• 대한방사선기술학회지:방사선기술과학
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• 제33권4호
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• pp.321-326
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• 2010

본 연구에서는 미역이나 다시마에 많이 분포하면서 항산화작용이 탁월한 알긴산올리고당의 방사선 방어효과를 알아보기 위해 3 Gy 방사선이 전신 1회 조사된 마우스를 가지고 IL-6을 측정하였다. 측정 결과 방사선조사대조군과 비교하여 볼 때 소장과 간 조직 모두 방사선조사 전 7일간 알긴산올리고당의 처치를 시행한 그룹에서 IL-6 생성이 억제됨을 관찰하였다(p < 0.001). 이는 알긴산올리고당이 항산화작용을 통해 방사선이 피폭된 생체조직을 방어함으로써 IL-6의 생성을 억제한 것으로 사료된다. 결론적으로, 본 연구를 통해 알긴산올리고당의 일부 방사선 방어효과를 규명했고 아울러 화학적 독성이 없는 자연산생물이 방사선 방어제로 활용될 수 있을 가능성을 확인하였다.

• Journal of Radiation Protection and Research
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• 제9권2호
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• pp.118-128
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• 1984

1978년(年) 4월(月) 29일(日) 상업운전을 개시한 원자력(原子力) 1 호기(號機)의 방사선관리실태放射線管理實態)를 방사선피폭(放射線被爆), 방사성폐기물(放射性廢棄物) 및 환경관리(環境管理)로 구분고찰(區分考察) 하였다. 그 결과(結果) 방사선피폭(放射線被爆)과 방사성폐기물(放射性廢棄物)은 발전소(發電所) 운전년수(運轉年數)에 따라 점차(漸次) 증가현상(增加現象)을 나타내더니, 1983 및 1982 년도(年度)를 정점(頂點)으로 감소(減少) 또는 안정추세(安定趨勢)를 나타냈다. 그리고 발전소 가동후(稼動後)의 주변환경방사능(周邊環境放射能)도 발전소 가동전(稼動煎)보다 높지 않은것으로 나타났다.

• Journal of Radiation Protection and Research
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• 제30권4호
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• pp.197-208
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• 2005

Although little information is available on the underlying mechanisms, various genetic factors have been associated with tissue-specific responses to radiation. In the present study, we explored the possibility whether organ specific gene expression is associated with radiosensitivity using samples from brain, lung and spleen. We examined intrinsic expression pattern of 23 genes in the organs by semi-quantitative RT-PCR method using both male and female C57BL/6 mice. Expression of p53 and p21, well known factors for governing sensitivity to radiation or chemotherapeutic agents, was not different among the organ types. Both higher expression of sialyltransferase, delta7-sterol reductase, leptin receptor splice variant form 12.1, and Cu/Zn superoxide dismutase (SOD) and lower expression of alphaB crystalline were specific for spleen tissue. Expression level of glutathione peroxidase and APO-1 cell surface antigen gene in lung tissue was high, while that of Na, K-ATPase alpha-subunit, Cu/ZnSOD, and cyclin G was low. Brain, radioresistant organ, showed higher expressions of Na, K-ATPase-subunit, cyclin G, and nucleolar protein hNop56 and lower expression of delta7-sterol reductase. The result revealed a potential correlation between gene expression patterns and organ sensitivity, and Identified genes which might be responsible for organ sensitivity.

• Journal of Radiation Protection and Research
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• 제39권2호
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• pp.96-102
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• 2014

소변시료 바이오어세이는 분석설비가 비교적 간단하고 시료 채취가 용이하여 내부피폭선량 평가를 위하여 널리 사용되고 있는 대표적인 간접측정법이다. 본 연구에서는 소변시료 바이오어세이 결과에 대해 보다 객관적인 성능검사를 수행하기 위하여 미국 NIST에서 주관한 NRIP (NIST raiochemistry inercomparison pogram)에 참여한 결과를 소개하였다. 60일간의 분석기간 동안 인공합성소변으로 제작된 검사시료의 방사능분석결과를 보고하는 cstomary exercise에서는 12가지 방사성핵종에 대한 측정 결과 ANSI N13.30에서 제시하는 성능검사 기준을 모두 만족하는 것으로 확인되었다. 비상상황에 대비하여 8시간 이내에 방사능분석결과를 신속하게 보고하는 eergency preparedness exercise에서는 9가지 방사성핵종에 대하여 -35 ~ 45%의 차이를 나타내어 확인된 오차범위 내에서 비상시 신속한 내부피폭 분류에 적용하기에 적합한 것으로 확인되었다.

• Journal of Radiation Protection and Research
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• 제31권3호
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• pp.115-122
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• 2006

We have screened the cytoprotective effect on $\gamma$-ray radiation induced oxidative stress from eighteen Korean plant extracts. Querus salicina, Clerodendron trichotomum, Lamium amplexicaule, Lozoste lancifolia and Malus baccata were found to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and intracellular reactive oxygen species (ROS). As a result, extracts of these plants reduced cell death of Chinese hamster lung fibroblast (V79-4) cells induced by $H_2O_2$ treatment. In addition, these extracts protected cell death of V79-4 cells damaged by $\gamma$-ray radiation. In addition, these extracts scavenged ROS generated by radiation. Taken together, the results suggest that Quercus salicina, Clerodendron trichotomum, Lamium amplexicaule, Lozoste lancifolia and Malus baccata protect V79-4 cells against oxidative damage by radiation through scavenging ROS.

