrhizae Radix, Citri Pericarpium, Astragali Radix and Angelicae Gigantis Radix (6 times). Conclusions : We could know frequent-used herbal medicine for vascular dementia. To be aware of the frequently used herbal medicine for vascular dementia can be helpful in adding herbal materials to prescription in a clinical treatment and development of new drugs.