• 대한방사선기술학회지:방사선기술과학
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• 제47권3호
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• pp.213-218
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• 2024

The myocardial nuclear medicine examination is widely performed to diagnose myocardium disease using various radionuclides. Although image quality according to radionuclides has improved, the radiation exposure for target organ as well as peripheral organs should be considered. Here, the aim of this study was to evaluate absorbed dose (Gy) for peripheral organs in myocardial nuclear medicine scan from myocardium according to various scan environments based on Monte Carlo simulation. The simulation environment was modeled 5 cases, which were considered by radionuclides, number of injections, and radiodosage. In addition, the each radionuclide simulation such as distribution fraction was considered by recommended standard protocol, and the mesh computational female phantom, which is provided by International Commission on Radiological Protection (ICRP) 145, was used using the particle and heavy ion transport code system (PHITS) version 3.33. Based on the results, the closer to the myocardium, the higher the absorbed dose values. In addition, application for dual injection for radionuclides leaded to high absorbed dose compared with single injection for radionuclide. Consequently, there is difference for absorbed dose according to radionuclides, number of injections, and radiodosage. To detect the accurate diseased area, acquisition for improved image quality is crucial process by injecting radionuclides, however, we need to consider absorbed dose both target and peripheral inner organs from radionuclides in terms radiation protection for patient.

• 대한방사선기술학회지:방사선기술과학
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• 제42권6호
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• pp.461-467
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• 2019

The purpose of this study was to investigate the knowledge, attitudes and behaviors of radiation protection in operating room and intensive care unit nurses. The Participants for this study consisted of 240 nurses working in operating rooms and intensive care units of 7 general hospitals located in Busan, South Korea. The data were collected from Feb. 15 to Feb. 29, 2016. The study results were as follows. First, 72.9% of the nurses had never been educated for radiation safety. Second, the mean score of knowledge for radiation protection was 9.21. The knowledge score of radiation safety educated nurses is higher than uneducated of nurses(t=-5.67, p<.001). Third, The mean score of attitude towards radiation protection was 41.80. The attitude score of radiation safety educated nurses is lower than uneducated of nurses(t=0.02, p<.030). Fourth, the mean score of behavior for radiation protection was 32.57. The behavior score of radiation safety educated nurses is higher than uneducated of nurses(t=0.35, p=.001). Consequently, it was found that nurses had lack of the radiation safety education. Overall knowledge and behavior towards radiation protection was low. Therefore, it is necessary to raise awareness of radiation protection and to educate, manage, and improve processes to increasing compliance with protective measures against radiation.

• Journal of Radiation Protection and Research
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• 제27권2호
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• pp.89-94
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• 2002

IAEA 안전시리즈 109에 제시된 정당화 및 최적화 절차에 따른 비용-이득 접근법을 적용하여 우리나라에 적합한 방사선비상시 식품섭취제한 개입준위 값을 제안하였다. 관심 핵종은 예탁유효선량 기여도를 고려하여 세 그룹으로 구분하였고 대상식품은 가격에 따라 두 그룹으로 분류하였다. 아울러 제안된 개입준위를 실제 상황에 적용함에 있어서 고려해야할 사항에 대해 논의하였다.

• Journal of Radiation Protection and Research
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• 제35권3호
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• pp.99-104
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• 2010

The potential ability of environmental temperature to enhance the effect of microwave radiation (7 GHz) was experimentally studied for rabbit heating after simultaneous application of both agents. The tested ambient temperatures (30 and $38^{\circ}C$) didn't exert a considerable influence upon rabbit heat homeostasis after the used duration of exposure (3 hours and 15 minutes, correspondingly). The synergistic interaction of microwave irradiation and ambient temperature was demonstrated for rabbit heating. Power flux density of microwave irradiation was shown to be a determinant of the synergistic interaction effectiveness. For the fixed ambient temperature ($30^{\circ}C$), the synergism was shown to be observed only within a definite power flux density ($0-100\;mW{\cdot}cm^{-2}$), inside of which there was an optimal intensity ($20\;mW{\cdot}cm^{-2}$), which maximized the synergistic effect. Any deviation of the power flux density from the optimal value resulted in a reduction of the synergy. It is concluded that any assessment of the health or environmental risks should take into account the synergistic interaction between ambient temperature and microwave radiation.

• 대한방사선기술학회지:방사선기술과학
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• 제43권3호
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• pp.169-176
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• 2020

Interventional radiology is performed under real-time fluoroscopy, and patients are exposed to a wide range of exposures for a long period of time depending on the examination and procedure. However, studies on radiation protection for patients during an intervention are insufficient. This study aims to evaluate the doses exposed during the intervention and the applicability of 3D printing materials. The organ dose for each intervention site was evaluated using a monte carlo simulatio. Also, the dose reduction effect of the critical organs was calculated when using a shielding device using 3D printing materials. As a result, the organ dose distribution for each intervention site showed a lower dose distribution for organs located far from the x-ray tube. It was analyzed that the influence of scattered rays was higher in the superficial organs of the back of the human body where x-rays were incident. The dose reduction effect on the critical organ using the 3D printing shield showed the highest testis among the gonads, and in the case of other organs, the dose reduction effect gradually decreased in the order of the eye, thyroid, breast, and ovary. Accordingly, it is judged that the 3D printed shield will be sufficiently usable as a shielding device for the radiation protection of critical organs.